Isolotto Vacations from $914

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Your Isolotto Vacation

Reserving a tailor-made Isolotto vacation package is a good way to know the ins and outs of this unique neighborhood. From its must-see spots to its lesser-known delights, there's a lot to delve into. When it's time to head out and explore, you'll find plenty of popular attractions nearby including Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Visit one, two or more during your trip to Isolotto. Stop dreaming and start doing. When it's time to book your next vacation to Isolotto, Expedia is here to help.

The Latest Isolotto Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hotel La Scaletta Al Ponte Vecchio
Eurostars Florence Boutique
The Moon Boutique Hotel & Spa
Allegroitalia San Gallo Firenze
Relais Uffizi, Tailor made Hotel

Where to stay in Isolotto

Find the best Isolotto areas and neighborhoods for the activities you enjoy most. Learn more about Isolotto

Isolotto Hotel Deals

c-hotels Ambasciatori

c-hotels Ambasciatori

4 out of 5
Via Luigi Alamanni 3 Florence FI
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $115 total per night from Feb 22 to Feb 23
$115 total
Feb 22 - Feb 23
Total with taxes and fees
8.2/10 Very Good! (1,002 reviews)
Great location, short walk to the Duomo, museums and shopping. A clean quiet room awaited me.

Reviewed on Jan 21, 2026

c-hotels Ambasciatori
IQ Hotel Firenze

IQ Hotel Firenze

4 out of 5
Via Camillo Cavour, 88 Florence FI
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $122 total per night from Feb 5 to Feb 6
$122 total
Feb 5 - Feb 6
Total with taxes and fees
9.6/10 Exceptional! (1,133 reviews)
Fantastic service, exceptionallly clean room, free drink and minibar was a nice addition. Highly recommend. Lovely coming home after a day sightseeing.

Reviewed on Feb 1, 2026

IQ Hotel Firenze
Bernini Palace

Bernini Palace

5 out of 5
Piazza San Firenze 29 Florence FI
Fully refundableReserve now, pay when you stay
$235 nightly
The price is $277 total per night from Feb 22 to Feb 23
$277 total
Feb 22 - Feb 23
Total with taxes and fees
9.6/10 Exceptional! (1,003 reviews)
Staff very helpful Rooms very clean Good breakfast options

Reviewed on Jan 30, 2026

Bernini Palace
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Isolotto

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.