Find hotels near Don and Sybil Harrington Cancer Center, Amarillo from $73

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Our top choices for Don and Sybil Harrington Cancer Center hotels

Best Western Plus Medical Center

Best Western Plus Medical Center
2.5 star property
0.2 mi from Don and Sybil Harrington Cancer Center
9.4 out of 10, Exceptional, (2085)
"Staff was courteous and efficient with check-in. Room clean, well appointed and quiet. "
United States
James
$94 nightly
The price is $108
Jan 4 - Jan 5, 2026
Total with taxes and fees
Best Western Plus Medical Center

Holiday Inn Express & Suites Amarillo West by IHG

Holiday Inn Express & Suites Amarillo West by IHG
2.5 star property
0.9 mi from Don and Sybil Harrington Cancer Center
9.4 out of 10, Exceptional, (2019)
"Love the breakfast here!"
United States
Eric
$100 nightly
The price is $115
Jan 22 - Jan 23, 2026
Total with taxes and fees
Holiday Inn Express & Suites Amarillo West by IHG

Drury Inn & Suites Amarillo

Drury Inn & Suites Amarillo
3.0 star property
1.2 mi from Don and Sybil Harrington Cancer Center
9.4 out of 10, Exceptional, (2199)
"We had a great stay!! Friendly staff, clean rooms and enjoyed the amenities."
United States
Araceli
$85 nightly
The price is $98
Jan 4 - Jan 5, 2026
Total with taxes and fees
Drury Inn & Suites Amarillo

TownePlace Suites by Marriott Amarillo West/Medical Center

TownePlace Suites by Marriott Amarillo West/Medical Center
3.0 star property
0.7 mi from Don and Sybil Harrington Cancer Center
9.4 out of 10, Exceptional, (478)
"Room was very clean and staff were very professional and friendly."
United States
Rosabel
$113 nightly
The price is $130
Dec 28 - Dec 29
Total with taxes and fees
TownePlace Suites by Marriott Amarillo West/Medical Center

Hampton Inn & Suites Amarillo West

Hampton Inn & Suites Amarillo West
2.5 star property
1.1 mi from Don and Sybil Harrington Cancer Center
9.4 out of 10, Exceptional, (403)
"Clean room, friendly staff, comfortable bed and room decor. "
United States
Noemi
$105 nightly
The price is $120
Dec 31 - Jan 1, 2026
Total with taxes and fees
Hampton Inn & Suites Amarillo West

My Place Hotel - Amarillo West/ Medical Center, TX

My Place Hotel - Amarillo West/ Medical Center, TX
2.5 star property
1 mi from Don and Sybil Harrington Cancer Center
9.2 out of 10, Wonderful, (1310)
"Second time staying and enjoyed it again. Very clean."
United States
Stephen
$71 nightly
The price is $82
Dec 30 - Dec 31
Total with taxes and fees
My Place Hotel - Amarillo West/ Medical Center, TX

Yellow City Studios

Yellow City Studios
2.0 star property
0.6 mi from Don and Sybil Harrington Cancer Center
9.0 out of 10, Wonderful, (12)
"Highly recommend, clean, quiet and peaceful. The staff very nice and professional. "
United States
Jared
$77 nightly
The price is $89
Dec 24 - Dec 25
Total with taxes and fees
Yellow City Studios

Springhill Suites by Marriott Amarillo

Springhill Suites by Marriott Amarillo
3.0 star property
1 mi from Don and Sybil Harrington Cancer Center
9.2 out of 10, Wonderful, (1001)
"Great place"
United States
Mary
$107 nightly
The price is $123
Dec 31 - Jan 1, 2026
Total with taxes and fees
Springhill Suites by Marriott Amarillo

Hyatt Place Amarillo-West

Hyatt Place Amarillo-West
3.0 star property
1.4 mi from Don and Sybil Harrington Cancer Center
9.2 out of 10, Wonderful, (1369)
"We like to stay there when we head to Prescott, Arizona. It is convenient and has many restaurants around to chose from! The staff is super nice. "
United States
Charles
$86 nightly
The price is $98
Jan 4 - Jan 5, 2026
Total with taxes and fees
Hyatt Place Amarillo-West

