Grand Isle Vacations from $462

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Your Grand Isle Vacation

Immerse yourself in all this neighborhood has to offer with a tailor-made Grand Isle vacation package. However you see yourself spending your time here, you'll find countless opportunities for adventure, relaxation and fun. If you're into sightseeing, no trip to Grand Isle is complete without visiting nearby Mexico Beach. Expedia is here to help put your plans into action. Book your dream Grand Isle vacation now.

The Latest Grand Isle Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Studios at Fontainebleau Terrace

Studios at Fontainebleau Terrace

3.5 out of 5
Price was $715, price is now $462 per person
$462
per person
Oct 17 - Oct 19
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to Panama City (ECP)
10/10 Exceptional! (1 review)
Nice employees clean room would have been perfect if it had a private balcony will come visit again!

Reviewed on Jun 25, 2025

Halcyon Dayz by Avantstay New Build w/ Pool Access

Halcyon Dayz by Avantstay New Build w/ Pool Access

3 out of 5
Save 100% on your flight
Price was $3,659, price is now $2,467 per person
$2,467
per person
Nov 11 - Nov 18
found 1 day ago
Roundtrip flight included
Dallas (DFW) to Panama City (ECP)
No reviews
30A Wave and Sea by Avantstay Lagoon Pool, Walk to Beach

30A Wave and Sea by Avantstay Lagoon Pool, Walk to Beach

3 out of 5
Rosemary Beach
Save 100% on your flight
Price was $2,027, price is now $1,437 per person
$1,437
per person
Nov 11 - Nov 18
found 1 day ago
Roundtrip flight included
Dallas (DFW) to Panama City (ECP)
No reviews
Newly Renovated! 2-min Walk to the Beach The Coastal Cottage by Avantstay

Newly Renovated! 2-min Walk to the Beach The Coastal Cottage by Avantstay

3 out of 5
Sunnyside
Save 100% on your flight
Price was $2,094, price is now $1,512 per person
$1,512
per person
Nov 11 - Nov 18
found 1 day ago
Roundtrip flight included
Dallas (DFW) to Panama City (ECP)
No reviews
The Palmetto Blue by Avantstay Steps to Beach, Ocean Views

The Palmetto Blue by Avantstay Steps to Beach, Ocean Views

3 out of 5
Inlet Beach
Save 100% on your flight
Price was $2,448, price is now $1,770 per person
$1,770
per person
Nov 11 - Nov 18
found 1 day ago
Roundtrip flight included
Dallas (DFW) to Panama City (ECP)
No reviews

Where to stay in Grand Isle

Find the best Grand Isle areas and neighborhoods for the activities you enjoy most. Learn more about Grand Isle
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Downtown Port St. Joe

While visiting Downtown Port St. Joe, you might make a stop by sights like Port Saint Joe City Hall and Port St. Joe Marina.

Find hotels in Downtown Port St. Joe

Grand Isle Hotel Deals

MainStay Suites Port Saint Joe South

MainStay Suites Port Saint Joe South

2.5 out of 5
3951 E Highway 98, Port St. Joe, FL
Fully refundableReserve now, pay when you stay
$125 nightly
The price is $140 total per night from Sep 14 to Sep 15
$140 total
Sep 14 - Sep 15
Total with taxes and fees
MainStay Suites Port Saint Joe South
Comfort Suites

Comfort Suites

2.5 out of 5
264 N Tyndall Pkwy, Panama City, FL
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $86 total per night from Sep 14 to Sep 15
$86 total
Sep 14 - Sep 15
Total with taxes and fees
Comfort Suites
Days Inn by Wyndham Panama City/Callaway

Days Inn by Wyndham Panama City/Callaway

2 out of 5
435 North Tyndall Parkway, Hwy 98 & Hwy 22, Panama City, FL
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $69 total per night from Sep 8 to Sep 9
$69 total
Sep 8 - Sep 9
Total with taxes and fees
Days Inn by Wyndham Panama City/Callaway
See all 2,147 properties in Grand Isle
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
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Discover the most popular places to visit in Grand Isle

Cape San Blas Lighthouse

Cape San Blas Lighthouse

Learn about the local history of Cape San Blas when you spend time at Cape San Blas Lighthouse. Wander the beautiful beaches in this relaxing area.

Cape San Blas Lighthouse
The sand is so white it almost looks like fresh powder.

T.H. Stone Memorial St. Joseph Peninsula State Park

You can take time to visit T.H. Stone Memorial St. Joseph Peninsula State Park during your travels to Port St. Joe. Wander the beautiful beaches in this relaxing area.

T.H. Stone Memorial St. Joseph Peninsula State Park
Sunset through the sea oats at Cape San Blas, Florida. Beautiful beaches, very quite; a perfect place to come and relax.

Beach

Why not spend a lazy afternoon at Beach during your trip to Cape San Blas? Wander the beautiful beaches in this relaxing area.

Beach
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.