Santo Tomas Vacations from $610
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Your Santo Tomas Vacation
Entertainment, food, art and more … There's a whole lot to discover with a Santo Tomas vacation package. And with the ability to easily customize your city break, it's guaranteed to be one that's hard to forget. If your trip to Santo Tomas includes some sightseeing, hit up well-known attractions like Zócalo, Angel of Independence Monument and Basilica of Our Lady of Guadalupe. Expedia will help you escape your daily routine. Tailor your vacation to Santo Tomas to match your travel style, whatever that may look like.
The Latest Santo Tomas Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Historico Central Hotel
Historic Center
Save 100% on your flight
Price was $994, price is now $610 per person
$610
per person
Oct 15 - Oct 20
found 1 day ago
Roundtrip flight included
Dallas (DFW) to Mexico City (MEX)
9.8/10 Exceptional! (2,335 reviews)
Excelente experiencia, las atenciones del personal te hacen sentir en casa. Sandra mantuvo nuestra habitación impecable, la variedad de comida y la calidad fueron muy buenas. Está muy bien ubicado y nos sentimos seguros en todo momento tanto en el hotel como en el entorno
Reviewed on Sep 2, 2025
Casa de la Luz Hotel Boutique
Historic Center
Price was $2,114, price is now $1,085 per person
$1,085
per person
Nov 7 - Nov 14
just found
Roundtrip flight included
Dallas (DFW) to Mexico City (MEX)
9.6/10 Exceptional! (384 reviews)
Amazing hotel and staff was exceptional. From the front desk attendants and all the other staff, we want to say thank you so much for making our visit memorable. The location was in the middle of the historic district which made it easy to visit many sites. The restaurant in the hotel is also one of the best places we ate during our visit. We will definitely be staying here when we come back. Highly recommended for first time visitors and returning visitors.
Reviewed on Aug 24, 2025
Apartamento en La Condesa
La Condesa
Save 100% on your flight
Price was $2,433, price is now $1,346 per person
$1,346
per person
Oct 15 - Oct 22
found 1 day ago
Roundtrip non-stop flight included
New York (JFK) to Mexico City (MEX)
7.6/10 Good! (4 reviews)
Fantastic location and great space. Wish the TV was a little bigger lol but for the money this place was outstanding. Thanks again.
Reviewed on Aug 11, 2025
Canada Central & Rooftop
Historic Center
Save 100% on your flight
Price was $1,215, price is now $728 per person
$728
per person
Nov 8 - Nov 15
found 1 day ago
Roundtrip flight included
Dallas (DFW) to Mexico City (MEX)
8.4/10 Very Good! (1,002 reviews)
1. With breakfast and snacks included in the package, we saved a significant amount of money not looking for food
2. Ask for the remote for the fan, wish we would have done this on day 1, the rooms get stuffy
3. They are the nicest people we met our entire trip.
Reviewed on Sep 2, 2025
HOTEL LUCA
Roma Norte
Save 100% on your flight
Price was $1,083, price is now $657 per person
$657
per person
Oct 10 - Oct 13
found 1 day ago
Roundtrip flight included
Dallas (DFW) to Mexico City (MEX)
9.2/10 Wonderful! (272 reviews)
Fantastic boutique hotel, highly recommended! Will stay again!
Reviewed on Aug 22, 2025
Where to stay in Santo Tomas
Find the best Santo Tomas areas and neighborhoods for the activities you enjoy most. Learn more about Santo Tomas
Polanco
4.5/5(491 area reviews)
Luxury shopping along Presidente Masaryk Avenue and upscale restaurants await, while nearby Chapultepec Park houses the National Museum of Anthropology and other cultural institutions. Enjoy a stroll in Parque Lincoln or explore Polanquito's vibrant dining scene.
Santo Tomas Hotel Deals
Camino Real Aeropuerto Mexico
Mexico City
Fully refundable
$133 nightly
The price is $159 total per night from Sep 25 to Sep 26
$159 total
Sep 25 - Sep 26
Total with taxes and fees
Camino Real Polanco Mexico
Mariano Escobedo 700, Col Anzures, Mexico City, CDMX
Fully refundableReserve now, pay when you stay
$189 nightly
The price is $226 total per night from Sep 19 to Sep 20
$226 total
Sep 19 - Sep 20
Total with taxes and fees
Barceló México Reforma
Paseo De La Reforma 1, Mexico City
$112 nightly
The price is $133 total per night from Sep 22 to Sep 23
$133 total
Sep 22 - Sep 23
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Santo Tomas
Paseo de la Reforma
Like the Champs Elysées in Paris, this famous wide avenue provides a distinctive elegance to the historic plan of this huge global city.
Zócalo
This is the heart of Mexico City with wide-ranging architecture, cultural events and a lively arts scene.
Basilica of Our Lady of Guadalupe
Mexico’s patron saint, the Virgin of Guadalupe, is believed to have appeared on the site of this church, making it an important pilgrimage site for many Catholics.
Things to do
Explore the Real MxCity all-inclusive
$51
per adult
100% of travellers recommend
Frida Kahlo & Anahuacalli Museum Ticket with Digital Guide
$74
per adult
80% of travellers recommend
Explore a world of travel with Expedia
Explore a world of travel with Expedia
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- Mexico City Hotels
- Hospital de Jesus Nazareno
- Visit Azcapotzalco
- Mexico City Arena
- Visit Industrial Vallejo
- La Raza Medical Center
- Planetario Luis Enrique Erro
- Basilica of Our Lady of Guadalupe
- Mexico City Vacations
- Visit Lindavista
- Visit Santa Maria la Ribera
- Casa de los Condes de Heras y Soto
- Funny Land
- Forum Buenavista
- Buenavista Vacations
- Pemex Tower
- Museo Universitario del Chopo
- San Rafael Vacations
- Visit Buenavista
- Visit Cuauhtémoc
- Tlatelolco Archaelogical Site
- Plaza de las Tres Culturas
- Visit San Rafael
- Soumaya Museum
- Hospital Español
- Jumex Museum
- Visit Polanco
- Visit Downtown Mexico City
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.