Santo Antonio

Travel Guide

A riverside promenade with cafes, trees, and buildings.
A row of parked motorcycles in front of a building with ornate architecture and multiple Prada store entrances.
A statue of a woman holding a spear, with a child at her feet, in front of a building with balconies and flags.
A building with a sign reading "Blue Liberdade Hotel" and balconies with black railings.
Storefronts including TOD'S, GUESS, and VACHERON CONSTANTIN.
Locke de Santa Joana

Locke de Santa Joana

4 out of 5
18 Rua Camilo Castelo Branco Lisbon
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $105 total per night from Nov 30 to Dec 1
$105 total
Nov 30 - Dec 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Lisbon. Enjoy an outdoor pool, 2 restaurants, and 3 bars/lounges. Popular attractions Avenida da Liberdade and ...
Locke de Santa Joana
easyHotel Lisbon

easyHotel Lisbon

2 out of 5
R. de Santa Marta 60 Lisbon
$52 nightly
The price is $64 total per night from Nov 22 to Nov 23
$64 total
Nov 22 - Nov 23
Total with taxes and fees
Stay at this hotel in Lisbon. Enjoy breakfast (surcharge), parking (surcharge), and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms ...
easyHotel Lisbon
EPIC SANA Marques Hotel

EPIC SANA Marques Hotel

5 out of 5
Avenida Fontes de Pereira de Melo, 8 Lisbon
$225 nightly
The price is $248 total per night from Dec 4 to Dec 5
$248 total
Dec 4 - Dec 5
Total with taxes and fees
Book a stay at this luxury hotel in Lisbon. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
EPIC SANA Marques Hotel
See all 640 properties in Santo Antonio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Numa Lisbon Rato

Numa Lisbon Rato

3.5 out of 5
58 Rua Alexandre Herculano Lisbon
Stay at this aparthotel in Lisbon. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Popular attractions Avenida da Liberdade and Rossio Square ...
9.2/10 Wonderful! (264 reviews)
"Clean Quiet room !!"

Reviewed on Nov 6, 2026

Numa Lisbon Rato
Altis Prime Hotel de Apartamentos

Altis Prime Hotel de Apartamentos

4 out of 5
Rua Rodrigo da Fonseca, 4 Lisbon
Book a stay at this family-friendly aparthotel in Lisbon. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff ...
9.4/10 Exceptional! (954 reviews)
"I think the queen bed is a bit smaller. Also, too soft for our back. Very clean property. Friendly staff who even came out to help us with luggage when he saw us at the door."

Reviewed on Nov 8, 2026

Altis Prime Hotel de Apartamentos
LSA Liberdade by Numa

LSA Liberdade by Numa

4 out of 5
Rua Mouzinho da Silveira, 34-36 Lisbon
Stay at this apartment in Lisbon. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Popular attractions Avenida da Liberdade and Rossio Square ...
8.8/10 Excellent! (1,205 reviews)
"Clean room, staff…"

Reviewed on Nov 1, 2026

LSA Liberdade by Numa
See all properties in Santo Antonio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Santo Antonio attractions

A city square with a fountain, trees, and a building with 'SAO JOSE' signage.

Avenida da Liberdade

9.4/10 (3,467 reviews)
You can browse for souvenirs when you visit Avenida da Liberdade, a popular shopping spot in Santo Antonio. Discover the top-notch restaurants in this romantic area, or seek out the local tours.
See properties

Things to do

Belem Tower

Tour Lisbon: Belém Tower, the Cathedral & Parque das Nações

$87
per adult
94% of travellers recommend
Tour Lisbon: Belém Tower, the Cathedral & Parque das Nações
Tastes & Traditions of Lisbon Food Tour

Tastes & Traditions of Lisbon Food Tour

$71
per adult
100% of travellers recommend
Tastes & Traditions of Lisbon Food Tour
Lisbon: Sintra, Regaleira, Pena, Cabo Roca All Tickets Included

Lisbon: Sintra, Regaleira, Pena, Cabo Roca All Tickets Included

$40
per adult
88% of travellers recommend
Lisbon: Sintra, Regaleira, Pena, Cabo Roca All Tickets Included
Lisbon: Sunset Boat Party Cruise with DJ and Open Bar

Lisbon: Sunset Boat Party Cruise with DJ and Open Bar

$39
per adult
Lisbon: Sunset Boat Party Cruise with DJ and Open Bar
Picture 3 for Activity Lisbon: Guided Day Tour of Sintra, Pena, Regaleira & Cascais

Lisbon: Sintra, Pena, Regaleira & Cabo Roca & Cascais Coast

$40
per adult
92% of travellers recommend
Lisbon: Sintra, Pena, Regaleira & Cabo Roca & Cascais Coast
Lisbon: Cook 3 Portuguese Classics with Wine & Ginja

