Title: Best Perry County, MO Bed and Breakfast from $164 | Expedia.com [Perry County Hotels](https://expedia.com/Destinations-In-Perry-County.d553248635976433261.Hotel-Destinations)[Vacation Rentals in Perry County](https://expedia.com/Destinations-In-Perry-County.d553248635976433261.Vacation-Rental-Destinations)[Car Rentals in Perry County](https://expedia.com/Destinations-In-Perry-County.d553248635976433261.Car-Rental-Destinations)[Perry County Vacations](https://expedia.com/Perry-County.d553248635976433261.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_bundle_and_save.svg) ### Bundle & Save Get more, spend less whenever you see Bundle & Save deals - ![](https://a.travel-assets.com/travel-assets-manager/pictograms-expedia/light__onekey.svg) ### OneKeyCash Earn OneKeyCash on all your eligible bookings - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_ftc.svg) ### Upfront pricing We are not like the others - we include taxes and fees ## Check prices for these dates Next weekend [Feb 20 - Feb 22](https://www.expedia.com/Hotel-Search?regionId=553248635976433261&startDate=2026-02-20&endDate=2026-02-22&adults=2&lodging=BED_AND_BREAKFAST&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Feb 27 - Mar 1](https://www.expedia.com/Hotel-Search?regionId=553248635976433261&startDate=2026-02-27&endDate=2026-03-01&adults=2&lodging=BED_AND_BREAKFAST&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=553248635976433261&startDate=2026-03-13&endDate=2026-03-15&adults=2&lodging=BED_AND_BREAKFAST&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=553248635976433261&startDate=2026-04-10&endDate=2026-04-12&adults=2&lodging=BED_AND_BREAKFAST&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Perry County bed & breakfast ![Exterior](https://images.trvl-media.com/lodging/35000000/34900000/34893300/34893294/a262c28f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Mississippi Room | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/35000000/34900000/34893300/34893294/b9242bc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![New Orleans Room | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/35000000/34900000/34893300/34893294/0af50b09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/35000000/34900000/34893300/34893294/354a7163.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Conner House B&B [](https://www.expedia.com/Chester-Hotels-The-Conner-House-Bed-And-Breakfast.h34893294.Hotel-Information) Prairie du Rocher 10/10 Exceptional (19 reviews) "Wonderful folks that work there. Nice b&b in a quiet , scenic area." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bradley $147 nightly $164 total Feb 17 - Feb 18 Total with taxes and fees [](https://www.expedia.com/Chester-Hotels-The-Conner-House-Bed-And-Breakfast.h34893294.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/35000000/34530000/34529000/34528901/d6ab8f51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/35000000/34530000/34529000/34528901/5b224348.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Romantic Cottage, 1 King Bed, Non Smoking (Indigo Cottage) | Egyptian cotton sheets, premium bedding, pillowtop beds](https://images.trvl-media.com/lodging/35000000/34530000/34529000/34528901/04e4b463.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Cottage, Multiple Beds, Non Smoking (West End Cottage) | Living area](https://images.trvl-media.com/lodging/35000000/34530000/34529000/34528901/b59945fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Makanda Inn [](https://www.expedia.com/Carbondale-Hotels-Makanda-Inn-Cottages.h34528901.Hotel-Information) Makanda 10/10 Exceptional (35 reviews) "I had a great stay - wonderful hosts and yummy breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julie $285 nightly $315 total Feb 12 - Feb 13 Total with taxes and fees [](https://www.expedia.com/Carbondale-Hotels-Makanda-Inn-Cottages.h34528901.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/105000000/104870000/104861900/104861889/4a21c2a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, books](https://images.trvl-media.com/lodging/105000000/104870000/104861900/104861889/faa62473.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/105000000/104870000/104861900/104861889/bafa9f3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/105000000/104870000/104861900/104861889/52f8e913.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Nanny's Place- Cozy Porchview Getaway B&B by Shawnee Hills Wine Trail and Parks [](https://www.expedia.com/Jonesboro-Hotels-Nannys-Place-Back-Home-Getaway-In-The-Heart-Of-Wine-Trails-And-Parks.h104861889.Hotel-Information) Jonesboro 10/10 Exceptional (3 reviews) "Very friendly hosts. Met them and they were a pleasure to interact with. They had one of the most complete array of amenities that we have ever encountered in our trips! We did have some issues with losing TV service on our last night, but I imagine that it was not their fault.All in all a pleasant experience." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Timothy S. [](https://www.expedia.com/Jonesboro-Hotels-Nannys-Place-Back-Home-Getaway-In-The-Heart-Of-Wine-Trails-And-Parks.h104861889.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/122000000/121220000/121213100/121213046/dfef2a1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/122000000/121220000/121213100/121213046/8eebe887.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/122000000/121220000/121213100/121213046/915f3c80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/122000000/121220000/121213100/121213046/9a4aea52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Nanny's Place- Cozy Rustic Getaway B&B by Shawnee Hills Wine Trail and Parks [](https://www.expedia.com/Jonesboro-Hotels-Nannys-Place-Cozy-Rustic-Getaway-BB-By-Shawnee-Hills-Wine-Trail-And-Parks.h121213046.Hotel-Information) Jonesboro 10/10 Exceptional (1 review) "Property is super cute. Check in was easy. Host communicated very quickly. Had everything you would need to stay for an extended period of time. Delicious zucchini bread provided for breakfast. Easy to find. Would definitely stay here again if we are ever back in Southern Illinois." