Top 10 Hotels in Sikeston

See all 27 Hotels in Sikeston
Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau Near the Medical Center

3248 William St, Cape Girardeau 63701

2.0 out of 5.0
4 out of 5 (391 reviews)

Located in the heart of Cape Girardeau, this hotel is 2.2 mi (3.6 km) from Cape Splash Family Aquatic Center and within 6 mi …

$100
Holiday Inn Express Hotel & Suites Cape Girardeau I-55
Holiday Inn Express Hotel & Suites Cape Girardeau I-55

3253 William Street, Cape Girardeau 63701

2.5 out of 5.0
4.8 out of 5 (264 reviews)

Situated in a rural location, this hotel is 2.2 mi (3.6 km) from Cape Splash Family Aquatic Center and within 6 mi (10 km) of …

$129
Days Inn Sikeston
Days Inn Sikeston

1330 S Main St, Sikeston 63801

2.0 out of 5.0
2.8 out of 5 (204 reviews)

Situated in Sikeston, this hotel is 1.1 mi (1.8 km) from Central Park and 1.5 mi (2.5 km) from Sikeston Depot Museum. Boot …

$55
Super 8 Charleston MO
Super 8 Charleston MO

310 S Story St, Charleston 63834

2.0 out of 5.0
3.5 out of 5 (91 reviews)

Located in the heart of Charleston, this motel is within 20 mi (32 km) of Fort Defiance, Central Park, and Sikeston Depot …

$64
Pear Tree Inn - Sikeston
Pear Tree Inn - Sikeston

2602 E Malone Avenue, Sikeston 63801

2.5 out of 5.0
4.2 out of 5 (267 reviews)

Located in the heart of Sikeston, this hotel is 3.1 mi (5 km) from Sikeston Depot Museum and within 6 mi (10 km) of Boot Heel …

$85
Quality Inn Charleston
Quality Inn Charleston

102 Drake St, Charleston 63834

2.0 out of 5.0
3.8 out of 5 (51 reviews)

Situated in Charleston, this hotel is within 20 mi (32 km) of Central Park, Fort Defiance, and Sikeston Depot Museum. Boot …

$77
Eagle Inn Charleston
Eagle Inn Charleston

2811 East Marshall Street, Charleston 63834

2.0 out of 5.0
2.9 out of 5 (16 reviews)

Situated in a rural location, this motel is within 20 mi (32 km) of Central Park, Sikeston Depot Museum, and Boot Heel Golf …

$50
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO

2608 East Malone Ave, Sikeston 63801

3.0 out of 5.0
4.7 out of 5 (285 reviews)

Located in the heart of Sikeston, this hotel is within 6 mi (10 km) of Sikeston Depot Museum, Boot Heel Golf Club, and …

$120
Candlewood Suites Cape Girardeau
Candlewood Suites Cape Girardeau

485 S Mount Auburn Rd, Cape Girardeau 65703

2.5 out of 5.0
4.4 out of 5 (182 reviews)

Situated in Cape Girardeau, this hotel is 3 mi (4.9 km) from Cape Splash Family Aquatic Center and within 6 mi (10 km) of …

$104
Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau West

103 Cape West Pkwy, Cape Girardeau 63701

2.5 out of 5.0
4.1 out of 5 (116 reviews)

Located in the heart of Cape Girardeau, this hotel is 2.8 mi (4.4 km) from Cape Splash Family Aquatic Center and within 6 mi …

$85

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Where to stay in Sikeston

Sikeston Hotel Guide

Are you arranging to book some nights in Southeast Missouri? Hoping to book accommodation in the Sikeston area? There are 4 hotels and apartments here that should satisfy your needs.

There are only a small number hotels to choose from within easy walking distance from the center of Sikeston. The Days Inn Sikeston is an ideal option as it's only 2 miles away.

3 miles from the center of Sikeston, is the Comfort Inn And Suites. The Quality Inn Charleston is positioned 13 miles away. Some other hotel and apartment options around this area include the Americas Best Value Inn & Suites Sikeston and the Super 8 Motel - Sikeston/Miner Area.

Situated 60 miles to the south of Sikeston is Perryville, which boasts a variety of Expedia-listed hotels and apartments. The Super 8 Perryville and Days Inn Perryville are a selection of the hotels here.

Our destination page is a great way to discover more about Sikeston.