Find luxury hotels in Florence, SC

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Top Florence Luxury Hotels

The Mantissa Hotel

3.0 star property
9.2 out of 10, Wonderful, (262)
"Excellent stay"
$162 nightly
The price is $181
Oct 12 - Oct 13
Total with taxes and fees
The Mantissa Hotel

Days Inn by Wyndham Dillon

2.0 star property
5.4 out of 10, (838)
"The staff were geeat. The motel room was not so great!!!"
$50 nightly
The price is $56
Oct 15 - Oct 16
Total with taxes and fees
Days Inn by Wyndham Dillon

Hotel Florence, Tapestry Collection by Hilton

3.0 star property
8.8 out of 10, Excellent, (586)
"Staff front desk was very pleasant. Wendy at front desk was awesome, very polite , pleasant. The Manager over the kitchen in Victors restaurant is great . She was very attentive and polite. Most of the staff we saw like the hostesses for the onsite restaurant was great. Rooms clean and nice bathrooms clean shower may just need small cleaning around board area but very clean "
$135 nightly
The price is $151
Oct 12 - Oct 13
Total with taxes and fees
Hotel Florence, Tapestry Collection by Hilton

Days Inn by Wyndham Florence/I-95 North

2.0 star property
6.8 out of 10, (1003)
"Clean room Nice staff Good area Plenty of food places to eat Air conditioning worked great Nice place"
$64 nightly
The price is $71
Nov 1 - Nov 2
Total with taxes and fees
Days Inn by Wyndham Florence/I-95 North

Baymont Inn & Suites Florence by Wyndham

2.5 star property
5.6 out of 10, (1000)
"good to stay "
Baymont Inn & Suites Florence by Wyndham

Clarion Inn & Suites

2.5 star property
4.4 out of 10, (288)
"It appears the property is under new management and possible being updated. The room was very inexpensive and the staff charge a deposit refundable typically 3-5 business days almost as much as room cost. My room was prepaid before I arrived. "
$54 nightly
The price is $61
Oct 8 - Oct 9
Total with taxes and fees
Clarion Inn & Suites

Red Roof Inn Florence - Civic Center

2.0 star property
6.8 out of 10, (1002)
"Close to favorite restaurants."
$56 nightly
The price is $63
Oct 12 - Oct 13
Total with taxes and fees
Red Roof Inn Florence - Civic Center

Days Inn by Wyndham Florence Near Civic Center

2.5 star property
6.8 out of 10, (1002)
"Overall the check in time & process online was easy and fast."
$66 nightly
The price is $74
Oct 7 - Oct 8
Total with taxes and fees
Days Inn by Wyndham Florence Near Civic Center

Quality Inn & Suites

2.5 star property
7.2 out of 10, Good, (742)
"Excellent place for an overnight stay!"
$66 nightly
The price is $74
Oct 15 - Oct 16
Total with taxes and fees
Quality Inn & Suites

Quality Inn & Suites Florence Civic Center

2.5 star property
7.8 out of 10, Good, (1244)
"The staff makes this place my go to for overnight stays in Florence. The hotel is clean and freshly renovated. You can’t beat the price/value of this hotel. "
$85 nightly
The price is $95
Oct 7 - Oct 8
Total with taxes and fees
Quality Inn & Suites Florence Civic Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Florence

Find out more about Florence

Florenceand its attractions for luxury travelers

Florence, South Carolina, offers a blend of Southern charm and luxurious experiences perfect for travelers. Begin your exploration at the Florence Museum, where you can admire a diverse collection of Southern art and historical artifacts in a beautifully designed space. For a taste of local culture, the Magnolia Mall provides a shopping experience featuring upscale retailers and boutiques, ideal for indulging in some retail therapy. Nature lovers will appreciate a stroll through the serene gardens at the Florence County Museum, where the exhibits are complemented by picturesque outdoor spaces. If you're seeking adventure, the nearby Lynches River County Park offers kayaking and hiking opportunities that allow you to connect with the natural beauty of the region. For accommodations, the area around the historic downtown is particularly appealing, with luxury hotels that provide a blend of modern comfort and Southern hospitality. Enjoy spacious suites, gourmet dining options, and attentive service, ensuring a pampered stay as you explore Florence's attractions.

Top Florence Hotel Reviews

Frequently asked questions

Are you searching for the perfect hotel for your luxury holiday in Florence?
Expedia can help you get a flight to Florence, SC (FLO-Florence Regional) airport, and then you can select from a variety of places to stay that will deliver the luxury you seek. Amenities are an important consideration when you plan a vacation, so we make it easy to find what you'd like to make your stay special. If you want a posh hotel that has a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Florence offers. During your visit, you might want to enjoy the shopping which Florence is known for.
When can I expect good weather in Florence?
Planning for the weather is a good way to make your trip to Florence relaxing and enjoyable, especially when you're splurging. The hottest months are usually July and August with an average temp of 78°F, while the coldest months are January and February with an average of 50°F. Average annual precipitation for Florence is 54 inches.
What's there to see and do in Florence?
Take in the sights and attractions that Florence offers with a visit to Florence Museum, Florence National Cemetery, and Magnolia Mall. If you have extra time while you're in the area, you might want to stop by Florence Veterans Park and Florence Civic Center.
How can I get around Florence?
It's easier to get around town in style when you know your options. If you want to venture outside of the area, hop aboard a train at Florence Station.

Explore a world of travel with Expedia

Explore a world of travel with Expedia