Find 5 Star Hotels in Panama City from $87
Compare Panama City 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.
Explore similar 4-star hotels
Crowne Plaza Panama Airport, an IHG Hotel
There's nothing wrong with enjoying the finer things in life. Why not ask for the best during your trip to Panama City? There's no reason to delay a getaway to Panama City any longer. In fact, the sheer number of visitors to Panama City has shot up over the last year. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. What are you waiting for? Book one of Expedia's luxurious 5-star hotels in Panama City and get ready to enjoy the getaway of a lifetime.
5-Star Hotels in Panama City
You'll have a wonderful time at one of these 5-star hotels. Spa treatments, delicious meals, and personalized service are all at your fingertips. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready for a wonderful adventure. What kind of amenities will make your stay a wonderful one? A mud wrap treatment that will leave you feeling outstanding? 24-hour room service, so you can order that chocolate soufflé© in the wee hours of the morning? A deep-tissue massage to help your cares fall away?
Ready for experiences outside your hotel room? We hear you. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. Whatever you plan to do, the 5-star hotels in Panama City are waiting for you to rest up after an exciting day. Ready to learn more? Then check out our listings and pick the perfect accommodation for your needs.
Make Your Escape
The results are in, and Panama City 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. This is a great time to find 5-star hotel deals in @region! It's time to plan your next great escape. Opt for one of the 5-star hotels in Panama City today and decompress in total tranquility tomorrow.
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Panama City Hotels by Star Rating
Stay near popular Panama City attractions
- Albrook Shopping Mall
- Multiplaza Pacific Mall
- Amador Causeway
- Avenida Balboa
- Via Espana
- Cinta Costera
- El Dorado Mall
- Miraflores Locks
- Fuerte Amador Resort & Marina
- Iglesia del Carmen
- ATLAPA Conventions Center
- Uruguay Street
- Panama Viejo
- Amador Convention Center
- Multicentro Panama
- Los Pueblos Commercial Center
- Calle 50
- Metropolitan Cathedral of Panama
- Crown Casino
- Avenida Central
More Hotel Options in Panama City
- Beach Hotels (31)
- Business Hotels (97)
- Casinos (105)
- Cheap Hotels (56)
- Family Hotels (86)
- Historic Hotels (111)
- Honeymoon Resorts & Hotels (34)
- Hotel Wedding Venues (38)
- Hotel with a Concierge (62)
- Hotels & Resorts for Couples (49)
- Hotels with Air Conditioning (144)
- Hotels with Balconies (44)
- Hotels with Bars (93)
- Hotels with Childcare (20)
- Hotels with Connecting Rooms (28)
- Hotels with Free Breakfast (80)
- Hotels with Free Parking (110)
- Hotels with Free Wifi (136)
- Hotels with Hot Tubs (24)
- Hotels with Laundry Facilities (116)
- Hotels with Restaurants (131)
- Hotels with Room Service (91)
- Hotels with a Gym (60)
- Hotels with a Pool (88)
- Hotels with a View (74)
- Hotels with an Outdoor Pool (88)
- Hotels with smoking rooms (39)
- Luxury Hotels (48)
- Non-Smoking Hotels (80)
- Pet-friendly Hotels (24)
- Resorts & Hotels with Spas (45)
- Romantic Hotels (20)
More Accommodation Types in Panama City
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- Vacation Homes in Panama City (50)
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- B&B in Panama City (13)
- Guest Houses in Panama City (5)
- Lodges in Panama City (5)
- Villas in Panama City (3)
- Resorts in Panama City (2)
- Castles in Panama City (1)
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Explore more hotels
- W Panama
- Marriott Panama Hotel
- TRYP by Wyndham Panamá Centro
- Hospedium Princess Hotel Panama
- Sheraton Grand Panama
- Hilton Panama
- Holiday Inn Panama Distrito Financiero, an IHG Hotel
- Hotel Ojos del Rio
- Sofitel Legend Casco Viejo, Panama City
- Riande Urban Hotel
- Radisson Hotel Panama Canal
- AC Hotel by Marriott Panama City
- The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
- MARINN PLACE Financial District
- Central Hotel Panama Casco Viejo
- Residence Inn by Marriott Panama City
- Sortis Hotel, Spa & Casino, Autograph Collection
- The Executive Hotel
- Hotel El Panama by Faranda Grand, a member of Radisson Individuals
- Hotel La Compania, in the Unbound Collection by Hyatt