Title: Florence Vacation Rentals from $188: Search Short-Term Rentals | Expedia.com [Florence Travel Guide](https://expedia.com/Florence.dx1221)[Hotels in Florence](https://expedia.com/Florence-Hotels.d1221.Travel-Guide-Hotels)[Flights to Florence](https://expedia.com/Cheap-Flights-To-Florence.d1221.Travel-Guide-Flights)[Things to do in Florence](https://expedia.com/Things-To-Do-In-Florence.d1221.Travel-Guide-Activities)[Car Rentals in Florence](https://expedia.com/Car-Rentals-In-Florence.d1221.Car-Rental-Guide)[Florence Vacation Packages](https://expedia.com/Florence.d1221.Destination-Travel-Guides) ![Lodging Image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_bundle_and_save.svg) ### Bundle & Save Get more, spend less whenever you see Bundle & Save deals - ![](https://a.travel-assets.com/travel-assets-manager/pictograms-expedia/light__onekey.svg) ### OneKeyCash Earn OneKeyCash on all your eligible bookings - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_ftc.svg) ### Upfront pricing We are not like the others - we include taxes and fees ## Check prices for these dates In two weeks [Mar 27 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=1221&startDate=2026-03-27&endDate=2026-03-29&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [May 8 - May 10](https://www.expedia.com/Hotel-Search?regionId=1221&startDate=2026-05-08&endDate=2026-05-10&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [Jun 5 - Jun 7](https://www.expedia.com/Hotel-Search?regionId=1221&startDate=2026-06-05&endDate=2026-06-07&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [Jul 3 - Jul 5](https://www.expedia.com/Hotel-Search?regionId=1221&startDate=2026-07-03&endDate=2026-07-05&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Florence vacation rentals ![Villa (6 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93210000/93207300/93207276/7a95723f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Villa (6 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93210000/93207300/93207276/53cb37e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Villa (6 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93210000/93207300/93207276/3c501c81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Villa (6 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93210000/93207300/93207276/d0e72394.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Family Laurinburg Home w/ Private Yard & BBQ [](https://www.expedia.com/Laurinburg-Hotels-Family-Laurinburg-Home-W-Private-Yard-BBQ.h93207276.Hotel-Information) Laurinburg 10/10 Exceptional (1 review) "This home is so beautiful. I will definitely be staying here again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gail $742 nightly $836 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Laurinburg-Hotels-Family-Laurinburg-Home-W-Private-Yard-BBQ.h93207276.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-29&endDate=2026-03-30®ionId=1221&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=VR_SPRING_PROMO_1221) ## Find vacation rentals that suit your style Private vacation homes [](https://www.expedia.com/Hotel-Search?destination=Florence%2C+South+Carolina%2C+United+States+of+America®ionId=1221&latLong=34.197201%2C-79.768181&adults=2&startDate=2026-06-13&d1=2026-06-13&endDate=2026-06-16&d2=2026-06-16&lodging=VACATION_HOME) Cottages [](https://www.expedia.com/Hotel-Search?destination=Florence%2C+South+Carolina%2C+United+States+of+America®ionId=1221&latLong=34.197201%2C-79.768181&adults=2&startDate=2026-06-13&d1=2026-06-13&endDate=2026-06-16&d2=2026-06-16&lodging=COTTAGE) Apartments [](https://www.expedia.com/Hotel-Search?destination=Florence%2C+South+Carolina%2C+United+States+of+America®ionId=1221&latLong=34.197201%2C-79.768181&adults=2&startDate=2026-06-13&d1=2026-06-13&endDate=2026-06-16&d2=2026-06-16&lodging=APARTMENT) Cabins [](https://www.expedia.com/Hotel-Search?destination=Florence%2C+South+Carolina%2C+United+States+of+America®ionId=1221&latLong=34.197201%2C-79.768181&adults=2&startDate=2026-06-13&d1=2026-06-13&endDate=2026-06-16&d2=2026-06-16&lodging=CABIN) Condos [](https://www.expedia.com/Hotel-Search?destination=Florence%2C+South+Carolina%2C+United+States+of+America®ionId=1221&latLong=34.197201%2C-79.768181&adults=2&startDate=2026-06-13&d1=2026-06-13&endDate=2026-06-16&d2=2026-06-16&lodging=CONDO) Villas [](https://www.expedia.com/Hotel-Search?destination=Florence%2C+South+Carolina%2C+United+States+of+America®ionId=1221&latLong=34.197201%2C-79.768181&adults=2&startDate=2026-06-13&d1=2026-06-13&endDate=2026-06-16&d2=2026-06-16&lodging=VILLA) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FFlorence-Vacation-Rentals.d1221.Travel-Guide-VacationRentals)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FFlorence-Vacation-Rentals.d1221.Travel-Guide-VacationRentals) ## Top Florence Hotel Reviews ![Comfort Inn & Suites Florence Center Area](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/64840011_y.jpg) ### Comfort Inn & Suites Florence Center Area 10/10 Excellent "The rooms, lobby, and parking area were all clean and comfortable." [](https://expedia.com/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![Hyatt Place Florence Downtown](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c8bc9166_y.jpg) ### Hyatt Place Florence Downtown 4/10 Poor "We were there for 5 nights and no one knocked on our door to clean our room. We had to ask for clean towels and empty our own garbage cans. The service was terrible." [](https://expedia.com/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information) ![Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG](https://images.trvl-media.com/lodging/2000000/1510000/1509700/1509674/9c0353ec_y.jpg) ### Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG 10/10 Excellent "Clean room, easy parking, great breakfast" [](https://expedia.com/Florence-Hotels-Holiday-Inn-Ex-Hotel-Suites-Florence-I-95-I-20-Civic-Ctr.h1509674.Hotel-Information) ![SpringHill Suites by Marriott Florence](https://images.trvl-media.com/lodging/1000000/980000/975000/974962/bad3cc5c_y.jpg) ### SpringHill Suites by Marriott Florence 6/10 Okay "We’ve stayed here several times in the heat 3 years. This least stay the breakfast was disappointing. Grey pork sausage and runny eggs were the hot bar foods. I usually look forward to the hot foods because my gluten and corn allergies rule most other items. The hot oatmeal and toppings were very good. " [](https://expedia.com/Florence-Hotels-SpringHill-Suites-By-Marriott-Florence.h974962.Hotel-Information) ![Quality Inn & Suites Florence Civic Center](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/8dae8685_y.jpg) ### Quality Inn & Suites Florence Civic Center 10/10 Excellent "The property was renovated and CLEAN. It was the Best stay ever. The staff was friendly. I remembered them as I've stayed at the property prior. I was comfortable and enjoyed my stay. " [](https://expedia.com/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) ![Tru by Hilton Florence I-95](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/a8854f5d_y.jpg) ### Tru by Hilton Florence I-95 10/10 Excellent "The room was comfortable but just a bit compact. Not complaining just giving an assessment. The tv is n at least a 55 inch flat screen mounted on the wall at a good height above the desk.The bathroom was spacious enough and with a walk-in shower and plenty of lighting. We enjoyed our stay and would highly recommend this hotel." [](https://expedia.com/Florence-Hotels-Tru-By-Hilton-Florence-I-95.h27041849.Hotel-Information) ![TownePlace Suites by Marriott Florence](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/cd925f1d_y.jpg) ### TownePlace Suites by Marriott Florence 8/10 Good "Very clean room, bathroom.. Only things that weren’t excellent were the towels were fairly rough and bedspread felt short for bed, didn’t come up to chin even. Otherwise was an excellent stay and would stay again. Check in Hannah was great!" [](https://expedia.com/Florence-Hotels-TownePlace-Suites-By-Marriott-Florence.h10620701.Hotel-Information) ![Park Inn by Radisson Florence, SC](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/e4f3361f_y.jpg) ### Park Inn by Radisson Florence, SC 6/10 Okay "The room had a peculiar smell. The water pressure was very low in the shower. And the shower floor needed a good scrubbing with bleach. " [](https://expedia.com/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) ![Howard Johnson by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1_y.jpg) ### Howard Johnson by Wyndham Florence 8/10 Good "Staff very pleasant " [](https://expedia.com/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ## Find out more about Florence **Everything you need to know about Florence vacation rentals** Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Florence vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on. There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Florence vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. **Florence vacation rentals: An excellent choice for every season** Whenever you want to travel, a warm welcome awaits you in Florence. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Florence in high season. Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $188 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals! **How to find incredible deals on Florence rentals** At Expedia, we put the best Florence vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. To find some top Florence rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Florence vacation. If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Florence. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. ## Explore a world of travel with Expedia - Trending destinations on Expedia.com - All accommodation types in Florence ### Trending destinations on Expedia.com - [Destin Vacation Rentals ](https://www.expedia.com/Destin-Vacation-Rentals.d6906.Travel-Guide-VacationRentals) - [Panama City Vacation Rentals ](https://www.expedia.com/Panama-City-Beach-Vacation-Rentals.d8021.Travel-Guide-VacationRentals) - [Hilton Head Vacation Rentals ](https://www.expedia.com/Hilton-Head-Island-Vacation-Rentals.d601684.Travel-Guide-VacationRentals) - [Gulf Shores Vacation Rentals ](https://www.expedia.com/Gulf-Shores-Vacation-Rentals.d603078.Travel-Guide-VacationRentals) - [Key West Vacation Rentals ](https://www.expedia.com/Key-West-Vacation-Rentals.d1187.Travel-Guide-VacationRentals) - [Gatlinburg Vacation Rentals ](https://www.expedia.com/Gatlinburg-Vacation-Rentals.d7474.Travel-Guide-VacationRentals) - [Maui Vacation Rentals ](https://www.expedia.com/Maui-Vacation-Rentals.d180073.Travel-Guide-VacationRentals) - [Orlando Vacation Rentals ](https://www.expedia.com/Orlando-Vacation-Rentals.d178294.Travel-Guide-VacationRentals) - [Myrtle Beach Vacation Rentals ](https://www.expedia.com/Myrtle-Beach-Vacation-Rentals.d601685.Travel-Guide-VacationRentals) - [Orange Beach Vacation Rentals ](https://www.expedia.com/Orange-Beach-Vacation-Rentals.d9136.Travel-Guide-VacationRentals) - [Pigeon Forge Vacation Rentals ](https://www.expedia.com/Pigeon-Forge-Vacation-Rentals.d8264.Travel-Guide-VacationRentals) - [Ocean City Vacation Rentals ](https://www.expedia.com/Ocean-City-Vacation-Rentals.d9151.Travel-Guide-VacationRentals) - [Outer Banks Vacation Rentals ](https://www.expedia.com/Outer-Banks-Vacation-Rentals.d602135.Travel-Guide-VacationRentals) - [San Diego Vacation Rentals ](https://www.expedia.com/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals) - [Siesta Key Vacation Rentals ](https://www.expedia.com/Siesta-Key-Vacation-Rentals.d6881.Travel-Guide-VacationRentals) - [Galveston Vacation Rentals ](https://www.expedia.com/Galveston-Vacation-Rentals.d1341.Travel-Guide-VacationRentals) - [Clearwater Beach Vacation Rentals ](https://www.expedia.com/Clearwater-Beach-Vacation-Rentals.d10759.Travel-Guide-VacationRentals) - [Palm Springs Vacation Rentals ](https://www.expedia.com/Palm-Springs-Vacation-Rentals.d180676.Travel-Guide-VacationRentals) - [Florida Keys Vacation Rentals ](https://www.expedia.com/Florida-Keys-Vacation-Rentals.d6023765.Travel-Guide-VacationRentals) - [Lake Tahoe Vacation Rentals ](https://www.expedia.com/South-Lake-Tahoe-Vacation-Rentals.d10150.Travel-Guide-VacationRentals) - [Lake of the Ozarks Vacation Rentals ](https://www.expedia.com/Lake-Ozark-Vacation-Rentals.d177772.Travel-Guide-VacationRentals) - [Florida Vacation Rentals ](https://www.expedia.com/Destinations-In-Florida.d211.Vacation-Rental-Destinations) - [Hawaii Vacation Rentals ](https://www.expedia.com/Destinations-In-Hawaii.d213.Vacation-Rental-Destinations) - [Michigan Vacation Rentals ](https://www.expedia.com/Destinations-In-Michigan.d224.Vacation-Rental-Destinations) - [Vacation Homes in Florence ](https://expedia.com/Florence-Private-Vacation-Homes.d1221-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Motels in Florence ](https://expedia.com/Florence-Motels.d1221-aaMotels.Travel-Guide-Accommodation) - [Cottages in Florence ](https://expedia.com/Florence-Cottages.d1221-aaCottages.Travel-Guide-Accommodation) - [Apartments in Florence ](https://expedia.com/Florence-Apartments.d1221-aaApartments.Travel-Guide-Accommodation) - [Condo Rentals in Florence ](https://expedia.com/Florence-Condos.d1221-aaCondos.Travel-Guide-Accommodation) - [Farmstay in Florence ](https://expedia.com/Florence-Agritourism.d1221-aaAgritourism.Travel-Guide-Accommodation) - [Guest