--- title: "$82 Cheap flights from Sikeston, MO - Expedia.com" description: "Cheap flights from Sikeston , MO to all destinations. Find best deals for flights from Sikeston , MO from top airlines with great prices at Expedia.com." canonical: "https://www.expedia.com/lp/flights/6058766/flights-from-sikeston" language: en-US market: US currency: USD prices_as_of: 2026-11-13T22:42:37Z --- # $82 Cheap flights from Sikeston, MO [View $82 flight on Sat, Feb 27, 2027](https://www.expedia.com/Flights-Search?leg1=from:STL,to:MCO,departure:2/27/2027TANYT&trip=oneway&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:81.98&airProductToken=AQowCi4IxnISBDI2MzYY8lwgzHAov7OmAzDXtKYDOEVAAFgBagRQQ18xcgdSMjFTTE5UEgwIAhABGAEqAkY5MgAYASIECAEQASgCKAMoBDAN) ## Popular airlines from Sikeston American Airlines United Delta Southwest Airlines Alaska Airlines Frontier Airlines Air Canada ### Be in the know Get alerts if flight prices drop or rise\* ### Book smarter Save up to 30% on select hotels after you book a flight\* ### Earn twice Earn your airline miles on top of our OneKeyCash [Learn about One Key](https://www.expedia.com/welcome-one-key) ## Today's featured flight deals from Sikeston Expedia compares millions of flights to find the best value deals for where you want to go. Nonstop Carry-on included Lower price than typical - [Select American Airlines flight departing on Wed, Nov 25 at 6:00am from St. Louis, returning on Sun, Nov 29 at 6:59am from New York priced at $623](https://www.expedia.com/Flights-Search?leg1=from:STL,to:LGA,departure:11/25/2026TANYT&leg2=from:LGA,to:STL,departure:11/29/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&airOfferToken=v5-sos-d1346669ad69482aa60436241db5ee54-3624-1-st-v5-sos-d1346669ad69482aa60436241db5ee54-3580-1~9.S.1~AQoCCAESBwjUBBABGAEoAlgCcABwAHoDYmZzegNiZnOIAcParmeQAQaQAQSqAQcKA1NUTBAAsgEHCgNOWUMQAA~AQoyCjAIwYIBEgQ0NDg2GPJcIMsBKLCMngMwv42eAzhOQABYAWoETUFJTnIITjBBV1VOTjESCggBEAEYASoCQUEYASIECAEQASgCKAMoBDAL.AQo3CjUIxJgBEgQ0OTM5GMsBIPJcKK-5ngMw37qeAzhYQABYAWoJTUFJTkNMQVNDcghYQVVOQTBNQxIKCAEQARgBKgJETBgBIgQIARABKAIoAygEMAE&medianPrice=943.00&displayPrice=622.79&src=dflp) St. Louis (STL) · New York (LGA) · Nonstop · 3-day trip · just found · 20% less than typical - [Select American Airlines flight departing on Tue, Nov 24 at 6:00am from St. Louis, returning on Sat, Nov 28 at 9:47am from New York priced at $533](https://www.expedia.com/Flights-Search?leg1=from:STL,to:LGA,departure:11/24/2026TANYT&leg2=from:LGA,to:STL,departure:11/28/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&airOfferToken=v5-sos-d80d3de75ad04ee29219e53ac0f143ec-1866-1-st-v5-sos-d80d3de75ad04ee29219e53ac0f143ec-1886-1~8.S.1~AQoCCAESBwjUBBABGAEoAlgCcABwAHoDYmZzegNiZnOIAYvSrmeqAQcKA1NUTBAAsgEHCgNMR0EQAA~AQoyCjAIwYIBEgQ0NDg2GPJcIMsBKJCBngMwn4KeAzhOQABYAWoETUFJTnIITjBBV1VOTjESCggBEAEYASoCQUEYASIECAEQASgCKAMoBDAL.AQo3CjUIxJgBEgQ0OTIyGMsBIPJcKLevngMw7LCeAzhFQABYAWoJTUFJTkJBU0lDcghWQTBOSDNCURIKCAEQARgBKgJETBgBIgQIARABKAIoAygEMAE&medianPrice=786.00&displayPrice=532.79&src=dflp) St. Louis (STL) · New York (LGA) · Nonstop · 4-day trip · just found · 20% less than typical - [Select Southwest Airlines flight departing on Fri, Dec 25 at 5:35am from St. Louis, returning on Mon, Dec 28 at 9:51am from New York priced at $437](https://www.expedia.com/Flights-Search?leg1=from:STL,to:LGA,departure:12/25/2026TANYT&leg2=from:LGA,to:STL,departure:12/28/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&airOfferToken=v5-sos-6735515d982845d6ab3e3edb6c2e9481-1756-1-st-v5-sos-6735515d982845d6ab3e3edb6c2e9481-1650-1~8.S.1~AQoCCAESBwjUBBABGAEoAlgCcABwAHoDYmZzegNiZnOIAZqoqmeQAQ6QAQCqAQcKA1NUTBAAsgEHCgNMR0EQAA~AQovCi0I15wBEgMxNjgY8lwgywEo192gAzDj3qADOEpAAFgBagNXR0FyB0pYTlZTMkYSCggBEAEYASoCV04YASIECAEQASgCKAMoBDAB.AQo3CjUIxJgBEgQ0OTIyGMsBIPJcKPuAoQMwsYKhAzhFQABYAWoJTUFJTkJBU0lDcghYQVdOQTBCQxIKCAEQARgBKgJETBgBIgQIARABKAIoAygEMAE&medianPrice=698.00&displayPrice=436.80&src=dflp) St. Louis (STL) · New York (LGA) · Nonstop · 3-day trip · found 20 hours ago · 25% less than typical - [Select Southwest Airlines flight departing on Wed, Dec 23 at 9:50pm from St. Louis, returning on Sun, Dec 27 at 7:45am from Minneapolis priced at $339](https://www.expedia.com/Flights-Search?leg1=from:STL,to:MSP,departure:12/23/2026TANYT&leg2=from:MSP,to:STL,departure:12/27/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&airOfferToken=v5-sos-3051f0109e35435da0f7182bbf605959-812-1-st-v5-sos-3051f0109e35435da0f7182bbf605959-813-1~8.S.1~AQoCCAESBwjUBBABGAEoAlgCcABwAHoDYmZzegNiZnOIAanZrWeQAQGQAQGqAQcKA1NUTBAAsgEHCgNNU1AQAA~AQowCi4I15wBEgQ0OTY0GPJcIMx8KObOoAMwys-gAzhWQABYAWoDV0dBcgdWQk5WTjJFEgoIARABGAEqAldOGAEiBAgBEAEoAigDKAQwAQ.AQowCi4I15wBEgQzMTMwGMx8IPJcKJn1oAMwgvagAzhJQABYAWoDV0dBcgdJTE5WVjJFEgoIARABGAEqAldOGAEiBAgBEAEoAigDKAQwAQ&medianPrice=622.00&displayPrice=338.80&src=dflp) St. Louis (STL) · Minneapolis (MSP) · Nonstop · 3-day trip · found 4 hours ago · 35% less than typical - [Select Southwest Airlines flight departing on Wed, Dec 23 at 9:50pm from St. Louis, returning on Mon, Dec 28 at 5:32pm from Minneapolis priced at $308](https://www.expedia.com/Flights-Search?leg1=from:STL,to:MSP,departure:12/23/2026TANYT&leg2=from:MSP,to:STL,departure:12/28/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&airOfferToken=v5-sos-af513004a0e449d49cc6cb0bbe2ac2c4-1020-1-st-v5-sos-af513004a0e449d49cc6cb0bbe2ac2c4-1009-1~8.S.1~AQoCCAESBwjUBBABGAEoAlgCcABwAHoDYmZzegNiZnOIAfHarWeQAQOQAQCqAQcKA1NUTBAAsgEHCgNNU1AQAA~AQowCi4I15wBEgQ0OTY0GPJcIMx8KObOoAMwys-gAzhWQABYAWoDV0dBcgdWQk5WTjJFEgoIARABGAEqAldOGAEiBAgBEAEoAigDKAQwAQ.AQpmCjEIwYIBEgQ0NzU1GMx8IK4cKISFoQMw%5FoWhAzhCQABYAWoFQkFTSUNyCFNXQUlZTkJaCjEIwYIBEgQzMjgxGK4cIPJcKN6GoQMwsIehAzhCQAFYAWoFQkFTSUNyCFNXQUlZTkJaEgoIARABGAEqAkFBGAEiBAgBEAEoAigDKAQwCw&medianPrice=552.00&displayPrice=307.60&src=dflp) St. Louis (STL) · Minneapolis (MSP) · Nonstop · 4-day trip · found 4 hours ago · 35% less than typical - [Select Delta flight departing on Tue, Dec 22 at 11:15am from St. Louis, returning on Sat, Dec 26 at 9:51pm from Minneapolis priced at $288](https://www.expedia.com/Flights-Search?leg1=from:STL,to:MSP,departure:12/22/2026TANYT&leg2=from:MSP,to:STL,departure:12/26/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&airOfferToken=v5-sos-7d13572da81f4454a4c36a6dae4bf61d-1341-1~9.S.1~AQoCCAESBwjUBBABGAEoAlgCcAB6A2Jmc4gB242qZ6oBBwoDU1RMEACyAQcKA01TUBAAwAEA~AQo3CjUIxJgBEgQzNzYwGPJcIMx8KMu-oAMws7-gAzhFQABYAWoJTUFJTkJBU0lDcghWRlZTSDNCQwo3CjUIxJgBEgQxNjA5GMx8IPJcKMfwoAMwqPGgAzhFQABYAWoJTUFJTkJBU0lDcghWRldOQTZCQxIKCAEQARgBKgJETBgBIgQIARABKAIoAygEMAE&medianPrice=624.00&displayPrice=287.80&src=dflp) St. Louis (STL) · Minneapolis (MSP) · Nonstop · 4-day trip · found 21 hours ago · 45% less than typical - [Select American Airlines flight departing on Wed, Nov 25 at 10:37am from St. Louis, returning on Sun, Nov 29 at 5:15am from Miami priced at $514](https://www.expedia.com/Flights-Search?leg1=from:STL,to:MIA,departure:11/25/2026TANYT&leg2=from:MIA,to:STL,departure:11/29/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&airOfferToken=v5-sos-944920ca77e941e9a617427bf3fbae5c-2057-1-st-v5-sos-944920ca77e941e9a617427bf3fbae5c-1911-1~9.S.1~AQoCCAESBwjUBBABGAEoAlgCcABwAHoDYmZzegNiZnOIAfnErmeqAQcKA1NUTBAAsgEHCgNNSUEQAA~AQozCjEIwYIBEgQzNjU5GPJcIIwCKMWOngMw6I-eAzhCQABYAWoFQkFTSUNyCFMwQVdVTkJaEgoIARABGAEqAkFBGAEiBAgBEAEoAigDKAQwCw.AQowCi4I15wBEgQyOTM0GIwCIPJcKMe4ngMw8bmeAzhHQABYAWoDV0dBcgdHTE4wVzJHEgoIARABGAEqAldOGAEiBAgBEAEoAigDKAQwAQ&medianPrice=815.00&displayPrice=513.80&src=dflp) St. Louis (STL) · Miami (MIA) · Nonstop · 3-day trip · found 1 hour ago · 25% less than typical - [Select Southwest Airlines flight departing on Sat, Dec 5 at 5:05pm from St. Louis, returning on Fri, Dec 11 at 4:15pm from Miami priced at $309](https://www.expedia.com/Flights-Search?leg1=from:STL,to:MIA,departure:12/5/2026TANYT&leg2=from:MIA,to:STL,departure:12/11/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&airOfferToken=v5-sos-8527d28e5bb74db085722c1c47a258d2-3767-1-st-v5-sos-8527d28e5bb74db085722c1c47a258d2-3768-1~8.S.1~AQoCCAESBwjUBBABGAEoAlgCcABwAHoDYmZzegNiZnOIAcjSrWeQAS2QAS2qAQcKA1NUTBAAsgEHCgNNSUEQAA~AQowCi4I15wBEgQzNzMzGPJcIIwCKImCnwMwqYOfAzhWQABYAWoDV0dBcgdWWk5WSDJHEgoIARABGAEqAldOGAEiBAgBEAEoAigDKAQwAQ.AQowCi4I15wBEgQzNTIyGIwCIPJcKNvEnwMwisafAzhBQABYAWoDV0dBcgdBWE5WUzJHEgoIARABGAEqAldOGAEiBAgBEAEoAigDKAQwAQ&medianPrice=489.00&displayPrice=308.80&src=dflp) St. Louis (STL) · Miami (MIA) · Nonstop · 5-day trip · found 5 hours ago · 25% less than typical - [Select American Airlines flight departing on Fri, Dec 18 at 5:03am from St. Louis, returning on Sun, Dec 27 at 8:27pm from Miami priced at $477](https://www.expedia.com/Flights-Search?leg1=from:STL,to:MIA,departure:12/18/2026TANYT&leg2=from:MIA,to:STL,departure:12/27/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&airOfferToken=v5-sos-5a2e6e202a224b43bcf65e3b680a7641-123-1~9.S.1~AQoCCAESBwjUBBABGAEoAlgCcAB6A2Jmc4gBkJGtZ5ABA6oBBwoDU1RMEAKyAQcKA01JQRAB~AQozCjEIwYIBEgQyOTgxGPJcIIwCKNeOoAMwhpCgAzhCQABYAWoFQkFTSUNyCFNWQUlZU0JaCjMKMQjBggESBDE1ODEYjAIg8lwo1%5FqgAzCT%5FKADOEJAAFgBagVCQVNJQ3IITldGV1pOQloSCggBEAEYASoCQUEYASIECAEQASgCKAMoBDAL&medianPrice=829.00&displayPrice=476.97&src=dflp) St. Louis (STL) · Miami (MIA) · Nonstop · 9-day trip · found 7 hours ago · 30% less than typical Show more deals ## Cheapest flights from Sikeston Prices were available within the past 7 days and start at $82 for one-way flights and $128 for roundtrip, for the period specified. Prices and availability are subject to change. All deals One way Roundtrip [Select Frontier Airlines flight, departing Sat, Dec 5 from St. Louis to Orlando, returning Sat, Dec 12, priced at $128 Found 17 hours ago](https://www.expedia.com/Flights-Search?leg1=from:STL,to:MCO,departure:12/5/2026TANYT&leg2=from:MCO,to:STL,departure:12/12/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:127.96&airProductToken=AQoxCi8IxnISBDI2MzYY8lwgzHAo1IKfAzDsg58DOEVAAFgBagRQQ18xcghaMjFTWFM5QQoxCi8IxnISBDI2MzUYzHAg8lwo8tKfAzCU1J8DOEVAAFgBagRQQ18xcghaMjFTWFM5QRIKCAEQARgBKgJGORgBIgQIARABKAIoAygEMA0) Sat, Dec 5 - Sat, Dec 12 · STL · MCO · Roundtrip [Select Frontier Airlines flight, departing Sat, Feb 27 from St. Louis to Los Angeles, returning Tue, Mar 2, priced at $197 Found 1 day ago](https://www.expedia.com/Flights-Search?leg1=from:STL,to:LAX,departure:2/27/2027TANYT&leg2=from:LAX,to:STL,departure:3/2/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:196.27&airProductToken=AQphCi4IxnISBDQ1NjcY8lwgg2ko%5FrOmAzCVtaYDOEVAAFgBagRQQ18xcgdaMjFTWFMzCi8IxnISBDQzMzkYg2kgi7gBKIm2pgMworemAzhFQAFYAWoEUENfMXIHWjIxU1hTMwpgCi8IxnISBDQzNDYYi7gBIINpKKnTpgMwvtSmAzhFQABYAWoEUENfMXIHWjIxRVhTMwotCMZyEgM2MzAYg2kg8lwo8tumAzD03KYDOEVAAVgBagRQQ18xcgdaMjFFWFMzEgoIARABGAEqAkY5GAEiBAgBEAEoAigDKAQwDQ) Sat, Feb 27 - Tue, Mar 2 · STL · LAX · Roundtrip [Select Frontier Airlines flight, departing Mon, Dec 14 from St. Louis to Miami, returning Sat, Dec 19, priced at $208 Found 1 day ago](https://www.expedia.com/Flights-Search?leg1=from:STL,to:MIA,departure:12/14/2026TANYT&leg2=from:MIA,to:STL,departure:12/19/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:207.34&airProductToken=AQpgCi4IxnISBDQ0NzQY8lwg4Fwo-uSfAzDi5Z8DOEVAAFgBagRQQ18xcgdaMjFOWFMzCi4IxnISBDIyNzIY4FwgjAIonuefAzCc6J8DOEVAAVgBagRQQ18xcgdaMjFOWFMzCmAKLgjGchIEMjQ4MxiMAiDgXCjYmaADMNmaoAM4RUAAWAFqBFBDXzFyB1IyMU9YUDQKLgjGchIENDQ3MxjgXCDyXCjhm6ADMNWcoAM4RUABWAFqBFBDXzFyB1IyMU9YUDQSCggBEAEYASoCRjkYASIECAEQASgCKAMoBDAN) Mon, Dec 14 - Sat, Dec 19 · STL · MIA · Roundtrip [Select Frontier Airlines flight, departing Sat, Feb 20 from