
Popular airlines from Indianapolis Intl. Airport (IND) to San Diego Intl. Airport (SAN)
- Alaska Airlines
Alaska Airlines
- American Airlines
American Airlines
- United
United
- Delta
Delta
- Southwest Airlines
Southwest Airlines
- Frontier Airlines
Frontier Airlines
- Spirit Airlines
Spirit Airlines
- Plan, book, fly with confidence
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Cheap Flights from Indianapolis to San Diego (IND-SAN)
Prices were available within the past 7 days and start at $89 for one-way flights and $193 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.










Find the cheapest month to fly from Indianapolis (IND) to San Diego (SAN)
September is typically the cheapest month to fly
Graph displaying average flight prices per month
Alternative airports near San Diego
Prices were available within the past 7 days. Prices and availability are subject to change.
Origin airport | Indianapolis Intl. |
Destination airport | San Diego Intl. |
Airlines serving | Alaska Airlines, American Airlines, Delta, Frontier Airlines, Southwest Airlines, Spirit Airlines, Sun Country Airlines, United |
Roundtrip price | $192 |
Distance | 1778 mi |
Average flight time | 1 hour 10 mins |
Indianapolis to San Diego Flights
The cheapest times to fly from Indianapolis to San Diego
On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Indianapolis to San Diego are during the month of September. You can find some of the cheapest flights from Indianapolis to San Diego with Expedia's search tool and vast selection of airlines.
The best time to book a flight from Indianapolis to San Diego
Sunday is one of the best days to book for cheap flights from Indianapolis to San Diego: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.
How to find cheap round-trip tickets from Indianapolis to San Diego
Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Indianapolis to San Diego in 2025. You can also book with separate airlines for your outbound and return journeys, from $89 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.
Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Indianapolis to San Diego flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.
You could also save big by booking one of Expedia's vacation packages. Bundling together your Indianapolis to San Diego airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.
*Terms apply.
Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.
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Top Routes from Indianapolis
- Indianapolis to Newark Liberty Intl. Airport (IND - EWR)
- Indianapolis to Phoenix (IND - PHX)
- Indianapolis to Los Angeles (IND - LAX)
- Indianapolis to Miami (IND - MIA)
- Indianapolis to Tampa (IND - TPA)
- Indianapolis to Fort Lauderdale (IND - FLL)
- Indianapolis to New York (IND - LGA)
- Indianapolis to Boston (IND - BOS)
- Indianapolis to Denver (IND - DEN)
- Indianapolis to Seattle (IND - SEA)
- Indianapolis to New York (IND - JFK)
- Indianapolis to Dallas (IND - DAL)
Top Routes to San Diego
- Chicago to San Diego (ORD - SAN)
- Newark Liberty Intl. Airport to San Diego (EWR - SAN)
- Phoenix to San Diego (PHX - SAN)
- Portland to San Diego (PDX - SAN)
- New York to San Diego (LGA - SAN)
- Boston to San Diego (BOS - SAN)
- Honolulu to San Diego (HNL - SAN)
- Salt Lake City to San Diego (SLC - SAN)
- Denver to San Diego (DEN - SAN)
- Sacramento to San Diego (SMF - SAN)
- San Jose to San Diego (SJC - SAN)
- Washington to San Diego (IAD - SAN)
Top Routes from Indianapolis
- Spirit Airlines Indianapolis to Newark Liberty Intl. Airport
- American Airlines Indianapolis to Phoenix
- Alaska Airlines Indianapolis to Los Angeles
- American Airlines Indianapolis to Miami
- American Airlines Indianapolis to Tampa
- Delta Indianapolis to New York
- Spirit Airlines Indianapolis to Boston
- American Airlines Indianapolis to Denver
- Alaska Airlines Indianapolis to Seattle
- American Airlines Indianapolis to New York
Top Routes to San Diego
- Alaska Airlines Chicago to San Diego
- Alaska Airlines Newark Liberty Intl. Airport to San Diego
- Alaska Airlines Phoenix to San Diego
- Alaska Airlines Portland to San Diego
- Alaska Airlines Boston to San Diego
- Alaska Airlines Honolulu to San Diego
- Alaska Airlines Salt Lake City to San Diego
- Frontier Airlines Denver to San Diego
- Alaska Airlines Sacramento to San Diego
- Alaska Airlines San Jose to San Diego
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Carlsbad
Nearby Airports
- Purdue University Airport (LAF)
- Delaware County Airport (MIE)
- Butler County Regional Airport (HAO)
- Cincinnati - Northern Kentucky Intl. Airport (CVG)
- Fort Wayne Intl. Airport (FWA)
- University Of Illinois Urbana-Champaign Williard Airport (CMI)
- Cincinnati Municipal - Lunken Field Airport (LUK)
- Bowman Field Airport (LOU)
- Louisville Intl. Airport (SDF)
- James M. Cox Dayton Intl. Airport (DAY)
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