Massachusetts may have travel restrictions in place, including self-quarantine, due to COVID-19.

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Main Street Hyannis Vacation Packages

Choose one or more items to build your trip:

Main Street Hyannis Vacation: Coronavirus Information

Most Main Street Hyannis hotels offer free cancellation. Consider booking refundable hotels rather than non-refundable ones. Just look for the ‘free cancellation’ message during your hotel search. Prices can vary, but right now we believe that flexibility matters.

For more information about the impact of COVID-19 on your Main Street Hyannis trip, please visit our Coronavirus Information page (opens in new window).

Top Main Street Hyannis Flight + Hotel Deals

Renaissance Boston Waterfront Hotel

Renaissance Boston Waterfront Hotel

4 out of 5
Seaport District
$499

$390

per person
Apr 1 - Apr 4
Roundtrip flight included
Los Angeles (LAX) to Boston (BOS)
4.4/5Excellent! (1,000 reviews)

"I liked pretty much everything about this hotel, just wish the sign for it was more visible... uber drivers had a hard time finding it. Wish the menu for the restaurant was bigger. All and all a very nice place to stay.…"

Reviewed on Mar 3, 2020

Seaport Hotel Boston

Seaport Hotel Boston

4 out of 5
Seaport District
$492

$417

per person
Apr 1 - Apr 4
Roundtrip flight included
Los Angeles (LAX) to Boston (BOS)
4.8/5Exceptional! (2,024 reviews)

"The front desk staff was pleasant and courteous. The room was clean and the view was great on the Boston Harbor.…"

Reviewed on Jan 17, 2021

Hotel Commonwealth

Hotel Commonwealth

4.5 out of 5
Fenway–Kenmore
$508

$447

per person
Apr 1 - Apr 4
Roundtrip flight included
Los Angeles (LAX) to Boston (BOS)
4.6/5Wonderful! (1,326 reviews)

"Great group of amazingly kind and helpful staff! Whenever I’d call the front desk for questions or a favor it's immediately getting done. Lovely suites and some great views!…"

Reviewed on Jan 6, 2021

Club Quarters Hotel in Boston

Club Quarters Hotel in Boston

4 out of 5
Downtown Crossing
$394

$347

per person
Apr 1 - Apr 4
Roundtrip flight included
Los Angeles (LAX) to Boston (BOS)
4.2/5Very Good! (1,626 reviews)

"Friendly staff, you get your temperature checked at the door, contactless check-in & check-out, location of the hotel is great. BUT the room was tiny & almost every room on our floor was occupied (very loud)…"

Reviewed on Jan 16, 2021

Lakeside Inn

Lakeside Inn

2 out of 5
$335

$297

per person
Apr 1 - Apr 4
Roundtrip flight included
Los Angeles (LAX) to Boston (BOS)
3.5/5Good! (1,737 reviews)

"Very nice old timey hotel, lake view was very nice specially since we got to wake up to fresh snow.…"

Reviewed on Dec 22, 2020

2021 Main Street Hyannis vacation deals

Lakeside Inn

Lakeside Inn

2 out of 5
$385

$317

per person
Mar 22 - Mar 26
Roundtrip flight included
Dallas (DFW) to Boston (BOS)
3.5/5Good! (1,737 reviews)

"Very nice old timey hotel, lake view was very nice specially since we got to wake up to fresh snow.…"

Reviewed on Dec 22, 2020

Courtyard by Marriott Boston Logan Airport

Courtyard by Marriott Boston Logan Airport

3 out of 5
Harbor View - Orient Heights
$463

$387

per person
Mar 22 - Mar 26
Roundtrip flight included
Dallas (DFW) to Boston (BOS)
4.3/5Excellent! (1,001 reviews)

"The room was nice and the location convenient. The shuttle service was frequent and convenient.…"

Reviewed on Jan 2, 2021

TownePlace Suites Boston Logan Airport/Chelsea

TownePlace Suites Boston Logan Airport/Chelsea

3 out of 5
$518

$434

per person
Mar 22 - Mar 26
Roundtrip flight included
Dallas (DFW) to Boston (BOS)
4.6/5Wonderful! (998 reviews)

"It was great, but don`t count on the free breakfast that´s included in the price. They might run out of it like it happened with my party.…"