Lisbon: Cook 3 Portuguese Classics with Wine & Ginja

$67
per adult
90% of travellers recommend
Lisbon: Cook 3 Portuguese Classics with Wine & Ginja
See all activities in Santo Antonio

Frequently asked questions

Is Santo Antonio worth visiting?
Santo Antonio is worth visiting for its standout attractions, including the beautiful Avenida da Liberdade and the tranquil Botanical Garden. Travelers also benefit from practical transit access, with convenient metro and train options making it easy to explore the area and beyond.
What is Santo Antonio known for?
Santo Antonio is known for its significant landmarks, including Avenida da Liberdade, a prominent avenue. Travelers can also explore the serene Botanical Garden and visit the Coracao de Jesus. It is a city in Portugal that offers these notable sites.
What is a good itinerary length for Santo Antonio?
A good itinerary length for Santo Antonio is two to three days to explore nearby highlights like Avenida da Liberdade, the Botanical Garden, and Coracao de Jesus, perhaps with a Lisbon Tuk Tuk Tour. An extended stay of four to five days allows for deeper exploration, including a Craft Beer, Port & Wine Tour and a City Discovery Game. See Santo Antonio Activities.
How do you get around Santo Antonio?
In Santo Antonio, travelers can easily get around using the metro. Key stations like Marques de Pombal Station, Rato Station, and Avenida Station provide convenient access. For exploring further, rental cars are available in Lisbon City Center. Rideshare services also offer a flexible option for getting to various destinations.
What are the top things to do in and around Santo Antonio?
In Santo Antonio, travelers can enjoy a mix of city exploration, cultural sites, and regional excursions:

  • Tour Lisbon by Tuk Tuk with Food Tastings.
  • Visit Sintra and Pena Palace on a half-day tour.
  • Explore the Botanical Garden.
  • Discover the Cinemateca Portuguesa Museum.
  • Enjoy a Craft Beer, Port & Wine Tour.

How do I plan a trip to Santo Antonio?
To plan your trip to Santo Antonio, search for places to stay on Expedia. Book your flights and activities like the Lisbon Tuk Tuk Tour or a Craft Beer, Port & Wine Tour in advance. You can easily get around using the metro and train, so a rental car is optional. Explore areas like Avenida da Liberdade and the Botanical Garden.
Can I book a refundable hotel in Santo Antonio?
Yes, Expedia offers many flexible booking options, and you can look for refundable hotels in Santo Antonio by entering your dates and using the refundable or fully refundable filter. Always check the hotel's cancellation policy before you book, since terms can vary by hotel, and visit Expedia help center for further details.
Why book a trip to Santo Antonio with Expedia?
Expedia makes it easier to plan your Santo Antonio trip with travel tools, flexible search options, and bookable trip components all in one place. You can organize your plans in one account and use Expedia to help build a trip that fits your budget and travel style. Find out more about how by visiting Expedia's Trip Planner page.
Should I stay in a hotel or vacation rental in Santo Antonio?
The best choice depends on your travel style. Hotels in Santo Antonio can be a good fit for convenience, on-site amenities, and shorter stays, while vacation rentals may offer more space, privacy, and home-style amenities for longer trips, families, or groups. With Expedia, you can compare both options side by side, read traveler reviews, and filter by amenities to find the right fit for your trip.
How can I manage my Santo Antonio trip on Expedia?
Once you've booked your Santo Antonio trip, you can manage it through your Expedia account or the Expedia app. You can view your itinerary, access booking details, make eligible changes, and check for updates in My Trips. The Expedia app can also help you stay organized while you travel.
What if I need help during my Santo Antonio trip?
Expedia offers customer support before, during, and after your Santo Antonio trip. If your plans change or something unexpected happens, you can review your booking in My Trips and use Expedia help center channels for help with eligible changes, cancellations, or travel issues.
How can Expedia help me plan my first trip to Santo Antonio?
If it's your first trip to Santo Antonio, Expedia can help you plan by bringing together stays, flights, activities, traveler reviews, and trip-planning tools in one place. With Expedia's Trip Planner you can compare options, read reviews from other travelers, and build an itinerary that matches your interests and budget.
How can I save on my Santo Antonio hotel booking with Expedia?
Join One Key™ for free to unlock instant discounts with Member Prices on select hotels. You can also earn and use OneKeyCash™* on eligible bookings on Expedia. Booking in advance is usually another great way to save on your Santo Antonio hotel.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.

Cities near Santo Antonio

A coastal cityscape with colorful buildings and a prominent white dome structure.

Lisbon

A coastal cityscape with terracotta-roofed buildings, a prominent white church, and a view of the sea and distant city lights.

Lisbon District

A cityscape with a prominent bridge, dense urban buildings, and a hilly backdrop.

Campo de Ourique

A street lined with multi-story residential buildings, a bus stop, and parked cars.

Areeiro

Explore a world of travel with Expedia