$293 Cheap Flights from Buffalo (BUF) to Key West (EYW)

View $293 flight on Tue, Jun 9, 2026Opens in a new window

Popular airlines from Buffalo Niagara Intl. Airport (BUF) to Key West Intl. Airport (EYW)

Cheap Flights from Buffalo to Key West (BUF-EYW)

Prices were available within the past 7 days and start at $293 for one-way flights and $323 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Sat, May 30 - Wed, Jun 3
BUF
Buffalo
EYW
Key West
$323 Roundtrip, found 12 hours ago
$323
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Sat, May 30 from Buffalo to Key West, returning Wed, Jun 3, priced at $323 found 12 hours ago
American Airlines
Sat, May 2 - Wed, May 6
BUF
Buffalo
EYW
Key West
$328 Roundtrip, found 4 days ago
$328
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, May 2 from Buffalo to Key West, returning Wed, May 6, priced at $328 found 4 days ago
Delta
Mon, Apr 13 - Tue, Apr 21
BUF
Buffalo
EYW
Key West
$336 Roundtrip, found 4 hours ago
$336
Roundtrip
found 4 hours ago
Select Delta flight, departing Mon, Apr 13 from Buffalo to Key West, returning Tue, Apr 21, priced at $336 found 4 hours ago
Delta
Tue, Jan 12 - Wed, Jan 20
BUF
Buffalo
EYW
Key West
$343 Roundtrip, found 2 days ago
$343
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Jan 12 from Buffalo to Key West, returning Wed, Jan 20, priced at $343 found 2 days ago
American Airlines
Thu, Jul 23 - Thu, Jul 30
BUF
Buffalo
EYW
Key West
$349 Roundtrip, found 4 hours ago
$349
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Thu, Jul 23 from Buffalo to Key West, returning Thu, Jul 30, priced at $349 found 4 hours ago
American Airlines
Fri, Dec 4 - Wed, Dec 9
BUF
Buffalo
EYW
Key West
$354 Roundtrip, found 1 day ago
$354
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Dec 4 from Buffalo to Key West, returning Wed, Dec 9, priced at $354 found 1 day ago
American Airlines
Tue, Nov 3 - Tue, Nov 10
BUF
Buffalo
EYW
Key West
$359 Roundtrip, found 2 days ago
$359
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Nov 3 from Buffalo to Key West, returning Tue, Nov 10, priced at $359 found 2 days ago
Delta
Mon, Oct 26 - Sat, Oct 31
BUF
Buffalo
EYW
Key West
$361 Roundtrip, found 1 day ago
$361
Roundtrip
found 1 day ago
Select Delta flight, departing Mon, Oct 26 from Buffalo to Key West, returning Sat, Oct 31, priced at $361 found 1 day ago
United
Sat, May 30 - Wed, Jun 3
BUF
Buffalo
EYW
Key West
$365 Roundtrip, found 12 hours ago
$365
Roundtrip
found 12 hours ago
Select United flight, departing Sat, May 30 from Buffalo to Key West, returning Wed, Jun 3, priced at $365 found 12 hours ago
JetBlue Airways
Sat, Oct 10 - Sat, Oct 17
BUF
Buffalo
EYW
Key West
$555 Roundtrip, found 3 hours ago
$555
Roundtrip
found 3 hours ago
Select JetBlue Airways flight, departing Sat, Oct 10 from Buffalo to Key West, returning Sat, Oct 17, priced at $555 found 3 hours ago

Alternative airports near Key West

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Key West Intl. EYW. Cheapest and Closest option available. Average driving time to city center is 8 minutes. Flights from $757
EYW
Key West Intl.
CheapestClosest
Average driving time to city center8 min
Flights from $757

Find the cheapest month to fly from Buffalo (BUF) to Key West (EYW)

May is typically the cheapest month to fly

From $212 - $557 per traveler.

