One of your first stops should be Visitor Center Orfento Valley. Here, you'll be able to orient yourself and get some great tips before you set out exploring.
Situated in Caramanico Terme, this tourist information center is worth a visit. But you'll find lots more to check out in this area. Maiella Massif, Majelletta We Ski, and Parco del Lavino aren't too far away from Visitor Center Orfento Valley.