Grand Isle Vacations from $549

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Your Grand Isle Vacation

Immerse yourself in all this neighborhood has to offer with a tailor-made Grand Isle vacation package. However you see yourself spending your time here, you'll find countless opportunities for adventure, relaxation and fun. If you're into sightseeing, no trip to Grand Isle is complete without visiting nearby Mexico Beach. Expedia is here to help put your plans into action. Book your dream Grand Isle vacation now.

The Latest Grand Isle Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Landmark Holiday Beach Resort

Landmark Holiday Beach Resort

3.5 out of 5
Price was $725, price is now $549 per person
$549
per person
Jan 23 - Jan 29
found 1 day ago
Roundtrip non-stop flight included
Chicago (CHI) to Panama City (ECP)
8.6/10 Excellent! (219 reviews)
Kitchen has everything you need along with washer and dryer.. Beautiful beachfront view .

Reviewed on Oct 27, 2025

The Pearl Hotel

The Pearl Hotel

4 out of 5
Rosemary Beach
Save 100% on your flight
Price was $2,102, price is now $1,510 per person
$1,510
per person
Jan 23 - Jan 29
found 1 day ago
Roundtrip non-stop flight included
Chicago (CHI) to Panama City (ECP)
9.4/10 Exceptional! (188 reviews)
Very clean and the staff was very pleasant and helpful.

Reviewed on Dec 12, 2025

Camp Creek Inn

Camp Creek Inn

4 out of 5
Price was $1,257, price is now $973 per person
$973
per person
Jan 16 - Jan 20
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Panama City (ECP)
9.8/10 Exceptional! (125 reviews)
Very welcoming staff, excellent food and clean, beautiful room with very nice balcony seating area

Reviewed on Dec 14, 2025

Margaritaville Beach Cottage Resort PCB

Margaritaville Beach Cottage Resort PCB

4.5 out of 5
Price was $949, price is now $743 per person
$743
per person
Feb 19 - Feb 22
found 1 day ago
Roundtrip non-stop flight included
Indianapolis (IND) to Panama City (ECP)
9.4/10 Exceptional! (10 reviews)
Excellent place to stay

Reviewed on Dec 4, 2025

Newly Renovated! 2-min Walk to the Beach The Coastal Cottage by Avantstay

Newly Renovated! 2-min Walk to the Beach The Coastal Cottage by Avantstay

3 out of 5
Sunnyside
Price was $1,595, price is now $1,254 per person
$1,254
per person
Feb 5 - Feb 9
found 1 day ago
Roundtrip non-stop flight included
New York (JFK) to Panama City (ECP)
No reviews

Where to stay in Grand Isle

Find the best Grand Isle areas and neighborhoods for the activities you enjoy most. Learn more about Grand Isle
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Downtown Port St. Joe

While visiting Downtown Port St. Joe, you might make a stop by sights like Port Saint Joe City Hall and Port St. Joe Marina.

Find hotels in Downtown Port St. Joe

Grand Isle Hotel Deals

Candlewood Suites Panama City Tyndall AFB by IHG

Candlewood Suites Panama City Tyndall AFB by IHG

2.5 out of 5
131 N.Tyndall Parkway Panama City FL
Fully refundable
$94 nightly
The price is $101 total per night from Dec 24 to Dec 25
$101 total
Dec 24 - Dec 25
Total with taxes and fees
9.6/10 Exceptional! (33 reviews)
Everything I was so amazed at how much I got accomplished w all the stuff provided and was able to make my thanksgiving dinner for family we were visiting and also washing was such a blessing also I will definitely be using I all again

Reviewed on Dec 2, 2025

Candlewood Suites Panama City Tyndall AFB by IHG
MainStay Suites Port Saint Joe South

MainStay Suites Port Saint Joe South

2.5 out of 5
3951 E Highway 98 Port St. Joe FL
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $123 total per night from Dec 21 to Dec 22
$123 total
Dec 21 - Dec 22
Total with taxes and fees
8.4/10 Very Good! (694 reviews)
Everything was great. Friendly, accommodating staff. Awesome breakfast

Reviewed on Nov 30, 2025

MainStay Suites Port Saint Joe South
Comfort Suites

Comfort Suites

2.5 out of 5
264 N Tyndall Pkwy Panama City FL
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $91 total per night from Jan 1 to Jan 2
$91 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
8.4/10 Very Good! (712 reviews)
I had great experience. Just was disappointed the property pictures showed a hot tub, but the hot tub was no longer there, and the pool was ice cold, no heater. Other than that. Overall great experience

Reviewed on Nov 29, 2025

Comfort Suites
See all 2,209 properties in Grand Isle
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Discover the most popular places to visit in Grand Isle

Cape San Blas Lighthouse

Cape San Blas Lighthouse

4.5/5(19 reviews)

Learn about the local history of Cape San Blas when you spend time at Cape San Blas Lighthouse. Wander the beautiful beaches in this relaxing area.

Cape San Blas Lighthouse
The sand is so white it almost looks like fresh powder.

T.H. Stone Memorial St. Joseph Peninsula State Park

4/5(12 reviews)

You can take time to visit T.H. Stone Memorial St. Joseph Peninsula State Park during your travels to Port St. Joe. Wander the beautiful beaches in this relaxing area.

T.H. Stone Memorial St. Joseph Peninsula State Park
Sunset through the sea oats at Cape San Blas, Florida. Beautiful beaches, very quite; a perfect place to come and relax.

Beach

Why not spend a lazy afternoon at Beach during your trip to Cape San Blas? Wander the beautiful beaches in this relaxing area.

Beach
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.