Title: Main Street Cultural District Tours - Book Now | Expedia.com [Main Street Cultural District Hotels](https://expedia.com/Main-Street-Cultural-District-Hotels.0-l6222268-0.Travel-Guide-Filter-Hotels)[Flights to Ames](https://expedia.com/Cheap-Flights-To-Ames.d6059972.Travel-Guide-Flights)[Car Rentals in Main Street Cultural District](https://expedia.com/Car-Rentals-In-Main-Street-Cultural-District.d6222268.Car-Rental-Guide)[Ames Vacation Packages](https://expedia.com/Ames.d6059972.Destination-Travel-Guides) # Main Street Cultural District Tours ![Main Street Cultural District showing a park and outdoor art](https://images.trvl-media.com/place/6222268/b2dd3a01-9a42-4bd7-a8c7-7034e4539395.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Main Street Cultural District](https://images.trvl-media.com/place/6222268/c69755d0-99ed-49fc-9193-5fb1d2b308ec.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Main Street Cultural District featuring signage](https://images.trvl-media.com/place/6222268/32b775c9-9e78-43d3-9707-d9d3e5d3b79a.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Main Street Cultural District](https://images.trvl-media.com/place/6222268/552c55b9-b4c3-4478-b037-f5af91d254eb.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Main Street Cultural District](https://images.trvl-media.com/place/6222268/a52f0c09-c735-40f8-87bc-968dba217df1.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Main Street Cultural District Activities [Ames Travel Guide](https://expedia.com/Ames.dx6059972) --- --- #### Eat and shop your way through the cultural center of Ames along a few popular streets notable for their history and bustling atmosphere. A visit to the Main Street Cultural District in Ames is a must for any visitor to the area. Try local delicacies from the family-owned restaurants and buy handcrafted goods from one of the many stores. Visit for a special event and see how the town celebrates. The Main Street Cultural District was created in 2009 after town leaders sought a way to give the area a gathering space and a common focus. It took 2 years to make this vision a reality. Enjoy the results of that hard work by adding this stop to your itinerary. When you first start your walk through the district, you will notice the smells of freshly cooked food wafting down the street. From pizza to hamburgers to Thai food, you’ll find restaurant options for everyone in your group. Sit down next to the window in a coffee shop to watch people go by. Purchase sandwiches from a local deli to eat as you wander. Shopping options are plentiful. Stop at a home furnishing store to outfit your house in eclectic textiles and handmade furniture. Go shopping for a new piece of jewelry at the silversmith’s store or buy a new pair of sandals from the many clothing and shoe stores. No matter what day you visit the area, there will likely be an event or class for you to join. Attend a lecture on computer basics, see a free concert on the weekends or take the kids to a movie night at the library. There are also seasonal activities for Christmas and the Fourth of July, as well as parades and trick-or-treating on Halloween. As the Main Street Cultural District is a collection of stores and restaurants, the individual businesses operate different hours throughout the year, but the streets themselves are always open for a stroll. Park in the bays along Main Street, which have meters for payment. ## Plan a trip to see Main Street Cultural District Price found within the past 48 hours. Click for updated prices. ![Qube Hotel](https://images.trvl-media.com/lodging/8000000/7810000/7803600/7803599/w1849h2927x0y0-cead3716_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Qube Hotel $503 per person Apr 30 - May 4 found 1 day ago Roundtrip non-stop flight included Los Angeles (QLA) to Des Moines (DSM) 8.4/10 Very Good! (733 reviews) Great staff! Enjoyed our stay. Reviewed on Dec 3, 2025 ![Hilton Des Moines Downtown](https://images.trvl-media.com/lodging/22000000/21330000/21321600/21321542/3d4c6021_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hilton Des Moines Downtown Downtown Des Moines $714 per person May 19 - May 23 found 22 hours ago Roundtrip non-stop flight included Boston (BOS) to Des Moines (DSM) 9/10 Wonderful! (999 reviews) This property is modern, super comfortable, restaurant bar - it can be a conference hotel or a family vacation. Parking, valet, layout is all so efficient, convenient and the staff are incredibly friendly and helpful. Online check in and room highlight guest safety and security. Nice lobby bar that can be as business-like or as casual as guests make it. Great stay. Reviewed on Mar 11, 2026 ![Hyatt Place West Des Moines Jordan Creek](https://images.trvl-media.com/lodging/17000000/16120000/16112600/16112546/018a0ab2_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hyatt Place West Des Moines Jordan Creek $605 per person May 19 - May 22 found 22 hours ago Roundtrip non-stop flight included Boston (BOS) to Des Moines (DSM) 9.2/10 Wonderful! (1,021 reviews) Quick Check in, Clean Room Reviewed on Mar 11, 2026 ### Popular places to visit ![Brunnier Art Museum showing a garden](https://images.trvl-media.com/place/6161472/63d2cbf6-0ddc-42b0-933e-481f2756a30b.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Brunnier Art Museum Be inspired by the decorative art exhibits at this university museum in central Iowa, where small-town America meets global culture. [](https://expedia.com/Brunnier-Art-Museum-Ames.d6161472.Vacation-Attraction) ![Reiman Gardens featuring a garden and wildflowers](https://images.trvl-media.com/place/6161484/097f1b5d-486d-4ba6-ae60-429d5a296ac9.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Reiman Gardens Walk the grounds of this manicured garden at Iowa State University, dedicated to educating current and future students as to how to grow food and plants. [](https://expedia.com/Reiman-Gardens-Ames.d6161484.Vacation-Attraction) ![Farm House Museum which includes a house](https://images.trvl-media.com/place/6161476/084d9038-54ef-4d07-8269-a7b3c04a189e.