A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.

Panama City Vacation Rentals

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Our top choices for Panama City vacation rentals

Corporate Stays Arcadia | Executive Furnished Apartments

Corporate Stays Arcadia | Executive Furnished Apartments
4.0 star property
Costa del Este
9.2 out of 10, Wonderful, (318 reviews)
"This is a great stay , property is very quiet and peaceful highly recommend"
United States
kenron
$98 nightly
The price is $109
Aug 13 - Aug 14
Total with taxes and fees
Corporate Stays Arcadia | Executive Furnished Apartments

Dovle Residences by HMS-Preferred Member

Dovle Residences by HMS-Preferred Member
3.5 star property
San Francisco
8.4 out of 10, Very Good, (16 reviews)
"Great stay. Friendly staff"
Canada
Ani
$147 nightly
The price is $162
Jul 19 - Jul 20
Total with taxes and fees
Dovle Residences by HMS-Preferred Member

Modern Design Apartments near Sortis

Modern Design Apartments near Sortis
4.0 star property
Bella Vista
8.8 out of 10, Excellent, (3 reviews)
"Apartamento magnífico. Muy bien equipado. Con piscina, gimnasio y roof top en el edificio. Limpio, moderno, confortable, funcional. 100% recomendable"
Spain
Alvaro
$57 nightly
The price is $63
Jul 23 - Jul 24
Total with taxes and fees
Modern Design Apartments near Sortis

Yoo Panama Luxury Ocean View Apartment

Yoo Panama Luxury Ocean View Apartment
3.5 star property
Bella Vista
10.0 out of 10, Exceptional, (2 reviews)
"Amazing. Right next to Hilton on balboa."
United States
Abdullah
$100 nightly
The price is $111
Aug 10 - Aug 11
Total with taxes and fees
Yoo Panama Luxury Ocean View Apartment

La Isabela Suites

La Isabela Suites
3.5 star property
Casco Viejo
9.8 out of 10, Exceptional, (206 reviews)
"A very helpful and friendly staff with quiet rooms that were larger than we expected. The decor was lovely and well maintained."
United States
Gabriela
$156 nightly
The price is $172
Jul 17 - Jul 18
Total with taxes and fees
La Isabela Suites

Modern Apartments at The Gray Prime Location

Modern Apartments at The Gray Prime Location
4.0 star property
Bella Vista
9.0 out of 10, Wonderful, (2 reviews)
"Close to attractions and great restaurants"
United States
Tiyania
$71 nightly
The price is $78
Jul 17 - Jul 18
Total with taxes and fees
Modern Apartments at The Gray Prime Location

Apartments at The Sands – Ocean View Panama City

Apartments at The Sands – Ocean View Panama City
3.5 star property
Calidonia
8.0 out of 10, Very Good, (12 reviews)
"Excellent location, Great rooftop restaurant, bar and entertainment/activities. Walking distance to public exercise facilities, a seafood market, local cuisine. The bus and metro station is also walking distance behind the property."
United States
Dillon
$68 nightly
The price is $74
Jul 20 - Jul 21
Total with taxes and fees
Apartments at The Sands – Ocean View Panama City

Las Clementinas

Las Clementinas
3.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (198 reviews)
"Great food and location"
United States
James
$159 nightly
The price is $175
Jul 26 - Jul 27
Total with taxes and fees
Las Clementinas

La Résidence Panamá

La Résidence Panamá
2.5 star property
Bella Vista
9.2 out of 10, Wonderful, (19 reviews)
"Excellent rooms and fantastic staff!"
United States
Mohamad
$147 nightly
The price is $162
Jul 17 - Jul 18
Total with taxes and fees
La Résidence Panamá

Modern Apartments at the Hub City views

Modern Apartments at the Hub City views
3.0 star property
San Francisco
$105 nightly
The price is $115
Jul 20 - Jul 21
Total with taxes and fees
Modern Apartments at the Hub City views

Yoo Panamá by Boutique Apartments

Yoo Panamá by Boutique Apartments
3.5 star property
Bella Vista
7.8 out of 10, Good, (107 reviews)
"Very clean room, highly upgraded re-modeled unit. Excellent balcony with view from city to Casco Viejo (Old Town). Washing Machine & Dryer. Nice TV’s and quality internet. Great water pressure and plenty of hot water. Highly recommend!"
United States
John
$196 nightly
The price is $202
Aug 9 - Aug 10
Total with taxes and fees
Yoo Panamá by Boutique Apartments

San Francisco by Wynwood House

San Francisco by Wynwood House
3.0 star property
San Francisco
9.2 out of 10, Wonderful, (57 reviews)
"Clean and walkable location"
United States
Tamera
$147 nightly
The price is $160
Jul 21 - Jul 22
Total with taxes and fees
San Francisco by Wynwood House

