Title: Top Perry County Hotels: 2026 Best Hotels in Perry County - Expedia.com [Vacation Rentals in Perry County](https://expedia.com/Destinations-In-Perry-County.d553248635976433261.Vacation-Rental-Destinations)[Car Rentals in Perry County](https://expedia.com/Destinations-In-Perry-County.d553248635976433261.Car-Rental-Destinations)[Perry County Vacations](https://expedia.com/Perry-County.d553248635976433261.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Top Cities in Perry County ![Arched train bridge](https://images.trvl-media.com/place/6134448/9dc94c46-c0ab-4d3f-b5fe-2d6ecd4d81c3.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Perryville [](https://expedia.com/Perryville-Hotels.d6134448.Travel-Guide-Hotels) ## Check prices for these dates Tonight [Apr 9 - Apr 10](https://www.expedia.com/Hotel-Search?regionId=553248635976433261&startDate=2026-04-09&endDate=2026-04-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Apr 10 - Apr 11](https://www.expedia.com/Hotel-Search?regionId=553248635976433261&startDate=2026-04-10&endDate=2026-04-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=553248635976433261&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 17 - Apr 19](https://www.expedia.com/Hotel-Search?regionId=553248635976433261&startDate=2026-04-17&endDate=2026-04-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Perry County hotels ![Exterior](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/469821a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/ab22ad5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/0c87c756.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/1d457549.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Perryville by IHG [](https://www.expedia.com/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information) Perryville 9.2/10 Wonderful (577 reviews) "The hotel and room were very clean. It was in a quiet area. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alice $101 nightly $116 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information) ![Suite, 1 King Bed, Non Smoking (1 Bedroom) | In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/e270ba08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 1 King Bed, Accessible, Non Smoking (Mobility Accessible) | In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/ef8850d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/807f3a4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/504b77a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Perryville [](https://www.expedia.com/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information) Perryville 8.4/10 Very Good (975 reviews) "Great place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Doug $64 nightly $73 total Apr 19 - Apr 20 Total with taxes and fees [](https://www.expedia.com/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information) ![Room, 1 King Bed | Jetted tub](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/6caf4858.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/f6ab26a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/19d8e2e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/e7849830.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Perryville [](https://www.expedia.com/Perryville-Hotels-Days-Inn-By-Wyndham-Perryville.h10352.Hotel-Information) Perryville 6.8/10 (431 reviews) "Parking was easy. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Binggang $68 nightly $77 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/Perryville-Hotels-Days-Inn-By-Wyndham-Perryville.h10352.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/bf2aa006.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily breakfast](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/6b56391d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free rollaway beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/26f852d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/0d3bba3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Perryville I-55 [](https://www.expedia.com/Perryville-Hotels-Quality-Inn.h84949.Hotel-Information) Perryville 6.6/10 (128 reviews) "satisfactory" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric $81 nightly $92 total Apr 15 - Apr 16 Total with taxes and fees [](https://www.expedia.com/Perryville-Hotels-Quality-Inn.h84949.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/127000000/126620000/126617400/126617355/804f0425.