Find luxury hotels in Key West, FL

Most hotels are fully refundable. Because flexibility matters.

Save 10% or more on over 100,000 hotels worldwide as a One Key member.

Search over 2.9 million properties and 550 airlines worldwide.

Find properties with these dates

Pick from 64 Key West Luxury Hotels and compare room rates, reviews, and availability. Most hotels are fully refundable.

Deluxe Suite, 1 King Bed, Private Pool | View from room
H2O Suites - Adults Only
3.5 star property
9.8 out of 10, Exceptional, (477)
"Highly recommend this hotel. The staff are pleasant, accommodating, and gave great recommendations for dinning. The entire hotel was super clean, quiet, and located close to Duval street. Will definitely stay here again! "
The price is $479
$584 total
includes taxes & fees
May 27 - May 28
H2O Suites - Adults Only
Courtyard
Santa Maria Suites
4.0 star property
9.6 out of 10, Exceptional, (1001)
"It was very clean and spacious. Staff were very nice and helpful. "
The price is $479
$584 total
includes taxes & fees
May 28 - May 29
Santa Maria Suites
View from property
Duval House
3.0 star property
9.4 out of 10, Exceptional, (1003)
"Everything looks good!"
The price is $159
$200 total
includes taxes & fees
May 12 - May 13
Duval House
Mansion Room #201 - Ocean View with private balcony - Adults Only | Terrace/patio
The Mansion on the Sea - Southernmost House in the USA
3.0 star property
9.2 out of 10, Wonderful, (1000)
"Excellent location, walk to everything "
The price is $499
$592 total
includes taxes & fees
May 12 - May 13
The Mansion on the Sea - Southernmost House in the USA
Outdoor pool
Silver Palms Inn
3.5 star property
9.2 out of 10, Wonderful, (1008)
"This property was great. Everything was very clean and quiet. The staff were amazing and very helpful in regards to any questions we had. It is also extremely close to duval street which was a plus. The only “downside” would be the area did get a little loud at night but that’s out of the control of the hotel. Overall I enjoyed this hotel and would love to stay here again in the future. "
The price is $197
$278 total
includes taxes & fees
May 14 - May 15
Silver Palms Inn
View from property
Oceans Edge Key West Resort, Hotel & Marina
4.0 star property
9.0 out of 10, Wonderful, (1521)
"Great staff & Customer service "
The price is $199
$283 total
includes taxes & fees
May 22 - May 23
Oceans Edge Key West Resort, Hotel & Marina
3 outdoor pools, pool umbrellas, sun loungers
The Marker Key West Harbor Resort
4.0 star property
8.8 out of 10, Excellent, (1003)
"Beautiful resort. Comfortable. Would stay again "
The price is $288
$383 total
includes taxes & fees
Jun 3 - Jun 4
The Marker Key West Harbor Resort
Exterior
Southwinds Motel
2.0 star property
8.8 out of 10, Excellent, (1004)
"This was a cute retro hotel. "
The price is $193
$240 total
includes taxes & fees
Jun 9 - Jun 10
Southwinds Motel
Courtyard
The Cabana Inn Key West - Adults Only
3.0 star property
8.8 out of 10, Excellent, (1004)
"Amazing staff, very helpful. Grounds were lovely, beautiful property in the heart of Duval St. historic district, a block off the action. Stayed in owner’s suite, nice large room, kitchen was lacking a bit in some basics, but ultimately we weren’t there long enough to really matter. We had a great stay, would highly recommend for charm and location. "
The price is $279
$359 total
includes taxes & fees
May 28 - May 29
The Cabana Inn Key West - Adults Only
Outdoor pool, pool umbrellas, sun loungers
The Reach Key West, Curio Collection by Hilton
4.0 star property
8.4 out of 10, Very Good, (615)
"There was an industrial size drill, drilling for hours at the beach right next door. Very loudly and not a great view from the beach chairs. Wished the Reach Resort would of discounted the room rates or at least compensated guests with a complimentary breakfast for the inconvenience of the noise. "
The price is $335
$438 total
includes taxes & fees
Jun 4 - Jun 5
The Reach Key West, Curio Collection by Hilton
Don't see what you're looking for?
See all available properties in Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular luxurious hotels

Most upscale stays in Key West in 2024

Frequently asked questions

Are you searching for the perfect hotel for your luxury getaway to Key West?
Known for its ocean views and sunsets, Key West also has some interesting things to see and do including Duval Street and Dry Tortugas National Park, so you may want to take in the local sights during your visit.
What's the best luxury place to stay in Key West?
Casa Marina Key West, Curio Collection by Hilton is a luxury resort with a private beach and a full-service spa, and it’s a popular choice for Expedia travelers looking for an elegant place to stay.
How many luxury hotels will I be able to find in Key West?
Lie in the lap of luxury during your getaway to Key West in one of Expedia’s 10 luxury hotels.
When can I expect good weather in Key West?
Planning for the weather is a good way to make your trip to Key West relaxing and enjoyable, especially when you’re splurging. The hottest months are usually August and July with an average temp of 84°F, while the coldest months are January and February with an average of 73°F. Average annual precipitation for Key West is 38 inches.
What's there to see and do in Key West?
Experience Key West with a stop at Duval Street, Dry Tortugas National Park, and Ernest Hemingway Home and Museum. If you have spare time during your trip, you might want to make a stop at Key West Lighthouse and Keeper’s Quarters Museum and Harry S. Truman Little White House.