Photo by Abbie Moon

Find hotels in Chaffee, MO from $72

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Our top choices for Chaffee hotels

Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1004)
"Nice place for a stay at a reasonable price."
United States
Arthur
$70 nightly
The price is $79
Dec 28 - Dec 29
Total with taxes and fees
Pear Tree Inn Cape Girardeau Near the Medical Center

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1001)
"Great place and staff, very accommodating!"
United States
Megan
$90 nightly
The price is $102
Dec 28 - Dec 29
Total with taxes and fees
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1000)
"This our favorite place to stop for a good night sleep. "
United States
Eileen
$90 nightly
The price is $103
Dec 28 - Dec 29
Total with taxes and fees
Drury Inn & Suites Sikeston, MO

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very Good, (722)
"Room was good as usual. This is 4th stay over past 5 years. Only issue I had on this stay was the orange juice from breakfast options. "
United States
Todd
$55 nightly
The price is $63
Dec 25 - Dec 26
Total with taxes and fees
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Best Western Plus Sikeston

Best Western Plus Sikeston
2.5 star property
Sikeston
8.4 out of 10, Very Good, (1008)
"Great stay, everything was clean and comfortable. "
United States
Charles
$76 nightly
The price is $86
Dec 28 - Dec 29
Total with taxes and fees
Best Western Plus Sikeston

The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (476)
"The room was clean and the mattress was extremely comfortable "
United States
Stacy
$107 nightly
The price is $121
Dec 28 - Dec 29
Total with taxes and fees
The Riverview

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (450)
"clean room, comfy bedding, nice staff, convenient location "
United States
Alexa
$98 nightly
The price is $110
Jan 4 - Jan 5, 2026
Total with taxes and fees
Hampton Inn Sikeston

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (443)
"Staff was great. Hotel was clean. Great sleep. "
United States
Jeffrey
$100 nightly
The price is $113
Jan 10 - Jan 11, 2026
Total with taxes and fees
Holiday Inn Express & Suites Sikeston Southwest by IHG

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
2.5 star property
Sikeston
9.2 out of 10, Wonderful, (41)
"THE ROOM WAS SPOTLESS, CLEAN LOBBY, WARM AND LOT OF VARITY BREAKFAST, STAFF IS SO NICE."
United States
AHMAD
$101 nightly
The price is $114
Jan 1 - Jan 2, 2026
Total with taxes and fees
Fairfield Inn & Suites by Marriott Sikeston

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
8.8 out of 10, Excellent, (674)
"Great place "
United States
GUY
$84 nightly
The price is $91
Jan 7 - Jan 8, 2026
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1000)
"Very friendly staff and great breakfast"
United States
Ray
$90 nightly
The price is $102
Dec 28 - Dec 29
Total with taxes and fees
Drury Inn & Suites Cape Girardeau

Pear Tree Inn Sikeston

Pear Tree Inn Sikeston
2.5 star property
Sikeston
9.4 out of 10, Exceptional, (1001)
"Everything was clean, staff was friendly "
United States
Matthew
$75 nightly
The price is $86
Dec 28 - Dec 29
Total with taxes and fees
Pear Tree Inn Sikeston

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1010)
"Breakfast was great- staff was welcoming. Will stay there again."
United States
Laura
$83 nightly
The price is $88
Dec 28 - Dec 29
Total with taxes and fees
Drury Inn & Suites Jackson MO

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1000)
"Great stay"
United States
Heather
$70 nightly
The price is $79
Dec 28 - Dec 29
Total with taxes and fees
Pear Tree Inn Cape Girardeau West

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (468)
"The staff was very helpful and friendly. The rooms were modern and clean. The downtown location was perfect for us. "
United States
Deborah
$125 nightly
The price is $142
Jan 4 - Jan 5, 2026
Total with taxes and fees
Courtyard by Marriott Cape Girardeau Downtown

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (103)
"It was a nice stay"
United States
Douglas
$89 nightly
The price is $102
Jan 1 - Jan 2, 2026
Total with taxes and fees
Tru By Hilton Cape Girardeau

Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (785)
"Excellent stay"
United States
Christina
$102 nightly
The price is $115
Dec 30 - Dec 31
Total with taxes and fees
Hampton Inn Cape Girardeau I 55 East

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1000)
"We like to stay at this hotel on our way to New Orleans and on our return trip to Wisconsin. It is convenient, clean, breakfast options are excellent and the 8 pm cookie time is always a hit. Staff are also very friendly. "
United States
Brian
$91 nightly
The price is $103
Jan 4 - Jan 5, 2026
Total with taxes and fees
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (142)
"Nice hotel, clean and comfortable "
United States
Laura
$88 nightly
The price is $99
Jan 1 - Jan 2, 2026
Total with taxes and fees
Fairfield Inn & Suites by Marriott Cape Girardeau

Town House Inn

Town House Inn
2.5 star property
Jackson
7.6 out of 10, Good, (425)
"The staff member Tim was very friendly and nice. "
United States
Julie
$63 nightly
The price is $69
Jan 2 - Jan 3, 2026
Total with taxes and fees
Town House Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Chaffee

Venture to Isle Casino Cape Girardeau and Show Me Center—just two of the sights around Chaffee.

The Missouri State Tree - Dogwood
Photo by Abbie Moon
Open Photo by Abbie Moon

Top Chaffee Hotel Reviews

More cheap stays in Chaffee

Hotels in Chaffee with star-rating

Frequently asked questions

Where is the best place to stay in Chaffee?
Drury Plaza Hotel Cape Girardeau Conference Center, located 9.6 mi (15.5 km) from the heart of Chaffee, is a top choice for your stay based on our traveler data. Two other choices for your stay in the area are The Riverview and La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau. See all available top hotels, or vacation rentals in Chaffee.
What's the top vacation rental in Chaffee?
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool: This vacation home near Chaffee is located in a rural location and has an outdoor pool, a fireplace, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. It offers a balcony, a garden, and a selection of games so you can immerse yourself in your vacation. See all vacation rentals in Chaffee.
If I need to cancel my hotel reservation in Chaffee, will I receive a refund?
Yes! Most hotel reservations are refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, you might be able to still cancel and receive a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Chaffee.
Where can I learn more about changing or cancelling my trip to Chaffee?
For more details about picking new dates or cancelling your trip to Chaffee, head over to our customer service page.
How is it to stay in Chaffee?
Visitors are sure to enjoy all that Chaffee has to offer. There are 102 hotels and other accommodations in the surrounding area. Find out more about Chaffee.
What is there to see in Chaffee?
Places to visit in the wider area include Isle Casino Cape Girardeau, Show Me Center, and Cape Splash Family Aquatic Center. You'll also find Cape Girardeau Conservation Nature Center and Lazy L Safari Park in the area. Check out what more to see and do in Expedia's Chaffee guide.
What's the seasonal weather like in Chaffee?
The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 40°F. Average annual precipitation for Chaffee is 59 inches.

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