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Queen Bed with Sofa bed, Pets Allowed | Interior](https://images.trvl-media.com/lodging/127000000/126620000/126617400/126617355/d395df9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/127000000/126620000/126617400/126617355/9e44784b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/127000000/126620000/126617400/126617355/2cb1c224.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Atrium - A Boutique Hotel [](https://www.expedia.com/Perryville-Hotels-The-Atrium-A-Boutique-Hotel.h126617355.Hotel-Information) Perryville $146 nightly $167 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/Perryville-Hotels-The-Atrium-A-Boutique-Hotel.h126617355.Hotel-Information) ![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/84406cc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![55-inch Smart TV with digital channels, TV, streaming services](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/586044dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![55-inch Smart TV with digital channels, TV, streaming services](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/8010cd32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/0b4f194a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Urban Lofts [](https://www.expedia.com/Perryville-Hotels-Urban-Lofts.h76388000.Hotel-Information) Perryville 9.2/10 Wonderful (17 reviews) "Great place to stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric $283 nightly $324 total Apr 20 - Apr 21 Total with taxes and fees [](https://www.expedia.com/Perryville-Hotels-Urban-Lofts.h76388000.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/43000000/42540000/42533900/42533836/aa5618ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/43000000/42540000/42533900/42533836/e5b0b4ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/43000000/42540000/42533900/42533836/f5ad31e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/43000000/42540000/42533900/42533836/2608ec7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Weber Farm - Enjoy a beautiful 100 acre farm! [](https://www.expedia.com/Bouvet-Island-Hotels-Vrbo-Property.h42533836.Hotel-Information) Frohna 10/10 Exceptional (32 reviews) "We enjoyed the beautiful countryside. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jaymie T. $165 nightly $175 total Apr 29 - Apr 30 Total with taxes and fees [](https://www.expedia.com/Bouvet-Island-Hotels-Vrbo-Property.h42533836.Hotel-Information) ![Outdoor spa tub](https://images.trvl-media.com/lodging/116000000/115020000/115013900/115013833/a61e25be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/116000000/115020000/115013900/115013833/0e3da27b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/116000000/115020000/115013900/115013833/c52128e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/116000000/115020000/115013900/115013833/5cf83987.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hot Tub & Creek Views: Secluded Perryville Cabin [](https://www.expedia.com/Perryville-Hotels-Hot-Tub-Creek-Views-Secluded-Perryville-Cabin.h115013833.Hotel-Information) Perryville 9.8/10 Exceptional (11 reviews) "Host was super helpful and the stay was top notch. What a unique old home to get to stay in!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Drew F. [](https://www.expedia.com/Perryville-Hotels-Hot-Tub-Creek-Views-Secluded-Perryville-Cabin.h115013833.Hotel-Information) ![Private kitchen](https://images.trvl-media.com/lodging/127000000/126620000/126618400/126618348/a7c17063.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/127000000/126620000/126618400/126618348/b3f96c4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/127000000/126620000/126618400/126618348/e0117cab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/127000000/126620000/126618400/126618348/c1e6c8e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Mediterranean House 1858 [](https://www.expedia.com/Perryville-Hotels-The-Mediterranean-House-1858.h126618348.Hotel-Information) Perryville $749 nightly $857 total Apr 13 - Apr 14 Total with taxes and fees [](https://www.expedia.com/Perryville-Hotels-The-Mediterranean-House-1858.h126618348.Hotel-Information) ![Outdoor spa tub](https://images.trvl-media.com/lodging/124000000/123750000/123743600/123743557/5b24ebbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/124000000/123750000/123743600/123743557/a359d1c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/124000000/123750000/123743600/123743557/4df54871.