Southern Minnesota Luxury Vacations

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4 Night Luxury vacations in Southern Minnesota

Price found within the past 48 hours. Click for updated prices.
Aspen Select

Aspen Select

Kutzky Park
$629
per person
Dec 27 - Dec 31
found 17 hours ago
Roundtrip non-stop flight included
Syracuse (SYR) to Rochester (RST)
8.4/10 Very Good! (1,000 reviews)
Alexander Mansion Bed and Breakfast

Alexander Mansion Bed and Breakfast

Historic Downtown Winona
$1,091
per person
Dec 14 - Dec 18
found 15 hours ago
Roundtrip non-stop flight included
Billings (BIL) to Rochester (RST)
9.8/10 Exceptional! (554 reviews)
My stay at this wonderful Mansion was truly memorable—from the heartwarming, homemade breakfast prepared by the owner, to the stories they shared about the building’s history. I would love to stay here again.

Reviewed on Oct 18, 2026

Red Wing Inn and Suite

Red Wing Inn and Suite

$1,047
per person
Dec 14 - Dec 18
found 1 day ago
Roundtrip non-stop flight included
Billings (BIL) to Minneapolis (MSP)
7/10 Good! (435 reviews)
We really liked the jetted tub. We didn’t like the loud furnace fan which seemed to come on every few minutes.

Reviewed on Oct 18, 2026

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All you need to know about luxury vacations in Southern Minnesota

What can I expect from a luxury Southern Minnesota vacation?

Luxury means the very finest of the things you enjoy most. Indulge your every waking moment—and restful night—with a luxury Southern Minnesota vacation. Sip handcrafted cocktails by an infinity pool, sink into bliss at a full-service spa with a massage cabana on the beach, and chat, cheers, and laugh through exquisite breakfasts, lunches, and dinners with spectacular views. 

How can I find all-inclusive luxury vacation packages in Southern Minnesota?

By refining your filters, the most opulent all-inclusive vacation packages will appear before your eyes. Check the 5* filter to find truly sensational stays. You barely need to lift a finger. 

Can I book a cheap Southern Minnesota luxury vacation?

Affordable luxury is only ever a few clicks away. Enter your travel dates and sort the grandiose getaways on offer by price to see the most fiscally friendly retreats first. Filter by budget, too, to find your perfect balance of luxury. Right now, luxury vacations start at $629. Prices and availability are subject to change. Additional terms may apply.

How can I book a luxury family vacation in Southern Minnesota?

Tailor your luxury family escape by checking the filters that set the whole family’s hearts a-flutter. Whether that’s wet and wild water parks, heavenly hot tubs, or the kid-quieting magic of free Wi-Fi. 

Can I book a package in Southern Minnesota with a luxury vacation home?

A private paradise is true luxury! Filter by property type for houses, villas, and apartments. For an amazingly affordable all-in-one luxury experience, book your accommodation, airfare, and car rental as a package.   

How can I find the best luxury vacation deals in Southern Minnesota?

Find absolute delight in the dropdown! Simply sort your tempting search results by deals to find that lean-budget luxury. For a budget conscious stay, consider booking a stay away from big cities or outside the peak months.

Can I book a luxury holiday in Southern Minnesota with free cancellation and/or flexible dates?

Freedom and flexibility are the greatest luxuries of all. Get both when you filter by payment option and book a trip with free cancellation or on a buy now, pay later plan. 

Why should I book my luxury trip to Southern Minnesota with Expedia?

A luxurious trip follows a stress-free booking experience. Find, build, and book the most glorious of getaways in seconds—with ATOL protection for added peace of mind.

Top Luxury Southern Minnesota Hotels

Kahler Grand Hotel

Kahler Grand Hotel

20 2nd Ave Sw Rochester MN
  • 2 min walk from Mayo Clinic
Kahler Grand Hotel offers luxe lodging where you'll enjoy premium bedding and more. Deluxe amenities at this hotel include an indoor pool, a 24-hour fitness ...
Kahler Grand Hotel
AmericInn by Wyndham Blue Earth

AmericInn by Wyndham Blue Earth

1495 Domes Dr Blue Earth MN
  • 5 hours drive from Mayo Clinic
Go for a luxurious stay at AmericInn by Wyndham Blue Earth, where you can enjoy amenities like 24-hour room service, premium channels, and more.
AmericInn by Wyndham Blue Earth
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

435 16th Ave Nw Rochester MN
  • 26 min walk from Mayo Clinic
Indulge yourself with upscale accommodations at Med City Inn & Suites - Mayo Clinic Area, where you'll enjoy amenities like premium channels and more. Notable ...
Med City Inn & Suites - Mayo Clinic Area
See all 1,236 properties in Southern Minnesota
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.