Residence Inn Durham McPherson/Duke University Medical Cntr

Hotel with free breakfast, a short walk to Duke University

Choose dates to view prices

Where to?

Dates

November 2025

December 2025

Suite, Multiple Beds, Non Smoking (Mobility Accessible, Tub) | 1 bedroom, in-room safe, desk, laptop workspace

Full-size fridge, microwave, stovetop, dishwasher

Residence Inn Durham McPherson/Duke University Medical Center offers a refreshed retreat with practical comforts. Enjoy a to-go breakfast, relax by the lobby fireplace, and request complimentary grocery shopping. WiFi in all rooms and an area shuttle make attractions accessible.

Wonderful

Popular amenities

Bar
Kitchen
Parking available
Pet friendly

Room options

Check availability for these dates

Tonight

Oct 26 - Oct 27

Tomorrow

Oct 27 - Oct 28

All rooms

1 bed

2 beds

3+ beds

Showing 10 of 10 rooms

32-inch Smart TV with cable channels, TV, Netflix

Suite, 1 Bedroom

Wonderful

Highlights

Separate sitting area

Air conditioning

Kitchen

Full-sized refrigerator/freezer

Dining table

Dishwasher

Smart TV

Renovated in 2024

469 sq ft
1 bedroom
Sleeps 3
1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed

1 bedroom, in-room safe, desk, laptop workspace

Studio, 1 King Bed with Sofa bed, Non Smoking

Excellent

Highlights

Separate sitting area

Air conditioning

Kitchen

Full-sized refrigerator/freezer

Dining table

Dishwasher

Smart TV

Renovated in 2024

480 sq ft
Sleeps 3
1 King Bed and 1 Double Sofa Bed

Studio, 1 Queen Bed with Sofa bed, Non Smoking

Exceptional

Highlights

Separate sitting area

Air conditioning

Kitchen

Full-sized refrigerator/freezer

Dining table

Dishwasher

Smart TV

Renovated in 2024

424 sq ft
Sleeps 3
1 Queen Bed and 1 Double Sofa Bed

Suite, 1 Bedroom, Non Smoking (Hearing Accessible)

Excellent

Highlights

Separate sitting area

Air conditioning

Kitchen

Full-sized refrigerator/freezer

Dining table

Dishwasher

Smart TV

Renovated in 2024

Sleeps 3
1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed

Studio, 1 King Bed with Sofa bed (Mobility/Hearing Accessible, Tub)

Highlights

Separate sitting area

Air conditioning

Kitchen

Full-sized refrigerator/freezer

Dining table

Dishwasher

Smart TV

Renovated in 2024

478 sq ft
Sleeps 3
1 King Bed and 1 Double Sofa Bed

Studio, 1 King Bed with Sofa bed (Mobility Accessible, Tub)

Highlights

Separate sitting area

Air conditioning

Kitchen

Full-sized refrigerator/freezer

Dining table

Dishwasher

Smart TV

Renovated in 2024

479 sq ft
Sleeps 3
1 King Bed and 1 Double Sofa Bed

Studio, 1 King Bed with Sofa bed (Hearing Accessible)

Highlights

Separate sitting area

Air conditioning

Kitchen

Full-sized refrigerator/freezer

Dining table

Dishwasher

Smart TV

Renovated in 2024

479 sq ft
Sleeps 3
1 King Bed and 1 Double Sofa Bed

Studio, 1 Queen Bed with Sofa bed (Hearing Accessible)

Highlights

Separate sitting area

Air conditioning

Kitchen

Full-sized refrigerator/freezer

Dining table

Dishwasher

Smart TV

Renovated in 2024

426 sq ft
Sleeps 3
1 Queen Bed and 1 Double Sofa Bed

Suite, Multiple Beds, Non Smoking (Mobility Accessible, Tub)

Highlights

Separate sitting area

Air conditioning

Kitchen

Full-sized refrigerator/freezer

Dining table

Dishwasher

Smart TV

Renovated in 2024

Sleeps 5
2 Queen Beds and 1 Double Sofa Bed

Suite, 1 Bedroom, Non Smoking (Mobility Accessible, Roll-in Shower)

Exceptional

Highlights

Separate sitting area

Air conditioning

Kitchen

Full-sized refrigerator/freezer

Dining table

Dishwasher

Smart TV

Renovated in 2024

Sleeps 3
1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed

About the neighborhood

Located in Downtown Durham, a neighborhood in Durham, Residence Inn Durham McPherson/Duke University Medical Cntr is near a train station. Pauli Murray Center for History and Social Justice and American Tobacco Campus are local landmarks, and some of the area's attractions include Sarah P. Duke Gardens and Museum of Life and Science. Looking to enjoy an event or a game while in town? See what's going on at Durham Bulls Athletic Park, or consider a night out at Dean Smith Center.