Frequently asked questions

How much does a flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Key West, FL (EYW-Key West Intl.) cost?
You can find cheap one-way flights from $293 and cheap return flights from $323 Buffalo, NY (BUF-Buffalo Niagara Intl.) to Key West, FL (EYW-Key West Intl.) with Expedia. One-way flights generally range between $265 and $1140, and roundtrip flights usually range from $385 to $1417. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Buffalo, NY (BUF-Buffalo Niagara Intl.) to Key West, FL (EYW-Key West Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Key West, FL (EYW-Key West Intl.)?
August is the cheapest month to fly from Buffalo, NY (BUF) to Key West, FL (EYW), with average return fares around $376. This is about 19% lower than the average price throughout the year, as August tends to be less busy for travel. Other budget-friendly months include January and September.*Averages based on flights available on Expedia in the last year.
Which airlines fly direct from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Key West, FL (EYW-Key West Intl.)?
Enter BUF to EYW and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Key West, FL (EYW-Key West Intl.)?
American Airlines is one of the cheapest airlines offering connecting flights from Buffalo (BUF) to Key West (EYW) with a layover in Ronald Reagan Washington National (DCA), starting from around $753. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Key West, FL (EYW-Key West Intl.)?
To find a cheap flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Key West, FL (EYW-Key West Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Key West, FL (EYW-Key West Intl.)?
The best months to fly from Buffalo (BUF) to Key West (EYW) are August and September. Return flights during these months average around $376, providing a great value. August is perfect for summer getaways, while September sees fewer crowds, enhancing your travel experience.*Prices based on flights available on Expedia in the last year.
What is the earliest flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Key West, FL (EYW-Key West Intl.)?
The earliest flight from Buffalo, NY (BUF) to Key West, FL (EYW) generally departs at around 5:00 AM, operated by American Airlines. This service is seasonal and active in December, making an early departure a great way to enjoy more time in sunny Key West. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Key West, FL (EYW-Key West Intl.)?
The most popular departure times for flights from Buffalo Niagara Intl. (BUF) to Key West Intl. (EYW) are in the early morning, from 6am to 9am. About 55% of passengers prefer this time window. Many major carriers, including American Airlines and Delta Airlines, offer flights during this window. This timing is favored as it allows you to start your day early and arrive in Key West ready to enjoy the beach.
How long does it take to fly from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Key West, FL (EYW-Key West Intl.)?
A flight from BUF to EYW with a layover takes around 7 hours 20 minutes, with the route covering approximately 1,282 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Key West, FL (EYW-Key West Intl.)?
First class seats are offered on the BUF to EYW route. First class cabins are available on:

  • Delta Air Lines
  • American Airlines
  • United Airlines

How do I earn miles on a Buffalo, NY (BUF-Buffalo Niagara Intl.) to Key West, FL (EYW-Key West Intl.) flight with Expedia?
It's easy to earn miles on a Buffalo, NY (BUF-Buffalo Niagara Intl.) to Key West, FL (EYW-Key West Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Key West from Buffalo Niagara Intl. (BUF)?
If you're planning to travel to Key West from Buffalo Niagara Intl. (BUF), you can fly into Key West Intl. (EYW) Some flights may connect through major hubs like LaGuardia (LGA), Ronald Reagan Washington National (DCA), Charlotte-Douglas Intl. (CLT) before reaching Key West. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Key West, FL (EYW-Key West Intl.) at the last minute?
Typically, booking a last minute flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Key West, FL (EYW-Key West Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Buffalo, NY (BUF-Buffalo Niagara Intl.) to Key West, FL (EYW-Key West Intl.) flight and hotel package?
Securing a Buffalo, NY (BUF-Buffalo Niagara Intl.) to Key West, FL (EYW-Key West Intl.) Key West Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Key West, FL (EYW-Key West Intl.)?
If you booked your Buffalo, NY (BUF-Buffalo Niagara Intl.) to Key West, FL (EYW-Key West Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Buffalo Niagara Intl.
Destination airport
Key West Intl.
Airlines serving
American Airlines, Delta, JetBlue Airways, United
Roundtrip price
$322
Distance
1281 mi

Book with confidence

Buffalo to Key West Flights

The cheapest times to fly from Buffalo to Key West

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Buffalo to Key West are during the month of May. You can find some of the cheapest flights from Buffalo to Key West with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Buffalo to Key West

Sunday is one of the best days to book for cheap flights from Buffalo to Key West: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Buffalo to Key West

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Buffalo to Key West in 2026. You can also book with separate airlines for your outbound and return journeys, from $293 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Buffalo to Key West flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Buffalo to Key West airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Buffalo to Key West Flights

*Flight schedules are subject to change.

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*Available to One Key members.