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/124000000/123750000/123743600/123743557/39300184.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Retreat Air - King Bed, Hot Tub & No cleaning fee [](https://www.expedia.com/Perryville-Hotels-Retreat-Air-King-Bed.h123743557.Hotel-Information) Perryville 10/10 Exceptional (3 reviews) "Clean, comfortable bed, very welcoming. Kimberly was an awesome host and provided a home away from home that my wife and I the were looking for. We will stay here again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Zachariah N. $160 nightly $172 total Apr 17 - Apr 18 Total with taxes and fees [](https://www.expedia.com/Perryville-Hotels-Retreat-Air-King-Bed.h123743557.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/107000000/106300000/106298200/106298151/1ceefed0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/107000000/106300000/106298200/106298151/a6f28054.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, bed sheets](https://images.trvl-media.com/lodging/107000000/106300000/106298200/106298151/bd6e4c5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hair dryer, towels](https://images.trvl-media.com/lodging/107000000/106300000/106298200/106298151/b23de329.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TreeLoft at BaseCamp [](https://www.expedia.com/Perryville-Hotels-TreeLoft-At-BaseCamp.h106298151.Hotel-Information) Perryville 10/10 Exceptional (5 reviews) "This place is perfect if you want a private upscale experience that is immersed in natural beauty. The treehouse is luxurious and so comfortable. We loved every minute of our stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) joel r. $503 nightly $529 total Apr 20 - Apr 21 Total with taxes and fees [](https://www.expedia.com/Perryville-Hotels-TreeLoft-At-BaseCamp.h106298151.Hotel-Information) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/116000000/115060000/115053400/115053363/05bee420.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/116000000/115060000/115053400/115053363/642618bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/116000000/115060000/115053400/115053363/21c49afd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/116000000/115060000/115053400/115053363/0452b7b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hot Tub & Creek Views: Secluded Perryville Cabin [](https://www.expedia.com/Perryville-Hotels-Hot-Tub-Creek-Views-Secluded-Perryville-Cabin.h115053363.Hotel-Information) Perryville [](https://www.expedia.com/Perryville-Hotels-Hot-Tub-Creek-Views-Secluded-Perryville-Cabin.h115053363.Hotel-Information) ![4 bedrooms, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96360000/96356100/96356094/cdbfd164.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/97000000/96360000/96356100/96356094/b802a532.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, books, offices](https://images.trvl-media.com/lodging/97000000/96360000/96356100/96356094/b7cdefa3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/97000000/96360000/96356100/96356094/bff0d9fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Peaceful 4BR ranch w/ hot tub, fire pit & quick access to Ste. Genevieve’s wineries & shops. [](https://www.expedia.com/St-Mary-Hotels-Ste-Genevieve-Co-House-W-HOT-TUB.h96356094.Hotel-Information) Saint Mary 9.8/10 Exceptional (8 reviews) "Large space which was great. Big bedrooms. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robin $372 nightly $399 total Apr 29 - Apr 30 Total with taxes and fees [](https://www.expedia.com/St-Mary-Hotels-Ste-Genevieve-Co-House-W-HOT-TUB.h96356094.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/91000000/90680000/90678300/90678286/20dd1e36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/91000000/90680000/90678300/90678286/b7804a7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![WiFi, bed sheets](https://images.trvl-media.com/lodging/91000000/90680000/90678300/90678286/372adb8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/91000000/90680000/90678300/90678286/4caaa116.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Urban Loft #8 METALL · Downtown Urban Loft above Restaurants & Boutiques [](https://www.expedia.com/Perryville-Hotels-Urban-Loft-8-METALL-Downtown-Urban-Loft-Above-Restaurants-Boutiques.h90678286.Hotel-Information) Perryville $185 nightly $213 total Apr 10 - Apr 11 Total with taxes and fees [](https://www.expedia.com/Perryville-Hotels-Urban-Loft-8-METALL-Downtown-Urban-Loft-Above-Restaurants-Boutiques.h90678286.