Top 10 Hotels in Sikeston

See all 35 Hotels in Sikeston
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO

2608 East Malone Ave, Sikeston 63801

3.0 out of 5.0
4.6 out of 5 (322 reviews)

Located in the heart of Sikeston, this hotel is 0.2 mi (0.3 km) from The Book Bug and within 6 mi (10 km) of Sikeston Depot …

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Best Western Plus Sikeston
Best Western Plus Sikeston

120 S Interstate Drive, Sikeston 63801

2.5 out of 5.0
4.3 out of 5 (293 reviews)

Situated in Sikeston, this hotel is 0.8 mi (1.2 km) from The Book Bug and within 6 mi (10 km) of Sikeston Depot Museum and …

$93
Pear Tree Inn - Sikeston
Pear Tree Inn - Sikeston

2602 E Malone Avenue, Sikeston 63801

2.5 out of 5.0
4.3 out of 5 (327 reviews)

Located in the heart of Sikeston, this hotel is 0.2 mi (0.3 km) from The Book Bug and 3.1 mi (5 km) from Sikeston Depot Museu …

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Comfort Inn And Suites
Comfort Inn And Suites

109 Matthews Ln, Sikeston 63801

2.5 out of 5.0
4.2 out of 5 (40 reviews)

Located in the heart of Sikeston, this hotel is 0.6 mi (0.9 km) from The Book Bug and within 6 mi (10 km) of Sikeston Depot …

$81
Motel 6 Sikeston MO
Motel 6 Sikeston MO

110 S Interstate Dr, Sikeston 63801

2.0 out of 5.0
3 out of 5 (122 reviews)

Situated in Sikeston, this motel is 0.6 mi (1 km) from The Book Bug and within 6 mi (10 km) of Sikeston Depot Museum and Boot …

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Super 8 - Sikeston/Miner Area
Super 8 - Sikeston/Miner Area

2609 E Malone Ave, Sikeston 63801

2.0 out of 5.0
3 out of 5 (172 reviews)

Situated in Sikeston, this hotel is 0.2 mi (0.4 km) from The Book Bug and within 3 mi (5 km) of Sikeston Depot Museum and Boo …

$54
Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau West

103 Cape West Pkwy, Cape Girardeau 63701

2.5 out of 5.0
4.2 out of 5 (154 reviews)

Located in the heart of Cape Girardeau, this hotel is 2.8 mi (4.4 km) from Cape Splash Family Aquatic Center and within 6 mi …

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Holiday Inn Express & Suites Sikeston Southwest
Holiday Inn Express & Suites Sikeston Southwest

115 Hospitality Dr, Sikeston 63801

2.5 out of 5.0
4.3 out of 5 (43 reviews)

Situated in a rural location, this hotel is 1 mi (1.7 km) from Central Park and 1.4 mi (2.3 km) from Sikeston Depot Museum. …

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Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau Near the Medical Center

3248 William St, Cape Girardeau 63701

2.0 out of 5.0
4 out of 5 (413 reviews)

Located in the heart of Cape Girardeau, this hotel is 2.2 mi (3.6 km) from Cape Splash Family Aquatic Center and 2.9 mi (4. …

$70
Oak Tree Inn Dexter
Oak Tree Inn Dexter

1608 Hwy Business 60 W, Dexter 63841

2.5 out of 5.0
3.8 out of 5 (123 reviews)

Situated in Dexter, this hotel is within 3 mi (5 km) of The Heritage House, Dexter Welcome Center Depot and Museum, and Kelle …

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Where to stay in Sikeston

Sikeston Hotel Guide

So, are you vacationing in Southeast Missouri and are looking to choose a room in Sikeston? You'll find 9 Expedia-listed hotels and apartments within a 0.1-mile distance of the downtown area.

Looking for somewhere to stay in 2 miles of the heart of Sikeston? Days Inn Sikeston and Holiday Inn Express & Suites Sikeston Southwest will fit the bill.

Cape Girardeau is another Sikeston neighborhood that has lodgings. You could also check out Dexter and Jackson. If you opt to stay in Cape Girardeau, you can choose from the Auburn Place Hotel And Suites and Hampton Inn Cape Girardeau I 55 East. Alternatively, those who choose to base themselves in Dexter, can choose between the Oak Tree Inn Dexter and Econo Lodge Dexter. In Jackson visitors can choose from Comfort Suites Jackson-Cape Girardeau and Town House Inn.

The Auburn Place Hotel And Suites is conveniently located 30 miles from downtown Sikeston and is ideal for visitors who are watching their pennies. The Oak Tree Inn Dexter is another no-frills option here.

The Comfort Inn And Suites is situated 3 miles away from the center of Sikeston. Another option is the Quality Inn Charleston, which is located 13 miles away. The Americas Best Value Inn & Suites Sikeston and the Super 8 - Sikeston/Miner Area are alternative places to book accommodation around Sikeston.

Hayti is 45 miles to the south of Sikeston and is where you'll find Hayti Pentecostal Holiness Church and Hayti Park. If you'd like to stay in Hayti, check out the room rates at the Comfort Inn Hayti and Drury Inn & Suites Hayti Caruthersville. 60 miles to the north of Sikeston, you may also choose to stay at Perryville, home to the Super 8 Perryville and Days Inn Perryville. While visiting Perryville, you might like to visit the National Shrine of Our Lady of the Miraculous Medal and Perryville Country Club.

Sikeston is home to some terrific things to see and do; learn more at Expedia's up-to-date Sikeston travel guide.