Title: Top 10 Hotels in Chaffee, MO from $65 - Competitive Prices | Expedia.com [Vacation Rentals in Chaffee](https://expedia.com/Chaffee-Vacation-Rentals.d553248634983269107.Travel-Guide-VacationRentals)[Car Rentals in Chaffee](https://expedia.com/Car-Rentals-In-Chaffee.d553248634983269107.Car-Rental-Guide)[Chaffee Vacation Packages](https://expedia.com/Chaffee.d553248634983269107.Destination-Travel-Guides) ![Some call it middle of nowhere, I call it home ❤️](https://images.trvl-media.com/place/553248634983269107/13e31245-382d-465b-a415-fb3e2cf47f66.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Bailey Swinford ![](https://images.trvl-media.com/place/553248634983269107/13e31245-382d-465b-a415-fb3e2cf47f66.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Chaffee Pool [](https://www.expedia.com/Hotel-Search?destination=Chaffee%2C+Missouri%2C+United+States+of+America®ionId=553248634983269107&latLong=37.180051%2C-89.65509&adults=2&startDate=2026-02-28&d1=2026-02-28&endDate=2026-03-02&d2=2026-03-02&amenities=POOL) Pet-friendly [](https://www.expedia.com/Hotel-Search?destination=Chaffee%2C+Missouri%2C+United+States+of+America®ionId=553248634983269107&latLong=37.180051%2C-89.65509&adults=2&startDate=2026-02-28&d1=2026-02-28&endDate=2026-03-02&d2=2026-03-02&amenities=PETS) Great for families [](https://www.expedia.com/Hotel-Search?destination=Chaffee%2C+Missouri%2C+United+States+of+America®ionId=553248634983269107&latLong=37.180051%2C-89.65509&adults=2&startDate=2026-02-28&d1=2026-02-28&endDate=2026-03-02&d2=2026-03-02&travelerType=family_friendly) Apart­ment [](https://www.expedia.com/Hotel-Search?destination=Chaffee%2C+Missouri%2C+United+States+of+America®ionId=553248634983269107&latLong=37.180051%2C-89.65509&adults=2&startDate=2026-02-28&d1=2026-02-28&endDate=2026-03-02&d2=2026-03-02&lodging=APARTMENT) Waterpark [](https://www.expedia.com/Hotel-Search?destination=Chaffee%2C+Missouri%2C+United+States+of+America®ionId=553248634983269107&latLong=37.180051%2C-89.65509&adults=2&startDate=2026-02-28&d1=2026-02-28&endDate=2026-03-02&d2=2026-03-02&amenities=WATER_PARK) ## Check prices for these dates Tonight [Feb 14 - Feb 15](https://www.expedia.com/Hotel-Search?regionId=553248634983269107&startDate=2026-02-14&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 15 - Feb 16](https://www.expedia.com/Hotel-Search?regionId=553248634983269107&startDate=2026-02-15&endDate=2026-02-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 20 - Feb 22](https://www.expedia.com/Hotel-Search?regionId=553248634983269107&startDate=2026-02-20&endDate=2026-02-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Feb 27 - Mar 1](https://www.expedia.com/Hotel-Search?regionId=553248634983269107&startDate=2026-02-27&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Chaffee hotels ![Lobby](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/5950187f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Suite, 2 Bedrooms, Non Smoking, Garden View | Free WiFi](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/fd5c34e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/9f324b7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/a236a8e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rockwood Inn [](https://www.expedia.com/Cape-Girardeau-Hotels-Rockwood-Inn.h105486893.Hotel-Information) Cape Girardeau 10/10 Exceptional (19 reviews) "My stay was cozy, warm and inviting, and absolutely wonderful shower. I will definitely be returning! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kim $150 nightly $170 total Mar 1 - Mar 2 Total with taxes and fees [](https://www.expedia.com/Cape-Girardeau-Hotels-Rockwood-Inn.h105486893.Hotel-Information) ![Desk, free WiFi](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/c3f8959c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/464a0039.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/f2b68c48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking (NRF) | Desk, free WiFi](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/1f46462a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Town House Inn Cape Giradreau [](https://www.expedia.com/Sikeston-Hotels-Town-House-Inn-Cape-Giradreau.h11613884.Hotel-Information) Cape Girardeau 6.2/10 (210 reviews) "Along a main street but not a lot of noise, especially in the rooms. Rooms exit to the outdoors." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gary $62 nightly $70 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Town-House-Inn-Cape-Giradreau.h11613884.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/6afa6c85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/f7d52bda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/c3df8884.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/75079b79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Candlewood Suites Cape Girardeau by IHG [](https://www.expedia.com/Sikeston-Hotels-Candlewood-Suites-Cape-Girardeau.h3530303.Hotel-Information) Cape Girardeau 8.2/10 Very Good (895 reviews) "Room was clean and spacious." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) George $80 nightly $96 total Feb 22 - Feb 23 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Candlewood-Suites-Cape-Girardeau.h3530303.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/75000000/74670000/74660800/74660768/a0829ae4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/75000000/74670000/74660800/74660768/145de6a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/75000000/74670000/74660800/74660768/ac6df1a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/75000000/74670000/74660800/74660768/c0aef459.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### EC Reed's Mercantile and Hotel [](https://www.expedia.com/Marble-Hill-Hotels-EC-Reeds-Mercantile-And-Hotel.h74660768.Hotel-Information) Marble Hill 9.6/10 Exceptional (84 reviews) "Cute room, great food, fun soda fountain and friendly owners! Will return! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leslie $102 nightly $112 total Feb 25 - Feb 26 Total with taxes and fees [](https://www.expedia.com/Marble-Hill-Hotels-EC-Reeds-Mercantile-And-Hotel.h74660768.