Houses in Florence ](https://expedia.com/Florence-Guest-Houses.d1221-aaGuestHouses.Travel-Guide-Accommodation) - [B&B in Florence ](https://expedia.com/Florence-Bed-And-Breakfast.d1221-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cabin Rentals in Florence ](https://expedia.com/Florence-Cabins.d1221-aaCabins.Travel-Guide-Accommodation) - [Villas in Florence ](https://expedia.com/Florence-Villas.d1221-aaVillas.Travel-Guide-Accommodation) - [RV Parks in Florence ](https://expedia.com/Florence-RV-Parks.d1221-aaRVParks.Travel-Guide-Accommodation) ## Frequently asked questions ### Can I find vacation rentals in Florence? ### What are some of the best vacation rentals in Florence? ### How many vacation rentals will I find in Florence? ### What can I see and do in Florence? ### What are vacation rentals like in Florence? ### Expedia's Latest Trends Hotels - [Charleston Oceanfront Hotels](https://expedia.com/Charleston-Hotels-Oceanfront-Hotels.0-0-d179997-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - [Beaufort Hotels](https://expedia.com/Beaufort-Hotels.d6057941.Travel-Guide-Hotels) - [Mount Pleasant Hotels](https://expedia.com/Mount-Pleasant-Hotels.d8675.Travel-Guide-Hotels) - [Charleston Cheap Hotels](https://expedia.com/Charleston-Hotels-Cheap-Hotels.0-0-d179997-tCheapHotels.Travel-Guide-Filter-Hotels) - [Summerville Hotels](https://expedia.com/Summerville-Hotels.d6992.Travel-Guide-Hotels) - [Myrtle Beach Hotels](https://expedia.com/Myrtle-Beach-Hotels.d601685.Travel-Guide-Hotels) - [Myrtle Beach All-inclusive Resorts](https://expedia.com/Myrtle-Beach-Hotels-All-Inclusive-Hotel.0-0-d601685-tAllinclusiveHotel.Travel-Guide-Filter-Hotels) - [North Myrtle Beach Hotels](https://expedia.com/North-Myrtle-Beach-Hotels.d8929.Travel-Guide-Hotels) - [Greenville Hotels](https://expedia.com/Greenville-Hotels.d1388.Travel-Guide-Hotels) - [Myrtle Beach Oceanfront Hotels](https://expedia.com/Myrtle-Beach-Hotels-Oceanfront-Hotels.0-0-d601685-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - [Hilton Head Island Hotels](https://expedia.com/Hilton-Head-Island-Hotels.d601684.Travel-Guide-Hotels) - [Hilton Head Island Oceanfront Hotels](https://expedia.com/Hilton-Head-Island-Hotels-Oceanfront-Hotels.0-0-d601684-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - [Columbia Hotels](https://expedia.com/Columbia-Hotels.d764.Travel-Guide-Hotels) - [Myrtle Beach Cheap Hotels](https://expedia.com/Myrtle-Beach-Hotels-Cheap-Hotels.0-0-d601685-tCheapHotels.Travel-Guide-Filter-Hotels) - [North Myrtle Beach Oceanfront Hotels](https://expedia.com/North-Myrtle-Beach-Hotels-Oceanfront-Hotels.0-0-d8929-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - [Charleston Hotels](https://expedia.com/Charleston-Hotels.d179997.Travel-Guide-Hotels) - [Myrtle Beach Pet-friendly Hotels](https://expedia.com/Myrtle-Beach-Hotels-Pet-Friendly-Hotel.0-0-d601685-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Folly Beach Oceanfront Hotels](https://expedia.com/Folly-Beach-Hotels-Oceanfront-Hotels.0-0-d7217-tOceanfrontHotels.Travel-Guide-Filter-Hotels) Flights - [Flights to Columbia](https://expedia.com/Cheap-Flights-To-Columbia.d764.Travel-Guide-Flights) - [Flights to Charleston](https://expedia.com/Cheap-Flights-To-Charleston.d179997.Travel-Guide-Flights) - [Flights to Hilton Head Island](https://expedia.com/Cheap-Flights-To-Hilton-Head-Island.d601684.Travel-Guide-Flights) - [Flights to Myrtle Beach](https://expedia.com/Cheap-Flights-To-Myrtle-Beach.d601685.Travel-Guide-Flights) Cars - [Car rentals in Columbia](https://expedia.com/Car-Rentals-In-Columbia.d764.Car-Rental-Guide) - [Car rentals in Charleston](https://expedia.com/Car-Rentals-In-Charleston.d179997.Car-Rental-Guide) - [Car rentals in Myrtle Beach](https://expedia.com/Car-Rentals-In-Myrtle-Beach.d601685.Car-Rental-Guide) - [Car rentals in Greenville](https://expedia.com/Car-Rentals-In-Greenville.d1388.Car-Rental-Guide) Cruises - [Cruises from Charleston](https://expedia.com/Cruises-from-Charleston.d179997.Cruise-Departure-Port) Activities - [Things to do in Myrtle Beach](https://expedia.com/Things-To-Do-In-Myrtle-Beach.d601685.Travel-Guide-Activities) Packages - [Trip to Myrtle Beach](https://expedia.com/Myrtle-Beach.d601685.Destination-Travel-Guides) Vacation Rentals - [Rentals in Myrtle Beach](https://expedia.com/Myrtle-Beach-Vacation-Rentals.d601685.Travel-Guide-VacationRentals) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app