Residence Inn Durham McPherson/Duke University Medical Cntr

3.0 star property
Hotel with free breakfast, a short walk to Duke University

Choose dates to view prices

Photo gallery for Residence Inn Durham McPherson/Duke University Medical Cntr

Courtyard
Exterior
Lobby
Suite, Multiple Beds, Non Smoking (Mobility Accessible, Tub) | 1 bedroom, in-room safe, desk, laptop workspace
Full-size fridge, microwave, stovetop, dishwasher
Residence Inn Durham McPherson/Duke University Medical Center offers a refreshed retreat with practical comforts. Enjoy a to-go breakfast, relax by the lobby fireplace, and request complimentary grocery shopping. WiFi in all rooms and an area shuttle make attractions accessible.

Reviews

9.2 out of 10
Wonderful

Popular amenities

  • Bar
  • Kitchen
  • Parking available
  • Pet friendly
  • Housekeeping

Room options

Available filters for rooms
Showing 10 of 10 rooms

Suite, 1 Bedroom

9.2 out of 10
Wonderful
(5 reviews)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized refrigerator/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
  • 469 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed

Studio, 1 King Bed with Sofa bed (Mobility/Hearing Accessible, Tub)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized refrigerator/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
  • 478 sq ft
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

Studio, 1 King Bed with Sofa bed, Non Smoking

8.8 out of 10
Excellent
(31 reviews)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized refrigerator/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
  • 480 sq ft
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

Studio, 1 King Bed with Sofa bed (Mobility Accessible, Tub)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized refrigerator/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
  • 479 sq ft
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

Suite, 1 Bedroom, Non Smoking (Hearing Accessible)

10.0 out of 10
Exceptional
(2 reviews)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized refrigerator/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed

Suite, Multiple Beds, Non Smoking (Mobility Accessible, Tub)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized refrigerator/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
  • Sleeps 5
  • 2 Queen Beds and 1 Double Sofa Bed

Suite, 1 Bedroom, Non Smoking (Mobility Accessible, Roll-in Shower)

10.0 out of 10
Exceptional
(1 review)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized refrigerator/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed

Studio, 1 King Bed with Sofa bed (Hearing Accessible)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized refrigerator/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
  • 479 sq ft
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

Studio, 1 Queen Bed with Sofa bed, Non Smoking

9.6 out of 10
Exceptional
(14 reviews)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized refrigerator/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
  • 424 sq ft
  • Sleeps 3
  • 1 Queen Bed and 1 Double Sofa Bed

Studio, 1 Queen Bed with Sofa bed (Hearing Accessible)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized refrigerator/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
  • 426 sq ft
  • Sleeps 3
  • 1 Queen Bed and 1 Double Sofa Bed

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About the neighborhood

Located in Downtown Durham, a neighborhood in Durham, Residence Inn Durham McPherson/Duke University Medical Cntr is near a train station. Sarah P. Duke Gardens and Museum of Life and Science are local attractions and those in the mood for shopping can visit Brightleaf Square and Northgate Mall. Looking to enjoy an event or a game while in town? See what's happening at Pauli Murray Center for History and Social Justice or Durham Bulls Athletic Park.
Map
1108 West Main Street, Durham, NC, 27701

What's nearby

  • Duke University - 3 min walk - 0.2 miles
  • Durham Bulls Athletic Park - 16 min walk - 0.9 miles
  • Durham Performing Arts Center - 17 min walk - 0.9 miles
  • Duke University Hospital - 2 min drive - 1.7 miles
  • Cameron Indoor Stadium - 6 min drive - 2.5 miles

Getting around

  • Durham Station - 8 min walk
  • Raleigh-Durham International Airport (RDU) - 19 min drive

Restaurants

  • ‪Atomic Clock Brewing Co - ‬11 min walk
  • ‪The Can Opener - ‬7 min walk
  • ‪Fonda Lupita - ‬3 min walk
  • ‪Ramblers - ‬7 min walk
  • ‪Emmy Squared - ‬5 min walk

About this property

Residence Inn Durham McPherson/Duke University Medical Cntr

Hotel remodeled in 2024 and located near Duke University
Consider a stay at Residence Inn Durham McPherson/Duke University Medical Cntr and take advantage of free to-go breakfast, a free grocery shopping service, and a terrace. In addition to dry cleaning/laundry services and a fireplace in the lobby, guests can connect to free in-room WiFi.
Other perks include:
  • A free area shuttle, self parking (surcharge), and express check-out
  • Express check-in, a banquet hall, and concierge services
  • Luggage storage, a computer station, and a 24-hour front desk
  • Guest reviews speak highly of the helpful staff
Room features
All 147 rooms include comforts such as laptop-friendly workspaces and air conditioning, in addition to thoughtful touches like free WiFi and desk chairs.
Extra conveniences in all rooms include:
  • Recycling and LED light bulbs
  • Shower/tub combinations, free toiletries, and hair dryers
  • 32-inch Smart TVs with Netflix and premium channels
  • Wardrobes/closets, separate sitting areas, and kitchens

