Title: Midsize Car Rentals in Downtown San Antonio - Expedia.com ![](https://images.trvl-media.com/place/800120/c427a760-8f08-4152-8ff2-5ee8720d9068.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Midsize Car Rental Companies in Downtown San Antonio - ![protection illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__protection.svg) ### Change your mind Penalty-free cancellation on many/select car rentals - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Treat yourself One Key members save 10% or more on over 1 million car rentals [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![package illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__package.svg) ### Shop smart Compare car suppliers and package your flight, hotel, and car to save ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=CTG_SPRING_PROMO_800120) ## Frequently asked questions ### How can I get a cheap midsize car rental in Downtown San Antonio with Expedia? ### How much does it cost to rent a midsize car in Downtown San Antonio? ### How old do you have to be to rent a midsize car in Downtown San Antonio? ### Why should I rent a midsize car in Downtown San Antonio? ### How can I rent a midsize car in Downtown San Antonio? ### Why should I rent a midsize car through Expedia? ### What happens if I need to cancel my Downtown San Antonio midsize car rental reservation? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [San Antonio Hotels ](https://www.expedia.com/San-Antonio-Hotels.d178303.Travel-Guide-Hotels) - [Cheap Hotels in San Antonio ](https://www.expedia.com/San-Antonio-Hotels-Cheap-Hotels.0-0-d178303-tCheapHotels.Travel-Guide-Filter-Hotels) - [Hotels with Kitchenettes in San Antonio ](https://www.expedia.com/San-Antonio-Hotels-Hotels-With-Kitchens.0-0-d178303-tHotelswithKitchens.Travel-Guide-Filter-Hotels) - [Hotels with an Indoor Pool in San Antonio ](https://www.expedia.com/San-Antonio-Hotels-Hotels-With-Indoor-Pool.0-0-d178303-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in San Antonio ](https://www.expedia.com/San-Antonio-Hotels-Pet-Friendly-Hotel.0-0-d178303-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Cabin Rentals in San Antonio ](https://www.expedia.com/San-Antonio-Cabins.d178303-aaCabins.Travel-Guide-Accommodation) - [Hotels near Henry B. González Convention Center ](https://www.expedia.com/Henry-B-Gonzalez-Convention-Center-Hotels.0-l502603-0.Travel-Guide-Filter-Hotels) - [Motels in San Antonio ](https://www.expedia.com/San-Antonio-Motels.d178303-aaMotels.Travel-Guide-Accommodation) - [Resorts in San Antonio ](https://www.expedia.com/San-Antonio-Resorts.d178303-aaResorts.Travel-Guide-Accommodation) - [Hotels near Alamo ](https://www.expedia.com/Alamo-Hotels.0-l502604-0.Travel-Guide-Filter-Hotels) - [Hotels with a Lazy River in San Antonio ](https://www.expedia.com/San-Antonio-Hotels-Hotels-With-A-Lazy-River.0-0-d178303-tHotelswithaLazyRiver.