Tru By Hilton Amarillo West

Tru By Hilton Amarillo West
2.5 star property
1.3 mi from Don and Sybil Harrington Cancer Center
9.2 out of 10, Wonderful, (1109)
"Great staff, the lobby area was fun with a little pool table and drink and snack station and room was great!"
United States
Lauren
$78 nightly
The price is $89
Dec 31 - Jan 1, 2026
Total with taxes and fees
Tru By Hilton Amarillo West

Home2 Suites by Hilton Amarillo

Home2 Suites by Hilton Amarillo
3.0 star property
0.8 mi from Don and Sybil Harrington Cancer Center
9.0 out of 10, Wonderful, (1009)
"Rooms are clean, spacious and pet friendly. The staff is friendly and helpful. "
United States
Lisa
$84 nightly
The price is $97
Jan 11 - Jan 12, 2026
Total with taxes and fees
Home2 Suites by Hilton Amarillo

Country Inn & Suites by Radisson, Amarillo I-40 West, TX

Country Inn & Suites by Radisson, Amarillo I-40 West, TX
3.0 star property
1.3 mi from Don and Sybil Harrington Cancer Center
9.0 out of 10, Wonderful, (2437)
"Best beds from this trip and warm atmosphere very welcoming "
United States
Donna
$71 nightly
The price is $81
Jan 4 - Jan 5, 2026
Total with taxes and fees
Country Inn & Suites by Radisson, Amarillo I-40 West, TX

Everhome Suites Amarillo West - Medical Center

Everhome Suites Amarillo West - Medical Center
2.0 star property
0.7 mi from Don and Sybil Harrington Cancer Center
8.8 out of 10, Excellent, (108)
"Easy stay and pet friendly. "
United States
Brittany
$84 nightly
The price is $97
Jan 6 - Jan 7, 2026
Total with taxes and fees
Everhome Suites Amarillo West - Medical Center

Microtel Inn & Suites By Wyndham Amarillo West

Microtel Inn & Suites By Wyndham Amarillo West
2.5 star property
1.3 mi from Don and Sybil Harrington Cancer Center
8.8 out of 10, Excellent, (583)
"Enjoyed our stay "
United States
Frank
$75 nightly
The price is $86
Dec 24 - Dec 25
Total with taxes and fees
Microtel Inn & Suites By Wyndham Amarillo West

Homewood Suites by Hilton Amarillo

Homewood Suites by Hilton Amarillo
3.0 star property
1.4 mi from Don and Sybil Harrington Cancer Center
8.8 out of 10, Excellent, (1000)
"Very clean, great staff, comfortable beds"
United States
Heather
$70 nightly
The price is $80
Jan 4 - Jan 5, 2026
Total with taxes and fees
Homewood Suites by Hilton Amarillo

Fairfield Inn & Suites Amarillo West/Medical Center

Fairfield Inn & Suites Amarillo West/Medical Center
2.5 star property
0.6 mi from Don and Sybil Harrington Cancer Center
8.4 out of 10, Very Good, (755)
"Very nice and helpful staff. "
United States
Alicia
$87 nightly
The price is $100
Dec 24 - Dec 25
Total with taxes and fees
Fairfield Inn & Suites Amarillo West/Medical Center

Comfort Inn & Suites Amarillo West near Medical Center

Comfort Inn & Suites Amarillo West near Medical Center
2.5 star property
1.3 mi from Don and Sybil Harrington Cancer Center
8.6 out of 10, Excellent, (1204)
"breakfast was really nice comfortable room and quiet."
United States
Layne
$64 nightly
The price is $73
Dec 30 - Dec 31
Total with taxes and fees
Comfort Inn & Suites Amarillo West near Medical Center