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/91000000/90680000/90678400/90678327/9875051b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/91000000/90680000/90678400/90678327/df31bdf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/91000000/90680000/90678400/90678327/7a3a8bf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/91000000/90680000/90678400/90678327/6d03f6b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Urban Loft #1 RED · Urban Loft Downtown above BrewCo & Restaurant [](https://www.expedia.com/Perryville-Hotels-Urban-Loft-1-RED-Urban-Loft-Downtown-Above-BrewCo-Restaurant.h90678327.Hotel-Information) Perryville 10/10 Exceptional (1 review) "Everything was perfect!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thor L. [](https://www.expedia.com/Perryville-Hotels-Urban-Loft-1-RED-Urban-Loft-Downtown-Above-BrewCo-Restaurant.h90678327.Hotel-Information) ![Private kitchen](https://images.trvl-media.com/lodging/101000000/101000000/100995200/100995105/857f4267.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/101000000/101000000/100995200/100995105/68bbe237.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace](https://images.trvl-media.com/lodging/101000000/101000000/100995200/100995105/228c8d56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/101000000/101000000/100995200/100995105/60656f1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gorgeous, downtown house! [](https://www.expedia.com/Perryville-Hotels-Gorgeous.h100995105.Hotel-Information) Perryville 10/10 Exceptional (1 review) "Our stay was excellent and our host Carisa was a Great person to work with. The house was beautiful. The house worked out great for us. We had 6 people staying and we all had very comfortable beds and our own bathrooms. Great for a large family. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Doyle or Cheryl D. $771 nightly $875 total Apr 13 - Apr 14 Total with taxes and fees [](https://www.expedia.com/Perryville-Hotels-Gorgeous.h100995105.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/124000000/123350000/123344800/123344791/e143b87d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/124000000/123350000/123344800/123344791/c9d339a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/124000000/123350000/123344800/123344791/74592eaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/124000000/123350000/123344800/123344791/a3fe1c03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Downtown Urban Loft above Restaurants [](https://www.expedia.com/Perryville-Hotels-Downtown-Urban-Loft-Above-Restaurants.h123344791.Hotel-Information) Perryville $270 nightly $310 total Apr 30 - May 1 Total with taxes and fees [](https://www.expedia.com/Perryville-Hotels-Downtown-Urban-Loft-Above-Restaurants.h123344791.Hotel-Information) ![House (Multiple Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98556800/98556793/624f311c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (Multiple Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98556800/98556793/ba2dc187.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (Multiple Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98556800/98556793/9b7ed3a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (Multiple Bedrooms) | Front of property](https://images.trvl-media.com/lodging/99000000/98560000/98556800/98556793/6cc73fb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Missouri Castle w/ Private Lake, Pool & 100 Acres! [](https://www.expedia.com/St-Mary-Hotels-Missouri-Castle-W-Private-Lake.h98556793.Hotel-Information) St Mary [](https://www.expedia.com/St-Mary-Hotels-Missouri-Castle-W-Private-Lake.h98556793.Hotel-Information) ![Room](https://images.trvl-media.com/lodging/87000000/86150000/86147100/86147079/a3350ef0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/87000000/86150000/86147100/86147079/2892884d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/87000000/86150000/86147100/86147079/52d00c29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/87000000/86150000/86147100/86147079/bdc5405f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### June Bug's Loft [](https://www.expedia.com/Perryville-Hotels-June-Bugs-Loft.h86147079.Hotel-Information) Perryville 10/10 Exceptional (8 reviews) "Really enjoyed this place right in the heart of it all very easy to walk the town from here will be staying again for sure loved it" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jacqueline H. $110 nightly $118 total Apr 10 - Apr 11 Total with taxes and fees [](https://www.expedia.com/Perryville-Hotels-June-Bugs-Loft.h86147079.