Mezzocammino Vacations from $773

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Your Mezzocammino Vacation

Our Mezzocammino vacation packages are a speedy and practical way to organize and book your next escape. Uncover the true character of this unique neighborhood without the hassle of organizing it all yourself. Your trip to Mezzocammino wouldn't be complete without stopping by major attractions nearby such as Euroma2, Parco de Medici Golf Club and Vintage Carriage Museum. Expedia can put your travel plans into action. Book your ideal Mezzocammino vacation today.

The Latest Mezzocammino Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Charme Spagna Boutique Hotel

Charme Spagna Boutique Hotel

3 out of 5
Rome City Centre
Save 100% on your flight
Price was $1,200, price is now $773 per person
$773
per person
Jan 20 - Jan 25
found 1 day ago
Roundtrip non-stop flight included
Miami (MIA) to Rome (FCO)
9.2/10 Wonderful! (208 reviews)
The staff was so lovely and polite and really helpful, hotel was clean and everything you needed. Hotel was brilliant location, only thing I would say is taxis and Ubers are a lot cheaper than the transfer service to airport that the hotel offered, but would defo recommend

Reviewed on Dec 4, 2025

Rhinoceros

Rhinoceros

5 out of 5
Rome City Centre
Save 100% on your flight
Price was $2,019, price is now $1,233 per person
$1,233
per person
Jan 18 - Jan 24
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
9/10 Wonderful! (29 reviews)
Everything is excellent

Reviewed on Dec 1, 2025

Relais de la Poste

Relais de la Poste

3 out of 5
Rome City Centre
Save 100% on your flight
Price was $1,523, price is now $942 per person
$942
per person
Jan 11 - Jan 16
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
9.2/10 Wonderful! (612 reviews)
Location is absolutely perfect - great spot for walking everywhere, no need for Taxis at all. Staff incredibly friendly and helpful. Would stay again.

Reviewed on Nov 24, 2025

Hotel Giulietta e Romeo

Hotel Giulietta e Romeo

3 out of 5
Municipio X
Price was $1,232, price is now $777 per person
$777
per person
Feb 24 - Feb 27
found 1 day ago
Roundtrip non-stop flight included
Los Angeles (LAX) to Rome (FCO)
7.2/10 Good! (110 reviews)
Beautiful ride and nice neighbourhood

Reviewed on Aug 5, 2025

Smart Guesthouse

Smart Guesthouse

3 out of 5
Rome City Centre
Save 100% on your flight
Price was $1,330, price is now $854 per person
$854
per person
Feb 2 - Feb 8
found 13 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
9.6/10 Exceptional! (76 reviews)
Great location because of how close it is to the train station, stay was very pleasant. The hotel was super communicative. Would recommend!

Reviewed on Nov 19, 2025

Where to stay in Mezzocammino

Find the best Mezzocammino areas and neighborhoods for the activities you enjoy most. Learn more about Mezzocammino
Via del Corso which includes heritage architecture, heritage elements and street scenes

Rome City Centre

8 out of top 10 points of interest in this area
4.5/5(3,994 area reviews)

Follow in the footsteps of ancient Romans when you tour the Eternal City's most well-known historical sites and see where it started almost 3,000 years ago.

Find hotels in Rome City Centre

Mezzocammino Hotel Deals

Hotel Quirinale

Hotel Quirinale

4 out of 5
Via Nazionale 7 Rome RM
Fully refundableReserve now, pay when you stay
$128 nightly
The price is $158 total per night from Jan 11 to Jan 12
$158 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
8.6/10 Excellent! (1,919 reviews)
The staff was nice, the room was ample and clean. It was perfectly located near the train station and walk about from all main attractions.

Reviewed on Dec 4, 2025

Hotel Quirinale
The Hive Hotel

The Hive Hotel

4 out of 5
Via Torino 6 Rome RM
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $125 total per night from Dec 24 to Dec 25
$125 total
Dec 24 - Dec 25
Total with taxes and fees
9/10 Wonderful! (1,699 reviews)
Quiet comfortable and great location

Reviewed on Dec 4, 2025

The Hive Hotel
Trastevere Roma | UNA Esperienze

Trastevere Roma | UNA Esperienze

4 out of 5
Via Emilio Morosini 27 Rome RM
Fully refundableReserve now, pay when you stay
$201 nightly
The price is $239 total per night from Jan 11 to Jan 12
$239 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
9.2/10 Wonderful! (1,160 reviews)
The hotel facilities are new and the staff are very kind

Reviewed on Dec 1, 2025

Trastevere Roma | UNA Esperienze
See all 15,857 properties in Mezzocammino
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Discover the most popular places to visit in Mezzocammino

Italy featuring a city, night scenes and heritage architecture

Colosseum

4.5/5(6,605 reviews)

A true architectural heavyweight, the 2,000-year-old Colosseum is often considered one of the seven “modern” wonders of the world.

Colosseum
Trevi Fountain showing a fountain, heritage elements and heritage architecture

Trevi Fountain

4.5/5(6,180 reviews)

Rome is a city abundant in world-class water features, but none more stunning, or more famous, than the Trevi Fountain.

Trevi Fountain
Piazza Navona featuring a square or plaza, heritage architecture and skyline

Piazza Navona

4.5/5(4,020 reviews)

The old papal buildings have altered little over the centuries, but still act as an open-air hub for cafés and street entertainers.

Piazza Navona

Things to do

Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

$53
per adult
82% of travellers recommend
Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour
Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica

Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica

$39
per adult
88% of travellers recommend
Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica
Rome Hop-On Hop-Off Big Bus Tour

Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus

$30
per adult
82% of travellers recommend
Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus
See all activities in Rome
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.