Isolotto Vacations

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Your Isolotto Vacation

Reserving a tailor-made Isolotto vacation package is a good way to know the ins and outs of this unique neighborhood. From its must-see spots to its lesser-known delights, there's a lot to delve into. When it's time to head out and explore, you'll find plenty of popular attractions nearby including Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Visit one, two or more during your trip to Isolotto. Stop dreaming and start doing. When it's time to book your next vacation to Isolotto, Expedia is here to help.

Where to stay in Isolotto

Find the best Isolotto areas and neighborhoods for the activities you enjoy most. Learn more about Isolotto

Isolotto Hotel Deals

The Social Hub Florence Lavagnini

The Social Hub Florence Lavagnini

4 out of 5
Viale Spartaco Lavagnini 70 72 Florence FI
Fully refundableReserve now, pay when you stay
$143 nightly
The price is $174 total per night from Apr 12 to Apr 13
$174 total
Apr 12 - Apr 13
Total with taxes and fees
9/10 Wonderful! (1,329 reviews)
The hotel is located right next to a tram so it’s very easy to get there from the train station. It is about a 15 minute walk away from the Duomo and even further for the river and museums so that’s something to consider. I think this is one of the few hotels that has an elevator in it which is a ...

Reviewed on Apr 10, 2026

The Social Hub Florence Lavagnini
IQ Hotel Firenze

IQ Hotel Firenze

4 out of 5
Via Camillo Cavour, 88 Florence FI
$196 nightly
The price is $232 total per night from Apr 12 to Apr 13
$232 total
Apr 12 - Apr 13
Total with taxes and fees
9.6/10 Exceptional! (1,215 reviews)
The rome was immaculate! Excellent customer service. Every body were very warm and accommodating. Location is safe and walkable. Good breakfast options. No complains here! Was very happy with our stay, free water and snacks that were replenished everyday.

Reviewed on Apr 10, 2026

IQ Hotel Firenze
Hotel Machiavelli Palace

Hotel Machiavelli Palace

3 out of 5
Via Nazionale 10 Florence FI
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $139 total per night from Apr 12 to Apr 13
$139 total
Apr 12 - Apr 13
Total with taxes and fees
8.4/10 Very Good! (173 reviews)
Breakfast very fresh and large buffet Very nice staff .only problem i had was mattress was too hard and pilllow was too soft .

Reviewed on Apr 2, 2026

Hotel Machiavelli Palace
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Isolotto

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.