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/6966efed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/84598bf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed, Accessible (Sofa Sleeper, Tub, 2 Rooms) | Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/0f190cb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/ffb58563.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Cape Girardeau [](https://www.expedia.com/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) Cape Girardeau 9.4/10 Exceptional (1,002 reviews) "Awesome stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Breckin $89 nightly $101 total Feb 22 - Feb 23 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/dc836bc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/44b66206.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking | Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/4ac4ba46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Cape Girardeau North [](https://www.expedia.com/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) Cape Girardeau 7.2/10 Good (698 reviews) "The room was clean and nice. The breakfast was really good." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kalani $58 nightly $65 total Feb 26 - Feb 27 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) ![Snack bar](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/2f374258.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/2e166a9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible, Bathtub (Mobility & Hearing)](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/1ca0c293.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/5aa6a52b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Cape Girardeau [](https://www.expedia.com/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) Cape Girardeau 9.6/10 Exceptional (109 reviews) "It was a nice stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Douglas $89 nightly $102 total Feb 24 - Feb 25 Total with taxes and fees [](https://www.expedia.com/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/8bb15ffe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/266a85bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/51a3fe78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/ac6f4af6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Cape Girardeau [](https://www.expedia.com/Cape-Girardeau-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Girardeau.h99972043.Hotel-Information) Cape Girardeau 9.4/10 Exceptional (158 reviews) "Great hotel - super clean, fast check-in, convenient, etc. We’ll definitely stay here again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Richard $93 nightly $105 total Feb 22 - Feb 23 Total with taxes and fees [](https://www.expedia.com/Cape-Girardeau-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Girardeau.h99972043.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/e6e29f10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/81fbb6f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/b20a49e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave | In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/051de21c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Cape Girardeau I 55 East [](https://www.expedia.com/Sikeston-Hotels-Hampton-Inn-Cape-Girardeau-I-55-East.h12786627.Hotel-Information) Cape Girardeau 9.6/10 Exceptional (791 reviews) "Excellent stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christina $106 nightly $119 total Feb 22 - Feb 23 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Hampton-Inn-Cape-Girardeau-I-55-East.h12786627.Hotel-Information) ![Desk, laptop workspace, blackout drapes, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/71011e95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible (Tub) | Desk, laptop workspace, blackout drapes, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/86c003aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/dba6fd48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/f71e5ca6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Cape Girardeau West [](https://www.expedia.com/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) Cape Girardeau 9.0/10 Wonderful (1,003 reviews) "The staff were all very friendly. The room was clean and the beds were nice. Bathroom was very clean and comfortable " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Fred $72 nightly $81 total Feb 19 - Feb 20 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Grand Riverview Two Queen Room | Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/8ba17328.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/53cb7546.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/f27091ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Riverview [](https://www.expedia.com/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) Cape Girardeau 9.4/10 Exceptional (502 reviews) "The room was clean and I was able to check in a bit early." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sara $93 nightly $105 total Feb 16 - Feb 17 Total with taxes and fees [](https://www.expedia.com/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/927db718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/18325925.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/ae49c8da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/c7d69739.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Cape Girardeau Downtown [](https://www.expedia.com/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) Cape Girardeau 9.6/10 Exceptional (488 reviews) "Very nice hotel!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angie $125 nightly $142 total Feb 26 - Feb 27 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/5929e46c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/db8c9491.