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in San Antonio ](https://www.expedia.com/San-Antonio-Hotels-Hotels-With-Hot-Tubs.0-0-d178303-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Hotels with Suites in San Antonio ](https://www.expedia.com/San-Antonio-Hotels-Hotel-Suites.0-0-d178303-tHotelSuites.Travel-Guide-Filter-Hotels) - [Hotels with Free Airport Shuttle in San Antonio ](https://www.expedia.com/San-Antonio-Hotels-Hotels-With-Free-Airport-Shuttle.0-0-d178303-tHotelswithFreeAirportShuttle.Travel-Guide-Filter-Hotels) - [Romantic Hotels in San Antonio ](https://www.expedia.com/San-Antonio-Hotels-Romantic-Hotel.0-0-d178303-tRomanticHotel.Travel-Guide-Filter-Hotels) - [Hotels near Aztec Theater ](https://www.expedia.com/Aztec-Theater-Hotels.0-l6082341-0.Travel-Guide-Filter-Hotels) - [Hotels near San Antonio Majestic Theater ](https://www.expedia.com/San-Antonio-Majestic-Theater-Hotels.0-l502621-0.Travel-Guide-Filter-Hotels) - [Marriott Hotels & Resorts in San Antonio ](https://www.expedia.com/San-Antonio-Hotels-Marriott-Hotels-Resorts.0-0-d178303--bMarriottHotelsResorts.Travel-Guide-Filter-Hotels) - [Family Hotels in San Antonio ](https://www.expedia.com/San-Antonio-Hotels-Family-Hotel.0-0-d178303-tFamilyHotel.Travel-Guide-Filter-Hotels) - [Waterpark Hotels in San Antonio ](https://www.expedia.com/San-Antonio-Hotels-Waterpark-Hotels.0-0-d178303-tWaterparkHotels.Travel-Guide-Filter-Hotels) - [5 Star Hotels in San Antonio ](https://www.expedia.com/5Star-San-Antonio-Hotels.s50-0-d178303.Travel-Guide-Filter-Hotels) - [Motel 6 Hotels in San Antonio ](https://www.expedia.com/San-Antonio-Hotels-Motel-6.0-0-d178303--bMotel6.Travel-Guide-Filter-Hotels) - [Hotels with Early Check-in in San Antonio ](https://www.expedia.com/San-Antonio-Hotels-Hotel-With-Early-Check-In.0-0-d178303-thotelwithearlycheckin.Travel-Guide-Filter-Hotels) - [Extended Stay Hotels in San Antonio ](https://www.expedia.com/San-Antonio-Hotels-Extended-Stay-Hotels.0-0-d178303-tExtendedStayHotels.Travel-Guide-Filter-Hotels) - [B&B in San Antonio ](https://www.expedia.com/San-Antonio-Bed-And-Breakfast.d178303-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Adults Only Resorts & in San Antonio ](https://www.expedia.com/San-Antonio-Hotels-Adults-Only-Resorts.0-0-d178303-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Hotels near San Antonio Convention & Visitors Bureau ](https://www.expedia.com/San-Antonio-Convention-Visitors-Bureau-Hotels.0-l553248621561866443-0.Travel-Guide-Filter-Hotels) - [4 Star Hotels in San Antonio ](https://www.expedia.com/4Star-San-Antonio-Hotels.s40-0-d178303.Travel-Guide-Filter-Hotels) - [Hotels with Free Breakfast in San Antonio ](https://www.expedia.com/San-Antonio-Hotels-Hotels-With-Complimentary-Breakfast.0-0-d178303-tHotelswithComplimentaryBreakfast.Travel-Guide-Filter-Hotels) - [Luxury Hotels in San Antonio ](https://www.expedia.com/San-Antonio-Hotels-Luxury-Hotel.0-0-d178303-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Hotels near San Antonio River ](https://www.expedia.com/San-Antonio-River-Hotels.0-l553248621532643645-0.Travel-Guide-Filter-Hotels) - [Hotels with Connecting Rooms in San Antonio ](https://www.expedia.com/San-Antonio-Hotels-Hotels-With-Adjoining-Rooms.0-0-d178303-tHotelswithAdjoiningRooms.Travel-Guide-Filter-Hotels) - [Hotels