Casco View Apartments

Casco View Apartments
3.5 star property
Santa Ana
9.0 out of 10, Wonderful, (100 reviews)
"Always an amazing stay"
United States
chris
$107 nightly
The price is $118
Jul 29 - Jul 30
Total with taxes and fees
Casco View Apartments

Boutique Apartments Panamá Coco del Mar

Boutique Apartments Panamá Coco del Mar
3.5 star property
San Francisco
7.6 out of 10, Good, (205 reviews)
"Host was very good at responding to any questions we had to make the most of our stay!!"
United States
Katrina
$189 nightly
The price is $208
Aug 16 - Aug 17
Total with taxes and fees
Boutique Apartments Panamá Coco del Mar

La Palma Experience

La Palma Experience
3.0 star property
Amador
8.4 out of 10, Very Good, (8 reviews)
"Air conditioner has good working. People are nice and good response for us. Basically room are clean but I can see small ants some of them on the table and on floor. I doesn't matter for it. In neighbor restaurant made big sounds at night to midnight."
Japan
Shuntaro
$57 nightly
The price is $63
Aug 13 - Aug 14
Total with taxes and fees
La Palma Experience

Modern Apartments PH Living 73 SF

Modern Apartments PH Living 73 SF
3.5 star property
San Francisco
10.0 out of 10, Exceptional, (1 review)
"To the owner, it would help if the top sheet is larger than the bed, difficult for two people to cover themselves"
United States
Dawid
$89 nightly
The price is $98
Jul 29 - Jul 30
Total with taxes and fees
Modern Apartments PH Living 73 SF

Casa Love by Wynwood House

Casa Love by Wynwood House
3.0 star property
Casco Viejo
8.8 out of 10, Excellent, (26 reviews)
"Spotless, well appointed and very nice responsive customer support- I would definitely stay there again"
United States
laura
$107 nightly
The price is $118
Jul 19 - Jul 20
Total with taxes and fees
Casa Love by Wynwood House

Marriott Executive Apartments Panama City, Finisterre

Marriott Executive Apartments Panama City, Finisterre
4.0 star property
Bella Vista
8.8 out of 10, Excellent, (725 reviews)
"Staff and property was excellent."
United States
Robyn
$118 nightly
The price is $130
Aug 15 - Aug 16
Total with taxes and fees
Marriott Executive Apartments Panama City, Finisterre

Mini Design By Wynwood House

Mini Design By Wynwood House
3.0 star property
Bella Vista
10.0 out of 10, Exceptional, (3 reviews)
"The pool is amazing. I love that is it long enough to do laps if one would like a workout."
United States
Monica
$183 nightly
The price is $201
Jul 19 - Jul 20
Total with taxes and fees
Mini Design By Wynwood House

Apex Executive Apartments - Dovle

Apex Executive Apartments - Dovle
2.0 star property
Parque Lefevre
$155 nightly
The price is $171
Aug 13 - Aug 14
Total with taxes and fees
Apex Executive Apartments - Dovle
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Panama City Hotel Reviews

Find out more about Panama City

Everything you need to know about Panama City vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Panama City vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Panama City vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Panama City vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Panama City. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Panama City in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $63 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Panama City rentals

At Expedia, we put the best Panama City vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Panama City rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Panama City vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Panama City. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Can I find vacation rentals in Panama City?

Yes, we give you a choice of vacation rentals in Panama City near Panama Canal Railway, or you can choose a more remote option if you're looking for a relaxing stay. Tourists like the array of shops and top-notch restaurants in Panama City. While you're in the area, grab a bite or have a drink at the lively bars and cafes.

What's the top vacation rental in Panama City?

Tropical House with Historic Charm, WiFi, Private Bathrooms and Workspaces: This Panama City vacation home rental offers a balcony, a selection of games, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 6 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. Some other top choices in Panama City are Two Floors Duplex in the middle of Panama City. and Breathtaking Views Mansion w/King Beds.

How many vacation rentals are there in Panama City?

With 58 Expedia vacation rentals, you're sure to find just the right place for your Panama City stay.

What can I see and do in Panama City?

Cultural attractions include National Theater and Interoceanic Canal Museum, whereas Cinta Costera and Miraflores Locks are a couple of picturesque spots to enjoy the outdoors. Albrook Shopping Mall and Via Espana are other places to visit while you're in town.

What are vacation rentals like in Panama City?

Vacation rentals are privately owned accommodations you can stay in for several days or longer in Panama City. Vacation rentals offer amenities like kitchens and laundry facilities so you'll feel just like you're at home. If you're concerned about cleanliness, vacation rentals can provide a sense of safety away from public hotel elevators and busy lobbies while still allowing you to travel. You'll also find more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a popular option for families.