Title: Isernia Vacation Rentals from $68: Search Short-Term Rentals | Expedia.com

[Isernia Travel Guide](https://expedia.com/Isernia.dx6123603)[Hotels in Isernia](https://expedia.com/Isernia-Hotels.d6123603.Travel-Guide-Hotels)[Flights to Isernia](https://expedia.com/Cheap-Flights-To-Isernia.d6123603.Travel-Guide-Flights)[Car Rentals in Isernia](https://expedia.com/Car-Rentals-In-Isernia.d6123603.Car-Rental-Guide)[Isernia Vacation Packages](https://expedia.com/Isernia.d6123603.Destination-Travel-Guides)

![Pesche - Panoramica dai vicoli](https://images.trvl-media.com/place/6123603/46b9e970-ecd0-4568-9acd-668fde8713e6.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/6123603/46b9e970-ecd0-4568-9acd-668fde8713e6.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

In two weeks

[Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=6123603&startDate=2026-03-13&endDate=2026-03-15&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[Apr 24 - Apr 26](https://www.expedia.com/Hotel-Search?regionId=6123603&startDate=2026-04-24&endDate=2026-04-26&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[May 22 - May 24](https://www.expedia.com/Hotel-Search?regionId=6123603&startDate=2026-05-22&endDate=2026-05-24&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jun 19 - Jun 21](https://www.expedia.com/Hotel-Search?regionId=6123603&startDate=2026-06-19&endDate=2026-06-21&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Isernia vacation rentals

![Terrace/patio](https://images.trvl-media.com/lodging/110000000/109120000/109110900/109110821/9a972550.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/110000000/109120000/109110900/109110821/9786bef7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/110000000/109120000/109110900/109110821/eedeebcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/110000000/109120000/109110900/109110821/50f49837.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Alley

[](https://www.expedia.com/Isernia-Hotels-The-Alley.h109110821.Hotel-Information)

Isernia

$201 nightly

$201 total

Mar 2 - Mar 3

Total with taxes and fees

[](https://www.expedia.com/Isernia-Hotels-The-Alley.h109110821.Hotel-Information)

![Interior entrance](https://images.trvl-media.com/lodging/4000000/3030000/3025000/3024967/bffbbdc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hallway](https://images.trvl-media.com/lodging/4000000/3030000/3025000/3024967/37898747.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/4000000/3030000/3025000/3024967/4c63a04f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hallway](https://images.trvl-media.com/lodging/4000000/3030000/3025000/3024967/2f77c2a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Dimora del Prete di Belmonte - Bed & Breakfast

[](https://www.expedia.com/Venafro-Hotels-Dimora-Del-Prete-Di-Belmonte-Bed-Breakfast.h3024967.Hotel-Information)

Venafro

9.6/10

Exceptional

(34 reviews)

"Amazing old palazzo in a beautiful rustic medieval hilltop village. The owner, Dorothy is very warm and welcoming. Breakfast was delicious. I would definitely recommend this bed and breakfast! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Shelbie

$115 nightly

$127 total

Mar 13 - Mar 14

Total with taxes and fees

[](https://www.expedia.com/Venafro-Hotels-Dimora-Del-Prete-Di-Belmonte-Bed-Breakfast.h3024967.Hotel-Information)

![1 bedroom, free WiFi](https://images.trvl-media.com/lodging/45000000/44970000/44963900/44963819/90-75a69e1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/45000000/44970000/44963900/44963819/90-6bc083a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/45000000/44970000/44963900/44963819/90-bc707c6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/45000000/44970000/44963900/44963819/180-e69328c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Colonial house Ciociara

[](https://www.expedia.com/Cervaro-Hotels-Colonial-House-Ciociara.h44963819.Hotel-Information)

