
Grand Isle Vacations from $597
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Your Grand Isle Vacation
Immerse yourself in all this neighborhood has to offer with a tailor-made Grand Isle vacation package. However you see yourself spending your time here, you'll find countless opportunities for adventure, relaxation and fun. If you're into sightseeing, no trip to Grand Isle is complete without visiting nearby Mexico Beach. Expedia is here to help put your plans into action. Book your dream Grand Isle vacation now.
The Latest Grand Isle Vacation Packages



30A Emerald Waters by Avantstay Pool + Bikes + Bonfires
Reviewed on Aug 27, 2025

WaterSound Inn
Reviewed on Dec 13, 2024

The Pearl Hotel
Reviewed on Oct 14, 2025
Where to stay in Grand Isle

Downtown Port St. Joe
While visiting Downtown Port St. Joe, you might make a stop by sights like Port Saint Joe City Hall and Constitution Convention Museum State Park.
Grand Isle Hotel Deals

MainStay Suites Port Saint Joe South
Everything was perfect... exactlywhat I was looking for. Nice spot and 5 mins from gorgeous Port St. Joe.
Reviewed on Oct 6, 2025

Comfort Suites
Staff was friendly and helpful. Carpets could stand a cleaning, rooms were comfortable and the most part very clean, just need to do a little look see to repair a few flaws. Bed was very comfortable, plenty of comfortable pillows and plenty of towels . When we’re in the area again, we will for sure ...
Reviewed on Oct 5, 2025

Days Inn by Wyndham Panama City/Callaway
The room was huge. Nicely laid out. Mattress was wonderful. Plenty of hot water. Large frig. Microwave oven. Nice TV. Staff were great. Breakfast was lacking in options. Yogurt and coffee only. But Waffle House across the street. Overall a great stay. Would book here again without a doubt.
Reviewed on Oct 6, 2025
Discover the most popular places to visit in Grand Isle

Cape San Blas Lighthouse
Learn about the local history of Cape San Blas when you spend time at Cape San Blas Lighthouse. Wander the beautiful beaches in this relaxing area.

T.H. Stone Memorial St. Joseph Peninsula State Park
You can take time to visit T.H. Stone Memorial St. Joseph Peninsula State Park during your travels to Port St. Joe. Wander the beautiful beaches in this relaxing area.

Beach
Why not spend a lazy afternoon at Beach during your trip to Cape San Blas? Wander the beautiful beaches in this relaxing area.


