Reviewed on Oct 29, 2020

Red Roof Inn PLUS+ Boston - Woburn/ Burlington

Red Roof Inn PLUS+ Boston - Woburn/ Burlington

2.5 out of 5
$395

$334

per person
Mar 22 - Mar 26
Roundtrip flight included
Dallas (DFW) to Boston (BOS)
3.6/5Good! (1,000 reviews)

"Solid infrastructure. Large bathroom space & strong water flow for bath. Bed side table has four consent. Wooden floor, coffee & tea are inside the room. Comfortable bed. Facility's laundry locates on the 5th floor.…"

Reviewed on Jan 14, 2021

The Godfrey Hotel Boston

The Godfrey Hotel Boston

4 out of 5
Downtown Crossing
$549

$469

per person
Jan 28 - Jan 31
Roundtrip flight included
Dallas (DFW) to Boston (BOS)
4.6/5Wonderful! (2,284 reviews)

"Location was perfect! And loved that George Howell was eight downstairs…"

Reviewed on Jan 4, 2021

Top Hotels in Main Street Hyannis

Hyannis Plaza Hotel
Hyannis Plaza Hotel
2.5 out of 5
662 Main Street, Hyannis, MA
Free CancellationReserve now, pay when you stay
The price is $70 per night from Jan 24 to Jan 25
3/5 (90 reviews)

"I like how the bathroom was very clean and the hot tub was absolutely amazing. We loved it and I’d go back again."…"

Reviewed on Jan 18, 2021

Hyannis Plaza Hotel
Heritage House Hotel
Heritage House Hotel
2.5 out of 5
259 Main Street, Hyannis, MA
Free CancellationReserve now, pay when you stay
The price is $89 per night from Jan 23 to Jan 24
3.5/5Good! (998 reviews)
Great Location

"Wonderful, great staff."…"

Reviewed on Oct 19, 2020

Heritage House Hotel
Americas Best Value Inn & Suites Hyannis Cape Cod
Americas Best Value Inn & Suites Hyannis Cape Cod
2 out of 5
206 Main St, Hyannis, MA
Get Rates
3.4/5 (998 reviews)

"Our stay was good. Accessible and clean. My only comment is they should provide coffeemaker and mucrowave every room. Instead of walking to the office to get coffee. And heat food. Thst i would give a 10."…"

Reviewed on Sep 27, 2020

Americas Best Value Inn & Suites Hyannis Cape Cod
See all 4451 properties in Main Street Hyannis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top things to do in Main Street Hyannis

Image for Ultimate Self-Driving Tour of Cape Cod and Provincetown

Ultimate Self-Driving Tour of Cape Cod and Provincetown

$10
Per adult
Ultimate Self-Driving Tour of Cape Cod and Provincetown
Image for 1-Day Boston+Cap Cod Tour (Boston departure) BC1

1-Day Boston+Cap Cod Tour (Boston departure) BC1

$65
Per adult
1-Day Boston+Cap Cod Tour (Boston departure) BC1
Image for Wine and Wine Jelly-Sauce Tasting on Plymouth Bay

Wine and Wine Jelly-Sauce Tasting on Plymouth Bay

$7
Per adult
100% of travellers recommend
Wine and Wine Jelly-Sauce Tasting on Plymouth Bay
See all activities in Main Street Hyannis

What are the advantages of a road trip to Main Street Hyannis?

There’s nothing quite like a Main Street Hyannis road trip. And Expedia makes it easy for you to turn all those road trip ideas into reality. You can find cheap deals on hotels in Main Street Hyannis or bundle your hotels with car rentals to save even more. With our Main Street Hyannis packages, you’ll find hitting the highway for that road trip adventure is more affordable than ever.  

How to plan a road trip to Main Street Hyannis?

Planning a road trip can feel daunting, especially when you’ll be making multiple bookings for your itinerary. But you can find car rentals in Main Street Hyannis and low rates on hotels all in one place— Expedia. How you plan your road trip depends on what’s important to you. People love to take road trips to experience the great outdoors, bond with friends or family and see more of the world. When planning, bundle your car rental and hotel into one discounted package to maximize savings on both. Or, leave room for spontaneity, booking what you need when you need it with our last-minute deals.  

