Find 4 Star Hotels in Key West

Search over 1 million properties and 550 airlines worldwide

Members save 10% more on select hotels, cars, activities and vacation rentals. Sign up.

Free cancellation on most hotels. Because flexibility matters.

Top Key West 4 Star Hotels

Southernmost Beach Resort
4 out of 5
1319 Duval Street, Key West, FL
Free CancellationReserve now, pay when you stay
The price is $220 per night
4.2/5Excellent! (2,534 reviews)

"Southernmost was a safe choice for us as it was our first time in KW. Our room was tidy and comfortable; we requested an oceanfront room and were close to the sunbathing deck and pool. The staff was welcoming and very hospitable. If you are selecting this property because of the beach, do not. It ..."…"

Reviewed on Aug 5, 2020

Southernmost Beach Resort
24 North Hotel Key West
4 out of 5
3820 North Roosevelt Boulevard, Key West, FL
Free CancellationReserve now, pay when you stay
The price is $111 per night
4/5Very Good! (1,367 reviews)

"Very clean, great location with great views. Staff is awesome. I will definitely stay here again."…"

Reviewed on Jul 26, 2020

24 North Hotel Key West
Pier House Resort & Spa
4 out of 5
1 Duval St, Key West, FL
Free CancellationReserve now, pay when you stay
The price is $189 per night
4.5/5Wonderful! (965 reviews)

"Great service . I’ll definitely be back there when I go to Key west . Perfect location ."…"

Reviewed on Aug 8, 2020

Pier House Resort & Spa
The Gates Hotel Key West
4 out of 5
3824 N Roosevelt Blvd, Key West, FL
Free CancellationReserve now, pay when you stay
The price is $115 per night
4.2/5Excellent! (1,004 reviews)

"Friendly staff and clean rooms . Even with the short staff they have during COVID-19, they were still quick to accommodate us with any of our extra needs . The shuttle for the hotel is nice and runs every hour . Also ,If you get the trolly tickets they pick up and drop off in the empty parking lot ..."…"

Reviewed on Aug 9, 2020

The Gates Hotel Key West
Crowne Plaza Key West-La Concha
4 out of 5
430 Duval St, Key West, FL
Free Cancellation
The price is $123 per night
4.1/5Very Good! (976 reviews)

"Property is very nice, it’s very unfortunate because of the China Covid all the restaurants, bars and room service are temporarily closed. Otherwise wise the hotel is great and the location is in the middle of the Key West life on Duval Street. Definitely recommend for young couples and singles. ..."…"

Reviewed on Aug 9, 2020

Crowne Plaza Key West-La Concha
Casa Marina Key West, A Waldorf Astoria Resort
4 out of 5
1500 Reynolds Street, Key West, FL
Free CancellationReserve now, pay when you stay
The price is $220 per night
3.7/5Good! (985 reviews)

"It’s a good property, but for 4 adult the bed is very small and the price is not totally clear when you reserve"…"

Reviewed on Aug 5, 2020

Casa Marina Key West, A Waldorf Astoria Resort
Margaritaville Key West Resort & Marina
4 out of 5
245 Front Street, Key West, FL
Free CancellationReserve now, pay when you stay
The price is $200 per night
4.3/5Excellent! (1,050 reviews)

"Nice place to stay. Great location. Good layout nice pool area"…"

Reviewed on Aug 4, 2020

Margaritaville Key West Resort & Marina
Oceans Edge Key West Resort, Hotel & Marina
4 out of 5
5950 Peninsular Avenue, Key West, FL
Free CancellationReserve now, pay when you stay
The price is $143 per night
4.5/5Wonderful! (2,395 reviews)

"We stayed here two weeks ago for our honeymoon and LOVED it! The hotel was very clean and the staff was super friendly! Will definitely stay there again!"…"

Reviewed on Jul 19, 2020

Oceans Edge Key West Resort, Hotel & Marina
The Marker Key West Harbor Resort
4 out of 5
200 William Street, Key West, FL
Free CancellationReserve now, pay when you stay
The price is $186 per night
4.4/5Wonderful! (987 reviews)

"The hotel was nice and right on the harbor. The pools were beautiful and taken care of and we had a great view of the pool and palm tree from our balcony. They provided champagne and chocolates for my 30th birthday stay which was nice also. Obviously COVID made things a bit different-including certain ..."…"

Reviewed on Jul 29, 2020

The Marker Key West Harbor Resort
Hyatt Centric Key West Resort and Spa
4 out of 5
601 Front St, Key West, FL
Free CancellationReserve now, pay when you stay
The price is $229 per night
4.4/5Excellent! (995 reviews)

"Hotel was very clean. Staff very friendly. Rooms were nice and up to date. Great location to the water activities at the marina. Will definitely stay here again."…"

Reviewed on Aug 4, 2020

Hyatt Centric Key West Resort and Spa
Don't see what you're looking for?
See all available properties in Key West
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

The get-go of any much-needed holiday starts with selecting a spot. Key West has been a popular local with tourists because it offers so much to see and do. Yet, "location, location, location" applies to more than just your vacation destination. When you want to make your holiday especially memorable, it's all about where you start each new day.

Lodgings as Stunning as the City

Key West saw its fair share of visitors this past year. Our review section provides reviews which may help you choose which resort is ideal for your holiday. When you book a 4-star suite you can relax knowing that these properties aim to meet your needs. You won't need to search long for a refreshing swim, gourmet lunch, or to sustain your workout schedule during your vacation, thanks to everything these hotels provide. They aim to make the facilities and grounds welcoming from the moment you step out of your car and with every step throughout the hotel. Key West has dozens of marvelous hotels that create the absolute perfect holiday.

Rooms have been designed to keep your utmost comfort in mind, with amenities like ultra-comfortable bedding, and in-room coffee or tea, and designer bathroom products. So, lay back and unwind. Moreover, if you find that you are need of anything further, you can rest easy the staff will work their best to ensure you remain pleased during your stay. These properties are so lovely that you'll regret the day you have to check-out.

Book a 4-Star Hotel in Key West Today!

A holiday to Key West should be one that you'll recollect for years to come, and booking a 4-star hotel will help create memories that are nothing but fantastic. Make sure to book soon. With so few accommodations, and plenty of people desiring to travel to Key West, you may miss out on your perfect room.

More trip options