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mandy H. [](https://www.expedia.com/Jonesboro-Hotels-Nannys-Place-Cozy-Rustic-Getaway-BB-By-Shawnee-Hills-Wine-Trail-And-Parks.h121213046.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/109000000/108480000/108477600/108477548/f687f700.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/109000000/108480000/108477600/108477548/a9916bf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/109000000/108480000/108477600/108477548/cc4df203.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/109000000/108480000/108477600/108477548/f914244d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming 1-bedroom B&B with AC, WiFi in historic Cape Girardeau [](https://www.expedia.com/Cape-Girardeau-Hotels-Charming-1-Bedroom-BB-With-AC.h108477548.Hotel-Information) Cape Girardeau [](https://www.expedia.com/Cape-Girardeau-Hotels-Charming-1-Bedroom-BB-With-AC.h108477548.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-02-24&endDate=2026-02-25®ionId=553248635976433261&adults=2&lodging=BED_AND_BREAKFAST&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FPerry-County-Bed-And-Breakfast.d553248635976433261-aaBedAndBreakfast.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FPerry-County-Bed-And-Breakfast.d553248635976433261-aaBedAndBreakfast.Travel-Guide-Accommodation) ## Top Perry County Hotel Reviews ![Drury Inn & Suites Cape Girardeau](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966_y.jpg) ### Drury Inn & Suites Cape Girardeau 10/10 Excellent "From our room, to food; this was one of the best experiences that we’ve had with hotel travel. The breakfast rivaled a restaurant, the evening snacks and beverages were above board. The staff was friendly, the rooms were clean. The location is fantastic with Outback right beside the hotel and shopping and conveniences very close. I would recommend this establishment, we will be staying here again" [](https://expedia.com/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ![Pear Tree Inn Cape Girardeau West](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg) ### Pear Tree Inn Cape Girardeau West 10/10 Excellent "Great " [](https://expedia.com/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Drury Plaza Hotel Cape Girardeau Conference Center](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg) ### Drury Plaza Hotel Cape Girardeau Conference Center 10/10 Excellent "The room was great. The facility was excellent. The people were excellent. Definitely going back." [](https://expedia.com/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Cabin in Southern Illinois - Hot Tub - Romantic Getaway -Shawnee National Forest](https://images.trvl-media.com/lodging/35000000/34340000/34332000/34331993/cb67aaf7_y.jpg) ### Cabin in Southern Illinois - Hot Tub - Romantic Getaway -Shawnee National Forest 10/10 Excellent "Great place for a weekend getaway!" [](https://expedia.com/Jonesboro-Hotels-Cabin-In-Southern-Illinois-Hot-Tub-Romantic-Getaway-Shawnee-National-Forest.h34331993.Hotel-Information) ![Drury Inn & Suites Jackson MO](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d_y.jpg) ### Drury Inn & Suites Jackson MO 10/10 Excellent "Room was very clean. Staff was very knowledgeable and courteous. Excellent staff in every department. " [](https://expedia.com/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Courtyard by Marriott Cape Girardeau Downtown](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/ae49c8da_y.jpg) ### Courtyard by Marriott Cape Girardeau Downtown 10/10 Excellent "Convenient location, clean room, and easy check in/out process. Really cool little downtown." [](https://expedia.com/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) ![The Riverview](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg) ### The Riverview 10/10 Excellent "The hotel was so nice! We planned this trip for my husbands 40th birthday, and I called ahead to see if they did anything for birthdays and they gave us a complementary upgrade on our room. I was taken back on that and thought it was so kind and generous. I wasn’t expecting that - I would have been fine with some cookies and a sign that said happy birthday! We really appreciate everyone and their generosity for us. We definitely will be staying again!!" [](https://expedia.com/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![Days Inn by Wyndham Perryville](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/f6ab26a4_y.jpg) ### Days Inn by Wyndham Perryville 10/10 Excellent "Great people there" [](https://expedia.com/Perryville-Hotels-Days-Inn-By-Wyndham-Perryville.h10352.Hotel-Information) ![Super 8 by Wyndham Perryville](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/f824aec9_y.jpg) ### Super 8 by Wyndham Perryville 10/10 Excellent "Room was clean. Staff went above and beyond. Lots of family in town all stayed here they accommodated us all nicely, let us utilize common areas to be together in the evening. Highly recommend " [](https://expedia.com/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information) ## Find out more about Perry County ## Perry County B&B information | Number of reviews | 57 | | ----------------- | ----- | | Accommodation | 6 B&B | | Lowest Price | $164 | | Highest Price | $315 | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Cabin Rentals in Perryville ](https://www.expedia.com/Perryville-Cabins.d6134448-aaCabins.Travel-Guide-Accommodation) - [Motels in Perryville ](https://www.expedia.com/Perryville-Motels.d6134448-aaMotels.Travel-Guide-Accommodation) - [Apartments in Perryville ](https://www.expedia.com/Perryville-Apartments.d6134448-aaApartments.Travel-Guide-Accommodation) - [Perryville Hotels ](https://www.expedia.com/Perryville-Hotels.d6134448.Travel-Guide-Hotels) - [Historic Hotels in Perryville ](https://www.expedia.com/Perryville-Hotels-Historic-Hotel.0-0-d6134448-tHistoricHotel.Travel-Guide-Filter-Hotels) - 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