What to do on a road trip to Main Street Hyannis?

When taking a road trip adventure, it’s best to plan how you want to spend your time on your road trip itinerary. We don’t want you to miss out on any of the best things to do in Main Street Hyannis. You can book all the road trip activities on your Main Street Hyannis wishlist, and even plan activities along your route as well.  

How to rent a car for a road trip?

For an epic road trip, you'll need the perfect car. Renting a car for a road trip is the best option that doesn’t put miles or strain on your vehicle, and especially when it's also so affordable. Because when you book on Expedia, it doesn't need to be expensive. You can pick up a cheap car rental and head out to one of these incredible vacation rentals in Main Street Hyannis. And when you bundle car rentals with hotel stays, you'll save even more on each part of your journey.

Frequently asked questions

How much does a Main Street Hyannis vacation package cost?
From as little as $297. Yes, you read that right. Our Main Street Hyannis vacation packages are the quickest way to make your budget last longer. Bundle your preferred flights, hotels and rental car and discover this wonderful destination.
If I'm not able to travel, can I cancel my Main Street Hyannis vacation package?
Yes, you can. We realize even the best-laid plans can fail, so we’re here to help if you have to make changes to your Main Street Hyannis vacation package. You may be able to change or cancel your itinerary for free if you’ve booked in the last 24 hours. Your airline, hotel or car rental company may charge you a fee if your booking was made more than 24 hours ago. Look up our Customer Service Portal for further information. Also, check your itinerary for the nitty-gritty on change fees.
How do I get a cheap travel package to Main Street Hyannis?
Combine your hotels and flights, throw in extras such as tours, and save up to $583. A Main Street Hyannis vacation package makes traveling on a budget a walk in the park. You won’t just score awesome discounts on your getaway — you’ll have lots of choice too. When you book through Expedia, you can choose from more than 550 air carriers and 1,000,000 properties worldwide. Your next grand adventure begins right here, right now!
Where should I stay in Main Street Hyannis?
A trip to Main Street Hyannis isn’t complete without seeing John F. Kennedy Hyannis Museum, Cape Cod Baseball Hall of Fame and Cape Cod Carousel. Spend your nights close to these popular sights and make sightseeing simple.
What are the top hotels in Main Street Hyannis?
If it’s your first time staying in Main Street Hyannis, book a room at Heritage House Hotel or Hyannis Inn. Both hotels offer comfortable beds and are popular options with many travelers.
When is the best time of year to visit Main Street Hyannis?
is considered the high season in Main Street Hyannis, while is usually quieter. If you’re on the hunt for a fantastic deal on your getaway, consider the month of . Keep in mind that is typically the priciest time to visit.
How far in advance should I book my Main Street Hyannis vacation?
Search Expedia to compare international fares as soon as you know your travel dates. In most cases, you can purchase a ticket up to a year before departure. If you can’t find your preferred air carrier, or you’re booking late, don’t despair. The lowest prices to Main Street Hyannis sometimes emerge within weeks of departure.
What does an Expedia Main Street Hyannis travel package include?
Hotels, car rentals and flights — we connect you to all the best deals. All you’ll have to do is pick and choose your ideal combination. Once you’ve made your booking, you can add on the exciting stuff like day tours and sightseeing activities. Our travel packages make it simple to create an amazing Main Street Hyannis trip.
What should I know before booking a Main Street Hyannis travel package?
A package can be cheaper than separately booking all you need for your escape. For example, bundle your hotels, flights and rental cars and save a packet. No matter your vacation goals, you’ll find a package that’s perfect for you.
Does Expedia offer Book Now, Pay Later Main Street Hyannis vacation packages?
If you prefer to split the price of your activities and hotel over numerous installments, Expedia is here to help. Paying the full amount for your journey upfront isn’t always the best way to budget for your vacation, so we’ve teamed up with online lender Affirm to give you financial freedom. Book Now, Pay Later and remove the stress of saving to travel.
Can I choose my airline with a Main Street Hyannis Expedia vacation package?
Yes — that’s the beauty of an Expedia package. You’re the boss! We have access to more than 550 partner airlines all over the world, so you have loads of choice when planning your Main Street Hyannis trip.

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