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/107000000/106300000/106298200/106298154/6e1ec575.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/107000000/106300000/106298200/106298154/35c9db3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/107000000/106300000/106298200/106298154/83b53dd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/107000000/106300000/106298200/106298154/62a118fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### New! Luxury Meets Nature - TreeRise at BaseCamp [](https://www.expedia.com/Perryville-Hotels-New-Luxury-Meets-Nature-TreeRise-At-BaseCamp.h106298154.Hotel-Information) Perryville 10/10 Exceptional (5 reviews) "Had the best stay. Loved the cozy feel. Loved the hot tub right outside the bedroom. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathleen F. $503 nightly $529 total Apr 23 - Apr 24 Total with taxes and fees [](https://www.expedia.com/Perryville-Hotels-New-Luxury-Meets-Nature-TreeRise-At-BaseCamp.h106298154.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-23&endDate=2026-04-24®ionId=553248635976433261&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Perry-County.d553248635976433261.Hotel-Destinations)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Perry-County.d553248635976433261.Hotel-Destinations) ## Top Perry County Hotel Reviews ![Best Western Saluki Inn](https://images.trvl-media.com/lodging/1000000/120000/119200/119178/43576f21_y.jpg) ### Best Western Saluki Inn 10/10 Excellent "Clean spaces, responsive staff, great breakfast!" [](https://expedia.com/Carbondale-Hotels-Best-Western-Saluki-Inn.h119178.Hotel-Information) ![Pear Tree Inn Cape Girardeau West](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/71011e95_y.jpg) ### Pear Tree Inn Cape Girardeau West 10/10 Excellent "Would stay again when in the area." [](https://expedia.com/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Drury Plaza Hotel Cape Girardeau Conference Center](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/5929e46c_y.jpg) ### Drury Plaza Hotel Cape Girardeau Conference Center 10/10 Excellent "Actually the A/C did not cool as well as I would like. I set it at 68 but it never got below 72." [](https://expedia.com/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Courtyard by Marriott Cape Girardeau Downtown](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/927db718_y.jpg) ### Courtyard by Marriott Cape Girardeau Downtown 10/10 Excellent "The staff was very helpful and friendly. The hotel and the rooms were very clean and smelled so good. Would stay here again " [](https://expedia.com/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/47fa1edf_y.jpg) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau 10/10 Excellent "The rooms were clean, the beds were very comfortable, good view of the surrounding area, breakfast was great. The smell of chlorine in the pool area was overwhelming. " [](https://expedia.com/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ![Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f_y.jpg) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG 10/10 Excellent "The hotel was clean and the room are comfortable. It is located right off the interstate near a lot of restaurants, shopping and large medical facility. " [](https://expedia.com/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ![Home2 Suites by Hilton Carbondale](https://images.trvl-media.com/lodging/23000000/22420000/22413300/22413272/6cc7da21_y.jpg) ### Home2 Suites by Hilton Carbondale 4/10 Poor "The room was clean, but there was definitely some things tbag" [](https://expedia.com/Carbondale-Hotels-Home2-Suites-By-Hilton-Carbondale.h22413272.Hotel-Information) ![The Riverview](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg) ### The Riverview 10/10 Excellent "Very nice people and 1st class accommodations… only very small downside was our riverview room was directly over parking lot but could see river in distance. Very nice stay , though " [](https://expedia.com/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![Quality Inn Cape Girardeau North](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781_y.jpg) ### Quality Inn Cape Girardeau North 8/10 Good "Room was well cleaned. A lot of extras in the room that I didn't expect such