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Mesquite Vacation Rentals

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Check prices for these dates

In two weeks
Oct 2 - Oct 4
In two months
Nov 13 - Nov 15
In three months
Dec 11 - Dec 13
In four months
Jan 8 - Jan 10

Our top choices for Mesquite vacation rentals

A kitchen with light green cabinets, a stainless steel oven, a microwave, and a sink.

1. 1 bedroom near NMSU. W/D in unit/pets welcome.

1 bedroom near NMSU. W/D in unit/pets welcome.
Las Cruces
10.0 out of 10, Exceptional, (2 reviews)
"This property was a perfect stop over for a couple of nights. What made it so perfect is that we could bring our fur babies with us. We especially appreciated the fenced in back yard. The house itself had all the modern conveniences of home. The fresh eggs and muffins were a wonderful surprise."
United States
Debbie B.
$205 nightly
The price is $230
Sep 17 - Sep 18
Total with taxes and fees
1 bedroom near NMSU. W/D in unit/pets welcome.
A hallway with a white console table, a mirror, decorative wall art, and potted plants.

2. Charming 2-bedroom Casita In Mesilla Park Casita Conway #5

Charming 2-bedroom Casita In Mesilla Park Casita Conway #5
Las Cruces
9.8 out of 10, Exceptional, (10 reviews)
"Amazing place. Perfect for our stay! "
United States
Douglas N.
$145 nightly
The price is $157
Sep 20 - Sep 21
Total with taxes and fees
Charming 2-bedroom Casita In Mesilla Park Casita Conway #5
A building entrance with a wooden door, a brick pathway, and a decorative wreath.

3. Charming Casita in historic Town of Mesilla, NM 2392 Calle de Parian

Charming Casita in historic Town of Mesilla, NM 2392 Calle de Parian
Mesilla
10.0 out of 10, Exceptional, (95 reviews)
"Outstanding. Will definitely stay again."
United States
Glenn N.
$201 nightly
The price is $226
Sep 30 - Oct 1
Total with taxes and fees
Charming Casita in historic Town of Mesilla, NM 2392 Calle de Parian
A dining area with a table set for two, blue upholstered chairs, a yellow chair, and a floral centerpiece.

4. Unique 1-bedroom casita in Mesilla Park with hot tub

Unique 1-bedroom casita in Mesilla Park with hot tub
Las Cruces
9.8 out of 10, Exceptional, (30 reviews)
"Cozy house in a walkable neighborhood."
United States
Barbara U.
$150 nightly
The price is $163
Sep 18 - Sep 19
Total with taxes and fees
Unique 1-bedroom casita in Mesilla Park with hot tub
A living room with a fireplace, a sofa, a coffee table, and a ceiling fan.

5. 2 bd/2bth near NMSU and Memorial Medical Center

2 bd/2bth near NMSU and Memorial Medical Center
Las Cruces
10.0 out of 10, Exceptional, (4 reviews)
"Delightful and felt welcome there. All as promoted and responses were totally on point. Location is comforting as well."
United States
Wendy W.
$246 nightly
The price is $276
Sep 17 - Sep 18
Total with taxes and fees
2 bd/2bth near NMSU and Memorial Medical Center
A modern living room with a fireplace, grey sofa, dining table, and a ceiling fan.

6. Charming 2 bedroom retreat at the end of the street equipped for any length stay

Charming 2 bedroom retreat at the end of the street equipped for any length stay
Las Cruces
10.0 out of 10, Exceptional, (13 reviews)
"Great little spot - close to town but super quiet neighborhood. Would def stay here again"
United States
Heather
$226 nightly
The price is $257
Sep 22 - Sep 23
Total with taxes and fees
Charming 2 bedroom retreat at the end of the street equipped for any length stay
A modern kitchen with white cabinetry, a central island with stools, a stainless steel refrigerator, and a backsplash with a blue and white pattern.

7. 4 Bedroom Contemporary Model Home

4 Bedroom Contemporary Model Home
Las Cruces
9.0 out of 10, Wonderful, (36 reviews)
"Great stay. "
United States
Caroline M.
$232 nightly
The price is $251
Sep 17 - Sep 18
Total with taxes and fees
4 Bedroom Contemporary Model Home
A living room with a sofa, coffee table, and a fireplace.

8. 3 bed 2 bath Hacienda near Downtown and NMSU.

