Title: $49 Car Rental Main Street Hyannis, MA - Expedia.com [Hyannis Travel Guide](https://expedia.com/Hyannis.dx1544)[Main Street Hyannis Hotels](https://expedia.com/Main-Street-Hyannis-Hotels.0-l6287458-0.Travel-Guide-Filter-Hotels)[Flights to Hyannis](https://expedia.com/Cheap-Flights-To-Hyannis.d1544.Travel-Guide-Flights)[Things to do in Hyannis](https://expedia.com/Things-To-Do-In-Hyannis.d1544.Travel-Guide-Activities)[Main Street Hyannis Vacations](https://expedia.com/Main-Street-Hyannis-Hyannis.d6287458.Vacation-Attraction) ![](https://images.trvl-media.com/place/6287458/3dc1167b-95a0-4295-b537-9961081522cb.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # $49 Car Rental Main Street Hyannis, MA ## Search and Compare from Car Companies in Main Street Hyannis ## Featured car rental suppliers Compare from agencies ![car suppliers logo](https://forever.travel-assets.com/flex/flexmanager/images/2022/02/16/car-suppliers-logo-desktop.jpg) - ![protection illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__protection.svg) ### Change your mind Penalty-free cancellation on many/select car rentals - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Treat yourself One Key members save 10% or more on over 1 million car rentals [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![package illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__package.svg) ### Shop smart Compare car suppliers and package your flight, hotel, and car to save ## Top Car Deals in Main Street Hyannis \* Price found within the past 6 days. Click for updated prices. Thu, Feb 26 - Fri, Feb 27 ### Compact Ford Focus or similar - 5 people - Unlimited mileage ![Hertz](//mediaim.expedia.com/cars/logos/ZE.png) Boston, Massachusetts, USA ![Ford Focus](//mediaim.expedia.com/cars/40/b0b0d176-5217-4b23-9e8d-d49ee10835ec.jpg) #### $49 includes taxes & fees $20 per day found 4 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.367380&olon=-71.031200&date1=2/26/2026&date2=2/27/2026&pprfrr=20.0&tprfrr=49.24&cvrfrr=ZE&ctrfrr=CC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22compact%22]) Thu, Feb 26 - Fri, Feb 27 ### Special Managers Special or similar - 4 people - Unlimited mileage ![Dollar](//mediaim.expedia.com/cars/logos/ZR.png) East Boston, Massachusetts, USA ![Managers Special](//mediaim.expedia.com/cars/43/eb66feb7-951f-4cc5-bc22-f50d5dc5457e.jpg) #### $49 includes taxes & fees $20 per day found 4 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.366670&olon=-71.000000&date1=2/26/2026&date2=2/27/2026&pprfrr=20.0&tprfrr=49.28&cvrfrr=ZR&ctrfrr=XX&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22other%22]) Thu, Feb 26 - Fri, Feb 27 ### Economy Chevrolet Spark or similar - 4 people - Unlimited mileage ![Hertz](//mediaim.expedia.com/cars/logos/ZE.png) Boston, Massachusetts, USA ![Chevrolet Spark](//mediaim.expedia.com/cars/40/325297f9-cf83-4ce9-9eb1-a6032b62a34e.jpg) #### $49 includes taxes & fees $20 per day found 4 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.367380&olon=-71.031200&date1=2/26/2026&date2=2/27/2026&pprfrr=20.0&tprfrr=49.24&cvrfrr=ZE&ctrfrr=EC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22economy%22]) Thu, Feb 26 - Fri, Feb 27 ### Midsize Mazda 3 4-door or similar - 5 people - Unlimited mileage ![Hertz](//mediaim.expedia.com/cars/logos/ZE.png) Boston, Massachusetts, USA ![Mazda 3 4-door](//mediaim.expedia.com/cars/40/4d18581d-6ea9-41f9-8ee1-b30c8c1d3cfc.jpg) #### $52 includes taxes & fees $22 per day found 4 