A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.

Panama City Vacation Rentals

Check prices for these dates

In two weeks
Oct 30 - Nov 1
In two months
Dec 11 - Dec 13
In three months
Jan 8 - Jan 10
In four months
Feb 5 - Feb 7

Our top choices for Panama City vacation rentals

A spacious indoor courtyard with tiled flooring, multiple seating areas, and hanging plants.

1. La Isabela Suites

La Isabela Suites
3.5 star property
Casco Viejo
10.0 out of 10, Exceptional, (212 reviews)
"Location in old town, across from Plaza Simon Bolivar, is the perfect place to venture around old town and the new city. Great restaurants and shops within easy walking distance. I relied on recommendations from the staff for a couple of things and their selections exceeded my expectations. Highly recommend staying if visiting Panama City."
United States
David
$143 nightly
The price is $159
Oct 18 - Oct 19
Total with taxes and fees
La Isabela Suites
A modern indoor pool area with clear blue water, lounge chairs, and a wall of plants.

2. Casco View Life Residences

Casco View Life Residences
4.0 star property
Santa Ana
9.0 out of 10, Wonderful, (112 reviews)
"It is a new place, an apartment was in pristine condition. The building is 2 blocks away from the old town."
United States
Arshak Andrew
$111 nightly
The price is $122
Oct 16 - Oct 17
Total with taxes and fees
Casco View Life Residences
A multi-story building with balconies, large windows, and a clear blue sky.

3. Las Clementinas

Las Clementinas
3.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (206 reviews)
"Great food and location"
United States
James
$146 nightly
The price is $161
Oct 28 - Oct 29
Total with taxes and fees
Las Clementinas
A modern hotel lobby with a marble staircase, seating areas, and a large mirror reflecting the space.

4. Torres de Alba Hotel & Suites

Torres de Alba Hotel & Suites
3.5 star property
Bella Vista
8.8 out of 10, Excellent, (590 reviews)
"Good stay here. Breakfast buffet was limited but good. Staff very friendly and helpful."
United States
Nalisa
$92 nightly
The price is $102
Oct 16 - Oct 17
Total with taxes and fees
Torres de Alba Hotel & Suites
A rooftop pool with a city view, lounge chairs, and a clear sky.

5. Corporate Stays Arcadia | Executive Furnished Apartments

Corporate Stays Arcadia | Executive Furnished Apartments
4.0 star property
Costa del Este
9.2 out of 10, Wonderful, (401 reviews)
"Everything was nice"
United States
Gloria
$92 nightly
The price is $101
Nov 15 - Nov 16
Total with taxes and fees
Corporate Stays Arcadia | Executive Furnished Apartments
A modern building with a sign reading "LA RESIDENCE" and a car parked in front.

6. La Résidence Panamá

La Résidence Panamá
3.5 star property
Bella Vista
9.2 out of 10, Wonderful, (21 reviews)
"Excellent rooms and fantastic staff!"
United States
Mohamad
$123 nightly
The price is $138
Oct 16 - Oct 17
Total with taxes and fees
La Résidence Panamá
A rooftop pool with lounge chairs and a cityscape view.

7. Marriott Executive Apartments Panama City, Finisterre

Marriott Executive Apartments Panama City, Finisterre
4.0 star property
Bella Vista
8.8 out of 10, Excellent, (775 reviews)
"The staff were very friendly and made my birthday trip so special! Top-tier experience"
United States
Bruce
$118 nightly
The price is $130
Oct 31 - Nov 1
Total with taxes and fees
Marriott Executive Apartments Panama City, Finisterre
A rooftop infinity pool with a city skyline view, lounge chairs, and palm trees.

