Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Save up to $603 by booking Flight + Hotel.

Search 321,000 hotels and 400 airlines worldwide.

Get the price Guarantee available for your trip.


Main Street Hyannis

Main Street Hyannis is 9 miles from the center of Cape Cod.

Packages in Main Street Hyannis

Expedia has lodging and flight deals that are waiting for you. Getting your desired flights and lodgings are the ingredients for a good vacation. Combining them together with us into a single package deal is a recipe for success that leaves out the stress and saves money. While you are staying in Main Street Hyannis, spoil yourself with your extra cash.

Savings of about $603 are available to smart travelers who secure a package deal.

We enjoy making going on a vacation effortless when you use our extensive range of about 400 airline partners and 321,000 worldwide hotels.

The super prices at Expedia are guaranteed to satisfy!

If you change your travel plans we will honor your cancellation request with no extra fee, on nearly all bookings.

Main Street Hyannis Vacation Packages

To get there from Barnstable Municipal Airport, pick up your bags and go 1 mile to the south.

Warm up with a few nearby attractions, including Cultural Center of Cape Cod and Werner Schmidt Observatory. Try not to ignore Bass River Sports World and ZooQuarium. More neighboring communities, like Hyannis and Hyannis Port, are also worth exploring.

Cape Cod Museum of Art is worth going to, and it's close to the city's heart.

Take a stroll through the excellent collections and see if you can catch a guided tour at Captain Bangs Hallet House Museum, Edward Gorey House, Cape Cod Baseball Hall of Fame and Coast Guard Heritage Museum.

Secure seats for a live performance at one of the popular local venues. Cape Cod Melody Tent and Barnstable Performing Arts Center are top options.

Challenge your buddies to a game of golf over at Twin Brooks Golf Course, Bayberry Hills Golf Course and Hyannis Golf Course. And afterwards, go to the nineteenth hole for an ice cold beer.

When you feel like treating the little travelers, Cape Cod Carousel and Sturgis Library are just the ticket.

Get going to Cape Cod Inflatable Park, Putter's Paradise Miniature Golf, Wild Animal Lagoon and Pirate's Cove Mini Golf when the children are bored and restless. Let them burn some energy so you can all rest easy.

Get outside and breathe in the clean air at one of the nature areas, including Lewis Bay, Barnstable Harbor and Hyannis Harbor.

Listen to the seabirds, skim stones in the shallows and watch the waves roll in at Englewood Beach, Craigville Beach, Seagull Beach and Gray's Beach.

Stroll by the trees, get stuck into a good book and relax in the sunshine at Dennis Pond Conservation Area, Long Pasture Wildlife Sanctuary and Veterans Memorial Park.

Step back through the mists of time at John F. Kennedy Memorial, St. Francis Xavier Church, Barnstable Old Gaol and Coast Guard Heritage Museum. These historic sites have plenty of intriguing stories to tell.

The sacred places, such as St Mary's Episcopal Church and West Parish Meetinghouse, give you the chance to ponder in a peaceful setting.

Accommodation in Main Street Hyannis

When a place is as popular as Main Street Hyannis, it should come as no surprise that there is a comprehensive range of hotel and apartment options to select from. You'll find 70 Main Street Hyannis hotels on Expedia's global hotel booking pages.

The following Main Street Hyannis hotels are worth checking out, the Red Jacket Beach Resort and Green Harbor Resort


Top Hotel Deals

See all 415 Hotels in Main Street Hyannis
$80
Heritage House Hotel

Heritage House Hotel

259 Main Street, Hyannis
3.5
of 5, from 1,436 reviews
3.0 out of 5.0
Americas Best Value Inn and Suites Hyannis/Cape Cod

Americas Best Value Inn and Suites Hyannis/Cape Cod

206 Main St, Hyannis
3.3
of 5, from 969 reviews
2.5 out of 5.0

Located in Main Street Hyannis, this hotel is within a 10-minute walk of John F. Kennedy Hyannis Museum, Cape Cod Baseball Hall of Fame, and Hyannis Harbor. Cape Cod Carousel and Wild Animal Lagoon are also within 15 minutes.

$80
International Inn

International Inn

662 Main Street, Hyannis
3.0
of 5, from 1,602 reviews
3.0 out of 5.0

Located in Main Street Hyannis, this luxury hotel is within a 10-minute walk of Cape Cod Carousel, St. Francis Xavier Church, and Twin Brooks Golf Course. Cape Cod Melody Tent and Cape Cod Baseball Hall of Fame are also within 10 minutes.

Cape Cod Inn

Cape Cod Inn

447 Main St, Hyannis
3.5
of 5, from 436 reviews
2.5 out of 5.0

Located in Main Street Hyannis, this motel is steps from Cape Cod Baseball Hall of Fame and John F. Kennedy Hyannis Museum. Cape Cod Carousel and St. Francis Xavier Church are also within 5 minutes.

$101
Doubletree by Hilton Cape Cod - Hyannis

Doubletree by Hilton Cape Cod - Hyannis

287 Iyannough Rd, Hyannis
4.2
of 5, from 357 reviews
4.0 out of 5.0

Situated near the airport, this hotel is within 1 mi (2 km) of John F. Kennedy Hyannis Museum, Cape Cod Baseball Hall of Fame, and Hyannis Harbor. John F. Kennedy Memorial and Barnstable Performing Arts Center are also within 3 mi (5 km).

$145
Chatham Wayside Inn

Chatham Wayside Inn

512 Main St, Chatham
4.4
of 5, from 30 reviews
4.0 out of 5.0

Situated near the beach, this inn is within a 15-minute walk of Chatham Windmill, Monomoy Theatre, and Chatham Seaside Links. Chatham Railroad Museum and Veterans Field are also within 15 minutes.

$119
Cape Codder Resort and Spa

Cape Codder Resort and Spa

1225 Iyannough Rd, Hyannis
3.9
of 5, from 628 reviews
3.5 out of 5.0

Situated near the airport, this spa resort is 1.2 mi (2 km) from Hyannis Golf Course and within 3 mi (5 km) of Coast Guard Heritage Museum and Barnstable Old Gaol. Barnstable Performing Arts Center and Cape Cod Carousel are also within 3 mi (5 km).

$60
Cape Point Hotel

Cape Point Hotel

476 Main St, West Yarmouth
3.6
of 5, from 1,033 reviews
3.5 out of 5.0

Located in Yarmouth, this hotel is within 1 mi (2 km) of Cape Cod Inflatable Park, ZooQuarium, and Englewood Beach. Pirate's Cove Mini Golf and Putter's Paradise Miniature Golf are also within 2 mi (3 km).

Top Flight + Hotel Deals

Top Deals on Flights

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.