near Charline McCombs Empire Theatre ](https://www.expedia.com/Charline-McCombs-Empire-Theatre-Hotels.0-l553248621532643637-0.Travel-Guide-Filter-Hotels) - [Hotels with Balconies in San Antonio ](https://www.expedia.com/San-Antonio-Hotels-Hotels-With-Balconies.0-0-d178303-tHotelswithBalconies.Travel-Guide-Filter-Hotels) - [Resorts & Hotels with Spas in San Antonio ](https://www.expedia.com/San-Antonio-Hotels-Spa-Hotel.0-0-d178303-tSpaHotel.Travel-Guide-Filter-Hotels) - [Hotels near Alamodome ](https://www.expedia.com/Alamodome-Hotels.0-l502630-0.Travel-Guide-Filter-Hotels) - [Hotels with a Swim-up Bar in San Antonio ](https://www.expedia.com/San-Antonio-Hotels-Hotels-With-Swimup-Bar.0-0-d178303-tHotelswithSwimupBar.Travel-Guide-Filter-Hotels) - [Hotels near Tower Life Building ](https://www.expedia.com/Tower-Life-Building-Hotels.0-l6229096-0.Travel-Guide-Filter-Hotels) - [Hotels near Hertzberg Circus Museum ](https://www.expedia.com/Hertzberg-Circus-Museum-Hotels.0-l553248621563218855-0.Travel-Guide-Filter-Hotels) - [Hotels near Briscoe Western Art Museum ](https://www.expedia.com/Briscoe-Western-Art-Museum-Hotels.0-l553248621561866445-0.Travel-Guide-Filter-Hotels) - [Vacation Homes in San Antonio ](https://www.expedia.com/San-Antonio-Private-Vacation-Homes.d178303-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Honeymoon Resorts & in San Antonio ](https://www.expedia.com/San-Antonio-Hotels-Honeymoon-Hotels.0-0-d178303-tHoneymoonHotels.Travel-Guide-Filter-Hotels) - [La Quinta Inn & Suites Hotels in San Antonio ](https://www.expedia.com/San-Antonio-Hotels-La-Quinta-Inn-Suites.0-0-d178303--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) - [Hotel Wedding Venues Hotels in San Antonio ](https://www.expedia.com/San-Antonio-Hotels-Wedding-Hotels.0-0-d178303-tWeddingHotels.Travel-Guide-Filter-Hotels) - [Historic Hotels in San Antonio ](https://www.expedia.com/San-Antonio-Hotels-Historic-Hotel.0-0-d178303-tHistoricHotel.Travel-Guide-Filter-Hotels) - [Hotels with smoking rooms in San Antonio ](https://www.expedia.com/San-Antonio-Hotels-Hotels-With-Smoking-Rooms.0-0-d178303-tHotelswithsmokingrooms.Travel-Guide-Filter-Hotels) - [Hotels near Hall of Fins and Feathers ](https://www.expedia.com/Hall-Of-Fins-And-Feathers-Hotels.0-l553248621532643631-0.Travel-Guide-Filter-Hotels) - [Golf Hotels in San Antonio ](https://www.expedia.com/San-Antonio-Hotels-Golf-Hotel.0-0-d178303-tGolfHotel.Travel-Guide-Filter-Hotels) - [Hotels near Cathedral of San Fernando ](https://www.expedia.com/Cathedral-Of-San-Fernando-Hotels.0-l502627-0.Travel-Guide-Filter-Hotels) - [Boutique Hotels in San Antonio ](https://www.expedia.com/San-Antonio-Hotels-Boutique-Hotel.0-0-d178303-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Hotels near Buckhorn Saloon and Museum ](https://www.expedia.com/Buckhorn-Saloon-And-Museum-Hotels.0-l6083127-0.Travel-Guide-Filter-Hotels) - [Beach Hotels in San Antonio ](https://www.expedia.com/San-Antonio-Hotels-Beach-Hotel.0-0-d178303-tBeachHotel.Travel-Guide-Filter-Hotels) - [Hotels with Bars in San Antonio ](https://www.expedia.com/San-Antonio-Hotels-Bar-Hotel.0-0-d178303-tBarHotel.Travel-Guide-Filter-Hotels) - [Flights to San Antonio ](https://www.expedia.com/Cheap-Flights-To-San-Antonio.d178303.Travel-Guide-Flights) - [Flights from San Antonio ](https://www.expedia.com/lp/flights/178303/flights-from-san-antonio) - [San Antonio Vacations ](https://www.expedia.com/San-Antonio.d178303.Destination-Travel-Guides) - [Visit San Antonio ](https://www.expedia.com/San-Antonio.dx178303) - [All inclusive Vacation Packages San Antonio ](https://www.expedia.com/lp/theme-vacations/all-inclusive-vacations/178303/San-Antonio) - [Alamo ](https://www.expedia.com/Alamo-Downtown-San-Antonio.d502604.Vacation-Attraction) - [San Antonio River ](https://www.expedia.com/San-Antonio-River-Texas.d553248621532643645.Vacation-Attraction) - [Aztec Theater ](https://www.expedia.com/Aztec-Theater-Downtown-San-Antonio.d6082341.Vacation-Attraction) - [Where to stay in San Antonio ](https://www.expedia.com/San-Antonio.dx178303.Where-To-Stay) - [Briscoe Western Art Museum ](https://www.expedia.com/Briscoe-Western-Art-Museum-Downtown-San-Antonio.d553248621561866445.Vacation-Attraction) - [Ripley's Believe It or Not! ](https://www.expedia.com/Ripleys-Believe-It-Or-Not-Downtown-San-Antonio.d6083157.Vacation-Attraction) - [Tower Life Building ](https://www.expedia.com/Tower-Life-Building-Downtown-San-Antonio.d6229096.Vacation-Attraction) - [Plaza de las Islas ](https://www.expedia.com/Plaza-De-Las-Islas-Downtown-San-Antonio.d553248621563219139.Vacation-Attraction) - [Hertzberg Circus Museum ](https://www.expedia.com/Hertzberg-Circus-Museum-Downtown-San-Antonio.d553248621563218855.Vacation-Attraction) - [San Antonio Majestic Theater ](https://www.expedia.com/San-Antonio-Majestic-Theater-Downtown-San-Antonio.d502621.Vacation-Attraction) - [Main Plaza ](https://www.expedia.com/Main-Plaza-Downtown-San-Antonio.d6230538.Vacation-Attraction) - [Hall of Fins and Feathers ](https://www.expedia.com/Hall-Of-Fins-And-Feathers-Downtown-San-Antonio.d553248621532643631.Vacation-Attraction) - [St Joseph Catholic Church ](https://www.expedia.com/St-Joseph-Catholic-Church-Downtown-San-Antonio.d553248621532643644.Vacation-Attraction) - [The Founders Monument ](https://www.expedia.com/The-Founders-Monument-Downtown-San-Antonio.d664000506731417600.Vacation-Attraction) - [Cathedral of San Fernando ](https://www.expedia.com/Cathedral-Of-San-Fernando-Downtown-San-Antonio.d502627.Vacation-Attraction) - [The Amazing Mirror Maze ](https://www.expedia.com/The-Amazing-Mirror-Maze-Downtown-San-Antonio.d553248621532643635.Vacation-Attraction) - [Car rentals near San Antonio ](https://www.expedia.com/Car-Rentals-In-San-Antonio.d178303.Car-Rental-Guide) - [Van Car Rentals in San Antonio ](https://www.expedia.com/Van-Car-Rentals-In-San-Antonio.d178303-tVan.Car-Rental-Guide-Class) - [Luxury Car Rentals in San Antonio ](https://www.expedia.com/Luxury-Car-Rentals-In-San-Antonio.d178303-tLuxury.Car-Rental-Guide-Class) - [Convertible Car Rentals in San Antonio ](https://www.expedia.com/Convertible-Car-Rentals-In-San-Antonio.d178303-tConvertible.Car-Rental-Guide-Class) - [Pickup