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Compare 335 hotels close to Odessa Regional Medical Center with room rates, reviews, and availability. Most hotels are fully refundable.

Odessa Marriott Hotel & Conference Center

4.0 star property
9.0 out of 10, Wonderful, (432)
"Great place to stay in Odessa. We want to go back just to stay at this place "
$169 nightly
The price is $194
Sep 19 - Sep 20
Total with taxes and fees
Odessa Marriott Hotel & Conference Center

Holiday Inn Express & Suites Odessa I-20 by IHG

2.5 star property
8.8 out of 10, Excellent, (437)
"WE LOVE THIS HOTEL "
$93 nightly
The price is $107
Sep 12 - Sep 13
Total with taxes and fees
Holiday Inn Express & Suites Odessa I-20 by IHG

MainStay Suites Odessa I-20

2.5 star property
8.2 out of 10, Very Good, (269)
"We encountered room dirtyness, bugs in the restroom. "
$71 nightly
The price is $82
Sep 5 - Sep 6
Total with taxes and fees
MainStay Suites Odessa I-20

Motel 6 Odessa, TX - 2nd Street

2.0 star property
7.8 out of 10, Good, (487)
"The place was clean and well kept. The Rooms were clean and confortable. I willl be staying here when in Odessa."
$60 nightly
The price is $69
Aug 30 - Aug 31
Total with taxes and fees
Motel 6 Odessa, TX - 2nd Street

SureStay Plus Hotel by Best Western Odessa

3.0 star property
7.4 out of 10, Good, (65)
"Very nice place to stay "
$84 nightly
The price is $97
Sep 3 - Sep 4
Total with taxes and fees
SureStay Plus Hotel by Best Western Odessa

Villa West Inn

2.0 star property
7.4 out of 10, Good, (172)
"Very friendly staff "
$64 nightly
The price is $74
Aug 30 - Aug 31
Total with taxes and fees
Villa West Inn

DELUX INN

2.5 star property
7.2 out of 10, Good, (19)
"Best hotel "
$65 nightly
The price is $75
Aug 30 - Aug 31
Total with taxes and fees
DELUX INN

Motel 6 Odessa, TX

2.0 star property
6.8 out of 10, (517)
"I really enjoyed my stay the room was real clean and the bed was really comfortable I would stay there again"
$54 nightly
The price is $63
Sep 1 - Sep 2
Total with taxes and fees
Motel 6 Odessa, TX

Staybridge Suites Odessa - Interstate HWY 20 by IHG

3.0 star property
8.8 out of 10, Excellent, (131)
"Nice and clean property. Friendly staff."
$101 nightly
The price is $116
Sep 13 - Sep 14
Total with taxes and fees
Staybridge Suites Odessa - Interstate HWY 20 by IHG

TownePlace Suites by Marriott Odessa

3.0 star property
9.0 out of 10, Wonderful, (505)
"Great service and breakfast was very good."
$89 nightly
The price is $102
Sep 6 - Sep 7
Total with taxes and fees
TownePlace Suites by Marriott Odessa

Hawthorn Extended Stay by Wyndham Odessa

3.5 star property
8.6 out of 10, Excellent, (255)
"Will definitely book again!"
$89 nightly
The price is $102
Aug 30 - Aug 31
Total with taxes and fees
Hawthorn Extended Stay by Wyndham Odessa

Candlewood Suites Odessa by IHG

2.5 star property
8.6 out of 10, Excellent, (189)
"It was a smaller place than i have stayed before, it does not have a pool, but still great place to stay."
$99 nightly
The price is $114
Aug 30 - Aug 31
Total with taxes and fees
Candlewood Suites Odessa by IHG

Fairfield Inn & Suites Odessa

2.5 star property
8.8 out of 10, Excellent, (399)
"Great stay. "
$85 nightly
The price is $98
Sep 6 - Sep 7
Total with taxes and fees
Fairfield Inn & Suites Odessa

Sleep Inn & Suites Odessa

2.5 star property
8.6 out of 10, Excellent, (458)
"great spot."
$72 nightly
The price is $83
Sep 27 - Sep 28
Total with taxes and fees
Sleep Inn & Suites Odessa

Hampton Inn by Hilton Odessa

2.5 star property
8.6 out of 10, Excellent, (349)
"Always a great place to stay!!!"
$100 nightly
The price is $116
Sep 13 - Sep 14
Total with taxes and fees
Hampton Inn by Hilton Odessa

MCM Elegante Hotel and Conference Center Odessa

3.5 star property
8.8 out of 10, Excellent, (1006)
"Restaurant, Starbucks, and Salon on site is great! "
$111 nightly
The price is $128
Aug 30 - Aug 31
Total with taxes and fees
MCM Elegante Hotel and Conference Center Odessa

Holiday Inn Express Hotel & Suites Odessa by IHG

2.5 star property
8.8 out of 10, Excellent, (389)
"Cinnamon rolls reason I stay at express First floor accommodations "
$88 nightly
The price is $101
Sep 5 - Sep 6
Total with taxes and fees
Holiday Inn Express Hotel & Suites Odessa by IHG

Studio 6 Odessa, TX

2.5 star property
8.0 out of 10, Very Good, (220)
"The guy at front deskt at night was very nice to us (my son and I).. the place was pretty clean and quiet to spend the night. They refund me the $50 fee the next day."
$75 nightly
The price is $86
Aug 30 - Aug 31
Total with taxes and fees
Studio 6 Odessa, TX

Executive Inn Odessa

2.5 star property
7.4 out of 10, Good, (168)
"Enjoyed my stay. Quiet area and no annoying neighbors!"
$37 nightly
The price is $43
Aug 31 - Sep 1
Total with taxes and fees
Executive Inn Odessa

Holiday Inn Odessa by IHG

3.0 star property
8.6 out of 10, Excellent, (425)
"Great Staff and Great Room"
$88 nightly
The price is $101
Sep 7 - Sep 8
Total with taxes and fees
Holiday Inn Odessa by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's the area like around Odessa Regional Medical Center?

Odessa Regional Medical Center is located in Odessa. This family-friendly area is known for its array of dining options. If you're looking for a convenient place to stay, check out the 10 hotels and other accommodations you'll find within a mile.

What's the best hotel to stay close to Odessa Regional Medical Center?

Adjacent to Odessa Regional Medical Center, Odessa Marriott Hotel & Conference Center is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices within a few miles include MCM Grande Hotel FunDome Odessa and MCM Elegante Hotel and Conference Center Odessa.

How many hotels can I expect to find near Odessa Regional Medical Center?

Expedia has 10 hotels and other accommodations within a mile from Odessa Regional Medical Center.

If I need to cancel the hotel reservation for my stay near Odessa Regional Medical Center, will I receive a refund?

Yes! Most hotel reservations are refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a reservation that's non-refundable, it might still be possible to cancel it and receive a refund within 24 hours of booking. Add dates, click "Search", then use the "fully refundable" filter to view the top deals on offer near Odessa Regional Medical Center.

Where can I learn more about changing or cancelling my trip in the area near Odessa Regional Medical Center?

To find more details about picking new dates or cancelling your stay near Odessa Regional Medical Center, head over to our customer service page.

What can I see and do near Odessa Regional Medical Center?

Study the collections at White-Pool House, Parker House Museum, or Ellen Noel Art Museum. Create some family memories at Altitude Trampoline Park and Fun City. Attractions like Globe of the Great Southwest and Presidential Museum and Leadership Library highlight the local culture.