Visit our Durham travel guide

1108 West Main Street, Durham, NC, 27701

What's nearby

Duke University - 3 min walk - 0.2 miles
Durham Bulls Athletic Park - 16 min walk - 0.9 miles
Durham Performing Arts Center - 17 min walk - 0.9 miles
Duke University Hospital - 2 min drive - 1.7 miles
Cameron Indoor Stadium - 6 min drive - 2.5 miles

Getting around

Durham Station - 8 min walk
Raleigh-Durham International Airport (RDU) - 19 min drive

Restaurants

‪The Can Opener - ‬7 min walk
‪Ramblers - ‬7 min walk
‪Fonda Lupita - ‬3 min walk
‪Emmy Squared - ‬5 min walk
‪Clouds Brewcade + Kitchen - ‬4 min walk

About this property

Residence Inn Durham McPherson/Duke University Medical Cntr

Hotel remodeled in 2024 and located near Duke University

Consider a stay at Residence Inn Durham McPherson/Duke University Medical Cntr and take advantage of free to-go breakfast, a free grocery shopping service, and a terrace. In addition to dry cleaning/laundry services and a fireplace in the lobby, guests can connect to free in-room WiFi.

Other perks include:

A free area shuttle, self parking (surcharge), and express check-out
Express check-in, wedding services, and an elevator
Laundry services, luggage storage, and smoke-free premises
Guest reviews speak highly of the helpful staff

Room features

All 147 rooms include comforts such as laptop-friendly workspaces and air conditioning, in addition to thoughtful touches like free WiFi and desk chairs.

Extra conveniences in all rooms include:

Recycling and LED light bulbs
Shower/tub combinations, free toiletries, and hair dryers
32-inch Smart TVs with Netflix and premium channels
Wardrobes/closets, separate sitting areas, and kitchens

Similar properties

Pet friendly
Free WiFi
Restaurant
Air conditioning

$127 nightly

Nov 23 - Nov 24

Total with taxes and fees

Property amenities

Internet

Available in all rooms: Free WiFi
Available in some public areas: Free WiFi

Parking and transportation

Free area shuttle
Self parking on site (USD 15 per day)
Wheelchair-accessible parking available

Food and drink

Free on-the-go breakfast available daily 7:00 AM to 9:00 AM
A bar/lounge
Coffee and tea in common areas

Things to do

24-hour gym

Family friendly

Dining table
Free area shuttle
Grocery/convenience store
In-room full-sized refrigerator/freezer
In-room kitchen
In-room microwave
Laundry facilities

Conveniences

24-hour front desk
Free newspapers in lobby
Grocery/convenience store
Laundry facilities
Luggage storage
Safe at front desk

Guest services

Change of bedsheets (on request)
Change of towels on request
Concierge services
Dry cleaning/laundry service
Free grocery shopping service
Housekeeping (daily)
Wedding services

Business services

2,530 square feet of conference space
Business center
Computer station

Outdoors

Terrace

Accessibility

If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
7 accessible parking spaces
Assistive listening devices in meeting rooms
Braille/raised signage
Elevator (42 inch wide door)
Hardwood flooring in room
Lever door handles
Thin carpet in room
Visual alarms in hallways
Wheelchair accessible (may have limitations)
Wheelchair-accessible business center
Wheelchair-accessible gym
Wheelchair-accessible lounge
Wheelchair-accessible parking
Wheelchair-accessible path of travel
Wheelchair-accessible path to elevator
Wheelchair-accessible registration desk (34 inches high)
Wheelchair-accessible restaurant

More

5 floors
Banquet hall
Biodegradable coffee stirrers available
Built in 2015
Comprehensive recycling policy
Double-glazed windows
Fireplace in lobby
No plastic coffee stirrers
No plastic drinking straws
Renovated entire property - April 2024
Smoking not allowed
Vegan dining options
Vegetarian breakfast available
Vegetarian dining options

Room amenities

Bedroom

Bedsheets provided
Blackout drapes

Bathroom

Free toiletries
Hair dryer
Shower/bathtub combination
Towels provided

Entertainment

32-inch smart TV with premium cable channels
Netflix
Pay movies

Food and drink

Coffee/tea maker
Cookware, dishware, and utensils
Dining table
Dishwasher
Full-sized refrigerator/freezer
Kitchen
Microwave
Stovetop

More

Air conditioning (climate-controlled)
Desk
Desk chair
Energy-saving switches in guestrooms
Free local calls
Iron/ironing board
Laptop workspace
LED lighting
Phone
Recycling
Safe
Separate sitting area
Water-efficient showers