as a microwave oven, mini fridge, etc." [](https://expedia.com/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### Top cities in Perry County - [Perryville Hotels ](https://expedia.com/Perryville-Hotels.d6134448.Travel-Guide-Hotels) - [Brazeau Township Hotels ](https://expedia.com/Brazeau-Township-Hotels.d553248635976430617.Travel-Guide-Hotels) - [Frohna Hotels ](https://expedia.com/Frohna-Hotels.d553248634983521632.Travel-Guide-Hotels) ### Hotels near popular Attractions - [Hotels near National Shrine of Our Lady of the Miraculous Medal ](https://expedia.com/National-Shrine-Of-Our-Lady-Of-The-Miraculous-Medal-Hotels.0-l553248621561876731-0.Travel-Guide-Filter-Hotels) - [Hotels near Perryville Country Club ](https://expedia.com/Perryville-Country-Club-Hotels.0-l553248621564822920-0.Travel-Guide-Filter-Hotels) - [Hotels near Missouri's National Veterans Memorial ](https://expedia.com/Missouris-National-Veterans-Memorial-Hotels.0-l620724250067501056-0.Travel-Guide-Filter-Hotels) - [Hotels near Mississippi River ](https://expedia.com/Mississippi-River-Hotels.0-l6209928-0.Travel-Guide-Filter-Hotels) - [Hotels near Shawnee National Forest ](https://expedia.com/Shawnee-National-Forest-Hotels.0-l553248635944113522-0.Travel-Guide-Filter-Hotels) - [Hotels near Southern Illinois University ](https://expedia.com/Southern-Illinois-University-Hotels.0-l6091413-0.Travel-Guide-Filter-Hotels) - [Hotels near Mark Twain National Forest ](https://expedia.com/Mark-Twain-National-Forest-Hotels.0-l553248635976468503-0.Travel-Guide-Filter-Hotels) ### More Accommodation Types in Perry County - [Vacation Homes in Perry County ](https://expedia.com/Perry-County-Private-Vacation-Homes.d553248635976433261-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Cabin Rentals in Perry County ](https://expedia.com/Perry-County-Cabins.d553248635976433261-aaCabins.Travel-Guide-Accommodation) - [Apartments in Perry County ](https://expedia.com/Perry-County-Apartments.d553248635976433261-aaApartments.Travel-Guide-Accommodation) - [Cottages in Perry County ](https://expedia.com/Perry-County-Cottages.d553248635976433261-aaCottages.Travel-Guide-Accommodation) - [Motels in Perry County ](https://expedia.com/Perry-County-Motels.d553248635976433261-aaMotels.Travel-Guide-Accommodation) - [Farmstay in Perry County ](https://expedia.com/Perry-County-Agritourism.d553248635976433261-aaAgritourism.Travel-Guide-Accommodation) - [B&B in Perry County ](https://expedia.com/Perry-County-Bed-And-Breakfast.d553248635976433261-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Lodges in Perry County ](https://expedia.com/Perry-County-Lodges.d553248635976433261-aaLodges.Travel-Guide-Accommodation) - [RV Parks in Perry County ](https://expedia.com/Perry-County-RV-Parks.d553248635976433261-aaRVParks.Travel-Guide-Accommodation) - [Guest Houses in Perry County ](https://expedia.com/Perry-County-Guest-Houses.d553248635976433261-aaGuestHouses.Travel-Guide-Accommodation) - [Aparthotels in Perry County ](https://expedia.com/Perry-County-Apart-Hotels.d553248635976433261-aaApartHotels.Travel-Guide-Accommodation) - [Condo Rentals in Perry County ](https://expedia.com/Perry-County-Condos.d553248635976433261-aaCondos.Travel-Guide-Accommodation) ### Hotels near Perry County Airports - [Cape Girardeau Municipal Airport Hotels ](https://expedia.com/Cape-Girardeau-Municipal-Airport-Hotels.0-aCGI-0.Travel-Guide-Filter-Hotels) - [Veterans of Southern Illinois Airport Hotels ](https://expedia.com/Veterans-Airport-Of-Southern-Illinois-Airport-Hotels.0-aMWA-0.Travel-Guide-Filter-Hotels) ### Explore more hotels - [Holiday Inn Express & Suites Perryville by IHG ](https://expedia.com/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information) - [Super 8 by Wyndham Perryville ](https://expedia.com/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information) - [Days Inn by Wyndham Perryville ](https://expedia.com/Perryville-Hotels-Days-Inn-By-Wyndham-Perryville.h10352.Hotel-Information) - [Drury Plaza Hotel Cape Girardeau Conference Center ](https://expedia.com/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) - [The Riverview ](https://expedia.com/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) - [Drury Inn & Suites Cape Girardeau ](https://expedia.com/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) - [La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau ](https://expedia.com/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) - [Drury