8. Apartments at The Sands – Ocean View Panama City

Apartments at The Sands – Ocean View Panama City
3.5 star property
Calidonia
7.8 out of 10, Good, (29 reviews)
"Check in at 3 was a bit difficult, but the assistance staff were wonderful. Would absolutely stay again."
United States
Thomas M
$59 nightly
The price is $64
Oct 17 - Oct 18
Total with taxes and fees
Apartments at The Sands – Ocean View Panama City
A modern living room with a sofa, a TV, a small table, and a balcony with a view of the city.

9. Living 73 Panamá by Boutique Apartments

Living 73 Panamá by Boutique Apartments
3.0 star property
San Francisco
9.0 out of 10, Wonderful, (2 reviews)
"Perfect"
United States
Lorenz
$170 nightly
The price is $203
Nov 1 - Nov 2
Total with taxes and fees
Living 73 Panamá by Boutique Apartments
A rooftop pool area with lounge chairs and a table, overlooking a cityscape with tall buildings.

10. Boutique Apartments Panama

Boutique Apartments Panama
3.5 star property
Bella Vista
8.0 out of 10, Very good, (395 reviews)
"Great stay!!!!"
United States
fitz
$146 nightly
The price is $160
Oct 18 - Oct 19
Total with taxes and fees
Boutique Apartments Panama
A modern hotel entrance with a well-lit facade, a prominent sign, and a landscaped garden area.

11. Yoo Panamá by Boutique Apartments

Yoo Panamá by Boutique Apartments
3.5 star property
Bella Vista
8.0 out of 10, Very good, (144 reviews)
"It was a very beautiful property and prime location! All around experience was great!"
United States
Michelle
$186 nightly
The price is $191
Nov 15 - Nov 16
Total with taxes and fees
Yoo Panamá by Boutique Apartments
A rooftop pool with lounge chairs, a city skyline view, and a high-rise building in the background.

12. OCEAN VIEW - STUDIO APARTMENT

OCEAN VIEW - STUDIO APARTMENT
Calidonia
9.4 out of 10, Exceptional, (25 reviews)
"Great location, good communication and nice, safe accomodation"
United States
Michele T.
$130 nightly
The price is $139
Oct 16 - Oct 17
Total with taxes and fees
OCEAN VIEW - STUDIO APARTMENT
A swimming pool with lounge chairs, surrounded by greenery and modern buildings.

13. Cozy Urban Loft 1br Near Coast

Cozy Urban Loft 1br Near Coast
2.0 star property
San Francisco
$139 nightly
The price is $153
Oct 16 - Oct 17
Total with taxes and fees
Cozy Urban Loft 1br Near Coast
A tall, modern skyscraper with a grid-like facade and numerous windows.

14. Luxury City View Apartments at Worldwide

Luxury City View Apartments at Worldwide
3.0 star property
Bella Vista
10.0 out of 10, Exceptional, (2 reviews)
"I had a wonderful stay at this property The property was exceptionally clean, and the staff went above and beyond to make sure I felt welcome. Early check in. Highly recommended."
United States
Andre
$48 nightly
The price is $53
Oct 16 - Oct 17
Total with taxes and fees
Luxury City View Apartments at Worldwide
A playground with slides and climbing structures, surrounded by a fenced area with a view of tall buildings.

15. The Hub by Boutique Apartments

The Hub by Boutique Apartments
3.0 star property
San Francisco
$172 nightly
The price is $176
Oct 20 - Oct 21
Total with taxes and fees
The Hub by Boutique Apartments
A modern living room with a sofa, coffee table, and chairs, a dining table with water bottles, and large windows with a city view.

16. Mini Design By Wynwood House

Mini Design By Wynwood House
3.0 star property
Bella Vista
10.0 out of 10, Exceptional, (4 reviews)
"The pool is amazing. I love that is it long enough to do laps if one would like a workout."
United States
Monica
$141 nightly
The price is $155
Oct 18 - Oct 19
Total with taxes and fees
Mini Design By Wynwood House
An outdoor seating area with tables and chairs, a tree with pink blossoms, and a cityscape view.

