Title: The Best 5 Star Hotels in Drepano from $85 | Expedia.com [Drepano Travel Guide](https://expedia.com/Drepano.dx6053713)[Hotels in Drepano](https://expedia.com/Drepano-Hotels.d6053713.Travel-Guide-Hotels)[Vacation Rentals in Drepano](https://expedia.com/Drepano-Vacation-Rentals.d6053713.Travel-Guide-VacationRentals)[Flights to Drepano](https://expedia.com/Cheap-Flights-To-Drepano.d6053713.Travel-Guide-Flights)[Car Rentals in Drepano](https://expedia.com/Car-Rentals-In-Drepano.d6053713.Car-Rental-Guide)[Drepano Vacation Packages](https://expedia.com/Drepano.d6053713.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Drepano 5 Star Hotels Tonight [Feb 5 - Feb 6](https://www.expedia.com/Hotel-Search?regionId=6053713&startDate=2026-02-05&endDate=2026-02-06&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 6 - Feb 7](https://www.expedia.com/Hotel-Search?regionId=6053713&startDate=2026-02-06&endDate=2026-02-07&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Feb 6 - Feb 8](https://www.expedia.com/Hotel-Search?regionId=6053713&startDate=2026-02-06&endDate=2026-02-08&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 13 - Feb 15](https://www.expedia.com/Hotel-Search?regionId=6053713&startDate=2026-02-13&endDate=2026-02-15&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Drepano 5-star hotels ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1060000/1058600/1058576/c9df07c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/2000000/1060000/1058600/1058576/75f915b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Suite, Sea View | Minibar, in-room safe, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1060000/1058600/1058576/13d07fe8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Minibar, in-room safe, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1060000/1058600/1058576/4f72a0f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Amphitryon Hotel [](https://www.expedia.com/Nafplio-Hotels-Amphitryon-Hotel.h1058576.Hotel-Information) Nafplio City Centre 8.6/10 Excellent (180 reviews) "Great hotel,great food,great view. Friendly staff. Great location We will definitely stay there again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John $203 nightly $236 total Feb 13 - Feb 14 Total with taxes and fees [](https://www.expedia.com/Nafplio-Hotels-Amphitryon-Hotel.h1058576.Hotel-Information) ![Private beach, beach bar](https://images.trvl-media.com/lodging/106000000/105780000/105779800/105779734/14cc1110.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/106000000/105780000/105779800/105779734/16caf5f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/106000000/105780000/105779800/105779734/52bd413c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/106000000/105780000/105779800/105779734/495af458.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SEAFOS Luxury Resort & Spa - Limited Edition by Leonardo Hotels [](https://www.expedia.com/Nafplio-Hotels-SEAFOS-Luxury-Resort-Spa.h105779734.Hotel-Information) Nafplio 7.6/10 Good (14 reviews) "It was a lovely location for a resort." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John [](https://www.expedia.com/Nafplio-Hotels-SEAFOS-Luxury-Resort-Spa.h105779734.Hotel-Information) ![Villa, 2 Bedrooms, Private Pool, Sea View (Palace) | Minibar, in-room safe, desk, soundproofing](https://images.trvl-media.com/lodging/2000000/1220000/1218100/1218018/bd30549f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch and dinner served, ocean views ](https://images.trvl-media.com/lodging/2000000/1220000/1218100/1218018/7064f92f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1220000/1218100/1218018/f0f9ce10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Villa, 1 Bedroom, Private Pool, Sea View (Ambassador) | View from room](https://images.trvl-media.com/lodging/2000000/1220000/1218100/1218018/88db8679.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Nafplia Palace Hotel & Villas [](https://www.expedia.com/Nafplio-Hotels-Nafplia-Palace-Hotel-Villas.h1218018.Hotel-Information) Nafplio City Centre 8.2/10 Very Good (208 reviews) "Great location, stunning view, adorable staff" ![France](https://a.travel-assets.com/egds/marks/flags/fr.svg) robert [](https://www.expedia.com/Nafplio-Hotels-Nafplia-Palace-Hotel-Villas.h1218018.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Drepano-Hotels.s50-0-d6053713.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Drepano-Hotels.s50-0-d6053713.