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/c65fb6ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/16f1820b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Plaza Hotel Cape Girardeau Conference Center [](https://www.expedia.com/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) Cape Girardeau 9.6/10 Exceptional (1,004 reviews) "Great place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kelly $99 nightly $112 total Feb 22 - Feb 23 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Economy Single Room, 1 Queen Bed, Kitchenette | Private kitchen | Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/2ba6efa1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/2abc797b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/ef0f7e68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Room, Accessible, Kitchenette | Bathroom | Hair dryer, towels](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/46ce3d10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Town House Inn [](https://www.expedia.com/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) Jackson 7.6/10 Good (435 reviews) "The staff member Tim was very friendly and nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julie $68 nightly $74 total Mar 9 - Mar 10 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free breakfast](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/5fa70c20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom (Feature) | Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/40930878.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8 AM to 11 PM, sun loungers](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/64fb9857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG [](https://www.expedia.com/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) Cape Girardeau 9.4/10 Exceptional (1,001 reviews) "Breakfast was very good and staff was extremely friendly and rooms were very clean " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rex $95 nightly $107 total Feb 22 - Feb 23 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/06dc4487.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/8a502333.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/0ac4753f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/eec0e02a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Jackson-Cape Girardeau [](https://www.expedia.com/Sikeston-Hotels-Comfort-Suites-Jackson-Cape-Girardeau.h2555896.Hotel-Information) Jackson 8.2/10 Very Good (741 reviews) "Clean and comfortable every time. This is a “go to” hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jacqulyn $84 nightly $91 total Feb 22 - Feb 23 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Comfort-Suites-Jackson-Cape-Girardeau.h2555896.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/47fa1edf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/dc7dee1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/23518830.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily self-serve breakfast](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/8447c54f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau [](https://www.expedia.com/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) Jackson 9.0/10 Wonderful (704 reviews) "Conveniently located, clean, friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Philip $84 nightly $91 total Feb 17 - Feb 18 Total with taxes and fees [](https://www.expedia.com/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/85184a8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/f90ef358.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/978331d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/95135562.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Sikeston, MO [](https://www.expedia.com/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) Sikeston 9.4/10 Exceptional (1,000 reviews) "As always it was a perfect visit" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John $93 nightly $107 total Feb 22 - Feb 23 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/fa4ef12a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/3798eaf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/b7350700.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/980dd49e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Yard Inn and Suite [](https://www.expedia.com/Sikeston-Hotels-Country-Yard-Inn-And-Suite.h90821467.Hotel-Information) Sikeston 6.6/10 (122 reviews) "Great spot en route home from Mississippi. Staff put me in a room that ended up being in a quiet section of the hotel. Great sleep." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrew $48 nightly $54 total Feb 15 - Feb 16 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Country-Yard-Inn-And-Suite.h90821467.Hotel-Information) ![1 bedroom, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/be0d2e33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/7335ffbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/717baff4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/8fe9a2cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn and Suites by Wyndham Sikeston [](https://www.expedia.com/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) Sikeston 7.2/10 Good (1,001 reviews) "Everything was excellent" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James $68 nightly $78 total Feb 16 - Feb 17 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-02-28&endDate=2026-03-01®ionId=553248634983269107&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=HTG_SPRING_PROMO_553248634983269107) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FChaffee-Hotels.d553248634983269107.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FChaffee-Hotels.d553248634983269107.Travel-Guide-Hotels) ## Learn more about Chaffee Venture to Isle Casino Cape Girardeau and Show Me Center—just two of the sights around Chaffee. [See all hotels in Chaffee](https://www.expedia.com/Hotel-Search?startDate=2026-02-28&endDate=2026-03-01&adults=2®ionId=553248634983269107) ![Some call it middle of nowhere, I call it home ❤️](https://images.trvl-media.com/place/553248634983269107/13e31245-382d-465b-a415-fb3e2cf47f66.jpg?impolicy=fcrop&w=624&h=770&p=1&q=high) Photo by Bailey Swinford ## Top Chaffee Hotel Reviews ![Best Western Plus Sikeston](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37_y.jpg) ### Best Western Plus Sikeston 10/10 Excellent "Clean facility service was excellent." [](https://expedia.com/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![The Riverview](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg) ### The