Top 10 Hotels in Sikeston

See all 27 Hotels in Sikeston
Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau Near the Medical Center

3248 William St, Cape Girardeau 63701

2.0 out of 5.0
4 out of 5 (393 reviews)

Located in the heart of Cape Girardeau, this hotel is 2.2 mi (3.6 km) from Cape Splash Family Aquatic Center and within 6 mi …

$90
Pear Tree Inn - Sikeston
Pear Tree Inn - Sikeston

2602 E Malone Avenue, Sikeston 63801

2.5 out of 5.0
4.2 out of 5 (279 reviews)

Located in the heart of Sikeston, this hotel is 3.1 mi (5 km) from Sikeston Depot Museum and within 6 mi (10 km) of Boot Heel …

$80
Days Inn Sikeston
Days Inn Sikeston

1330 S Main St, Sikeston 63801

2.0 out of 5.0
2.8 out of 5 (208 reviews)

Situated in Sikeston, this hotel is 1.1 mi (1.8 km) from Central Park and 1.5 mi (2.5 km) from Sikeston Depot Museum. Boot …

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Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO

2608 East Malone Ave, Sikeston 63801

3.0 out of 5.0
4.7 out of 5 (290 reviews)

Located in the heart of Sikeston, this hotel is within 6 mi (10 km) of Sikeston Depot Museum, Boot Heel Golf Club, and …

$115
Candlewood Suites Cape Girardeau
Candlewood Suites Cape Girardeau

485 S Mount Auburn Rd, Cape Girardeau 65703

2.5 out of 5.0
4.4 out of 5 (183 reviews)

Situated in Cape Girardeau, this hotel is 3 mi (4.9 km) from Cape Splash Family Aquatic Center and within 6 mi (10 km) of …

$116
Quality Inn Charleston
Quality Inn Charleston

102 Drake St, Charleston 63834

2.0 out of 5.0
3.7 out of 5 (54 reviews)

Situated in Charleston, this hotel is within 20 mi (32 km) of Central Park, Fort Defiance, and Sikeston Depot Museum. Boot …

$70
Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau West

103 Cape West Pkwy, Cape Girardeau 63701

2.5 out of 5.0
4.1 out of 5 (121 reviews)

Located in the heart of Cape Girardeau, this hotel is 2.8 mi (4.4 km) from Cape Splash Family Aquatic Center and within 6 mi …

$80
Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MO

225 Drury Lane, Jackson 63755

3.0 out of 5.0
4.7 out of 5 (192 reviews)

Located in the heart of Jackson, this hotel is within 6 mi (10 km) of Steele Crest Winery, Lazy L Safari Park, and Litz Park …

$105
Country Hearth Inn And Suites Sikeston
Country Hearth Inn And Suites Sikeston

100 Matthews Ln, Sikeston 63801

2.8 out of 5 (26 reviews)

Situated in a rural location, this hotel is within 6 mi (10 km) of Sikeston Depot Museum, Boot Heel Golf Club, and Central …

$54
Best Western Plus Sikeston
Best Western Plus Sikeston

120 S Interstate Drive, Sikeston 63801

2.5 out of 5.0
4.3 out of 5 (248 reviews)

Situated in Sikeston, this hotel is within 6 mi (10 km) of Sikeston Depot Museum, Boot Heel Golf Club, and Central Park …

$90

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Where to stay in Sikeston

Sikeston Hotel Guide

Are you arranging to book some nights in Southeast Missouri? Hoping to book accommodation in the Sikeston area? There are 4 hotels and apartments here that should satisfy your needs.

There are only a small number hotels to choose from within easy walking distance from the center of Sikeston. The Days Inn Sikeston is an ideal option as it's only 2 miles away.

3 miles from the center of Sikeston, is the Comfort Inn And Suites. The Quality Inn Charleston is positioned 13 miles away. Some other hotel and apartment options around this area include the Americas Best Value Inn & Suites Sikeston and the Super 8 Motel - Sikeston/Miner Area.

Situated 60 miles to the south of Sikeston is Perryville, which boasts a variety of Expedia-listed hotels and apartments. The Super 8 Perryville and Days Inn Perryville are a selection of the hotels here.

Our destination page is a great way to discover more about Sikeston.