3 bed 2 bath Hacienda near Downtown and NMSU.
Las Cruces
10.0 out of 10, Exceptional, (1 review)
"Such an adorable place to stay! We stopped through for one night on our way to our destination. The beds were comfortable and the house was so unique. We loved the fresh eggs for breakfast!"
United States
Sarah E.
$262 nightly
The price is $296
Sep 17 - Sep 18
Total with taxes and fees
3 bed 2 bath Hacienda near Downtown and NMSU.
A kitchen with wooden cabinets, a stainless steel sink, a microwave, and a stove.

9. Charming 1-bedroom house with WiFi, AC Mesilla Park Las Cruces Casita Conway 2

Charming 1-bedroom house with WiFi, AC Mesilla Park Las Cruces Casita Conway 2
Las Cruces
9.2 out of 10, Wonderful, (16 reviews)
"Great property and host - I wish we had reasons to return to Las Cruces!"
United States
Lori L.
$142 nightly
The price is $154
Sep 17 - Sep 18
Total with taxes and fees
Charming 1-bedroom house with WiFi, AC Mesilla Park Las Cruces Casita Conway 2
A porch with a red door, a bench, and potted plants.

10. Casa Del Sol - Peaceful Retreat In Beautiful Mesilla.

Casa Del Sol - Peaceful Retreat In Beautiful Mesilla.
Mesilla
9.8 out of 10, Exceptional, (36 reviews)
"Very comfortable property in a convenient location with a super nice host - definitely recommend and would stay again!"
United States
Nicole D.
$153 nightly
The price is $165
Oct 17 - Oct 18
Total with taxes and fees
Casa Del Sol - Peaceful Retreat In Beautiful Mesilla.
A bedroom with a bed, a desk, and a chair. There are windows with curtains, a ceiling fan, and a rug.

11. Studio w/queen bed, pets ok, 3 min to Farmer's mkt

Studio w/queen bed, pets ok, 3 min to Farmer's mkt
Las Cruces
10.0 out of 10, Exceptional, (2 reviews)
"Wonderful property. Peace and quiet. Lots of wildlife. Worth the unpaved road to reach the property."
United States
Robert T.
$173 nightly
The price is $194
Sep 17 - Sep 18
Total with taxes and fees
Studio w/queen bed, pets ok, 3 min to Farmer's mkt
A spacious living room with striped sofas, a wooden coffee table, and a ceiling fan.

12. 3/2 near University and Memorial Hospital

3/2 near University and Memorial Hospital
Las Cruces
10.0 out of 10, Exceptional, (5 reviews)
"The view of the mountains is amazing from the deck. We really enjoyed our stay."
United States
Peter E.
$277 nightly
The price is $312
Sep 18 - Sep 19
Total with taxes and fees
3/2 near University and Memorial Hospital
A wardrobe with folded towels, a bottle of lotion, and a trash bin.

13. Payne Place 1

Payne Place 1
Las Cruces
9.4 out of 10, Exceptional, (3 reviews)
"Clean, clean and clean! Great communication "
United States
Diana P.
$226 nightly
The price is $245
Sep 19 - Sep 20
Total with taxes and fees
Payne Place 1
A living room with a grey sofa, patterned cushions, a wooden coffee table, and a floral painting on the wall.

14. 2 bed/1 bath near NMSU, pets welcome

2 bed/1 bath near NMSU, pets welcome
Las Cruces
10.0 out of 10, Exceptional, (7 reviews)
"Host was responsive and worked with me to add an additional day after we arrived. Home is so clean and beautiful, was a great place for my family to relax and unwind halfway through our cross country drive. Would love to stay again when I’m in the area"
United States
Jennifer H.
$204 nightly
The price is $231
Sep 20 - Sep 21
Total with taxes and fees
2 bed/1 bath near NMSU, pets welcome
A pathway leading to a building with a number '2640' on the wall, surrounded by gravel and small plants.

15. Beautiful little Magnolia in Las Cruses

Beautiful little Magnolia in Las Cruses
Las Cruces
8.8 out of 10, Excellent, (5 reviews)
"Quiet Clean comfortable beds at a reasonable price "
United States
Timmi M.
$227 nightly
The price is $246
Sep 23 - Sep 24
Total with taxes and fees
Beautiful little Magnolia in Las Cruses
A door with a purple frame and a decorative floral pattern above it.

16. 2 bed, yard, pet friendly in Historic Mesilla.

