Isolotto Vacations from $1,433

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Your Isolotto Vacation

Reserving a tailor-made Isolotto vacation package is a good way to know the ins and outs of this unique neighborhood. From its must-see spots to its lesser-known delights, there's a lot to delve into. When it's time to head out and explore, you'll find plenty of popular attractions nearby including Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Visit one, two or more during your trip to Isolotto. Stop dreaming and start doing. When it's time to book your next vacation to Isolotto, Expedia is here to help.

The Latest Isolotto Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Aurum Uffizi
Villa Cora
Maxim Axial
The Place Firenze
Residenza Florentia

Where to stay in Isolotto

Find the best Isolotto areas and neighborhoods for the activities you enjoy most. Learn more about Isolotto

Isolotto Hotel Deals

The Social Hub Florence Lavagnini

The Social Hub Florence Lavagnini

4 out of 5
Viale Spartaco Lavagnini 70 72 Florence FI
Fully refundableReserve now, pay when you stay
$142 nightly
The price is $172 total per night from Apr 12 to Apr 13
$172 total
Apr 12 - Apr 13
Total with taxes and fees
9/10 Wonderful! (1,322 reviews)
Comfy hotel, spacious, loved the roof top gym.

Reviewed on Apr 8, 2026

The Social Hub Florence Lavagnini
IQ Hotel Firenze

IQ Hotel Firenze

4 out of 5
Via Camillo Cavour, 88 Florence FI
Fully refundableReserve now, pay when you stay
$137 nightly
The price is $168 total per night from Apr 12 to Apr 13
$168 total
Apr 12 - Apr 13
Total with taxes and fees
9.6/10 Exceptional! (1,211 reviews)
We really enjoyed our stay at iQ Hotel Firenze. The hotel is modern, very clean, and in a great location close to the city center, which made it easy to explore Florence. The breakfast was excellent, with a wide variety of food and many healthy options. The staff was also very helpful and welcoming. ...

Reviewed on Apr 8, 2026

IQ Hotel Firenze
Hotel Machiavelli Palace

Hotel Machiavelli Palace

3 out of 5
Via Nazionale 10 Florence FI
Fully refundableReserve now, pay when you stay
$153 nightly
The price is $182 total per night from Apr 12 to Apr 13
$182 total
Apr 12 - Apr 13
Total with taxes and fees
8.4/10 Very Good! (172 reviews)
Breakfast very fresh and large buffet Very nice staff .only problem i had was mattress was too hard and pilllow was too soft .

Reviewed on Apr 2, 2026

Hotel Machiavelli Palace
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Isolotto

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.