St. Louis to Ontario, returning Tue, Feb 23, priced at $214 Found 10 hours ago](https://www.expedia.com/Flights-Search?leg1=from:STL,to:ONT,departure:2/20/2027TANYT&leg2=from:ONT,to:STL,departure:2/23/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:213.95&airProductToken=AQphCi4IxnISBDQ1NjcY8lwgg2konuWlAzC15qUDOEVAAFgBagRQQ18xcgdaMjFTWFMzCi8IxnISBDEyNjEYg2kgrpsBKLTnpQMwxeilAzhFQAFYAWoEUENfMXIHWjIxU1hTMwpgCi8IxnISBDE1MDAYrpsBIINpKIaCpgMwloOmAzhFQABYAWoEUENfMXIHWjIxRVhTMwotCMZyEgM2MzAYg2kg8lwoko2mAzCUjqYDOEVAAVgBagRQQ18xcgdaMjFFWFMzEgoIARABGAEqAkY5GAEiBAgBEAEoAigDKAQwDQ) Sat, Feb 20 - Tue, Feb 23 · STL · ONT · Roundtrip [Select United flight, departing Thu, Jan 7 from Paducah to Fort Lauderdale, returning Mon, Jan 11, priced at $232 Just found](https://www.expedia.com/Flights-Search?leg1=from:PAH,to:FLL,departure:1/7/2027TANYT&leg2=from:FLL,to:PAH,departure:1/11/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:231.29&airProductToken=AQpwCjYI1YIBEgQ1MDU1GI84IIg4KIL0oQMwg%5FWhAzhOQABYAWoKMV9iYXNpY2Vjb3IIS0FBNEpIQlMKNgjVggESBDE5NTYYiDgg5Voo-%5FWhAzCT96EDOE5AAFgBagoxX2Jhc2ljZWNvcghLQUE0SkhCUwpwCjYI1YIBEgQxNzcwGOVaIK4cKJCdogMw5p6iAzhOQABYAWoKMV9iYXNpY2Vjb3IIS0FBNEpIQlMKNgjVggESBDUwNzEYrhwgjzgo95-iAzDQoKIDOE5AAFgBagoxX2Jhc2ljZWNvcghLQUE0SkhCUxIKCAEQARgBKgJVQRgBIgQIARABKAIoAygEMAs) Thu, Jan 7 - Mon, Jan 11 · PAH · FLL · Roundtrip [Select American Airlines flight, departing Mon, Dec 14 from St. Louis to Fort Lauderdale, returning Sat, Dec 19, priced at $239 Found 1 day ago](https://www.expedia.com/Flights-Search?leg1=from:STL,to:FLL,departure:12/14/2026TANYT&leg2=from:FLL,to:STL,departure:12/19/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:238.19&airProductToken=AQpmCjEIwYIBEgQyMzE3GPJcIK4cKNbhnwMwruKfAzhCQABYAWoFQkFTSUNyCE9XQUlYU0JWCjEIwYIBEgQxNDI0GK4cIOVaKKbjnwMw5uSfAzhCQAFYAWoFQkFTSUNyCE9XQUlYU0JWEgoIARABGAEqAkFBGAEiBAgBEAEoAigDKAQwCw) Mon, Dec 14 - Sat, Dec 19 · STL · FLL · Roundtrip [Select Frontier Airlines flight, departing Wed, Dec 2 from St. Louis to New York, returning Wed, Dec 9, priced at $240 Found 8 hours ago](https://www.expedia.com/Flights-Search?leg1=from:STL,to:EWR,departure:12/2/2026TANYT&leg2=from:EWR,to:STL,departure:12/9/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:239.98&airProductToken=AQpfCi0IxnISBDQ0NzQY8lwg4Fwo%5Fd2eAzDh3p4DOEdAAFgBagNFQ09yB0cxNE9YUDQKLgjGchIENDYwMhjgXCDEjQEon-KeAzCp454DOEdAAVgBagNFQ09yB0cxNE9YUDQKXwouCMZyEgQxNjU5GMSNASDMcCiLrJ8DMMGtnwM4UkAAWAFqA0VDT3IHUjIxT1hQNAotCMZyEgQyNjM1GMxwIPJcKJKxnwMwtLKfAzhSQAFYAWoDRUNPcgdSMjFPWFA0EgoIARABGAEqAkY5GAEiBAgBEAEoAigDKAQwAQ) Wed, Dec 2 - Wed, Dec 9 · STL · EWR · Roundtrip [Select American Airlines flight, departing Thu, Feb 25 from St. Louis to Miami, returning Tue, Mar 2, priced at $247 Found 1 day