Cervaro

$54 nightly

$68 total

Mar 19 - Mar 20

Total with taxes and fees

[](https://www.expedia.com/Cervaro-Hotels-Colonial-House-Ciociara.h44963819.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/97000000/96500000/96495400/96495325/876d0795.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96500000/96495400/96495325/099b4d09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/97000000/96500000/96495400/96495325/a0e6e91b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, books](https://images.trvl-media.com/lodging/97000000/96500000/96495400/96495325/cd4f4680.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Ampio Appartamento Moderno

[](https://www.expedia.com/Longano-Hotels-Vrbo-Property.h96495325.Hotel-Information)

Molise

8.8/10

Excellent

(3 reviews)

"Town was pleasant, the owner Luca was fantastic. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

frank n.

$80 nightly

$80 total

Mar 1 - Mar 2

Total with taxes and fees

[](https://www.expedia.com/Longano-Hotels-Vrbo-Property.h96495325.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/114000000/113640000/113636200/113636139/e73194e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV, books, stereo](https://images.trvl-media.com/lodging/114000000/113640000/113636200/113636139/c4535c43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV, books, stereo](https://images.trvl-media.com/lodging/114000000/113640000/113636200/113636139/d6d4d4f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/114000000/113640000/113636200/113636139/86f67e97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### BELVEDERE - Bed & Breakfast - Holiday Home

[](https://www.expedia.com/Pozzilli-Hotels-Vrbo-Property.h113636139.Hotel-Information)

Pozzilli

$78 nightly

$78 total

Mar 2 - Mar 3

Total with taxes and fees

[](https://www.expedia.com/Pozzilli-Hotels-Vrbo-Property.h113636139.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/36000000/35840000/35839300/35839211/00c35391.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/36000000/35840000/35839300/35839211/8a09b1d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/36000000/35840000/35839300/35839211/w1295h750x0y0-8823051c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/36000000/35840000/35839300/35839211/ab7d84ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### A Casa Di Tina, beautiful and new apartment in the heart of Cassino

[](https://www.expedia.com/Cassino-Hotels-A-Casa-Di-Tina.h35839211.Hotel-Information)

Cassino

9.8/10

Exceptional

(12 reviews)

"Very welcoming and a good place as home away from home."

![Italy](https://a.travel-assets.com/egds/marks/flags/it.svg)

Ebenezer

$136 nightly

$136 total

Mar 1 - Mar 2

Total with taxes and fees

[](https://www.expedia.com/Cassino-Hotels-A-Casa-Di-Tina.h35839211.Hotel-Information)

![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/115000000/114270000/114266500/114266475/65b38fb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/115000000/114270000/114266500/114266475/ca78f000.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/115000000/114270000/114266500/114266475/3de1fe10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/115000000/114270000/114266500/114266475/58c5c387.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cassino-two-room apartment-park rondo

[](https://www.expedia.com/Cassino-Hotels-Cassino-Two-Room-Apartment-Park-Rondo.h114266475.Hotel-Information)

Cassino

[](https://www.expedia.com/Cassino-Hotels-Cassino-Two-Room-Apartment-Park-Rondo.h114266475.Hotel-Information)

![Apartment, Balcony, Mountain View | Terrace/patio](https://images.trvl-media.com/lodging/124000000/123380000/123379900/123379847/327fea30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, Balcony, Mountain View | Blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/124000000/123380000/123379900/123379847/58768499.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, Balcony, Mountain View | Blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/124000000/123380000/123379900/123379847/fdd5b240.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/124000000/123380000/123379900/123379847/3be06efc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### MatesHouse-La Cappelluccia byHomeAndMore

[](https://www.expedia.com/San-Potito-Sannitico-Hotels-MatesHouse-La-Cappelluccia-ByHomeAndMore.h123379847.Hotel-Information)

San Potito Sannitico

[](https://www.expedia.com/San-Potito-Sannitico-Hotels-MatesHouse-La-Cappelluccia-ByHomeAndMore.h123379847.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/117000000/116510000/116500200/116500169/dc69837f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/117000000/116510000/116500200/116500169/9c80ea7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/117000000/116510000/116500200/116500169/w1170h1462x0y19-e7c01c73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/117000000/116510000/116500200/116500169/w1170h1463x0y12-2367b23c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Jenny's House 5 minutes from the A1 Caianello exit.

