$298 Cheap American Airlines flights Charlotte (CLT) to Mexico City (MEX)

Use the "Price (lowest to highest)" filter on Expedia to find cheap American Airlines return flights from $555 from CLT to MEX. Affordable one-way fares from $298 are available too.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Landing the best American Airlines deals from CLT to MEX is typically all about timing. You can save 17% on international flights when you book 18 to 29 days before takeoff instead of four to five months ahead. To top it off, you can pocket 17% on average by buying your tickets on a Sunday compared to a Friday, which is usually the most expensive day to book.* It's smart to kick off your flight search about one month before your travel dates.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

The earliest American Airlines flight from CLT to MEX departs at 9:15AM UTC-5, landing at 12:45PM UTC-6. If you prefer to jet off later, the last American Airlines flight leaves CLT at 9:15AM UTC-5 and touches down at MEX at 12:45PM UTC-6. Flying earlier is often a smart choice as morning and mid-morning flights are less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.