ago](https://www.expedia.com/Flights-Search?leg1=from:STL,to:MIA,departure:2/25/2027TANYT&leg2=from:MIA,to:STL,departure:3/2/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:246.81&airProductToken=AQozCjEIwYIBEgQzMDU0GPJcIIwCKImdpgMwtJ6mAzhCQABYAWoFQkFTSUNyCE9XQUlYU0JYCjIKMAjBggESAzU2NxiMAiDyXCjc0KYDMJvSpgM4QkAAWAFqBUJBU0lDcghPV0FJWFNCWBIMCAEQARgBKgJBQTIAGAEiBAgBEAEoAigDKAQwCw) Thu, Feb 25 - Tue, Mar 2 · STL · MIA · Roundtrip [Select Southwest Airlines flight, departing Wed, Jan 27 from St. Louis to Miami, returning Thu, Feb 4, priced at $247 Found 21 hours ago](https://www.expedia.com/Flights-Search?leg1=from:STL,to:MIA,departure:1/27/2027TANYT&leg2=from:MIA,to:STL,departure:2/4/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:246.82&airProductToken=AQowCi4I15wBEgQzODIyGPJcIIwCKKPTowMwvtSjAzhWQABYAWoDV0dBcgdWWk5XSDJHEgoIARABGAEqAldOGAEiBAgBEAEoAigDKAQwAQ) Wed, Jan 27 - Thu, Feb 4 · STL · MIA · Roundtrip [Select Delta flight, departing Thu, Feb 4 from St. Louis to Miami, returning Wed, Feb 10, priced at $272 Found 1 day ago](https://www.expedia.com/Flights-Search?leg1=from:STL,to:MIA,departure:2/4/2027TANYT&leg2=from:MIA,to:STL,departure:2/10/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:271.41&airProductToken=AQpuCjUIxJgBEgQxMjU3GPJcIOBcKKCwpAMw%5FrCkAzhFQABYAWoJTUFJTkJBU0lDcghWQVdTQTVCQwo1CMSYARIEMTIzNBjgXCCMAijWsaQDMMyypAM4RUABWAFqCU1BSU5CQVNJQ3IIVkFXU0E1QkMSCggBEAEYASoCREwYASIECAEQASgCKAMoBDAB) Thu, Feb 4 - Wed, Feb 10 · STL · MIA · Roundtrip ## How to Find Cheap Flights from Sikeston, MO ### How much is a flight from Sikeston? This week, flights from Sikeston are available between $128 – $272\. ### How to find cheap flights from Sikeston? Expedia makes it easy to compare cheap flights from Sikeston to many destinations. Check out excellent deals on domestic and international flights from Sikeston. Once you select an offer, use our filters and sort by “Price (Lowest)” to see some of the cheapest and suitable options. ### How can I get the best deal on flights from Sikeston? On Expedia, you have some of best airline ticket deals at your fingertips. Whether it’s a beach escape with your partner, a family vacation with your kids, or business trip with colleagues, these low airline ticket prices mean more savings for you. An excellent strategy for finding some of the best deals on flights from Sikeston is to be flexible with your dates. Within each offer, you can compare prices for similar timeframes using our “Show flexible dates” feature. Depending on your destination, direct flights from Sikeston may be more expensive. Airlines with strict bag policies or fees can also impact your costs. ### What is the best airline to fly from Sikeston? At Expedia, we give you all the available options from our reputable partners. Select the airline that best suits your preferences and membership loyalties. You can fly from Sikeston with: Frontier Airlines, United, Southwest Airlines, American Airlines, Delta. ### What is the best month to fly from Sikeston? One of the