[](https://www.expedia.com/Marzano-Appio-Hotels-Jennys-House-5-Minutes-From-The-A1-Caianello-Exit.h116500169.Hotel-Information)

Campania

$92 nightly

$92 total

Mar 1 - Mar 2

Total with taxes and fees

[](https://www.expedia.com/Marzano-Appio-Hotels-Jennys-House-5-Minutes-From-The-A1-Caianello-Exit.h116500169.Hotel-Information)

![Dining](https://images.trvl-media.com/lodging/119000000/118650000/118645800/118645787/ab54b319.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/119000000/118650000/118645800/118645787/b5f1893e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/119000000/118650000/118645800/118645787/f23a52ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/119000000/118650000/118645800/118645787/ce2714f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Carmela Cerasuolo Filignano House

[](https://www.expedia.com/Filignano-Hotels-Carmela-Cerasuolo-Filignano-House.h118645787.Hotel-Information)

Filignano

$124 nightly

$124 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Filignano-Hotels-Carmela-Cerasuolo-Filignano-House.h118645787.Hotel-Information)

![1 bedroom, WiFi](https://images.trvl-media.com/lodging/97000000/96550000/96546500/96546475/74b5f108.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/97000000/96550000/96546500/96546475/cc399f03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/97000000/96550000/96546500/96546475/b227f027.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/97000000/96550000/96546500/96546475/9cfdad37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Mini Red Hub - Design Apartment Vieni a immergerti nel verde!!! 

[](https://www.expedia.com/SantAgapito-Hotels-Mini-Red-Hub-Design-Apartment-Vieni-A-Immergerti-Nel-Verde.h96546475.Hotel-Information)

sant agapitp

$103 nightly

$103 total

Mar 10 - Mar 11

Total with taxes and fees

[](https://www.expedia.com/SantAgapito-Hotels-Mini-Red-Hub-Design-Apartment-Vieni-A-Immergerti-Nel-Verde.h96546475.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/113000000/112310000/112307000/112306952/c7c084f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/113000000/112310000/112307000/112306952/b2031af1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/113000000/112310000/112307000/112306952/a79f3002.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/113000000/112310000/112307000/112306952/e39f8624.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Gilardi Apartmets

[](https://www.expedia.com/Cusano-Mutri-Hotels-Vrbo-Property.h112306952.Hotel-Information)

Bocca della Selva

$176 nightly

$176 total

Mar 1 - Mar 2

Total with taxes and fees

[](https://www.expedia.com/Cusano-Mutri-Hotels-Vrbo-Property.h112306952.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/120000000/119200000/119190100/119190089/d20620ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/120000000/119200000/119190100/119190089/f5564ba1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/120000000/119200000/119190100/119190089/03c5b854.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/120000000/119200000/119190100/119190089/d211e0fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Daphne Estate

[](https://www.expedia.com/Vinchiaturo-Hotels-Daphne-Estate.h119190089.Hotel-Information)

Aia Vecchia

$291 nightly

$333 total

Mar 3 - Mar 4

Total with taxes and fees

[](https://www.expedia.com/Vinchiaturo-Hotels-Daphne-Estate.h119190089.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/104000000/103360000/103358400/103358356/cc55ae24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/104000000/103360000/103358400/103358356/5864966a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, oven, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/104000000/103360000/103358400/103358356/4be59816.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/104000000/103360000/103358400/103358356/61d0b961.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Tana degli Orsetti Barrea (AQ) (open-air museum) overlooking the lake

[](https://www.expedia.com/Barrea-Hotels-La-Tana-Degli-Orsetti-Barrea.h103358356.Hotel-Information)