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Farm House Museum Discover the history of Iowa State University and the surrounding area of Ames at this museum and historic landmark right on campus. [](https://expedia.com/Farm-House-Museum-Ames.d6161476.Vacation-Attraction) ![Iowa State University which includes modern architecture](https://images.trvl-media.com/place/6105990/0f1f1774-eeaa-41e9-9054-fd5339e4acee.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Iowa State University Visit this public university to learn about its agricultural history and explore the many museums and cultural centers on the campus. [](https://expedia.com/Iowa-State-University-Ames.d6105990.Vacation-Attraction) ![Large park surrounding a lake located 3 miles north of Iowa State University campus.](https://images.trvl-media.com/place/6059972/089ec2d4-848c-493b-a070-f37f4552ac6c.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Ada Hayden Heritage Park Find out about the history of Ames with a stop at Ada Hayden Heritage Park. While in this family-friendly area, you can savor the top-notch restaurants. [](https://expedia.com/Ada-Hayden-Heritage-Park-Ames.d950929678989180928.Vacation-Attraction) #### Octagon Center for the Arts Enjoy an outing to Octagon Center for the Arts during your stay in Ames. In the area, you can attend a football game or basketball game. [](https://expedia.com/Octagon-Center-For-The-Arts-Ames.d6161482.Vacation-Attraction) --- ## Best Lodging Options Near Main Street Cultural District ## Check availability on hotels close to Main Street Cultural District [Tonight ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6222268&startDate=2026-03-16&endDate=2026-03-17)[Mar 16 - Mar 17](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6222268&startDate=2026-03-16&endDate=2026-03-17) [Tomorrow night ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6222268&startDate=2026-03-17&endDate=2026-03-18)[Mar 17 - Mar 18](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6222268&startDate=2026-03-17&endDate=2026-03-18) [This weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6222268&startDate=3%2F20%2F2026&endDate=3%2F22%2F2026)[Mar 20 - Mar 22](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6222268&startDate=3%2F20%2F2026&endDate=3%2F22%2F2026) [Next weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6222268&startDate=3%2F27%2F2026&endDate=3%2F29%2F2026)[Mar 27 - Mar 29](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6222268&startDate=3%2F27%2F2026&endDate=3%2F29%2F2026) ![Gateway Hotel and Conference Center at Iowa State University](https://images.trvl-media.com/lodging/1000000/710000/700100/700084/e19f459a_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Gateway Hotel and Conference Center at Iowa State University 2100 Green Hills Drive Ames IA [](https://expedia.com/Ames-Hotels-Gateway-Hotel-And-Conference-Center.h700084.Hotel-Information) ![Comfort Inn and Suites Ames near ISU Campus](https://images.trvl-media.com/lodging/33000000/32530000/32524100/32524052/8a37ae20_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Comfort Inn and Suites Ames near ISU Campus 603 South 16th Street Ames IA [](https://expedia.com/Ames-Hotels-Comfort-Inn-And-Suites-Ames-Near-ISU-Campus.h32524052.Hotel-Information) ![GrandStay Hotel & Suites](https://images.trvl-media.com/lodging/2000000/1290000/1287600/1287582/b4e69589_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### GrandStay Hotel & Suites 1606 S Kellogg Ave Ames IA [](https://expedia.com/Ames-Hotels-GrandStay-Hotel-Suites.h1287582.Hotel-Information) ![Courtyard by Marriott Ames](https://images.trvl-media.com/lodging/54000000/53900000/53896300/53896211/6998c56f_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Courtyard by Marriott Ames 311 SOUTH 17TH STREET Ames IA [](https://expedia.com/Ames-Hotels-Courtyard-BY-Marriott-Ames.h53896211.Hotel-Information) ![Best Western Plus University Park Inn & Suites](https://images.trvl-media.com/lodging/1000000/60000/51200/51136/9d150149_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Best Western Plus University Park Inn & Suites 2500 University Blvd. Ames IA [](https://expedia.com/Ames-Hotels-Best-Western-Plus-University-Park-Inn-Suites.h51136.Hotel-Information) ![SpringHill Suites by Marriott Ames](https://images.trvl-media.com/lodging/60000000/59860000/59855200/59855184/25509de7_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### SpringHill Suites by Marriott Ames 1810 SE 16TH STREET Ames IA [](https://expedia.com/Ames-Hotels-SpringHill-Suites-By-Marriott-Ames.h59855184.Hotel-Information) ![AmericInn by Wyndham Ames](https://images.trvl-media.com/lodging/1000000/570000/561200/561156/25910fe8_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### AmericInn by Wyndham Ames 2507 SE 16th St. Ames IA [](https://expedia.com/Ames-Hotels-AmericInn-By-Wyndham-Ames.h561156.Hotel-Information) ![Home2 Suites By Hilton Ames](https://images.trvl-media.com/lodging/110000000/109390000/109388300/109388207/w5752h3837x5y3-3518054c_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Home2 Suites By Hilton Ames 2125 Isaac Newton Dr Ames IA [](https://expedia.com/Ames-Hotels-Home2-Suites-By-Hilton-Ames.h109388207.Hotel-Information) ![Country Inn & Suites by Radisson, Ames, IA](https://images.trvl-media.com/lodging/1000000/560000/554100/554070/66ecaafe_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Country Inn & Suites by Radisson, Ames, IA 2605 Se 16th St Ames IA [](https://expedia.com/Ames-Hotels-Country-Inn-Suites-By-Radisson.h554070.Hotel-Information) [See all 754 properties in Main Street Cultural District](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package®ionId=6222268) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. 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