cheapest times to fly from Sikeston airport(s) is December, based on the current list of flights available now. Prices on plane tickets vary considerably throughout the year due to availability and seasonal demand. ### Are there any last-minute flights from Sikeston? Expedia is the place to find last-minute flights from Sikeston, making it easy for you to compare prices on flights in the near future for different combinations of travel dates and from multiple airlines. We source some of the best deals for you and display some of the best offers available over the next 2 weeks. ### Why book your ticket with Expedia? Booking flights from Sikeston with Expedia is the obvious choice to get low prices, save money, and see more value from every dollar spent. We show you some of the best deals happening right now and provide a vast inventory of airlines and flight routes to choose from, so you can find some of the cheapest flights from Sikeston. You can customize your journey to your timeline, route preferences, budget, rewards programs, and more. ### Can I change/cancel my flight? Some flights can be changed or canceled, but fees and refunds will depend on the unique terms of your flight agreement. Airlines have different rules and restrictions for exchanging or refunding flights. For more information, go to your itinerary or visit our [customer service portal](https://www.expedia.com/service/). We recommend choosing flights with no change fees for the most flexibility. Filter by “Flexible change policies” to see flights with no change fees. ## Travel information | Origin city name | St. Louis | | ------------------------ | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Origin airport | St. Louis Lambert Intl. Airport | | Origin airport IATA code | STL | | Airlines serving | American Airlines, United, Delta, Southwest Airlines, Alaska Airlines, Frontier Airlines, Air Canada, Lufthansa, British Airways, Iberia, KLM, Finnair, Qatar Airways, Air France, Aer Lingus, Japan Airlines, Korean Air, Cathay Pacific, All Nippon Airways, Austrian Airlines, Brussels Airlines, Virgin Atlantic, SAS, LATAM Airlines Group, Turkish Airlines, WestJet, Aeromexico, Copa, Funjet Vacations, Qantas Airways, Emirates, Starlux Airlines, Icelandair, Royal Jordanian, Air New Zealand, Avianca | | Popular airline | American Airlines | | Roundtrip price | $128 | ## Explore a world of travel with Expedia - [Lodging](?equalTargetTab=tab-0) - [Flights](?equalTargetTab=tab-1) - [Packages](?equalTargetTab=tab-2) - [Cars](?equalTargetTab=tab-3) - [Vacation Rentals](?equalTargetTab=tab-4) - [Cape Girardeau Hotels](https://www.expedia.com/Cape-Girardeau-Hotels.d820.Travel-Guide-Hotels) - [Cheap Hotels in Sikeston](https://www.expedia.com/Sikeston-Hotels-Cheap-Hotels.0-0-d6058766-tCheapHotels.Travel-Guide-Filter-Hotels) - 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