Riverview 10/10 Excellent "room was great, clean!!" [](https://expedia.com/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759_y.jpg) ### Hampton Inn Sikeston 10/10 Excellent "Very Clean room, friendly staff, breakfast in the morning. Will be staying again! " [](https://expedia.com/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![Quality Inn](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781_y.jpg) ### Quality Inn 10/10 Excellent "Well done " [](https://expedia.com/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) ![Courtyard by Marriott Cape Girardeau Downtown](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/ae49c8da_y.jpg) ### Courtyard by Marriott Cape Girardeau Downtown 10/10 Excellent "Such a pretty hotel and the room was amazing!" [](https://expedia.com/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) ![Drury Inn & Suites Cape Girardeau](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966_y.jpg) ### Drury Inn & Suites Cape Girardeau 10/10 Excellent "From our room, to food; this was one of the best experiences that we’ve had with hotel travel. The breakfast rivaled a restaurant, the evening snacks and beverages were above board. The staff was friendly, the rooms were clean. The location is fantastic with Outback right beside the hotel and shopping and conveniences very close. I would recommend this establishment, we will be staying here again" [](https://expedia.com/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ![Drury Inn & Suites Sikeston, MO](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg) ### Drury Inn & Suites Sikeston, MO 10/10 Excellent "Yes ever thing was great" [](https://expedia.com/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41_y.jpg) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau 10/10 Excellent "Yes .. staff was outstanding as was the cleanliness of the room" [](https://expedia.com/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ![Pear Tree Inn Cape Girardeau West](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg) ### Pear Tree Inn Cape Girardeau West 10/10 Excellent "Great " [](https://expedia.com/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ## More cheap stays in Chaffee ![Days Inn and Suites by Wyndham Sikeston](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Days Inn and Suites by Wyndham Sikeston 220 S Interstate Dr Sikeston MO $68 nightly $78 total Feb 16 - Feb 17 Total with taxes and fees 7.2/10 Good! (1,000 reviews) [](https://expedia.com/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) ![Pear Tree Inn Cape Girardeau West](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Pear Tree Inn Cape Girardeau West 103 Cape West Pkwy Cape Girardeau MO $72 nightly $81 total Feb 19 - Feb 20 Total with taxes and fees 9/10 Wonderful! (1,003 reviews) [](https://expedia.com/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Candlewood Suites Cape Girardeau by IHG](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/6afa6c85_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Candlewood Suites Cape Girardeau by IHG 485 S Mount Auburn Rd Cape Girardeau MO $80 nightly $96 total Feb 22 - Feb 23 Total with taxes and fees 8/10 Very Good! (895 reviews) [](https://expedia.com/Sikeston-Hotels-Candlewood-Suites-Cape-Girardeau.h3530303.Hotel-Information) ![Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG 3253 William Street Cape Girardeau MO $95 nightly $107 total Feb 22 - Feb 23 Total with taxes and fees 9.4/10 Exceptional! (1,000 reviews) [](https://expedia.com/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn Sikeston 1240 Commerce Drive Sikeston MO $95 nightly $108 total Feb 21 - Feb 22 Total with taxes and fees 8.8/10 Excellent! (478 reviews) [](https://expedia.com/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![Pear Tree Inn Cape Girardeau Near the Medical Center](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Pear Tree Inn Cape Girardeau Near the Medical Center 3248 William St Cape Girardeau MO [Get rates](https://expedia.com/Hotel-Search?startDate=2%2F28%2F2026&endDate=3%2F1%2F2026&selected=40113&PinnedHotelID=40113&HadPinnedHotel=true®ionId=553248634983269107) 8.8/10 Excellent! (1,000 reviews) [](https://expedia.com/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ## Hotels in Chaffee with star-rating ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 8 properties [](https://expedia.com/3Star-Chaffee-Hotels.s30-0-d553248634983269107.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 28 properties [](https://expedia.com/2Star-Chaffee-Hotels.s20-0-d553248634983269107.Travel-Guide-Filter-Hotels) ## Frequently asked questions ### Where is the best place to stay in Chaffee? ### What's the top vacation rental in Chaffee? ### If I need to cancel my hotel reservation in Chaffee, will I receive a refund? ### Where can I learn more about changing or cancelling my trip to Chaffee? ### How is it to stay in Chaffee? ### What is there to see in Chaffee? ### What's the seasonal weather like in Chaffee? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Dutchtown Hotels ](https://www.expedia.com/Dutchtown-Hotels.d3000349346.Travel-Guide-Hotels) - [Apartments in Dutchtown ](https://www.expedia.com/Dutchtown-Apartments.d3000349346-aaApartments.Travel-Guide-Accommodation) - [4 Star Hotels in Dutchtown ](https://www.expedia.com/4Star-Dutchtown-Hotels.s40-0-d3000349346.Travel-Guide-Filter-Hotels) - [Motels in Dutchtown ](https://www.expedia.com/Dutchtown-Motels.d3000349346-aaMotels.Travel-Guide-Accommodation) - [Hotels near Cape Girardeau Municipal ](https://www.expedia.com/Cape-Girardeau-Municipal-Airport-Hotels.0-aCGI-0.Travel-Guide-Filter-Hotels) - [Allenville Hotels ](https://www.expedia.com/Allenville-Hotels.d553248634983340903.Travel-Guide-Hotels) - [Flights from Dutchtown ](https://www.expedia.com/lp/flights/3000349346/flights-from-dutchtown) - [Flights from Cape Girardeau Municipal ](https://www.expedia.com/lp/airports/cgi/flights-from-cape-girardeau-municipal-airport) - [Flights from Nashville (BNA) to Cape Girardeau (CGI) ](https://www.expedia.com/lp/flights/bna/cgi/nashville-to-cape-girardeau) - 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