2 bed, yard, pet friendly in Historic Mesilla.
Las Cruces
10.0 out of 10, Exceptional, (2 reviews)
"We liked the location and homey feeling. Nice to have a yard and chiminea, though we didn't use it this trip."
United States
Tom K.
$234 nightly
The price is $261
Sep 21 - Sep 22
Total with taxes and fees
2 bed, yard, pet friendly in Historic Mesilla.
A hot tub under a pergola with a clear view of the sky and trees in the background.

17. Pet Friendly - 4BR/2.5BA - Near NMSU, Museums, & Golf

Pet Friendly - 4BR/2.5BA - Near NMSU, Museums, & Golf
Las Cruces
8.4 out of 10, Very good, (10 reviews)
"Hi! We had a great stay—thank you so much for hosting us. The home was clean, comfortable, and had everything we needed. We really appreciated the convenient location and the peaceful environment. We enjoyed our time and would definitely recommend your place to others. Thanks again!"
United States
Ruby D.
$221 nightly
The price is $239
Sep 17 - Sep 18
Total with taxes and fees
Pet Friendly - 4BR/2.5BA - Near NMSU, Museums, & Golf
A modern kitchen with white cabinets, a central island, and a microwave above the sink.

18. Downtown Midcentury Studio+ 3 mins to Farmer`s Mkt

Downtown Midcentury Studio+ 3 mins to Farmer`s Mkt
Las Cruces
10.0 out of 10, Exceptional, (1 review)
"We were unable to actually stay in the apartment since we came down with the flu right before our trip. However, communication with the host was easy, they were very responsive, and I will absolutely stay at one of their properties next time we are in Las Cruces. "
United States
Claire Z.
$182 nightly
The price is $204
Sep 17 - Sep 18
Total with taxes and fees
Downtown Midcentury Studio+ 3 mins to Farmer`s Mkt
An outdoor patio with a pool, a grill, and dining setup.

19. Year Around Heated Pool, Mountain Views, Pets Ok

Year Around Heated Pool, Mountain Views, Pets Ok
Las Cruces
10.0 out of 10, Exceptional, (25 reviews)
"Anna was the most amazing part of the experience. Excellent host. Beautiful property and extremely clean. Would recommend to anyone. The property is so quiet with hardly any traffic but close enough to any store you would need. "
United States
Rachael L.
$405 nightly
The price is $431
Sep 27 - Sep 28
Total with taxes and fees
Year Around Heated Pool, Mountain Views, Pets Ok
A modern kitchen with wooden cabinets, stainless steel appliances, and a marble countertop.

20. Historical 1940s Bungalow Near NMSU & Mesilla

Historical 1940s Bungalow Near NMSU & Mesilla
Las Cruces
$222 nightly
The price is $240
Sep 17 - Sep 18
Total with taxes and fees
Historical 1940s Bungalow Near NMSU & Mesilla
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mesquite Hotel Reviews

Hotel Encanto de Las Cruces

Hotel Encanto de Las Cruces

10/10 Excellent
"Great time there as always!"
Anthony 1-night trip
Posted 2 hours ago
Hotel Encanto de Las Cruces

Find out more about Mesquite

Everything you need to know about Mesquite vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Mesquite vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Mesquite vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Mesquite vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Mesquite. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Mesquite in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $133 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Mesquite rentals

At Expedia, we put the best Mesquite vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Mesquite rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Mesquite vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Mesquite. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Are there vacation rentals in Mesquite?

Yes, you can find vacation rentals close to popular points of interest in Mesquite, or you can choose a more secluded option if you're looking for a relaxing stay.

What's the top vacation rental in Mesquite?

Peaceful 3-bedroom house with swim spa in welcoming El Paso: This vacation home rental near Mesquite is located next to a golf course and has an outdoor pool, a patio, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a selection of games and a hot tub.

What can I see and do in Mesquite?

While exploring the area, visit family-friendly sights like Wet and Wild Water World, or get outside and enjoy nature at Rio Grande. Pan American Center and New Mexico State University are a couple of places you'll find in the larger area.

What are vacation rentals like in Mesquite?

Vacation rentals are private properties you can book for a short or long stay in Mesquite. Vacation rentals feature amenities such as hot tubs, fire pits, and patios to help you enjoy your stay. If you're concerned about cleanliness, vacation rentals can offer a sense of seclusion away from public hotel elevators and lobbies packed with people while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a popular choice for a family getaway.