Car Rentals in San Antonio ](https://www.expedia.com/Pickup-Car-Rentals-In-San-Antonio.d178303-tPickup.Car-Rental-Guide-Class) - [Suv Car Rentals in San Antonio ](https://www.expedia.com/SUV-Car-Rentals-In-San-Antonio.d178303-tSUV.Car-Rental-Guide-Class) - [Minivan Car Rentals in San Antonio ](https://www.expedia.com/Minivan-Car-Rentals-In-San-Antonio.d178303-tMinivan.Car-Rental-Guide-Class) - [Sportscar Car Rentals in San Antonio ](https://www.expedia.com/Sportscar-Car-Rentals-In-San-Antonio.d178303-tSportscar.Car-Rental-Guide-Class) - [Economy Car Rentals in San Antonio ](https://www.expedia.com/Economy-Car-Rentals-In-San-Antonio.d178303-tEconomy.Car-Rental-Guide-Class) - [Mini Car Rentals in San Antonio ](https://www.expedia.com/Mini-Car-Rentals-In-San-Antonio.d178303-tMini.Car-Rental-Guide-Class) - [Standard Car Rentals in San Antonio ](https://www.expedia.com/Standard-Car-Rentals-In-San-Antonio.d178303-tStandard.Car-Rental-Guide-Class) - [Fullsize Car Rentals in San Antonio ](https://www.expedia.com/Fullsize-Car-Rentals-In-San-Antonio.d178303-tFullsize.Car-Rental-Guide-Class) - [Premium Car Rentals in San Antonio ](https://www.expedia.com/Premium-Car-Rentals-In-San-Antonio.d178303-tPremium.Car-Rental-Guide-Class) - [Midsize Car Rentals in San Antonio ](https://www.expedia.com/Midsize-Car-Rentals-In-San-Antonio.d178303-tMidsize.Car-Rental-Guide-Class) - [Luxury Car Rentals in Alamo Plaza ](https://www.expedia.com/Luxury-Car-Rentals-In-Alamo-Plaza.d6229132-tLuxury.Car-Rental-Guide-Class) - [Premium Car Rentals in Alamo Plaza ](https://www.expedia.com/Premium-Car-Rentals-In-Alamo-Plaza.d6229132-tPremium.Car-Rental-Guide-Class) - [Fullsize Car Rentals near Henry B. González Convention Center ](https://www.expedia.com/Fullsize-Car-Rentals-In-Henry-B-Gonzalez-Convention-Center.d502603-tFullsize.Car-Rental-Guide-Class) - [Budget Rental Cars in San Antonio ](https://www.expedia.com/Budget-Car-Rentals-In-San-Antonio.d178303-c39.Car-Rental-Guide-Suppliers) - [Car rentals near Charline McCombs Empire Theatre ](https://www.expedia.com/Car-Rentals-In-Charline-McCombs-Empire-Theatre.d553248621532643637.Car-Rental-Guide) - [Car rentals near San Antonio River ](https://www.expedia.com/Car-Rentals-In-San-Antonio-River.d553248621532643645.Car-Rental-Guide) - [Fox Rental Cars Rental Cars in San Antonio ](https://www.expedia.com/Fox-Rental-Cars-Car-Rentals-In-San-Antonio.d178303-c19.Car-Rental-Guide-Suppliers) - [Hertz Rental Cars in San Antonio ](https://www.expedia.com/Hertz-Car-Rentals-In-San-Antonio.d178303-c40.Car-Rental-Guide-Suppliers) - [Avis Rental Cars in San Antonio ](https://www.expedia.com/Avis-Car-Rentals-In-San-Antonio.d178303-c41.Car-Rental-Guide-Suppliers) - [Car rentals near River Walk ](https://www.expedia.com/Car-Rentals-In-River-Walk.d6125866.Car-Rental-Guide) - [San Antonio Vacation Rentals ](https://www.expedia.com/San-Antonio-Vacation-Rentals.d178303.Travel-Guide-VacationRentals) - [Things to do in San Antonio ](https://www.expedia.com/Things-To-Do-In-San-Antonio.d178303.Travel-Guide-Activities)