Isolotto Vacations from $1,378

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Your Isolotto Vacation

Reserving a tailor-made Isolotto vacation package is a good way to know the ins and outs of this unique neighborhood. From its must-see spots to its lesser-known delights, there's a lot to delve into. When it's time to head out and explore, you'll find plenty of popular attractions nearby including Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Visit one, two or more during your trip to Isolotto. Stop dreaming and start doing. When it's time to book your next vacation to Isolotto, Expedia is here to help.

The Latest Isolotto Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Aurum Firenze
Aurum Uffizi
Precise Tale Poggio Alla Sala
LHP Hotel River & SPA
Eurostars Florence Boutique

Where to stay in Isolotto

Find the best Isolotto areas and neighborhoods for the activities you enjoy most. Learn more about Isolotto

Isolotto Hotel Deals

The Social Hub Florence Lavagnini

The Social Hub Florence Lavagnini

4 out of 5
Viale Spartaco Lavagnini 70 72 Florence FI
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $191 total per night from Apr 24 to Apr 25
$191 total
Apr 24 - Apr 25
Total with taxes and fees
9/10 Wonderful! (1,330 reviews)
Great experience

Reviewed on Apr 12, 2026

The Social Hub Florence Lavagnini
IQ Hotel Firenze

IQ Hotel Firenze

4 out of 5
Via Camillo Cavour, 88 Florence FI
Fully refundableReserve now, pay when you stay
$218 nightly
The price is $256 total per night from Apr 20 to Apr 21
$256 total
Apr 20 - Apr 21
Total with taxes and fees
9.6/10 Exceptional! (1,217 reviews)
Great convenient place

Reviewed on Apr 12, 2026

IQ Hotel Firenze
Hotel Machiavelli Palace

Hotel Machiavelli Palace

3 out of 5
Via Nazionale 10 Florence FI
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $167 total per night from Apr 17 to Apr 18
$167 total
Apr 17 - Apr 18
Total with taxes and fees
8.4/10 Very Good! (175 reviews)
Breakfast very fresh and large buffet Very nice staff .only problem i had was mattress was too hard and pilllow was too soft .

Reviewed on Apr 2, 2026

Hotel Machiavelli Palace
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Isolotto

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.