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Compare 261 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Hampton Inn Cape Girardeau I 55 East
Courtyard

Hampton Inn Cape Girardeau I 55 East

2.5 star property
9.6 out of 10, Exceptional, (721)
"Great place to stay convenient walking to multiple restaurants"
$110 nightly
The price is $124
Jul 13 - Jul 14
Total includes taxes and fees
Hampton Inn Cape Girardeau I 55 East
Drury Inn & Suites Jackson MO
Lobby

Drury Inn & Suites Jackson MO

3.0 star property
9.6 out of 10, Exceptional, (1004)
"Great staff "
$90 nightly
The price is $95
Jul 13 - Jul 14
Total includes taxes and fees
Drury Inn & Suites Jackson MO
The Riverview
Grand Riverview Two Queen Room | 1 bedroom, premium bedding, pillowtop beds, in-room safe

The Riverview

2.0 star property
9.4 out of 10, Exceptional, (318)
"Everyone is very helpful, great rooms, we will stay there again."
$117 nightly
The price is $132
Jul 7 - Jul 8
Total includes taxes and fees
The Riverview
Drury Inn & Suites Sikeston, MO
Property amenity

Drury Inn & Suites Sikeston, MO

3.0 star property
9.4 out of 10, Exceptional, (1003)
"Always the best hotel in any town. "
$102 nightly
The price is $117
Jul 10 - Jul 11
Total includes taxes and fees
Drury Inn & Suites Sikeston, MO
Pear Tree Inn Cape Girardeau West
Lobby

Pear Tree Inn Cape Girardeau West

2.5 star property
9.0 out of 10, Wonderful, (1003)
"Front desk staff was very friendly and helpful."
$73 nightly
The price is $82
Jul 13 - Jul 14
Total includes taxes and fees
Pear Tree Inn Cape Girardeau West
Drury Inn & Suites Cape Girardeau
Business center

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (953)
"Room was very clean and staff was excellent!"
$90 nightly
The price is $102
Jul 13 - Jul 14
Total includes taxes and fees
Drury Inn & Suites Cape Girardeau
Courtyard by Marriott Cape Girardeau Downtown
Lobby lounge

Courtyard by Marriott Cape Girardeau Downtown

3.0 star property
9.6 out of 10, Exceptional, (425)
"Unique place in a historic local building - the bank vault was cool!"
$122 nightly
The price is $139
Jul 27 - Jul 28
Total includes taxes and fees
Courtyard by Marriott Cape Girardeau Downtown
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Property amenity

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property
8.8 out of 10, Excellent, (578)
"I liked that it was quiet and breakfast was good."
$86 nightly
The price is $93
Jul 9 - Jul 10
Total includes taxes and fees
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Drury Plaza Hotel Cape Girardeau Conference Center
Lobby

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
9.6 out of 10, Exceptional, (1007)
"The staff was very friendly and the hotel was very clean!"
$90 nightly
The price is $102
Jul 13 - Jul 14
Total includes taxes and fees
Drury Plaza Hotel Cape Girardeau Conference Center
Pear Tree Inn Cape Girardeau Near the Medical Center
Property entrance

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1003)
"Excellent place to stay "
$67 nightly
The price is $76
Jul 10 - Jul 11
Total includes taxes and fees
Pear Tree Inn Cape Girardeau Near the Medical Center
Hampton Inn Sikeston
Exterior

Hampton Inn Sikeston

2.5 star property
8.8 out of 10, Excellent, (360)
"Clean, great breakfast, quiet, friendly staff"
$118 nightly
The price is $134
Jul 13 - Jul 14
Total includes taxes and fees
Hampton Inn Sikeston
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Exterior

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1002)
"Great place to stay. "
$105 nightly
The price is $118
Aug 1 - Aug 2
Total includes taxes and fees
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Fairfield Inn & Suites by Marriott Cape Girardeau
Lobby lounge

Fairfield Inn & Suites by Marriott Cape Girardeau

2.5 star property
9.4 out of 10, Exceptional, (113)
"Hotel was very clean and the lady that checked us in was very friendly. "
$93 nightly
The price is $105
Jul 13 - Jul 14
Total includes taxes and fees
Fairfield Inn & Suites by Marriott Cape Girardeau
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Hallway