Policies

Check-in

Check-in start time: 3 PM; Check-in end time: midnight

Express check-in available

Minimum check-in age: 21

Check-out

Check-out before noon

Contactless check-out available

Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

Pets allowed for an extra charge of USD 100.00 per pet (varies based on length of stay)

Service animals are welcome, and are exempt from fees

2 total (up to 100 lbs per pet)

Restrictions apply; for more information contact the property at the number on the booking confirmation

Children and extra beds

Children are welcome

Rollaway/extra beds are not available

Cribs (infant beds) are not available

Property payment types

Important information

Optional extras

Self parking fee: USD 15 per day
Pet fee: USD 100.00 per pet (varies based on length of stay)
Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy

Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges

Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed

This property accepts credit cards; cash is not accepted

Safety features at this property include a carbon monoxide detector and a smoke detector

This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Marriott)

We should mention

Guests under 18 years old are not allowed in the fitness facility, and guests under 18 years old are only allowed in the swimming pool and fitness facility with adult supervision

This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

Residence Inn McPherson/Duke University Medical Cntr Hotel

Residence Inn Durham McPherson/Duke University Medical Cntr

Residence Inn McPherson/Duke University Medical Cntr

Residence Inn McPherson/Duke University Medical Cntr Hotel

Residence Inn McPherson/Duke University Medical Cntr

Frequently asked questions

Is Residence Inn Durham McPherson/Duke University Medical Cntr pet-friendly?

Yes, Residence Inn Durham McPherson/Duke University Medical Cntr allows pets (limit 2 total) with a maximum weight of up to 100 lbs per pet. There's a fee of USD 100.00 per pet, per stay. Service animals are exempt from fees. Some restrictions may apply, so please contact the property for more details.

How much does it cost to stay at Residence Inn Durham McPherson/Duke University Medical Cntr?

As of Oct 26, 2025, prices found for a 1-night stay for 2 adults at Residence Inn Durham McPherson/Duke University Medical Cntr on Nov 1, 2025 start from $157.52, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

How much is parking at Residence Inn Durham McPherson/Duke University Medical Cntr?

Self parking is available for USD 15 per day.

What time is check-in at Residence Inn Durham McPherson/Duke University Medical Cntr?

Check-in start time: 3 PM; Check-in end time: midnight.

What time is check-out at Residence Inn Durham McPherson/Duke University Medical Cntr?

Check-out is at noon.

Where is Residence Inn Durham McPherson/Duke University Medical Cntr located?

Located in Downtown Durham, this hotel is within a 10-minute walk of Brightleaf Square and Duke University. Carolina Theatre and Durham Convention Center are also within 15 minutes. Durham Station is 8 minutes by foot.

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Residence Inn Durham McPherson/Duke University Medical Cntr Reviews

9.2

Wonderful

9.4

Cleanliness

9.0

Location

9.4

Staff & service

9.0

Eco-friendliness

9.4

Property conditions & facilities

8/10 Good

James

Oct 13, 2025

Liked: Cleanliness, staff & service, amenities, property conditions & facilities

Nice hotel for the price. Good location. Big rooms. Quiet. Easy parking. Could be a little cleaner.

Stayed 2 nights in Oct 2025

10/10 Excellent

Derek

Aug 5, 2025

Liked: Cleanliness, staff & service, property conditions & facilities

Was very nice. The staff was very polite when we arrived.

Stayed 1 night in Aug 2025

10/10 Excellent

Anthony

Sep 27, 2025

Liked: Amenities

Yes

Stayed 4 nights in Sep 2025

8/10 Good

Maria

Aug 19, 2025

Liked: Cleanliness, staff & service, amenities

Great location! You can walk to great restaurants and coffee shops. The room is clean and spacious. The bed is very comfortable and it felt like a nice treat at the end of long day. The staff is very friendly, specially Tiffani and Laura at the reception desk. They were very helpful and welcoming, always greeting you with a big smile and making sure we were doing fine. I will definitely stay there on my next visit.

Stayed 7 nights in Aug 2025

8/10 Good

Heman

Jul 18, 2025

Liked: Cleanliness, amenities, property conditions & facilities

Laura and Tiffany were extremely helpful and accommodating. The whole staff was very friendly and welcoming!

Stayed 9 nights in Jul 2025

10/10 Excellent

LaMeesha

Jun 26, 2025

Liked: Cleanliness, staff & service, amenities, property conditions & facilities

I am thankful for the very hospitable staff that I encountered at the hotel. Everyone was smiling at the front desk every time I passed by.