Inn & Suites Jackson MO ](https://expedia.com/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) - [Silo Farm Haus- located in the heart of wine country! ](https://expedia.com/Ste-Genevieve-Hotels-Silo-Farm-Haus-Located-In-The-Heart-Of-Wine-Country.h39493801.Hotel-Information) - [Best Western Saluki Inn ](https://expedia.com/Carbondale-Hotels-Best-Western-Saluki-Inn.h119178.Hotel-Information) [See a list of all hotels in Perry County](https://expedia.com/All-Perry-County-Hotels.d553248635976433261.Travel-Guide-City-All-Hotels) ### Expedia's Latest Trends Hotels - [Hotels in Country Club Plaza](https://expedia.com/Country-Club-Plaza-Kansas-City-Hotels.0-n6143482-0.Travel-Guide-Filter-Hotels) - [Best Hotels in St. Charles](https://expedia.com/St-Charles-Hotels.d9786.Travel-Guide-Hotels) - [Hotels in Power and Light District](https://expedia.com/Power-And-Light-District-Kansas-City-Hotels.0-n6162504-0.Travel-Guide-Filter-Hotels) - [Six Flags St. Louis hotels](https://expedia.com/Six-Flags-St-Louis-Hotels.0-l6147083-0.Travel-Guide-Filter-Hotels) - [Pet-friendly Hotels in St. Charles County](https://expedia.com/Destinations-In-St-Charles-County-Pet-Friendly-Hotel.0-0-d553248635083913790-tPetfriendlyHotel.Hotel-Filter-Destinations) - [Hotels in Shannon County](https://expedia.com/Destinations-In-Shannon-County.d553248635976433877.Hotel-Destinations) - [Hotels in Downtown Kansas City](https://expedia.com/Downtown-Kansas-City-Kansas-City-Hotels.0-n6058828-0.Travel-Guide-Filter-Hotels) - [Luxury Hotels in St. Louis County](https://expedia.com/Destinations-In-St-Louis-County-Luxury-Hotel.0-0-d553248635083900521-tLuxuryHotel.Hotel-Filter-Destinations) - [Silver Dollar City hotels](https://expedia.com/Silver-Dollar-City-Hotels.0-l6064111-0.Travel-Guide-Filter-Hotels) - [Best Hotels in Independence](https://expedia.com/Independence-Hotels.d8186.Travel-Guide-Hotels) - [GEHA Field at Arrowhead Stadium hotels](https://expedia.com/GEHA-Field-At-Arrowhead-Stadium-Hotels.0-l6058069-0.Travel-Guide-Filter-Hotels) - [Best Hotels in Chesterfield](https://expedia.com/Chesterfield-Hotels.d9530.Travel-Guide-Hotels) - [Hotels in St. Charles County](https://expedia.com/Destinations-In-St-Charles-County.d553248635083913790.Hotel-Destinations) - [Hotels with a Lazy River in St. Louis County](https://expedia.com/Destinations-In-St-Louis-County-Hotels-With-A-Lazy-River.0-0-d553248635083900521-tHotelswithaLazyRiver.Hotel-Filter-Destinations) - [Hotels in Butler County](https://expedia.com/Destinations-In-Butler-County.d553248635976434259.Hotel-Destinations) - [Fort Leonard Wood hotels](https://expedia.com/Fort-Leonard-Wood-Hotels.0-l553248621562507101-0.Travel-Guide-Filter-Hotels) - [Hotels in Downtown St. Louis](https://expedia.com/Downtown-St-Louis-St-Louis-Hotels.0-n800136-0.Travel-Guide-Filter-Hotels) Flights - [Flights from Benton County](https://expedia.com/lp/flights/553248635976431626/flights-from-benton-county) - [Cheap Flights to St Louis City County](https://expedia.com/Destinations-In-St-Louis-City-County.d553248635976432800.Flight-Destinations) - [Flights from Chariton County](https://expedia.com/lp/flights/553248635976429751/flights-from-chariton-county) - [Flights from Saline County](https://expedia.com/lp/flights/553248635976433051/flights-from-saline-county) - [Flights from Madison County](https://expedia.com/lp/flights/553248635976433936/flights-from-madison-county) - [Cheap Flights to Laclede County](https://expedia.com/Destinations-In-Laclede-County.d553248635976434301.Flight-Destinations) Cars - [pickup Car Rentals in St. Louis County](https://expedia.com/Pickup-Car-Rentals-In-St-Louis-County.d553248635083900521-tPickup.Car-Rental-Destination-Class) - [Car rental St. Louis Airport (STL)](https://expedia.com/Car-Rentals-In-Lambert-St-Louis-Intl.d5002323.Car-Rental-Guide) - [Car rental Kansas City Airport (MCI)](https://expedia.com/Car-Rentals-In-Kansas-City-Intl.d4801357.Car-Rental-Guide) - [Car rental Springfield Airport (SGF)](https://expedia.com/Car-Rentals-In-Springfield-Branson-National.d4605779.Car-Rental-Guide) Packages - [St. Louis Zoo](https://expedia.com/St-Louis-Zoo-St-Louis.d502878.Vacation-Attraction) General - [Visit Downtown Kansas City](https://expedia.com/Kansas-City-Downtown-Kansas-City.dx6058828) - [Visit Downtown Branson](https://expedia.com/Branson-Downtown-Branson.dx6336866) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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