Mesquite Vacation Rentals

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Our top choices for Mesquite vacation rentals

Vacation Home in Northwest El Paso

10.0 out of 10, Exceptional, (13)
"The house was very nice cozy for the size of my family. Everything was perfect. The checkin was very smooth and has all the amenities. I really enjoyed the stay here. "
United States
Nisar A.
$253 nightly
The price is $266
Dec 11 - Dec 12
Total with taxes and fees
★ 1-10-Sunland, WEST, Great for families & long stays, Pet friendly ★

Vacation Home in Las Cruces

2.0 star property
9.6 out of 10, Exceptional, (11)
"Nice and comfortable "
United States
Ian G.
$162 nightly
The price is $175
Dec 16 - Dec 17
Total with taxes and fees
Las Cruces - Modern 3BR Near Downtown, Mesilla, White Sands + Backyard Oasis

Vacation Home in Las Cruces

10.0 out of 10, Exceptional, (21)
"This clean, cool and comfortable home was the perfect overnight spot for my family and our dog as we drove across the country. This lovely home is in a brand new neighborhood that was very quiet and peaceful. Nicely appointed and very comfy beds!"
United States
Kimberly P.
$253 nightly
The price is $269
Dec 14 - Dec 15
Total with taxes and fees
Southwest Gem just minutes from White Sands National Park

Vacation Home in El Paso

10.0 out of 10, Exceptional, (16)
"We have stayed here twice already, my daughter and her family & me & my husband. It’s very comfortable & plenty of room! Highly recommend!"
United States
Gloria L.
$392 nightly
The price is $412
Dec 11 - Dec 12
Total with taxes and fees
Scenic view Spacious Home

Vacation Home in Northwest El Paso

10.0 out of 10, Exceptional, (13)
"Place was great, owner communicated well "
United States
Cody B.
$401 nightly
The price is $422
Jan 5 - Jan 6, 2026
Total with taxes and fees
Cozy and Luxe Retreat: Pool and Stunning Views! Family-Friendly

Villa in Northwest El Paso

9.2 out of 10, Wonderful, (20)
"Cristina was a great host! She worked with all the accommodations we needed and was extremely attentive. We were able to host our family and friends for a small wedding and it was so beautiful in the backyard. A resort-style backyard that we used every part of! "
United States
Ruth C.
$938 nightly
The price is $987
Dec 11 - Dec 12
Total with taxes and fees
***MTV Rented*** Million Dollar Mansion

Apartment in Mesilla

2.0 star property
10.0 out of 10, Exceptional, (21)
"Beautiful, peaceful place!"
United States
Dave S.
Josefina's King Suite in Historic Old Mesilla Plaza.

Apartment in Angel's Triangle

2.0 out of 10, (1)
"This property has a homeless encampment attached to the front of the building. The neighborhood matches that. We did not feel safe stayed long enough to find a hotel and reported the situation to Expedia and VRBO. "
United States
Catherine
$119 nightly
The price is $125
Dec 28 - Dec 29
Total with taxes and fees
Luxury Apartment Unit 8

Vacation Home in Mesilla

10.0 out of 10, Exceptional, (179)
"I have stayed here before and will again. This place is beautiful and in a great location. It fits perfectly into the area. Just walking in makes you feel comfortable."
United States
Nick E.
Casita Azul, Mesilla Plaza Only Steps Away

Vacation Home in Northeast El Paso

10.0 out of 10, Exceptional, (24)
"Great stay, very clean. Made my stay very wonderful "
United States
Trinidad A.
$265 nightly
The price is $279
Dec 15 - Dec 16
Total with taxes and fees
LUXURY EL PASO THEMED HOME W/ FUTURISTIC SHOWERS

Apartment in Angel's Triangle

7.4 out of 10, Good, (3)
"Host was great at responding. "
United States
kellycr08
$129 nightly
The price is $136
Jan 4 - Jan 5, 2026
Total with taxes and fees
Luxury Apartment Suite 2