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.367380&olon=-71.031200&date1=2/26/2026&date2=2/27/2026&pprfrr=22.0&tprfrr=51.82&cvrfrr=ZE&ctrfrr=IC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22midsize%22]) Thu, Feb 26 - Fri, Feb 27 ### Standard Chevrolet Cruze or similar - 5 people - Unlimited mileage ![Thrifty](//mediaim.expedia.com/cars/logos/ZT.png) East Boston, Massachusetts, USA ![Chevrolet Cruze](//mediaim.expedia.com/cars/45/90787807-9af7-4241-9b58-a7795543b073.jpg) #### $53 includes taxes & fees $23 per day found 4 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.366670&olon=-71.000000&date1=2/26/2026&date2=2/27/2026&pprfrr=22.99&tprfrr=53.12&cvrfrr=ZT&ctrfrr=SC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22standard%22]) Thu, Feb 26 - Fri, Feb 27 ### Fullsize Chevrolet Malibu or similar - 5 people - Unlimited mileage ![Hertz](//mediaim.expedia.com/cars/logos/ZE.png) Boston, Massachusetts, USA ![Chevrolet Malibu](//mediaim.expedia.com/cars/40/1290a4c0-23ef-46ad-b34d-e3f26aab3b6c.jpg) #### $54 includes taxes & fees $24 per day found 4 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.367380&olon=-71.031200&date1=2/26/2026&date2=2/27/2026&pprfrr=24.0&tprfrr=54.4&cvrfrr=ZE&ctrfrr=FC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22fullsize%22]) Thu, Feb 26 - Fri, Feb 27 ### Premium Pickup Regular Cab Ford F150 or similar - 5 people - Unlimited mileage ![Alamo](//mediaim.expedia.com/cars/logos/AL.png) East Boston, Massachusetts, USA ![Ford F150](//mediaim.expedia.com/cars/6/a9d17556-0fbf-437d-906c-b0f1dd727f74.jpg) #### $70 includes taxes & fees $36 per day found 4 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.367090&olon=-71.030620&date1=2/26/2026&date2=2/27/2026&pprfrr=35.97&tprfrr=69.61&cvrfrr=AL&ctrfrr=PP&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22pickup%22]) Thu, Feb 26 - Fri, Feb 27 ### Mini Van Chrysler Pacifica or similar - 7 people - Unlimited mileage ![Dollar](//mediaim.expedia.com/cars/logos/ZR.png) East Boston, Massachusetts, USA ![Chrysler Pacifica](//mediaim.expedia.com/cars/43/9c129e79-2a68-4e58-97b3-110d1119e59c.jpg) #### $75 includes taxes & fees $40 per day found 4 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.366670&olon=-71.000000&date1=2/26/2026&date2=2/27/2026&pprfrr=40.0&tprfrr=75.02&cvrfrr=ZR&ctrfrr=MV&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22minivan%22]) Tue, Feb 24 - Wed, Feb 25 ### Standard Elite Special Ford Mustang Mach-E or similar - 5 people - Unlimited mileage ![Budget](//mediaim.expedia.com/cars/logos/ZD.png) Boston, Massachusetts, USA ![Ford Mustang Mach-E](//mediaim.expedia.com/cars/39/9eb70d2f-e3e7-4e36-9e24-1505e077c35a.jpg) #### $96 includes taxes & fees $56 per day found 13 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.366776&olon=-71.030707&date1=2/24/2026&date2=2/25/2026&pprfrr=55.99&tprfrr=96.25&cvrfrr=ZD&ctrfrr=RX&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22standard%22]) Thu, Feb 26 - Fri, Feb 27 ### Luxury SUV Lincoln Navigator Infiniti QX80 or similar - 7 people - Unlimited mileage ![Alamo](//mediaim.expedia.com/cars/logos/AL.png) East Boston, Massachusetts, USA ![Lincoln Navigator Infiniti QX80](//mediaim.expedia.com/cars/6/282223a8-820d-4aa8-a2c0-6ad5183d79be.jpg) #### $112 includes taxes & fees $71 per day found 4 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.367090&olon=-71.030620&date1=2/26/2026&date2=2/27/2026&pprfrr=71.48&tprfrr=111.52&cvrfrr=AL&ctrfrr=LF&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22suv%22]) Tue, Feb 24 - Wed, Feb 25 ### Luxury Elite Genesis G80E or similar - 5 people - Unlimited mileage ![Budget](//mediaim.expedia.com/cars/logos/ZD.png) Boston, Massachusetts, USA ![Genesis G80E](//mediaim.expedia.com/cars/39/8cfce1f9-4e0c-482d-8c45-0b135c4d0b15.jpg) #### $140 includes taxes & fees $90 per day found 13 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.366776&olon=-71.030707&date1=2/24/2026&date2=2/25/2026&pprfrr=89.99&tprfrr=139.5&cvrfrr=ZD&ctrfrr=WC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22luxury%22]) ### Don't see what you're looking for? See all car rentals in Main Street Hyannis [View all cars](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Main%20Street%20Hyannis,%20Hyannis,%20Massachusetts,%20United%20States%20of%20America&dpln=6287458&date1=2/28/2026&date2=3/2/2026&crfrr=defaultFlex&SearchType=Place) Lowest prices found within the past 4 hours. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=CTG_SPRING_PROMO_6287458) ## Frequently asked questions ### How much is a rental car per day in Main Street Hyannis? ### What happens if I need to cancel my Main Street Hyannis car reservation? ### Where can I go on a road trip from Main Street Hyannis? > - Head to Providence for a fun-filled sightseeing experience. Approximately 60 miles from Main Street Hyannis, it has lots of amazing attractions, including Roger Williams Park Zoo. > - Why not see all that's on offer in Hartford too? Major attractions in this vibrant city include Mark Twain House & Museum. Hartford is 120 miles from Main Street Hyannis. > - Head to Battery Park to feel grounded in nature. Pack a picnic to enjoy or just recharge your batteries in the fresh air. From Main Street Hyannis, it's about 210 miles away. ### How do I find the best car rental deals in Main Street Hyannis with Expedia? ### How old do you have to be to rent a car in Main Street Hyannis? ### What do you need to rent a car in Main Street Hyannis? ### What is the cheapest car rental in Main Street Hyannis? ### Can I rent a car for a month or longer in Main Street Hyannis? ### Where can I find a Main Street Hyannis car rental if I am younger than 25? ### What insurance should I choose for my car rental in Main Street Hyannis? ## Car Rental Information | Popular car types | [SUV](https://www.expedia.com/lp/b/car-rental/suv?rfrr=car.table.SUV), [Full Size](https://www.expedia.com/lp/b/car-rental/fullsize?rfrr=car.table.FullSize), [Economy](https://www.expedia.com/lp/b/car-rental/economy?rfrr=car.table.Economy) | | ------------------------------------------------ | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Car suppliers available | | | Our best deal of the day | $49 | | Our second best deal of the day | $52 | | Our third best deal of the day | $53 | | From the airport to your hotel | [Airport Transportation](https://www.expedia.com/ground-transfers?rfrr=car.table.AirportTransportation) | | From popular domestic and international airports | [Airport Car Rentals](https://www.expedia.com/lp/b/car-rental/airport) | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [Cape Cod Hotels ](https://www.expedia.com/Cape-Cod-Hotels.d180061.Travel-Guide-Hotels) - [Hyannis Hotels ](https://www.expedia.com/Hyannis-Hotels.d1544.Travel-Guide-Hotels) - [Cheap Hotels in Hyannis ](https://www.expedia.com/Hyannis-Hotels-Cheap-Hotels.0-0-d1544-tCheapHotels.Travel-Guide-Filter-Hotels) - [Oceanfront Hotels in Hyannis ](https://www.expedia.com/Hyannis-Hotels-Oceanfront-Hotels.0-0-d1544-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Hyannis ](https://www.expedia.com/Hyannis-Hotels-Pet-Friendly-Hotel.0-0-d1544-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Hotels near John F. 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