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

2.5 star property
8.4 out of 10, Very Good, (659)
"Property is always clean, rooms are nice."
$65 nightly
The price is $75
Jul 8 - Jul 9
Total includes taxes and fees
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Pear Tree Inn Sikeston
Lobby

Pear Tree Inn Sikeston

2.5 star property
9.4 out of 10, Exceptional, (1003)
"Great place to stay with kids "
$90 nightly
The price is $103
Jul 10 - Jul 11
Total includes taxes and fees
Pear Tree Inn Sikeston
Tru By Hilton Cape Girardeau
Room, 2 Queen Beds

Tru By Hilton Cape Girardeau

2.5 star property
9.6 out of 10, Exceptional, (36)
"It was a quick stay for work but the place was very nice and clean! I like the way they do breakfast too. "
$101 nightly
The price is $115
Jul 13 - Jul 14
Total includes taxes and fees
Tru By Hilton Cape Girardeau
Rockwood Inn
Standard Room, 1 Queen Bed, Non Smoking, Garden View | 1 bedroom, free WiFi

Rockwood Inn

2.0 star property
10.0 out of 10, Exceptional, (12)
"The property was historic and renovations were perfect. Each room hads a bathroom, the beds were great. It was lovely and peaceful. "
$150 nightly
The price is $170
Jul 13 - Jul 14
Total includes taxes and fees
Rockwood Inn
Comfort Inn & Suites Sikeston I-55
Exterior

Comfort Inn & Suites Sikeston I-55

2.5 star property
8.4 out of 10, Very Good, (266)
"The facility was very nice. "
$89 nightly
The price is $102
Jul 13 - Jul 14
Total includes taxes and fees
Comfort Inn & Suites Sikeston I-55
Best Western Plus Sikeston
Lobby

Best Western Plus Sikeston

2.5 star property
8.4 out of 10, Very Good, (1005)
"We enjoyed our stay and the breakfast was good!"
$89 nightly
The price is $101
Jul 13 - Jul 14
Total includes taxes and fees
Best Western Plus Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Sikeston, MO

Showing deals for:Jul 18 - Jul 20

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Room

Rockwood Inn

2.0 star property
Cape Girardeau
10/10Exceptional (12 reviews)
10% off
$180 nightly
Price is $407
Total with taxes and fees
Rockwood Inn
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Sikeston and related destinations

Home to Lambert's Café, the 'Home of Throwed Rolls,' where servers toss fresh bread across the room to hungry diners. Visit the historic Sikeston Depot or catch the annual rodeo where professional cowboys compete in thrilling events each August.

See all hotels in Sikeston
The best restaurant I have EVER been to! Hands down!!!
Photo by Ryan Coleman
Open Photo by Ryan Coleman

Find out more about Sikeston

Find out more about Sikeston

Top reasons to visit Sikeston

  • Outdoor Adventures: Sikeston offers a variety of recreational areas perfect for outdoor enthusiasts, including parks and scenic views.
  • Casino Fun: Try your luck at the local casino for an exciting night out.
  • Cultural Experiences: Visit art museums and event venues to immerse yourself in the local culture.
  • Charming Atmosphere: Enjoy the warm, welcoming vibe of this friendly farm town.
  • Affordable Accommodations: Find a range of comfortable and budget-friendly hotels to enhance your stay.

Find great hotels in Sikeston

Explore a variety of hotel accommodations in Sikeston, Missouri, where comfort meets affordability. Whether you're looking for pet-friendly options or business-themed stays, the city offers a selection of 2 to 3-star hotels to suit your needs. From cozy suites to welcoming environments for LGBTQIA travelers, find the ideal lodging for your vacation experience in Sikeston, including popular choices like Wyndham Sikeston among others.

  • Pear Tree Inn Sikeston: Ideal for families and business travelers alike, Pear Tree Inn Sikeston offers a welcoming atmosphere that is both pet-friendly and functional. This hotel is designed with families in mind, featuring amenities such as cribs at no extra charge. Business guests will appreciate the dedicated business center, while pets are also accommodated with specific policies in place. The property strikes a balance between comfort and convenience, making it a great choice for those traveling with children or furry companions.
  • Days Inn and Suites by Wyndham Sikeston: Known for its business-friendly environment, Days Inn and Suites by Wyndham Sikeston caters to working travelers while providing a pet-friendly experience. This hotel features multiple meeting rooms, making it easy to host small gatherings or meetings. Guests with pets will find a welcoming atmosphere that respects their needs, with clear policies in place. Whether you are in town for work or leisure, this hotel combines functionality with comfort for a seamless stay.
  • Best Western Plus Sikeston: Best Western Plus Sikeston is an excellent choice for pet owners seeking comfort and convenience. This hotel ensures that your furry friends are welcome while maintaining a focus on guest satisfaction. With clear pet policies and accommodating amenities, guests can relax knowing their pets are well cared for. The hotel’s inviting atmosphere and commitment to service make it a top pick for travelers looking for a pleasant stay in Sikeston.