Apartment in Angel's Triangle

7.8 out of 10, Good, (43)
"Nice condo, easy check in and out. "
United States
Krystal G.
$92 nightly
The price is $96
Dec 14 - Dec 15
Total with taxes and fees
Luxury Apartment Suite 3

Vacation Home in Northeast El Paso

2.0 star property
$296 nightly
The price is $348
Dec 11 - Dec 12
Total with taxes and fees
El Chuco Home W Pool Pool Table 15 min Downtown

Vacation Home in Northwest El Paso

10.0 out of 10, Exceptional, (17)
"We loved the property "
United States
Myndy G.
$279 nightly
The price is $294
Dec 15 - Dec 16
Total with taxes and fees
Franklin Luxe Oasis with Swimming pool and EV charging.

Vacation Home in Las Cruces

7.8 out of 10, Good, (9)
"Home was very neat and comfortable."
United States
Anonymous traveler
$311 nightly
The price is $353
Dec 11 - Dec 12
Total with taxes and fees
Serene 4-bedroom home in a peaceful neighborhood

Villa in EL PASO

10.0 out of 10, Exceptional, (42)
"It was a nice place."
United States
chris s.
$308 nightly
The price is $324
Dec 16 - Dec 17
Total with taxes and fees
VILLA WITH MASTER SUITE CLOSE TO SHOPPING 4 BR 3BA

Vacation Home in Las Cruces

10.0 out of 10, Exceptional, (24)
"Everything you need, plus more. They are the best hosts!!"
United States
Dominick T.
$1,895 nightly
The price is $2,018
Dec 14 - Dec 15
Total with taxes and fees
60-acre custom home with breathtaking views of city of Las Cruces & Organs!

Vacation Home in El Paso

9.0 out of 10, Wonderful, (4)
"This VRBO was super nice and was in a great area, super close to shopping and restaurants. It also had nice views! It was pretty spacious and very clean. The only problem is the TVs had trouble working, but other than that everything was perfect!"
United States
Kaci M.
$174 nightly
The price is $183
Jan 3 - Jan 4, 2026
Total with taxes and fees
⭐️⭐️⭐️La Casita El Paso West side Buena Vista

Vacation Home in Las Cruces

10.0 out of 10, Exceptional, (34)
"We had a great stay!! Perfect home!! SUPER CLEAN!!! "
United States
Bobby L.
$302 nightly
The price is $343
Jan 7 - Jan 8, 2026
Total with taxes and fees
Yucca House | Views, Jetted Bath, Central Retreat

Vacation Home in Las Cruces

10.0 out of 10, Exceptional, (22)
"We had a wonderful time in the area and the house was great and close to everything "
United States
Ken W.
$137 nightly
The price is $148
Dec 14 - Dec 15
Total with taxes and fees
Unique 1-bedroom casita in Mesilla Park with hot tub
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mesquite Hotel Reviews

Find out more about Mesquite

Everything you need to know about Mesquite vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Mesquite vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Mesquite vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Mesquite vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Mesquite. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Mesquite in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $96 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Mesquite rentals

At Expedia, we put the best Mesquite vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Mesquite rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Mesquite vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Mesquite. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Are there vacation rentals in Mesquite?

Yes, you can find vacation rentals close to popular points of interest in Mesquite, or you can choose a more secluded option if you're looking for a relaxing stay.

What's the top vacation rental in Mesquite?

Las Cruces - Modern 3BR Near Downtown, Mesilla, White Sands + Backyard Oasis: This vacation home rental near Mesquite offers a fireplace, a patio, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a stovetop, and a microwave, so you can cook with friends or family.

What can I see and do in Mesquite?

While exploring the area, visit family-friendly sights like Wet and Wild Water World, or get outside and enjoy nature at Rio Grande. Pan American Center and New Mexico State University are a couple of places you'll find in the larger area.

What are vacation rentals like in Mesquite?

Vacation rentals are private properties you can book for a short or long stay in Mesquite. Vacation rentals feature amenities such as hot tubs, fire pits, and patios to help you enjoy your stay. If you're concerned about cleanliness, vacation rentals can offer a sense of seclusion away from public hotel elevators and lobbies packed with people while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a popular choice for a family getaway.