Stayed 8 nights in Jun 2025

10/10 Excellent

Melissa

Jul 29, 2025

Liked: Cleanliness, staff & service, amenities, property conditions & facilities

Staff was amazing! Breakfast had so many options, quiche, waffles, fresh fruit, sausage, hard boiled eggs…. Room was very clean. Small market store in lobby. Lobby area with a tv and tons of seating. Nice workout room. But again, staff was incredible!

Stayed 8 nights in Jul 2025

10/10 Excellent

Timmy

Jun 9, 2025

Liked: Cleanliness, amenities, property conditions & facilities

It was very clean and the staff was excellent. The stay was really good. The attendant was great at checking.

Stayed 1 night in Jun 2025

8/10 Good

Minor

Feb 2, 2025

Liked: Cleanliness, staff & service

An excellent place to stay!

Stayed 1 night in Feb 2025

10/10 Excellent

Kaiqing

Jul 19, 2025

Liked: Cleanliness, staff & service, property conditions & facilities

All good as expected

Stayed 14 nights in Jul 2025

10/10 Excellent

Ronnie A.

Jul 26, 2025

Liked: Cleanliness, staff & service, property conditions & facilities

We had an issue with the room but the district manager took care of it immediately. Excellent Team

Stayed 8 nights in Jul 2025

10/10 Excellent

David

May 31, 2025

Liked: Cleanliness, staff & service, amenities, property conditions & facilities

We love staying here when we come to visit our family. Every stay has been wonderful. The room is very comfortable. We love the gym and the breakfasts. Having a nice laundry area on the premises is also a huge plus. The best part is the fantastic staff-everyone is so nice and helpful. Thank you for always making our trips memorable.

Stayed 7 nights in May 2025

10/10 Excellent

Reed

May 10, 2025

Liked: Cleanliness, staff & service, amenities, property conditions & facilities

The place to stay if you have business at Duke. Housekeeping is hit-or-miss, but that's par for the course for an extended-stay hotel.

Stayed 6 nights in Apr 2025

8/10 Good

PRAVEEN

Jul 7, 2025

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Good place to stay ...convenient to walk to Duke

The check in was super nice. The air conditioner was making a lot of noise - a racket. We had to complain multiple times. But they did respond 🙄 after the third vociferous complaint and replaced compressor. Friendly maintainence team , Barry the maintainence executive brought in a lot of smiles with his attitude.

Stayed 14 nights in Jun 2025

8/10 Good

Robert

May 21, 2025

Liked: Cleanliness, staff & service, amenities, property conditions & facilities

Shoutout to Tiffany/Stephanie? on front desk duty - she greeted us with a warm welcome & useful information!

Stayed 1 night in May 2025

8/10 Good

Lourdes Dolores

Jul 8, 2025

Liked: Cleanliness, property conditions & facilities, room comfort

Wasteful shower design

The room was clean and comfortable and the gym was good. However, I gave the hotel 3 stars because the shower lets out so much water that it is actually wasting water. There's no door for the shower, so when you bathe, the water streams out of the shower and onto the bathroom floor. So much water streams out that I had to place the bathmat 12 inches away from the shower entrance so that it wouldn't get wet.

Stayed 10 nights in Jun 2025

10/10 Excellent

Margaret

Sep 27, 2024

Liked: Cleanliness, staff & service, amenities, property conditions & facilities

Great and reasonably priced place to stay as a family in the center of Durham.

Stayed 1 night in Sep 2024

10/10 Excellent

Wendy

Sep 19, 2024

Liked: Cleanliness, staff & service, amenities, property conditions & facilities

Clean, friendly, great location.

Stayed 1 night in Sep 2024

6/10 Okay

Tian

May 30, 2025

Disliked: Staff & service, amenities

It smelled musky and like urine in our room and much of the facility just smelled like cleaning supplies. The wifi wasn’t great in the room. The location is decently close to Duke, but the immediate area is at a street intersection right by a gas station. There was plenty of parking for pay by mobile 15$.

Stayed 1 night in May 2025

10/10 Excellent

Jo Anne

May 7, 2024

Liked: Cleanliness, staff & service, property conditions & facilities

Great place

Stayed 2 nights in May 2024

10/10 Excellent

Christopher

Jan 30, 2024

Liked: Cleanliness, staff & service, amenities, property conditions & facilities

Great place!

Stayed 3 nights in Dec 2023

10/10 Excellent

eric

Oct 28, 2024

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

The place to stay!!

A very clean and quiet hotel property with great breakfast in the morning. Ample parking and reasonably priced. All of the staff were very friendly. Would definitely recommend.

Stayed 2 nights in Oct 2024