Sleep Inn & Suites West Medical Center

Sleep Inn & Suites West Medical Center
2.5 star property
0.7 mi from Don and Sybil Harrington Cancer Center
8.2 out of 10, Very Good, (1008)
"Great check in, room, bed... all really good! Thanks for a good night sleep. "
United States
Kristy
$64 nightly
The price is $74
Dec 30 - Dec 31
Total with taxes and fees
Sleep Inn & Suites West Medical Center

Spark by Hilton Amarillo Medical Center

Spark by Hilton Amarillo Medical Center
2.5 star property
0.7 mi from Don and Sybil Harrington Cancer Center
8.0 out of 10, Very Good, (744)
"Staff was nice and loved the area "
United States
Briones
$65 nightly
The price is $75
Dec 30 - Dec 31
Total with taxes and fees
Spark by Hilton Amarillo Medical Center

Holiday Inn Amarillo West Medical Center by IHG

Holiday Inn Amarillo West Medical Center by IHG
3.0 star property
0.9 mi from Don and Sybil Harrington Cancer Center
8.0 out of 10, Very Good, (1000)
"Awesome stay"
United States
Robert
$78 nightly
The price is $90
Jan 5 - Jan 6, 2026
Total with taxes and fees
Holiday Inn Amarillo West Medical Center by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Don and Sybil Harrington Cancer Center Hotel Reviews

Hotels near other Don and Sybil Harrington Cancer Center attractions

Frequently asked questions

What are the top-rated hotels near Don and Sybil Harrington Cancer Center?
Discovering top-rated hotels near Don and Sybil Harrington Cancer Center ensures a comfortable stay for travelers seeking quality and convenience in Amarillo, Texas.

The Riley. Retro charm in the Heart of DT Amarillo. Near I-40 & Historic Rt 66

The Riley is a charming accommodation just 4.8 miles from Don and Sybil Harrington Cancer Center, with an impressive review rating of 10. This hotel features a cozy kitchenette equipped with a refrigerator, microwave, and coffee maker, making it perfect for travelers who enjoy the convenience of preparing their own meals. With a delightful patio area, travelers can relax outdoors and take in the local atmosphere.

Studio Collin. Ideal Downtown property 4 work/play/relax. Near I-40 & Hist Rt 66

Studio Collin provides an exceptional stay with a stellar review rating of 10, located just 4.8 miles from Don and Sybil Harrington Cancer Center. This hotel features a well-equipped kitchenette and a welcoming patio, making it an ideal choice for travelers looking to unwind after a busy day. Its modern amenities, including air conditioning and dining facilities, ensure a comfortable and enjoyable experience.

Yellow Guest House near I-40 and I-27

Yellow Guest House is a standout option with a review rating of 10 and a solid 4-star rating, situated just 4.6 miles from Don and Sybil Harrington Cancer Center. Guests can enjoy a spacious kitchen with an oven and stovetop, perfect for those who love to cook. The hotel also features a beautiful garden and a secured yard, providing a serene escape while still being close to the city's attractions.
What hotels are within walking distance to Don and Sybil Harrington Cancer Center?
Discover the perfect accommodations for your visit to the Don and Sybil Harrington Cancer Center, with top-rated options that ensure comfort and convenience.

Best Western Plus Medical Center

Best Western Plus Medical Center is a welcoming retreat located just a 9-minute walk from the Don and Sybil Harrington Cancer Center. Rated 9.4 by travelers, this hotel features an indoor pool where travelers can unwind after a long day. With amenities like free breakfast daily, a fitness center, and well-equipped rooms including a refrigerator and microwave, it's a convenient choice for those visiting the area.

Home2 Suites by Hilton Amarillo

Home2 Suites by Hilton Amarillo offers a modern stay just 18 minutes away from the Don and Sybil Harrington Cancer Center. This 3-star hotel boasts a review rating of 9.0, providing travelers with an indoor pool and a 24-hour fitness center. Guests can enjoy complimentary breakfast and the convenience of in-room kitchens, making it ideal for longer stays or those who prefer to prepare their own meals.