Barrea

$373 nightly

$373 total

Mar 1 - Mar 2

Total with taxes and fees

[](https://www.expedia.com/Barrea-Hotels-La-Tana-Degli-Orsetti-Barrea.h103358356.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/104000000/103500000/103494400/103494390/908dcdc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, hair dryer, bidet, towels](https://images.trvl-media.com/lodging/104000000/103500000/103494400/103494390/8aabeb45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/104000000/103500000/103494400/103494390/7a3b612d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, hair dryer, bidet, towels](https://images.trvl-media.com/lodging/104000000/103500000/103494400/103494390/50ed5a61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Aria di Casa Experience - Independent room with private bathroom

[](https://www.expedia.com/Cassino-Hotels-Vrbo-Property.h103494390.Hotel-Information)

Cassino

$80 nightly

$82 total

Mar 1 - Mar 2

Total with taxes and fees

[](https://www.expedia.com/Cassino-Hotels-Vrbo-Property.h103494390.Hotel-Information)

![Pool](https://images.trvl-media.com/lodging/107000000/106440000/106437100/106437003/17883f37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor spa tub](https://images.trvl-media.com/lodging/107000000/106440000/106437100/106437003/79f366a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/107000000/106440000/106437100/106437003/56c66670.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/107000000/106440000/106437100/106437003/3bf344a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Home Tenuta Fortilù

[](https://www.expedia.com/Santa-Maria-Del-Molise-Hotels-Tenuta-Fortilu-Entire-Villa-Exclusively-With-Private-Pool.h106437003.Hotel-Information)

Santa Maria del Molise

$562 nightly

$562 total

Mar 2 - Mar 3

Total with taxes and fees

[](https://www.expedia.com/Santa-Maria-Del-Molise-Hotels-Tenuta-Fortilu-Entire-Villa-Exclusively-With-Private-Pool.h106437003.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/121000000/120460000/120457900/120457894/ca69d2e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/121000000/120460000/120457900/120457894/c4cb4af8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/121000000/120460000/120457900/120457894/937192a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, hair dryer, bidet, towels](https://images.trvl-media.com/lodging/121000000/120460000/120457900/120457894/b3ee10ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Casa Delle Fate

[](https://www.expedia.com/San-Gregorio-Matese-Hotels-Vrbo-Property.h120457894.Hotel-Information)

Gallo Matese

$240 nightly

$255 total

Mar 1 - Mar 2

Total with taxes and fees

[](https://www.expedia.com/San-Gregorio-Matese-Hotels-Vrbo-Property.h120457894.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/112000000/111030000/111020100/111020070/397c5f5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/112000000/111030000/111020100/111020070/964b60bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/112000000/111030000/111020100/111020070/ee3332ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/112000000/111030000/111020100/111020070/62adde76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Aunt Peppa Castel di Sangro

[](https://www.expedia.com/Castel-Di-Sangro-Hotels-Vrbo-Property.h111020070.Hotel-Information)

Castel di Sangro

$357 nightly

$357 total

Mar 2 - Mar 3

Total with taxes and fees

[](https://www.expedia.com/Castel-Di-Sangro-Hotels-Vrbo-Property.h111020070.Hotel-Information)

![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/115000000/114950000/114943800/114943800/e92bca0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/115000000/114950000/114943800/114943800/71af3876.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/115000000/114950000/114943800/114943800/7440f2f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/115000000/114950000/114943800/114943800/e7b221c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Indigo Palace - AMBRA RESIDENCE

[](https://www.expedia.com/Castel-Di-Sangro-Hotels-Indigo-Palace-AMBRA-RESIDENCE.h114943800.Hotel-Information)