Where to stay in and around Sikeston

Sikeston, Missouri, offers a delightful blend of outdoor adventures and charming scenery, perfect for a romantic getaway or family-friendly vacation. Explore the warm, welcoming atmosphere of this farm town and enjoy excursions that showcase the friendly spirit of its residents. Nearby attractions promise leisure and budget-friendly experiences, making Sikeston an ideal destination for travelers seeking a memorable trip in the heart of the United States.

  • Miner: Nestled within the Sikeston area, Miner is a charming village that offers a delightful blend of outdoor activities and family-friendly experiences. The vibrant community invites travelers year-round, with peak visits in January and during the summer months of June to July. Visitors can enjoy scenic views while exploring local parks and recreational areas. Shopping enthusiasts will appreciate the nearby mall centers, while nature lovers can visit landmarks such as a beautiful lake and a national state park, making Miner a perfect spot for a relaxing getaway.
  • Morehouse: Located a mere 6 miles from Sikeston, Morehouse is a quaint city that boasts a welcoming atmosphere for tourists. With visitor numbers peaking from June to August, this city offers a variety of seasonal experiences that capture the essence of small-town charm. While in Morehouse, take a leisurely stroll through its parks or engage with the friendly locals to discover hidden gems and local favorites, making your visit both enriching and enjoyable.
  • Bertrand: Just 8 miles from Sikeston, Bertrand is a vibrant city known for its outdoor adventure opportunities and family-friendly atmosphere. The city attracts visitors most in January, April, and August, providing ample chances for exploration throughout the year. Nature enthusiasts will love the nearby visitor center and nature reserve, as well as the serene lake that offers various recreational activities. Bertrand's welcoming vibe and beautiful landscapes make it an ideal destination for those seeking adventure and quality time with loved ones.

Things to do in and around Sikeston

Sikeston, Missouri, is an ideal destination for outdoor enthusiasts and couples seeking a romantic getaway. Visitors can enjoy a variety of activities, including exploring its recreational areas, trying their luck at the local casino, and attending events at the arena entertainment facility. With its charming atmosphere and numerous attractions, Sikeston promises a memorable experience for all who visit.

Shopping

For a unique shopping experience, check out The Book Bug in Sikeston, which offers a delightful selection of books and gifts. If you're up for a drive, you can explore additional malls and markets nearby for even more shopping options.

Recreation

Boot Heel Golf Club offers a scenic golfing experience with outdoor sports vibes, perfect for enjoying a day on the greens. For relaxation, visit eDen Spa & Salon, located 29 miles away, where you can indulge in rejuvenating body treatments that promote wellness and tranquility.

Nightlife

If you're feeling lucky, take a short drive to Isle Casino Cape Girardeau, about 30 miles from Sikeston, for a night of gaming and excitement. Enjoy the vibrant city atmosphere, indulge in fine dining, and soak up the romantic ambiance at this popular local destination.

Booking tips and Expedia advantages for Sikeston

To save money on your trip to Sikeston, visit during the cheaper months of November to January, and aim for a Tuesday stay to avoid the higher Saturday rates. Utilize affordable transportation options like walking or biking to explore the area. For lodging, consider booking through Expedia, where you can filter prices to find the best deals and even save more by bundling your hotel stay with flights. Joining Expedia's One Key membership can also unlock exclusive discounts and rewards for future stays.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Sikeston are November to January, where the prices are slightly lower. This is in comparison to April to June, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Sikeston is Tuesday. The most expensive day to stay in Sikeston is Saturday.
  • Find cheap hotels on Expedia: Explore your travel options with Expedia’s search tool, where you can easily customize your search based on your budget, desired location, and the type of hotel you prefer. To find the best deals, simply arrange the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by booking an Expedia package, which combines your Sikeston hotel stay with your flights and activities.
  • Become a One Key member: Join Expedia's One Key membership program for exclusive discounts and deals on hotel bookings. You can also earn OneKeyCash to use on future selected hotels.

