$647 Cheap Flights from Santo Domingo (SDQ) to Lisbon (LIS)

View $647 flight on Tue, May 12, 2026Opens in a new window

Popular airlines from Las Americas Intl. Airport (SDQ) to Humberto Delgado Airport (LIS)

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Cheap Flights from Santo Domingo to Lisbon (SDQ-LIS)

Prices were available within the past 7 days and start at $647 for one-way flights and $982 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Iberia
Sat, Oct 11 - Mon, Oct 20
SDQ
Santo Domingo
LIS
Lisbon
$982 Roundtrip, found 4 days ago
$982
Roundtrip
found 4 days ago
Select Iberia flight, departing Sat, Oct 11 from Santo Domingo to Lisbon, returning Mon, Oct 20, priced at $982 found 4 days ago
Iberia
Sat, Oct 11 - Mon, Oct 20
SDQ
Santo Domingo
LIS
Lisbon
$990 Roundtrip, found 4 days ago
$990
Roundtrip
found 4 days ago
Select Iberia flight, departing Sat, Oct 11 from Santo Domingo to Lisbon, returning Mon, Oct 20, priced at $990 found 4 days ago
Iberia
Thu, Sep 18 - Wed, Sep 24
SDQ
Santo Domingo
LIS
Lisbon
$993 Roundtrip, found 3 days ago
$993
Roundtrip
found 3 days ago
Select Iberia flight, departing Thu, Sep 18 from Santo Domingo to Lisbon, returning Wed, Sep 24, priced at $993 found 3 days ago
Air Europa
Mon, Sep 22 - Tue, Oct 7
SDQ
Santo Domingo
LIS
Lisbon
$1,000 Roundtrip, found 18 hours ago
$1,000
Roundtrip
found 18 hours ago
Select Air Europa flight, departing Mon, Sep 22 from Santo Domingo to Lisbon, returning Tue, Oct 7, priced at $1,000 found 18 hours ago
Iberia
Mon, Sep 22 - Sat, Oct 4
SDQ
Santo Domingo
LIS
Lisbon
$1,001 Roundtrip, found 5 days ago
$1,001
Roundtrip
found 5 days ago
Select Iberia flight, departing Mon, Sep 22 from Santo Domingo to Lisbon, returning Sat, Oct 4, priced at $1,001 found 5 days ago
Iberia
Thu, Sep 18 - Wed, Sep 24
SDQ
Santo Domingo
LIS
Lisbon
$1,001 Roundtrip, found 3 days ago
$1,001
Roundtrip
found 3 days ago
Select Iberia flight, departing Thu, Sep 18 from Santo Domingo to Lisbon, returning Wed, Sep 24, priced at $1,001 found 3 days ago
Air Europa
Tue, Sep 30 - Tue, Oct 14
SDQ
Santo Domingo
LIS
Lisbon
$1,002 Roundtrip, found 18 hours ago
$1,002
Roundtrip
found 18 hours ago
Select Air Europa flight, departing Tue, Sep 30 from Santo Domingo to Lisbon, returning Tue, Oct 14, priced at $1,002 found 18 hours ago
American Airlines
Sun, Jan 11 - Tue, Jan 27
SDQ
Santo Domingo
LIS
Lisbon
$1,160 Roundtrip, found 2 days ago
$1,160
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sun, Jan 11 from Santo Domingo to Lisbon, returning Tue, Jan 27, priced at $1,160 found 2 days ago
United
Tue, Jan 27 - Tue, Feb 10
SDQ
Santo Domingo
LIS
Lisbon
$1,164 Roundtrip, found 2 days ago
$1,164
Roundtrip
found 2 days ago
Select United flight, departing Tue, Jan 27 from Santo Domingo to Lisbon, returning Tue, Feb 10, priced at $1,164 found 2 days ago
KLM
Sun, Jul 6 - Thu, Jul 17
SDQ
Santo Domingo
LIS
Lisbon
$1,208 Roundtrip, found 4 days ago
$1,208
Roundtrip
found 4 days ago
Select KLM flight, departing Sun, Jul 6 from Santo Domingo to Lisbon, returning Thu, Jul 17, priced at $1,208 found 4 days ago

Find the cheapest month to fly from Santo Domingo (SDQ) to Lisbon (LIS)

March is typically the cheapest month to fly

From $810 - $1,276 per traveler.

Graph displaying average flight prices per month

Flights from Santo Domingo (SDQ) to Lisbon (LIS)
Origin airport
Las Americas Intl.
Destination airport
Humberto Delgado
Airlines serving
Air Europa, Air France, American Airlines, Iberia, KLM, United
Roundtrip price
$982
Distance
3857 mi

Santo Domingo to Lisbon Flights

The cheapest times to fly from Santo Domingo to Lisbon

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santo Domingo to Lisbon are during the month of October. You can find some of the cheapest flights from Santo Domingo to Lisbon with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Santo Domingo to Lisbon

Sunday is one of the best days to book for cheap flights from Santo Domingo to Lisbon: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Santo Domingo to Lisbon

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santo Domingo to Lisbon in 2025. You can also book with separate airlines for your outbound and return journeys, from $647 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santo Domingo to Lisbon flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Santo Domingo to Lisbon airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Las Americas Intl. Airport (SDQ) to Humberto Delgado Airport (LIS) cost?
Discover the latest flight deals from SDQ to LIS by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from SDQ to LIS?
The cheapest flights from SDQ to LIS are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from SDQ to LIS?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from SDQ to LIS. Sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from Las Americas Intl. Airport (SDQ) to Humberto Delgado Airport (LIS)?
There aren't any daily direct flights from Las Americas Intl. Airport (SDQ) to Humberto Delgado Airport (LIS). But you can choose flights with layovers. Filter your search results on Expedia to include one or two stops, and you'll be on your way in no time.
What day of the week has the most flights from SDQ to LIS?
Usually you'll find the largest variety of flight choices on a Friday. Tuesdays tend to be the quietest.* However, this can change depending on the season, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Las Americas Intl. Airport (SDQ) to Humberto Delgado Airport (LIS)?
To avoid possible delays on the Las Americas Intl. Airport (SDQ) to Humberto Delgado Airport (LIS) route, aim to fly before 3 PM. Later flights have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Las Americas Intl. Airport (SDQ) to Humberto Delgado Airport (LIS) last-minute?
Last-minute fares from SDQ to LIS are usually more expensive. To lock in the best prices, start looking for flights ahead of time. That being said, if you're flexible with your travel plans, it's possible to score a cheap fare right before you leave.
Is it cheaper to book a SDQ to LIS flight and hotel package?
Compared with arranging hotels and flights separately, booking a SDQ to LIS flight and hotel package with Expedia could lead to significant savings. What's more, having it all in one place will take the hassle out of travel planning. Just pick your flights and select from our extensive range of hotels, then personalize your trip with extras like car rentals and activities.
Can I cancel or change the date of my flight from Las Americas Intl. Airport (SDQ) to Humberto Delgado Airport (LIS)?
Generally, it's possible to cancel or reschedule your SDQ to LIS flight. However, for bookings made more than 24 hours ago, additional charges may apply. Check your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find more details on our Customer Service portal.

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*Available to One Key members.