Castel di Sangro

$280 nightly

$310 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Castel-Di-Sangro-Hotels-Indigo-Palace-AMBRA-RESIDENCE.h114943800.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/115000000/114300000/114294700/114294644/233f3597.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/115000000/114300000/114294700/114294644/f901e60b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/115000000/114300000/114294700/114294644/6f86b21c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, iron/ironing board, travel crib, WiFi](https://images.trvl-media.com/lodging/115000000/114300000/114294700/114294644/eef292d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Largo Zeza Fifteen Holiday Home

[](https://www.expedia.com/Bojano-Hotels-Vrbo-Property.h114294644.Hotel-Information)

Bojano

$481 nightly

$481 total

Mar 1 - Mar 2

Total with taxes and fees

[](https://www.expedia.com/Bojano-Hotels-Vrbo-Property.h114294644.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-14&endDate=2026-03-15&regionId=6123603&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

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## 

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## Find vacation rentals that suit your style

Private vacation homes

[](https://www.expedia.com/Hotel-Search?destination=Isernia%2C+Molise%2C+Italy&regionId=6123603&latLong=41.596043%2C14.233161&adults=2&startDate=2026-05-29&d1=2026-05-29&endDate=2026-06-01&d2=2026-06-01&lodging=VACATION_HOME)

Villas

[](https://www.expedia.com/Hotel-Search?destination=Isernia%2C+Molise%2C+Italy&regionId=6123603&latLong=41.596043%2C14.233161&adults=2&startDate=2026-05-29&d1=2026-05-29&endDate=2026-06-01&d2=2026-06-01&lodging=VILLA)

Apartments

[](https://www.expedia.com/Hotel-Search?destination=Isernia%2C+Molise%2C+Italy&regionId=6123603&latLong=41.596043%2C14.233161&adults=2&startDate=2026-05-29&d1=2026-05-29&endDate=2026-06-01&d2=2026-06-01&lodging=APARTMENT)

Cabins

[](https://www.expedia.com/Hotel-Search?destination=Isernia%2C+Molise%2C+Italy&regionId=6123603&latLong=41.596043%2C14.233161&adults=2&startDate=2026-05-29&d1=2026-05-29&endDate=2026-06-01&d2=2026-06-01&lodging=CABIN)

Cottages

[](https://www.expedia.com/Hotel-Search?destination=Isernia%2C+Molise%2C+Italy&regionId=6123603&latLong=41.596043%2C14.233161&adults=2&startDate=2026-05-29&d1=2026-05-29&endDate=2026-06-01&d2=2026-06-01&lodging=COTTAGE)

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## Top Isernia Hotel Reviews

![Hotel Tiffany's](https://images.trvl-media.com/lodging/8000000/7180000/7179500/7179473/84737001_y.jpg)

### Hotel Tiffany's

10/10 Excellent

"We had a great stay. Staff were welcoming and the room was clean and bright."

[](https://expedia.com/Roccaraso-Hotels-Hotel-Tiffanys.h7179473.Hotel-Information)

![Hotel Villa Danilo](https://images.trvl-media.com/lodging/23000000/22350000/22348300/22348293/1af69b37_y.jpg)

### Hotel Villa Danilo

10/10 Excellent

"All was very pleasant and the room was warm! "

[](https://expedia.com/Gamberale-Hotels-Hotel-Villa-Danilo.h22348293.Hotel-Information)

![5 Miglia Hotel & SPA](https://images.trvl-media.com/lodging/17000000/16710000/16704600/16704505/702cb441_y.jpg)

### 5 Miglia Hotel & SPA

6/10 Okay

"We never got to the hotel because I had a bad fall on the morning we were due to travel and so we had to cancel the trip. I was very disappointed not to be able to travel but hopefully I will get there another time. "

[](https://expedia.com/Rivisondoli-Hotels-5-Miglia-Hotel-SPA.h16704505.Hotel-Information)

![Best Western Hotel Rocca](https://images.trvl-media.com/lodging/4000000/3980000/3974100/3974048/118b47f4_y.jpg)

### Best Western Hotel Rocca

8/10 Good

"Had a wonderful dinner. Shower was a bit small and the safe didn’t work but the staff were very helpful and nice "

[](https://expedia.com/Cassino-Hotels-Best-Western-Hotel-Rocca.h3974048.Hotel-Information)

![Hotel La Pace](https://images.trvl-media.com/lodging/19000000/18580000/18580000/18579979/abf303cf_y.jpg)

### Hotel La Pace

10/10 Excellent

"We would stay here again."