17. Modern Design Apartments near Sortis

Modern Design Apartments near Sortis
4.0 star property
Bella Vista
9.0 out of 10, Wonderful, (11 reviews)
"This property was much more than I expected, room and property was clean, lots of restaurants around the area, easy to get around, will certainly be back at this property"
United States
Kareem
$63 nightly
The price is $69
Oct 21 - Oct 22
Total with taxes and fees
Modern Design Apartments near Sortis
A rooftop pool with lounge chairs and a bar, overlooking a city skyline at dusk.

18. Yoo Panama Luxury Ocean View Apartment

Yoo Panama Luxury Ocean View Apartment
3.5 star property
Bella Vista
8.4 out of 10, Very good, (6 reviews)
"Good price for the location."
United States
Mark
$124 nightly
The price is $136
Oct 19 - Oct 20
Total with taxes and fees
Yoo Panama Luxury Ocean View Apartment
Photo of the whole room

19. w* | Refined 1BR in Casco Antiguo

w* | Refined 1BR in Casco Antiguo
Casco Viejo
9.2 out of 10, Wonderful, (7 reviews)
"It’s very good for solo traveler. Juan is a great host and responds very quickly. Great location in the old city."
United States
Dongmei
$80 nightly
The price is $80
Oct 18 - Oct 19
Total with taxes and fees
w* | Refined 1BR in Casco Antiguo
A modern hotel room with a large bed, bedside tables with lamps, and artwork on the walls.

20. La Palma Experience

La Palma Experience
3.0 star property
Amador
8.2 out of 10, Very good, (14 reviews)
"I would recommend this hotel. It has a great location and offers a very pleasant experience."
United States
Juan Luis Perez
$68 nightly
The price is $76
Oct 18 - Oct 19
Total with taxes and fees
La Palma Experience
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Panama City Hotel Reviews

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

10/10 Excellent
"Beautiful historic hotel located in the prime Plaza independencia just across from the Cathedral in Casco Viejo. Wonderful staff, nice breakfasts, Live music in the lobby…just wonderful. I will look forward to my return."
Robert 2-night trip
Posted 1 hour ago
Central Hotel Panama Casco Viejo

Find out more about Panama City

Everything you need to know about Panama City vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Panama City vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Panama City vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Panama City vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Panama City. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Panama City in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $53 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Panama City rentals

At Expedia, we put the best Panama City vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Panama City rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Panama City vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Panama City. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Can I find vacation rentals in Panama City?

Yes, we give you a choice of vacation rentals in Panama City near Panama Canal Railway, or you can choose a more remote option if you're looking for a relaxing stay. Tourists like the array of shops and top-notch restaurants in Panama City. While you're in the area, grab a bite or have a drink at the lively bars and cafes.

What's the top vacation rental in Panama City?

Downtown Villa with Private Pool & Bar: This Panama City vacation home rental offers an outdoor pool, a patio, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 8 bedrooms as well as a kitchen with a fridge, a stovetop, and kitchenware, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a garden. Some other top choices in Panama City are Casa Randa: 6 Ensuite Bedrooms near the Panama Canal and Two Floors Duplex in the middle of Panama City..

How many vacation rentals are there in Panama City?

With 59 Expedia vacation rentals, you're sure to find just the right place for your Panama City stay.

What can I see and do in Panama City?

Cultural attractions include National Theater and Interoceanic Canal Museum, whereas Cinta Costera and Miraflores Locks are a couple of picturesque spots to enjoy the outdoors. Albrook Shopping Mall and Via Espana are other places to visit while you're in town.

What are vacation rentals like in Panama City?

Vacation rentals are privately owned accommodations you can stay in for several days or longer in Panama City. Vacation rentals offer amenities like kitchens and laundry facilities so you'll feel just like you're at home. If you're concerned about cleanliness, vacation rentals can provide a sense of safety away from public hotel elevators and busy lobbies while still allowing you to travel. You'll also find more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a popular option for families.