Find the best attractions in and around Sikeston

Sikeston, Missouri, offers a charming mix of outdoor activities, scenic views, and romantic spots, perfect for various travelers. Key attractions include urban parks, event venues, and art museums, catering to those seeking culture, business opportunities, and family experiences. For convenient accommodations, consider hotels near the Sikeston Depot Museum and historic downtown Sikeston to enhance your stay.

  • Central Park: Enjoy a family-friendly atmosphere in this urban park, where you can relax outdoors, have a picnic, or take a leisurely stroll. Central Park's city vibes make it a perfect spot for enjoying nature right in the heart of Sikeston.
  • Sikeston Depot Museum: Immerse yourself in local culture at this art museum, where you can explore exhibits that highlight the rich history and heritage of Sikeston. The museum's engaging displays make it a must-visit for art and history enthusiasts.
  • Front Street Studio & Art Gallery: Located 9 miles from Sikeston, this art gallery showcases local creativity and talent. With its vibrant cultural atmosphere, you're sure to find captivating works of art and unique pieces that reflect the area's artistic spirit.

Best time to go to Sikeston

Visitor numbers in Sikeston is generally unchanged in popularity throughout the year. The best time to visit Sikeston is dependant on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are slightly high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are slightly low and weather is mostly sunny with light rain.

calendar iconCalendar Monthtemperature iconTemperaturerain iconPrecipitationmostly cloudy iconCloudinessoccupation rate iconOccupancyprice iconPricing
January36.0°F (2.2°C)Light RainMostly SunnySlightly LowSlightly Low
February39.2°F (4.0°C)Light RainMostly SunnySlightly LowAverage
March49.5°F (9.7°C)Light RainMostly SunnySlightly HighAverage
April58.5°F (14.7°C)Light RainMostly SunnyAverageSlightly High
May68.2°F (20.1°C)Light RainMostly SunnyAverageSlightly High
June77.2°F (25.1°C)Light RainMostly SunnySlightly HighSlightly High
July79.5°F (26.4°C)Light RainMostly SunnySlightly HighAverage
August77.5°F (25.3°C)Light RainMostly SunnyAverageAverage
September72.1°F (22.3°C)Light RainMostly SunnyAverageAverage
October60.8°F (16.0°C)Light RainMostly SunnyAverageAverage
November48.6°F (9.2°C)Light RainMostly SunnyAverageSlightly Low
December41.2°F (5.1°C)Light RainMostly SunnySlightly LowSlightly Low

The nearest major airports for your trip to Sikeston

When planning your trip to Sikeston, Missouri, you have a few airport options. Paducah, KY (PAH-Barkley Regional) is 47 miles away, with nearby hotels like The Respite Bed and Breakfast and Harrah's Metropolis Hotel & Casino. Cape Girardeau, MO (CGI-Cape Girardeau Municipal) is only 24 miles from Sikeston, offering accommodations such as Drury Plaza Hotel and Courtyard by Marriott. Cairo, IL (CIR-Cairo Regional) is also 24 miles away, featuring options like Quality Inn Cairo I-57. Each airport provides convenient access to a variety of hotels, ensuring a comfortable stay as you explore the region.

Frequently asked questions

What is the best area to stay in Sikeston?
Miner is the best area to stay in Sikeston, offering a delightful blend of convenience and charm. This welcoming neighborhood is where most of our travelers choose to stay, thanks to its easy access to local attractions and amenities. You'll find a variety of dining options nearby, from casual eateries to family-friendly restaurants that showcase the region's famous Southern cuisine. The area is also well-connected, making it simple to explore the surrounding attractions, such as the Sikeston Depot Museum or the nearby Bootheel Golf Club.

For families, Miner provides a safe and friendly environment, great for making lasting memories. The close proximity to parks allows for fun-filled afternoons, while spacious rooms cater to larger groups, ensuring everyone is comfortable during their stay.