[](https://expedia.com/Cassino-Hotels-Hotel-La-Pace.h18579979.Hotel-Information)

![Hotel Il Tiglio](https://images.trvl-media.com/lodging/4000000/3500000/3495100/3495089/f8dbec4a_y.jpg)

### Hotel Il Tiglio

10/10 Excellent

"Mario was fantastic, personable, friendly, and took care of me at check in, booked a restaurant, etc..."

[](https://expedia.com/Castel-Di-Sangro-Hotels-Il-Tiglio-Hotel.h3495089.Hotel-Information)

## Find out more about Isernia

**Everything you need to know about Isernia vacation rentals**

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Isernia vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Isernia vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

**Isernia vacation rentals: An excellent choice for every season**

Whenever you want to travel, a warm welcome awaits you in Isernia. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Isernia in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $68 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

**How to find incredible deals on Isernia rentals**

At Expedia, we put the best Isernia vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Isernia rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Isernia vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Isernia. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

## Explore a world of travel with Expedia

- Trending destinations on Expedia.com
- All accommodation types in Isernia

### Trending destinations on Expedia.com

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- [Myrtle Beach Vacation Rentals ](https://www.expedia.com/Myrtle-Beach-Vacation-Rentals.d601685.Travel-Guide-VacationRentals)
- [Orange Beach Vacation Rentals ](https://www.expedia.com/Orange-Beach-Vacation-Rentals.d9136.Travel-Guide-VacationRentals)
- [Pigeon Forge Vacation Rentals ](https://www.expedia.com/Pigeon-Forge-Vacation-Rentals.d8264.Travel-Guide-VacationRentals)
- [Ocean City Vacation Rentals ](https://www.expedia.com/Ocean-City-Vacation-Rentals.d9151.Travel-Guide-VacationRentals)
- [Outer Banks Vacation Rentals ](https://www.expedia.com/Outer-Banks-Vacation-Rentals.d602135.Travel-Guide-VacationRentals)
- [San Diego Vacation Rentals ](https://www.expedia.com/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals)
- [Siesta Key Vacation Rentals ](https://www.expedia.com/Siesta-Key-Vacation-Rentals.d6881.Travel-Guide-VacationRentals)
- [Galveston Vacation Rentals ](https://www.expedia.com/Galveston-Vacation-Rentals.d1341.Travel-Guide-VacationRentals)
- [Clearwater Beach Vacation Rentals ](https://www.expedia.com/Clearwater-Beach-Vacation-Rentals.d10759.Travel-Guide-VacationRentals)
- [Palm Springs Vacation Rentals ](https://www.expedia.com/Palm-Springs-Vacation-Rentals.d180676.Travel-Guide-VacationRentals)
- [Florida Keys Vacation Rentals ](https://www.expedia.com/Florida-Keys-Vacation-Rentals.d6023765.Travel-Guide-VacationRentals)
- [Lake Tahoe Vacation Rentals ](https://www.expedia.com/South-Lake-Tahoe-Vacation-Rentals.d10150.Travel-Guide-VacationRentals)
- [Lake of the Ozarks Vacation Rentals ](https://www.expedia.com/Lake-Ozark-Vacation-Rentals.d177772.Travel-Guide-VacationRentals)
- [Florida Vacation Rentals ](https://www.expedia.com/Destinations-In-Florida.d211.Vacation-Rental-Destinations)
- [Hawaii Vacation Rentals ](https://www.expedia.com/Destinations-In-Hawaii.d213.Vacation-Rental-Destinations)
- [Michigan Vacation Rentals ](https://www.expedia.com/Destinations-In-Michigan.d224.Vacation-Rental-Destinations)

