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Find Hotels in Sikeston, MO

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Sikeston hotels and places to stay

Eagle Inn Charleston
2 out of 5
2811 East Marshall Street, Charleston, MO
Free CancellationReserve now, pay when you stay
The price is $58 per night
15.84 mi from city center
3.4/5 (59 reviews)

"Overall it was ok for the location room was clean bed comfy"…"

Reviewed on Dec 16, 2019

Eagle Inn Charleston
Pear Tree Inn Sikeston
2.5 out of 5
2602 E Malone Avenue, Sikeston, MO
Free CancellationReserve now, pay when you stay
The price is $85 per night
3.06 mi from city center
4.5/5Wonderful! (860 reviews)

"Very nice stay... free drinks was a nice touch! (Didn't like that no one reminded me to take my water mug:o)"…"

Reviewed on Jul 21, 2020

Pear Tree Inn Sikeston
Drury Inn & Suites Sikeston, MO
3 out of 5
2608 East Malone Ave, Sikeston, MO
Free CancellationReserve now, pay when you stay
The price is $95 per night
3.11 mi from city center
4.6/5Exceptional! (767 reviews)

"Amazing team. Friendly and great bkf."…"

Reviewed on Jul 28, 2020

Drury Inn & Suites Sikeston, MO
Best Western Plus Sikeston
2.5 out of 5
120 S Interstate Drive, Sikeston, MO
Free CancellationReserve now, pay when you stay
The price is $84 per night
3.35 mi from city center
4.2/5Excellent! (643 reviews)

"It was ok. The beds were uncomfortable, there was a dirty towel in the bathroom and a dirty ball under the ac unit. But the staff was amazing and very helpful."…"

Reviewed on Jun 28, 2020

Best Western Plus Sikeston
Travel Inn & Suites
2.5 out of 5
100 Matthews Lane, Sikeston, MO
Free CancellationReserve now, pay when you stay
The price is $54 per night
3.07 mi from city center
3.9/5Very Good! (89 reviews)

"I really enjoyed my stay here. I come to Sikeston to visit my mom at a nursing home. I have to stand outside her window to talk to her, a couple of times a visit. So, having very nice people working at a very nice, newly remodeled hotel room helps so much. Plus, they allow my dog. Right now not having ..."…"

Reviewed on May 26, 2020

Travel Inn & Suites
Days Inn and Suites by Wyndham Sikeston
2 out of 5
220 S Interstate Dr, Sikeston, MO
Free CancellationReserve now, pay when you stay
The price is $58 per night
3.34 mi from city center
3.6/5Good! (590 reviews)

"Always a pleasant stay here half way to our destination."…"

Reviewed on Mar 15, 2020

Days Inn and Suites by Wyndham Sikeston
Super 8 by Wyndham Charleston MO
2 out of 5
310 S Story St, Charleston, MO
Free CancellationReserve now, pay when you stay
The price is $50 per night
14.96 mi from city center
3.4/5Good! (290 reviews)

"Good location near state border /gas. Clean room. Minor repairs needed. No breakfast during pandemic. Third time I’ve stayed here - front desk friendly, but scattered."…"

Reviewed on Jul 16, 2020

Super 8 by Wyndham Charleston MO
Super 8 by Wyndham Sikeston/Miner Area
2 out of 5
2609 E Malone Ave, Sikeston, MO
Free CancellationReserve now, pay when you stay
The price is $54 per night
2.87 mi from city center
3.1/5 (367 reviews)
good Joint to stay

"Nice place staff was good to"…"

Reviewed on Mar 7, 2020

Super 8 by Wyndham Sikeston/Miner Area
Hampton Inn Sikeston
2.5 out of 5
1240 Commerce Drive, Sikeston, MO
Free CancellationReserve now, pay when you stay
The price is $93 per night
1.46 mi from city center
4.6/5Wonderful! (68 reviews)

"Friendly staff and clean rooms. Easy check in and good breakfast 🍳"…"

Reviewed on Jul 29, 2020

Hampton Inn Sikeston
Holiday Inn Express & Suites Sikeston Southwest
2.5 out of 5
115 Hospitality Dr, Sikeston, MO
Free Cancellation
The price is $85 per night
1.37 mi from city center
4.4/5Wonderful! (166 reviews)

"The staff was very friendly and helpful. We were pleased with our accommodations."…"

Reviewed on Aug 10, 2020

Holiday Inn Express & Suites Sikeston Southwest
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Visiting Sikeston

Families will find kid-friendly activities in Sikeston, and visitors give high marks for the top-notch restaurants and shopping. This welcoming city also attracts tourists with its riverfront and university setting. Top sights in the city include Isle Casino Cape Girardeau and Shawnee National Forest.