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Drepano. ![Naus Hotel](https://images.trvl-media.com/lodging/108000000/107180000/107172400/107172330/f37a7455_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Naus Hotel Vironos Nafplio $93 nightly $109 total Feb 25 - Feb 26 Total with taxes and fees 9.4/10 Exceptional! (55 reviews) [](https://expedia.com/Naus-Hotel.h107172330.Hotel-Information) ![Nafsimedon Hotel](https://images.trvl-media.com/lodging/7000000/6440000/6430700/6430681/37dca5e8_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Nafsimedon Hotel Sideras Merarxias 9 Nafplio Peloponnese $71 nightly $85 total Feb 27 - Feb 28 Total with taxes and fees 9.2/10 Wonderful! (136 reviews) [](https://expedia.com/Nafplio-Hotels-Nafsimedon-Hotel.h6430681.Hotel-Information) ![Amalia Hotel Nafplio](https://images.trvl-media.com/lodging/4000000/3080000/3070500/3070413/fe09b860_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Amalia Hotel Nafplio Amalias Street Nafplio Peloponnese $109 nightly $128 total Feb 19 - Feb 20 Total with taxes and fees 9/10 Wonderful! (606 reviews) [](https://expedia.com/Nafplio-Hotels-Amalia-Hotel-Nafplio.h3070413.Hotel-Information) Still don't see what you're looking for? [See all properties in Drepano.](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F6%2F2026&endDate=2%2F7%2F2026®ionId=6053713&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F6%2F2026&endDate=2%2F7%2F2026®ionId=6053713&star=50&star=50&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F6%2F2026&endDate=2%2F7%2F2026®ionId=6053713&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F6%2F2026&endDate=2%2F7%2F2026®ionId=6053713&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F6%2F2026&endDate=2%2F7%2F2026®ionId=6053713&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F6%2F2026&endDate=2%2F7%2F2026®ionId=6053713&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Top Drepano Hotel Reviews ![SEAFOS Luxury Resort & Spa - Limited Edition by Leonardo Hotels](https://images.trvl-media.com/lodging/106000000/105780000/105779800/105779734/f6a3a98f_y.jpg) ### SEAFOS Luxury Resort & Spa - Limited Edition by Leonardo Hotels 10/10 Excellent "Great location with easy access to beach and many local gems such as Kondyli, Nauplion, Tolo, and Mikines. Property is in great condition with very friendly staff. Maria, Xristos, and Fotis were amazing. Had super good breakfast and lunch with many good choices and excellent quality local ingredients. Housekeeping was very attentive and kept the rooms extremely clean. The only issue I found was the amount of staff at pool restaurant but that was not enough to impact my overall experience as it was offset by tranquility. I saw many comments about mosquitos but i had no issues at all in July. Thank you Seafos and hope to be book soon. " [](https://expedia.com/Nafplio-Hotels-SEAFOS-Luxury-Resort-Spa.h105779734.Hotel-Information) ## Find out more about Drepano Ready to experience the next standard in luxury? We know you are thinking about it. Add an extra layer of luxury on your next trip to Drepano by treating yourself to the best of the best when it comes to accommodation. It's an ideal combination. There's no reason to delay a getaway to Drepano any longer. You'll join the multitudes of vacationers who have made Drepano so fashionable recently. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. What are you waiting for? Reserve one of our 5-star hotels in Drepano and indulge in the finer things in life for a while. ### Get a Great Deal on 5-Star Hotels in Drepano You'll have a wonderful time at one of these 5-star hotels. Michelin-starred restaurants, excellent customer care, and rejuvenating spa offerings are waiting for you. You're sure to find exactly the accommodation you need. You'll also enjoy a high standard of care and meticulous guest relations, so get ready for a wonderful adventure. What kind of amenities will make your stay a wonderful one? A full-body massage to help your cares fall away? A concierge to help you pick out your next adventure? Plush carpeting, piping hot coffees, and even a hot tub in the bathroom...these hotels will astonish you. Don't want to take our word for it? Explore our listings and pick the perfect accommodation for your needs. Can't wait to get outside? We've got you covered. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. Whatever you plan to do, the 5-star hotels in Drepano are waiting for you to rest up after an exciting day. ### Your Getaway Starts Today The results are in, and Drepano 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Expedia can help you land a great deal on accommodation. It's time to plan your next great escape. Select one of our Drepano 5-star hotels today and settle down in total tranquility tomorrow. ## Frequently asked questions ### What are the best 5-star hotels in Drepano? ### How much does it cost to stay in a 5-star hotel in Drepano? > - Search for the lowest price per night from $85 ### What makes a hotel 5 stars in Drepano? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [Hotels near Plaka Beach ](https://www.expedia.com/Plaka-Beach-Hotels.0-l6334185-0.Travel-Guide-Filter-Hotels) - [Vivari Hotels ](https://www.expedia.com/Vivari-Hotels.d6272979.Travel-Guide-Hotels) - [Vacation Homes in Vivari ](https://www.expedia.com/Vivari-Private-Vacation-Homes.d6272979-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Family Hotels in Vivari ](https://www.expedia.com/Vivari-Hotels-Family-Hotel.0-0-d6272979-tFamilyHotel.Travel-Guide-Filter-Hotels) - [Hotels near Ancient Asine ](https://www.expedia.com/Ancient-Asine-Hotels.0-l6334168-0.Travel-Guide-Filter-Hotels) - 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