- [Villas in Isernia ](https://expedia.com/Isernia-Villas.d6123603-aaVillas.Travel-Guide-Accommodation)

## Frequently asked questions

### Can I find a vacation rental in Isernia?

### What are some of the best vacation rentals that Isernia has to offer?

### What’s there to see and do in Isernia?

### What’s a vacation rental in Isernia like?

### Expedia's Latest Trends

Hotels

- [Hotels in Pietrabbondante](https://expedia.com/Pietrabbondante-Hotels.d3000026979.Travel-Guide-Hotels)
- [4 Star Hotels in Colletorto](https://expedia.com/4Star-Colletorto-Hotels.s40-0-d3000384494.Travel-Guide-Filter-Hotels)
- [5 Star Hotels in Baranello](https://expedia.com/5Star-Baranello-Hotels.s50-0-d3000402099.Travel-Guide-Filter-Hotels)
- [Hotels in Termoli](https://expedia.com/Termoli-Hotels.d6048892.Travel-Guide-Hotels)
- [Hotels in Campomarino](https://expedia.com/Campomarino-Hotels.d6094809.Travel-Guide-Hotels)
- [Hotels in Frosolone](https://expedia.com/Frosolone-Hotels.d6129280.Travel-Guide-Hotels)

Flights

- [Cheap Flights to Termoli](https://expedia.com/Cheap-Flights-To-Termoli.d6048892.Travel-Guide-Flights)
- [Cheap Flights to Longano](https://expedia.com/Cheap-Flights-To-Longano.d3000458242.Travel-Guide-Flights)
- [Cheap Flights to San Massimo](https://expedia.com/Cheap-Flights-To-San-Massimo.d6145372.Travel-Guide-Flights)
- [Ferrazzano Flights](https://expedia.com/lp/flights/3000387672/flights-from-ferrazzano)

Cars

- [Car rentals in Larino](https://expedia.com/Car-Rentals-In-Larino.d3000027772.Car-Rental-Guide)

Activities

- [Things to do in Campobasso](https://expedia.com/Things-To-Do-In-Campobasso.d6056122.Travel-Guide-Activities)

Packages

- [Campochiaro Vacation](https://expedia.com/Campochiaro.d3000706270.Destination-Travel-Guides)
- [Campobasso Vacation](https://expedia.com/Campobasso.d6056122.Destination-Travel-Guides)

General

- [Visit Scapoli](https://expedia.com/Scapoli.dx3000436004)
- [Visit Baranello](https://expedia.com/Baranello.dx3000402099)
- [Visit Campomarino](https://expedia.com/Campomarino.dx6094809)
- [Visit Monteroduni](https://expedia.com/Monteroduni.dx3000395935)
- [Visit Capracotta](https://expedia.com/Capracotta.dx6123706)
- [Visit Campochiaro](https://expedia.com/Campochiaro.dx3000706270)
- [Visit Duronia](https://expedia.com/Duronia.dx3000446787)
- [Visit Sepino](https://expedia.com/Sepino.dx6129282)
- [Visit Castelmauro](https://expedia.com/Castelmauro.dx3000473215)
- [Visit Bonefro](https://expedia.com/Bonefro.dx6129283)
- [Visit Termoli](https://expedia.com/Termoli.dx6048892)
- [Visit Matrice](https://expedia.com/Matrice.dx3000475452)
- [Visit Petrella Tifernina](https://expedia.com/Petrella-Tifernina.dx553248634467763417)
- [Visit Roccavivara](https://expedia.com/Roccavivara.dx6148708)
- [Visit Sant'Elia a Pianisi](https://expedia.com/SantElia-A-Pianisi.dx3000475872)
- [Visit Colletorto](https://expedia.com/Colletorto.dx3000384494)

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