Everhome Suites Amarillo West - Medical Center

Everhome Suites Amarillo West - Medical Center is located 20 minutes from the Don and Sybil Harrington Cancer Center and offers a review rating of 8.2. This hotel features a variety of amenities, including kitchens in each suite, making it a great option for travelers looking for flexibility during their stay. With 24-hour fitness facilities and easy access to nearby golf courses and museums, travelers can enjoy both relaxation and recreation.
How much is a hotel near Don and Sybil Harrington Cancer Center?
Staying near Don and Sybil Harrington Cancer Center is a treat, with plenty of hotels from $73 offering incredible amenities. If you're leaning toward a little luxury, prices can rise, especially in peak season. Be sure to book in advance to enjoy more options and potentially better rates, especially if you're planning a vacation during weekends or around public holidays.
What are the most popular family-friendly hotels near Don and Sybil Harrington Cancer Center?
For families looking for top-rated hotels near Don and Sybil Harrington Cancer Center, Amarillo offers several excellent options that cater to both comfort and convenience.

Holiday Inn Amarillo West Medical Center by IHG

Holiday Inn Amarillo West Medical Center by IHG is just 1.4 miles from the Don and Sybil Harrington Cancer Center, making it a convenient choice for families. This 3-star hotel is rated 8.0 by travelers and features family-friendly amenities such as an indoor pool, free cribs, and connecting rooms. Guests can enjoy a daily breakfast and kid's meals at the on-site restaurant, ensuring a straightforward stay for families.

Homewood Suites by Hilton Amarillo

Homewood Suites by Hilton Amarillo, located 2.0 miles from Don and Sybil Harrington Cancer Center, boasts an impressive review rating of 8.8. This 3-star hotel offers spacious suites with kitchen facilities, making it ideal for families. Guests can enjoy accessible pool facilities, free breakfasts, and cribs, providing a perfect home-away-from-home experience for traveling families.

Hilton Garden Inn Amarillo

Hilton Garden Inn Amarillo is situated 3.9 miles from the Don and Sybil Harrington Cancer Center and holds a traveler rating of 8.0. This 3-star hotel offers family-friendly amenities including an indoor pool, free cribs, and rooms with video game consoles, ensuring entertainment for kids. With its convenient location and comfortable accommodations, it's a great choice for families visiting Amarillo.
What are the best affordable hotels near Don and Sybil Harrington Cancer Center?
For those seeking affordable stays near Don and Sybil Harrington Cancer Center, these top-rated hotels offer excellent options without breaking the bank.

The Riley. Retro charm in the Heart of DT Amarillo. Near I-40 & Historic Rt 66

The Riley is a budget-friendly gem located just 4.8 miles from Don and Sybil Harrington Cancer Center, with a perfect review rating of 10. This hotel is ideal for families, featuring a kitchenette equipped with a refrigerator, microwave, and dining table, making it easy to prepare meals. Guests will also appreciate the charming patio and complimentary WiFi, ensuring a cozy and connected stay.

Studio Collin. Ideal Downtown property 4 work/play/relax. Near I-40 & Hist Rt 66

Studio Collin, also 4.8 miles from Don and Sybil Harrington Cancer Center, shares the same excellent review rating of 10. It's perfect for families or those needing a comfortable place for work, play, or relaxation. With amenities like a kitchenette, patio, and free WiFi, travelers can enjoy a cozy feel while being close to all the action.

Drury Inn & Suites Amarillo

Drury Inn & Suites Amarillo is a fantastic mid-range option situated just 1.8 miles from Don and Sybil Harrington Cancer Center, rated highly by travelers with a review rating of 9.4 and a 3-star designation. This family-friendly hotel offers a complimentary breakfast buffet, indoor pool, and hot tub, ensuring a delightful stay. Additional amenities include free WiFi, self-parking, and cribs for families traveling with young children.
Are there any hotels with pools close to Don and Sybil Harrington Cancer Center?
For those seeking a refreshing stay near Don and Sybil Harrington Cancer Center, these top-rated hotels with pools in Amarillo offer comfort and convenience.

