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Find hotels in Southeast Missouri, MO from $52

Check Southeast Missouri hotel prices

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May 22 - May 23
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May 23 - May 24
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May 24 - May 26
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May 31 - Jun 2

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Compare 569 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Courtyard
Hampton Inn Cape Girardeau I 55 East
2.5 star property
9.6 out of 10, Exceptional, (622)
"Excellent hotel, bed was comfortable and the room was spacious with a small couch and desk area."
The price is $114
$128 total
includes taxes & fees
Jun 2 - Jun 3
Hampton Inn Cape Girardeau I 55 East
Lobby
Drury Inn & Suites Jackson MO
3.0 star property
9.6 out of 10, Exceptional, (960)
"Safety is everything to me when traveling with my family and I felt just that, safe."
The price is $108
$114 total
includes taxes & fees
May 27 - May 28
Drury Inn & Suites Jackson MO
Lobby
Drury Inn & Suites Cape Girardeau
3.0 star property
9.4 out of 10, Exceptional, (784)
"Everyone was very friendly and the breakfast provided was amazing!! "
The price is $108
$122 total
includes taxes & fees
May 27 - May 28
Drury Inn & Suites Cape Girardeau
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Property amenity
Drury Inn & Suites Sikeston, MO
3.0 star property
9.4 out of 10, Exceptional, (1000)
"Convenient location and newer facility compared to other area options."
The price is $108
$123 total
includes taxes & fees
Jun 2 - Jun 3
Drury Inn & Suites Sikeston, MO
Lobby
Pear Tree Inn Sikeston
2.5 star property
9.4 out of 10, Exceptional, (1001)
"Just a rest stop"
The price is $94
$108 total
includes taxes & fees
May 28 - May 29
Pear Tree Inn Sikeston
Lobby lounge
Fairfield Inn & Suites by Marriott Poplar Bluff
2.5 star property
9.4 out of 10, Exceptional, (584)
"Had a great stay"
The price is $107
$121 total
includes taxes & fees
Jun 2 - Jun 3
Fairfield Inn & Suites by Marriott Poplar Bluff
Property amenity
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS, an IHG Hotel
2.5 star property
9.4 out of 10, Exceptional, (556)
"Friendly and clean"
The price is $122
$140 total
includes taxes & fees
May 27 - May 28
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS, an IHG Hotel
Exterior
Holiday Inn Club Vacations Timber Creek Resort at De Soto, an IHG Hotel
3.5 star property
9.4 out of 10, Exceptional, (126)
"When we walked in the lodge it was spotless. Very homey and clean. The staff was so kind. We will definitely be back."
The price is $143
$163 total
includes taxes & fees
Jun 13 - Jun 14
Holiday Inn Club Vacations Timber Creek Resort at De Soto, an IHG Hotel
Lobby
Drury Inn & Suites Poplar Bluff
3.0 star property
9.2 out of 10, Wonderful, (707)
"The only thing that I was disappointed with is that I did not get my rewards as a Gold Key Member!"
The price is $103
$117 total
includes taxes & fees
Jun 2 - Jun 3
Drury Inn & Suites Poplar Bluff
Fridge, microwave, coffee/tea maker
Shepherd Mountain Inn
2.5 star property
9.2 out of 10, Wonderful, (211)
"Convenient "
The price is $115
$126 total
includes taxes & fees
Jun 2 - Jun 3
Shepherd Mountain Inn
Lobby
Pear Tree Inn Cape Girardeau West
2.5 star property
9.0 out of 10, Wonderful, (1001)
"We did not like the pillows. They were uncomfortable and did not conform to the shape of a person's head/neck."
The price is $66
$74 total
includes taxes & fees
Jun 2 - Jun 3
Pear Tree Inn Cape Girardeau West
Reception
The Farmstead Hotel
2.5 star property
9.0 out of 10, Wonderful, (193)
"Great location. Very well maintained."
The price is $98
$112 total
includes taxes & fees
Jun 2 - Jun 3
The Farmstead Hotel
Exterior
Hampton Inn Farmington
2.5 star property
9.0 out of 10, Wonderful, (437)
"They were extremely busy at breakfast and was continually out of food and took a long time to get it refilled."
The price is $150
$170 total
includes taxes & fees
Jun 20 - Jun 21
Hampton Inn Farmington
BBQ/picnic area
Auburn Place Hotel And Suites
2.5 star property
8.8 out of 10, Excellent, (1001)
"Unusual courtyard view fro rooms. Nice indoor pool. Quick friendly check in."
The price is $66
$75 total
includes taxes & fees
Jun 11 - Jun 12
Auburn Place Hotel And Suites
Room, 2 Queen Beds, Non Smoking | Premium bedding, individually furnished, desk, laptop workspace
Microtel Inn & Suites by Wyndham Sainte Genevieve
2.5 star property
8.8 out of 10, Excellent, (490)
"Comfortable clean place to stay for the night"
The price is $79
$88 total
includes taxes & fees
May 23 - May 24
Microtel Inn & Suites by Wyndham Sainte Genevieve
Fountain
Bullwinkles Rustic Lodge
2.5 star property
8.8 out of 10, Excellent, (152)
"everything was perfect"
The price is $84
$95 total
includes taxes & fees
Jun 16 - Jun 17
Bullwinkles Rustic Lodge
Lobby
Comfort Inn Sullivan
2.5 star property
8.8 out of 10, Excellent, (620)
"Clean and comfortable "
The price is $120
$131 total
includes taxes & fees
Jun 2 - Jun 3
Comfort Inn Sullivan
Front of property
Honeysuckle Inn - Mountain View
3.0 star property
8.6 out of 10, Excellent, (190)
"Exterior of the building was a neat design. Interior of the room so what dated, but generally clean."
The price is $111
$120 total
includes taxes & fees
May 23 - May 24
Honeysuckle Inn - Mountain View
Hallway
Travel Inn & Suites
2.5 star property
8.4 out of 10, Very Good, (523)
"Easy check in, clean quiet room."
The price is $58
$66 total
includes taxes & fees
Jun 2 - Jun 3
Travel Inn & Suites
Exterior
Candlewood Suites Cape Girardeau, an IHG Hotel
2.5 star property
8.2 out of 10, Very Good, (624)
"Per friendly "
The price is $88
$104 total
includes taxes & fees
May 26 - May 27
Candlewood Suites Cape Girardeau, an IHG Hotel
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See all available properties in Southeast Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More cheap stays in Southeast Missouri

Auburn Place Hotel And Suites

Auburn Place Hotel And Suites

3265 William St, Cape Girardeau, MO
The price is $66 per night from Jun 11 to Jun 12
$66
$75 total
includes taxes & fees
Jun 11 - Jun 12
8.6/10 Excellent! (1,006 reviews)

Stay near popular Southeast Missouri attractions

Image for Meramec Caverns

Meramec Caverns

Explore the great outdoors at Meramec Caverns, a lovely green space in Sullivan. While in this family-friendly area, you can enjoy the coffeehouses.

See properties
Meramec Caverns

Recent reviews of Southeast Missouri hotels
Expedia verified reviews

Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

5/5 Excellent
Good for those on a budget.
"Nice place to stay. Good for those on a budget. Basic room. Everything worked. Fairly new property. Have stayed at property several times. Easy access to main roads"
A verified traveler stayed at Motel 6 Poplar Bluff, MO
Posted 1 day ago
Motel 6 Poplar Bluff, MO