Santa Isabel Vacations from $978

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The Latest Santa Isabel vacation packages

Price found within the past 48 hours. Click for updated prices.
OYO Hotel Brás

OYO Hotel Brás

Bras
$978
per person
Oct 28 - Nov 2
found 1 day ago
Roundtrip flight included
Miami (MIA) to São Paulo (GRU)
8.6/10 Excellent! (39 reviews)
JW Marriott Hotel Sao Paulo

JW Marriott Hotel Sao Paulo

Santo Amaro
$2,293
per person
Nov 22 - Nov 28
found 1 day ago
Roundtrip flight included
Boston (BOS) to São Paulo (GRU)
9.6/10 Exceptional! (445 reviews)
Beyond my expectations I was really happy to stayed in here

Reviewed on Aug 30, 2026

Rosewood Sao Paulo

Rosewood Sao Paulo

Bela Vista
$3,065
per person
Nov 22 - Nov 28
found 1 day ago
Roundtrip flight included
Boston (BOS) to São Paulo (GRU)
9.6/10 Exceptional! (1,297 reviews)
Wonderful Excelente Very good

Reviewed on Sep 15, 2026

You Stay at Vila Olimpia - ITC

You Stay at Vila Olimpia - ITC

Itaim Bibi
$1,612
per person
Nov 22 - Nov 28
found 1 day ago
Roundtrip flight included
Boston (BOS) to São Paulo (GRU)
9.2/10 Wonderful! (223 reviews)
Pullman Sao Paulo Vila Olimpia

Pullman Sao Paulo Vila Olimpia

Itaim Bibi
$1,954
per person
Nov 22 - Nov 28
found 1 day ago
Roundtrip flight included
Boston (BOS) to São Paulo (GRU)
9/10 Wonderful! (1,000 reviews)
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What to do in Santa Isabel

São Paulo: Main City Sights in 7 Hours – Shared Group Tour

São Paulo: Main City Sights in 7 Hours – Shared Group Tour

$76
per adult
98% of travellers recommend
São Paulo: Main City Sights in 7 Hours – Shared Group Tour
São Paulo: Campos do Jordão Guided Tour

São Paulo: Campos do Jordão Guided Tour

$115
per adult
96% of travellers recommend
São Paulo: Campos do Jordão Guided Tour
Visit São Paulo with a local guide

Visit São Paulo with a local guide

$25
per adult
90% of travellers recommend
Visit São Paulo with a local guide
See all activities in Santa Isabel

Santa Isabel Hotel Deals

Hampton by Hilton Guarulhos Airport

Hampton by Hilton Guarulhos Airport

Rua Pedro De Toledo, 1000 Guarulhos
Fully refundableReserve now, pay when you stay
$94 nightly
$99 total
Sep 27 - Sep 28
Total with taxes and fees
Hampton by Hilton Guarulhos Airport
Sleep Inn Guarulhos

Sleep Inn Guarulhos

Avenida Natalia Zarif, 2655 Guarulhos Sao Paulo
Fully refundableReserve now, pay when you stay
$87 nightly
$92 total
Oct 16 - Oct 17
Total with taxes and fees
Sleep Inn Guarulhos
Comfort Hotel Guarulhos - Aeroporto

Comfort Hotel Guarulhos - Aeroporto

R. Pedro de Toledo 977 Guarulhos SP
Fully refundableReserve now, pay when you stay
$98 nightly
$103 total
Oct 1 - Oct 2
Total with taxes and fees
8.6/10 Excellent! (1,887 reviews)
"Very good experience, good people, restaurant and facilities. Geographically close to the airport, but no simple way to get there. So, traffic is horrible in the morning."

Reviewed on Sep 22, 2026

Comfort Hotel Guarulhos - Aeroporto
See all 823 properties in Santa Isabel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santa Isabel Vacation Packages

Santa Isabel Essential Information

Language
Portuguese
Currency
Brazilian reals
Local Welcome
Olá
Local Goodbye
Adeus
Closest Airport
Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU)
Population
33,700
Max Temp Winter
70ºF
Max Temp Summer
80ºF

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Frequently asked questions

How much does a Santa Isabel vacation package cost?
You can grab a vacation package to this top destination from $978 on Expedia. However, how much your vacation to Santa Isabel costs will depend on the season, length of stay and hotel choice.
What are the cheapest months to go to Santa Isabel?
If you're hoping to book a cheap Santa Isabel vacation package, consider visiting in December, January and February. You'll typically find better rates on flights and accommodations during these months — perfect for travelers wishing to save money.
How many days is enough for Santa Isabel?
Generally, a handful of days is enough to see the top attractions during your Santa Isabel vacation. However, if you want to have time to kick back or take day trips, think about extending your itinerary.
How to find the best Santa Isabel package deals?
Finding a cheap Santa Isabel package deal is a cinch with Expedia. After you've entered your destination and travel dates under our "Packages" tab, set your budget range, apply a few filters and browse what's available. You can tweak your search by "Amenities," "Property type," "Popular locations" and more. Sort the results by "Price: low to high" to view the most economical Santa Isabel package deals. Want a simple trick to get even more savings? Have some flexibility with your departure dates and consider traveling on a weekday, when prices are often lower.
Is it cheaper to book a Santa Isabel vacation as a package?
Expedia vacation packages are designed to make your money go further. Bundle your hotel, car rental and flight into one great-value price and enjoy significant savings. You'll generally snag a better deal than booking each component separately. And you'll still have the freedom to create a personalized Santa Isabel vacation by choosing your preferred accommodation type, airline and car class.
When to book a vacation package to Santa Isabel?
If you've got your Santa Isabel vacation dates confirmed, book early to bag some awesome deals. With Expedia, you can often reserve some flights up to a year in advance. Prefer spur-of-the-moment adventures? Our last-minute deals are ideal for impromptu escapes.
Does Expedia offer Book Now, Pay Later Santa Isabel vacation packages?
Your Santa Isabel break is meant to be a relaxing escape from your busy life, not a reason for money worries. So to allow you a bit more flexibility, we've partnered with online lender Affirm to bring you our Book Now, Pay Later vacations. Pick one of our vacation packages with payment plans and split up the cost over 3, 6 or 12 months. Plus, there are no hidden costs or late payment fees to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.