Drury Inn & Suites Amarillo

Drury Inn & Suites Amarillo is just 1.8 miles from Don and Sybil Harrington Cancer Center, featuring an inviting indoor pool perfect for relaxation. Rated 9.4 by travelers, this 3-star hotel also offers complimentary hot breakfast, free parking, and a hot tub for added comfort. Guests can enjoy the convenience of a microwave in their rooms and the spacious terrace for unwinding after a long day.

TownePlace Suites by Marriott Amarillo West/Medical Center

Located only 1.3 miles from Don and Sybil Harrington Cancer Center, TownePlace Suites by Marriott Amarillo West/Medical Center boasts an accessible indoor pool, ideal for travelers of all abilities. With a review rating of 9.4, this 3-star hotel offers a free buffet breakfast daily, a rooftop garden, and 24-hour fitness facilities. Guests appreciate the comfort of in-room microwaves and dishwashers, making it perfect for longer stays.

Hyatt Place Amarillo-West

Hyatt Place Amarillo-West is conveniently situated just 1.7 miles from Don and Sybil Harrington Cancer Center and features an accessible indoor pool, ensuring a refreshing experience for all travelers. With a great traveler rating score of 9.2, this 3-star hotel provides 24-hour fitness facilities and comfortable accommodations with premium bedding. Guests can also take advantage of free self-parking and the nearby mountain biking opportunities.
What are the best pet-friendly hotels near Don and Sybil Harrington Cancer Center?
For those seeking top-rated, pet-friendly accommodations near Don and Sybil Harrington Cancer Center, there are several great options in Amarillo that welcome both you and your furry friends.

Everhome Suites Amarillo West - Medical Center

Everhome Suites Amarillo West - Medical Center is a fantastic choice for pet owners, situated only 1.3 miles from Don and Sybil Harrington Cancer Center. With an impressive review rating of 8.2, this hotel provides pet-friendly amenities and a welcoming atmosphere. Guests will appreciate the fully-equipped kitchens, a 24-hour fitness center, and easy access to nearby golf courses. The hotel also offers free self-parking and a snack bar, ensuring a restful and enjoyable stay.

Red Roof Inn Amarillo West

Red Roof Inn Amarillo West is conveniently located just 1.4 miles from Don and Sybil Harrington Cancer Center. With a travelers' rating of 6.6, this hotel ensures a comfortable stay for travelers traveling with pets, offering amenities such as in-room pet allowances and service animal support. Guests can enjoy a free continental breakfast, air conditioning, and a kitchenette to make their stay more convenient. The hotel also features free self-parking and an accessible pool for leisure.

Relax Inn West Amarillo Medical Center

Relax Inn West Amarillo Medical Center is a pet-friendly hotel located a 20-minute walk from Don and Sybil Harrington Cancer Center. With a review rating of 6.6, this hotel allows pets in designated rooms and provides essential amenities like free self-parking and daily housekeeping. Guests can unwind at the accessible pool or take advantage of the nearby shopping district. The hotel also offers air conditioning for added comfort during your stay.
Can I book a fully refundable hotel close to Don and Sybil Harrington Cancer Center?
Most bookings on Expedia are refundable if canceled within 24-48 hours of arrival, though this depends on the hotel's individual cancellation policy, which you should check in your booking confirmation. If free cancellation is available, you can cancel directly through your Expedia account by going to "My Trips" and selecting your reservation. To find fully refundable hotel options, simply enter "Don and Sybil Harrington Cancer Center", set your travel dates, and use the "Fully refundable" filter under "Deals & Discounts" on the results page. Alternatively, explore deals with free cancellation options on Expedia.
Can I find Expedia discounts for hotels near Don and Sybil Harrington Cancer Center?
To look for discounts on hotels near Don and Sybil Harrington Cancer Center, join One Key™—our free travel rewards program. One Key members always get our best prices and earn OneKeyCash™* on eligible bookings for every dollar spent. Another way to save is by bundling your hotel and flights together on Expedia.

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