  • There are 39 hotels and other accommodations in Sikeston
  • The closest major airport is in Cairo, IL (CIR-Cairo Regional), 23.8 mi (38.3 km) from the city center
  • The next closest is in Cape Girardeau, MO (CGI-Cape Girardeau Municipal), 24.2 mi (38.9 km) away

Sightseeing and Staying in Sikeston

The city's cultural venues include Sikeston Depot Museum and Dexter Welcome Center Depot and Museum. Families come for attractions such as Cape Splash Family Aquatic Center, Cape Girardeau Conservation Nature Center, and Lazy L Safari Park. Notable city landmarks like The Heritage House and Keller Veteran Memorial might be worth a visit.

As you plan your holiday getaway, you'll find 39 hotels and other lodging options to choose from in Sikeston. Below are top ranked ones based on Expedia user reviews:

  • Hampton Inn Cape Girardeau I 55 East - This 2.5-star hotel features free breakfast, an indoor pool, and free WiFi. It's a favorite with Expedia travelers for its clean, comfortable rooms and room size.
  • Holiday Inn Express Hotel & Suites Cape Girardeau I-55 - Our customers like the overall value and clean, comfortable rooms at this hotel. With a stay at this 2.5-star hotel, guests can enjoy access to an indoor pool and free parking, along with free WiFi.
  • Drury Inn & Suites Cape Girardeau - This 3-star hotel features free breakfast, an indoor pool, and free WiFi. Expedia customers like its helpful staff and comfortable rooms.

Other top sights in Sikeston include Isle Casino Cape Girardeau and Shawnee National Forest.

Dressing for Sikeston

  • Between January and March, you can expect average temperatures of 65°F during the day and 27°F at night
  • From April to June, the average during the day is 91°F, while the average at night is 44°F
  • July through September has daytime averages of 92°F with nighttime averages of 54°F
  • In October-December, you can expect daytime averages of 78°F and nighttime averages of 28°F
  • Sikeston gets about 49.33 inches of rain per year
  • Usually July and August are the hottest months with an average of 91°F, whereas January and December are often coldest, averaging 30°F

Frequently asked questions

Where is the best place to stay in Sikeston?
Drury Plaza Hotel Cape Girardeau Conference Center is ranked highly by Expedia customers. This 3-star hotel offers free breakfast and a restaurant. Other top choices based on reviews include Hampton Inn Cape Girardeau I 55 East and Holiday Inn Express Hotel & Suites Cape Girardeau I-55.
If I need to cancel my hotel reservation in Sikeston, will I receive a refund?
Yes! You’ll find that most hotel bookings are fully refundable as long as you cancel before the accommodation’s cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that’s non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of your booking. Enter your dates, click on “Search”, then use the filter option “free cancellation” to view the top deals on offer in Sikeston.
Where can I learn more about changing or cancelling my trip to Sikeston?
For more details about changing or cancelling your trip to Sikeston, head over to our customer service page.
What's the best budget-friendly hotel in Sikeston?
Based on reviews, Auburn Place Hotel And Suites is a popular 2.5-star hotel for our travelers looking for an economical choice, and features free buffet breakfast and free WiFi. Other options to stay on the cheap include Pear Tree Inn Sikeston and Pear Tree Inn Cape Girardeau West.
What's the best hotel for a family vacation in Sikeston?
Pear Tree Inn Sikeston is a hotel with an outdoor pool and free breakfast, and it’s a top choice on Expedia for families. Other good options to stay with the kids include Auburn Place Hotel And Suites and Drury Inn & Suites Sikeston, MO. Attractions like Cape Girardeau Conservation Nature Center and Lazy L Safari Park are also fun for kids of all ages.
What's the best pet-friendly accommodation in Sikeston?
Auburn Place Hotel And Suites is a top hotel for people traveling with their pets, and offers an indoor pool and a fitness center for its human guests. Other good options for you and your pet’s trip include Drury Inn & Suites Sikeston, MO and Pear Tree Inn Sikeston.
Where is the best hotel to stay close to Isle Casino Cape Girardeau?
Pear Tree Inn Cape Girardeau West is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and free WiFi. It’s located 3.5 mi (5.6 km) from Isle Casino Cape Girardeau. Other good options within a few miles include Auburn Place Hotel And Suites and Pear Tree Inn Cape Girardeau Near the Medical Center.
What about the best place to stay close to The Book Bug?
One of the top choices for your stay is Pear Tree Inn - Sikeston, located next to The Book Bug, and this hotel offers free breakfast and an outdoor pool. Drury Inn & Suites Sikeston, MO and Best Western Plus Sikeston are two other good choices in the immediate area.
What's the best hotel for a golf vacation in Sikeston?
Travel Inn & Suites is a hotel featuring free WiFi and free Internet, and it’s a top choice for playing a round of golf. You can tee off at Boot Heel Golf Club during your trip.
What are some accommodations with pools in Sikeston?
Auburn Place Hotel And Suites is a top hotel with an indoor pool, free buffet breakfast, and free WiFi. A couple of other options that feature an onsite pool include Pear Tree Inn Sikeston and Drury Inn & Suites Sikeston, MO.

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