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Free area shuttle
  • Self parking on site (USD 15 per day)
  • Wheelchair-accessible parking available

Food and drink

  • Free on-the-go breakfast available daily 7:00 AM to 9:00 AM
  • A bar/lounge
  • Coffee and tea in common areas

Things to do

  • 24-hour gym

Family friendly

  • Dining table
  • Free area shuttle
  • Grocery/convenience store
  • In-room full-sized refrigerator/freezer
  • In-room kitchen
  • In-room microwave
  • Laundry facilities

Conveniences

  • 24-hour front desk
  • Free newspapers in lobby
  • Grocery/convenience store
  • Laundry facilities
  • Luggage storage
  • Safe at front desk

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Concierge services
  • Dry cleaning/laundry service
  • Free grocery shopping service
  • Housekeeping (daily)
  • Wedding services

Business services

  • 2,530 square feet of conference space
  • Business center
  • Computer station

Outdoors

  • Terrace

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • 7 accessible parking spaces
  • Assistive listening devices in meeting rooms
  • Braille/raised signage
  • Elevator (42 inch wide door)
  • Hardwood flooring in room
  • Lever door handles
  • Thin carpet in room
  • Visual alarms in hallways
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible business center
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible registration desk (34 inches high)
  • Wheelchair-accessible restaurant

More

  • 5 floors
  • Banquet hall
  • Biodegradable coffee stirrers available
  • Built in 2015
  • Comprehensive recycling policy
  • Double-glazed windows
  • Fireplace in lobby
  • No plastic coffee stirrers
  • No plastic drinking straws
  • Renovated entire property - April 2024
  • Smoking not allowed
  • Vegan dining options
  • Vegetarian breakfast available
  • Vegetarian dining options

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Free toiletries
  • Hair dryer
  • Shower/bathtub combination
  • Towels provided

Entertainment

  • 32-inch smart TV with premium cable channels
  • Netflix
  • Pay movies

Food and drink

  • Coffee/tea maker
  • Cookware, dishware, and utensils
  • Dining table
  • Dishwasher
  • Full-sized refrigerator/freezer
  • Kitchen
  • Microwave
  • Stovetop

More

  • Air conditioning (climate-controlled)
  • Desk
  • Desk chair
  • Energy-saving switches in guestrooms
  • Free local calls
  • Iron/ironing board
  • Laptop workspace
  • LED lighting
  • Phone
  • Recycling
  • Safe
  • Separate sitting area
  • Water-efficient showers

Policies

Check-in

Check-in start time: 3 PM; Check-in end time: midnight
Express check-in available
Minimum check-in age: 21

Check-out

Check-out before noon
Contactless check-out available
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

Pets allowed for an extra charge of USD 100.00 per pet (varies based on length of stay)
Service animals are welcome, and are exempt from fees
2 total (up to 100 lbs per pet)
Restrictions apply; for more information contact the property at the number on the booking confirmation

Children and extra beds

Children are welcome
Rollaway/extra beds are not available
Cribs (infant beds) are not available

Property payment types

Important information

Optional extras

  • Self parking fee: USD 15 per day
  • Pet fee: USD 100.00 per pet (varies based on length of stay)
  • Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a carbon monoxide detector and a smoke detector
This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Marriott)

We should mention

Guests under 18 years old are not allowed in the fitness facility, and guests under 18 years old are only allowed in the swimming pool and fitness facility with adult supervision
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

Residence Inn McPherson/Duke University Medical Cntr Hotel
Residence Inn Durham McPherson/Duke University Medical Cntr
Residence Inn McPherson/Duke University Medical Cntr
Residence Inn McPherson/Duke University Medical Cntr Hotel
Residence Inn McPherson/Duke University Medical Cntr Hotel
Residence Inn McPherson/Duke University Medical Cntr

Frequently asked questions

Is Residence Inn Durham McPherson/Duke University Medical Cntr pet-friendly?

Yes, Residence Inn Durham McPherson/Duke University Medical Cntr allows pets (limit 2 total) with a maximum weight of up to 100 lbs per pet. There's a fee of USD 100.00 per pet, per stay. Service animals are exempt from fees. Some restrictions may apply, so please contact the property for more details.

How much does it cost to stay at Residence Inn Durham McPherson/Duke University Medical Cntr?

As of Sep 10, 2025, prices found for a 1-night stay for 2 adults at Residence Inn Durham McPherson/Duke University Medical Cntr on Sep 29, 2025 start from $192.72, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

How much is parking at Residence Inn Durham McPherson/Duke University Medical Cntr?

Self parking is available for USD 15 per day.

What time is check-in at Residence Inn Durham McPherson/Duke University Medical Cntr?

Check-in start time: 3 PM; Check-in end time: midnight.

What time is check-out at Residence Inn Durham McPherson/Duke University Medical Cntr?

Check-out is at noon.

Where is Residence Inn Durham McPherson/Duke University Medical Cntr located?

Located in Downtown Durham, this hotel is within a 10-minute walk of Brightleaf Square and Duke University. Carolina Theatre and Durham Convention Center are also within 15 minutes. Durham Station is 8 minutes by foot.

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