Couples seeking a relaxing getaway will appreciate the area's serene atmosphere. Enjoy leisurely strolls through local parks or indulge in a romantic dinner at one of the nearby restaurants. The charm of Miner sets the stage for a stress-free and enjoyable experience.
What are the best hotels in Sikeston that travelers recommend?
Drury Inn & Suites Sikeston is a top-rated choice for travelers, boasting an impressive review score of 9.4. This hotel is superb for families and couples alike, offering a inviting space paired with attentive service. Guests appreciate the convenience of both indoor and outdoor pools, making it an excellent spot for relaxation and fun, regardless of the season.
What are the best family hotels in Sikeston?
Drury Inn & Suites Sikeston, MO, is an exceptional choice for families seeking both comfort and convenience. With a guest rating of 9.4, this hotel is designed to cater to the needs of families, offering fantastic amenities that make traveling with children a breeze. Find more child-friendly accommodations in Sikeston.
What hotels in Sikeston offer free breakfast?
Drury Inn & Suites Sikeston, MO, is a top choice for travelers seeking a hotel that offers exceptional service and amenities, all while enjoying a convenient location. With a stellar guest review rating of 9.4, this hotel ensures a friendly setting for families and solo travelers alike. Find more hotels with free breakfast in Sikeston.
What are the top pet-friendly hotels in Sikeston?
Drury Inn & Suites in Sikeston, MO, is an excellent choice for travelers seeking a pet-friendly experience without compromising on comfort and convenience. With a stellar review score of 9.4, guests rave about the warm hospitality and thoughtful amenities that make every stay enjoyable. See more pet-friendly hotels in Sikeston.
What are the best budget hotels in Sikeston?
Pear Tree Inn Sikeston is a fantastic choice for budget-conscious travelers looking for a comfortable stay without compromising on amenities. With a stellar rating of 9.4, this hotel offers an inviting indoor and outdoor pool, superb for family fun or relaxation. Guests appreciate the complimentary breakfast, which is available on weekends, and the free toiletries, ensuring a straightforward experience. Plus, families can enjoy the convenience of cribs at no extra charge.

Another excellent option is the Drury Inn & Suites Sikeston, also boasting a customer review rating of 9.4. This hotel features an array of amenities, including both indoor and outdoor pools, and a delicious buffet breakfast that is free for all guests. Families will find value in the spacious rooms equipped with sofa beds, as well as the free long-distance calls and WiFi, making it easy to stay connected during your travels.

For travelers, the Hampton Inn Sikeston, rated 8.8, offers a cozy atmosphere with an accessible fitness center and a welcoming indoor pool. This hotel is superb for couples seeking a comfortable retreat while still enjoying the convenience of complimentary breakfasts and free WiFi.

Whether you're traveling with family or as a couple, Sikeston has budget-friendly hotels that cater to your needs while ensuring a pleasant stay. View all budget hotels in Sikeston.
When is the best time to go to Sikeston?
The most popular time to visit Sikeston is during the spring months, particularly in April when the weather begins to warm up and the natural beauty of the area comes to life. With average temperatures ranging from the mid-50s to low 70s Fahrenheit, it's an inviting season for outdoor activities and exploration.

As you consider your travel plans, keep in mind that peak tourist season typically spans from late spring to early fall, particularly from May through September. This period is characterized by vibrant festivals, local events, and a lively atmosphere as visitors flock to enjoy the charm of Sikeston. The warm weather is superb for enjoying the outdoors, whether you're taking a leisurely stroll through the town's parks or indulging in the famous local cuisine at outdoor dining spots.

For those who appreciate a more tranquil experience, visiting during late fall, particularly in November, can offer a wonderful opportunity to explore Sikeston without the hustle and bustle. With fewer tourists around, you can take your time discovering the area's rich history and culture, including the renowned Sikeston Rodeo, which typically takes place in the early fall months.
Where can I find the best nightlife in Sikeston?
Sikeston is a charming town that offers a laid-back atmosphere, but its nightlife options are more limited compared to larger cities.

The downtown area features a few local bars and pubs where you can unwind after a day of exploring. Places like the Sikeston Jaycee's Fairgrounds often host events and gatherings, providing a sense of community and casual entertainment.

If you're looking for a more lively experience, consider visiting nearby towns such as Cape Girardeau or Poplar Bluff, which offer a broader selection of nightlife options, including live music venues and dance clubs.
Can I cancel my hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline -- this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Sikeston hotel for you.
How can I save on a Sikeston hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Sikeston hotel bookings for every dollar you spend -- just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Sikeston hotel?
Prices for hotels in Sikeston often vary, but you can find a great deal from $75 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.