Santa Croce Vacations from $992

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Your Santa Croce Vacation

Our Santa Croce vacation packages are a fast and practical way to plan and reserve your next adventure. Uncover the true character of this unique neighborhood without the hassle of having to organize everything yourself. Some top nearby attractions to see during your trip to Santa Croce include Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Expedia can put your plans into action. Book your ultimate Santa Croce vacation now.

The Latest Santa Croce Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Aurum Firenze

Aurum Firenze

4 out of 5
Historic Centre of Florence
Save 100% on your flight
per person
Sep 24 - Sep 30
found 23 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
7.6/10 Good! (1,012 reviews)
This is amazing little property, ran by a great staff. You have the overlook the small size of the rooms for the value. If you are there to walk around Florence and only there to relax and shower this is your place! The staff is kind and respectful, the WiFi is good, and since we were there in the summer we were thankful for the good air conditioning.

Reviewed on Jul 21, 2025

Aurum Uffizi

Aurum Uffizi

4 out of 5
Historic Centre of Florence
Save 100% on your flight
per person
Sep 24 - Sep 30
found 22 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
7.8/10 Good! (1,001 reviews)
Everything was perfect! Thank you!!

Reviewed on Jul 20, 2025

Palazzo Firenze by Baglioni Hotels & Resorts

Palazzo Firenze by Baglioni Hotels & Resorts

5 out of 5
Historic Centre of Florence
Save 100% on your flight
per person
Sep 24 - Sep 30
found 23 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
9.4/10 Exceptional! (228 reviews)
I VERY MUCH ENJOYED THE STAY

Reviewed on Jul 18, 2025

The Moon Boutique Hotel & Spa

The Moon Boutique Hotel & Spa

4 out of 5
Historic Centre of Florence
Save 100% on your flight
per person
Oct 7 - Oct 13
found 22 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
9.6/10 Exceptional! (462 reviews)
Hands down the best place we have stayed. They accommodated to go breakfasts for our tours, arranged taxis, made cappuccino when we were heading out the door. Wonderful experience

Reviewed on Jun 6, 2025

LHP River Club

LHP River Club

5 out of 5
Santa Croce
Save 100% on your flight
per person
Sep 24 - Sep 30
found 23 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
No reviews

Where to stay in Santa Croce

Find the best Santa Croce areas and neighborhoods for the activities you enjoy most. Learn more about Santa Croce
Arcetri showing a bridge and a river or creek

Historic Centre of Florence

10 out of top 10 points of interest in this area

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Find hotels in Historic Centre of Florence

Santa Croce Hotel Deals

Plaza Hotel Lucchesi

Plaza Hotel Lucchesi

4 out of 5
Lungarno Della Zecca Vecchia 38, Florence, FI
Fully refundableReserve now, pay when you stay
$231 nightly
The price is $271 total per night from Aug 22 to Aug 23
$271 total
Aug 22 - Aug 23
Total includes taxes and fees
9.2/10 Wonderful! (978 reviews)
"The perfect Florence stay. Pricey but worth it."

Reviewed on Jul 22, 2025

Plaza Hotel Lucchesi
Hotel Balestri

Hotel Balestri

4 out of 5
Piazza Mentana 7, Florence, FI
Fully refundableReserve now, pay when you stay
$188 nightly
The price is $223 total per night from Jul 31 to Aug 1
$223 total
Jul 31 - Aug 1
Total includes taxes and fees
9.2/10 Wonderful! (952 reviews)
"Loved the location and cleanliness, only complaint was the pillows and beds weren't comfortable. (Mattress were hard and pillows too thin)"

Reviewed on Jul 16, 2025

Hotel Balestri
FH55 Grand Hotel Mediterraneo

FH55 Grand Hotel Mediterraneo

4 out of 5
Lungarno del Tempio, 44, Florence, FI
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $121 total per night from Aug 1 to Aug 2
$121 total
Aug 1 - Aug 2
Total includes taxes and fees
8/10 Very Good! (884 reviews)
"Good hotel very clean and just 25 mins walk into Florence"

Reviewed on Jul 16, 2025

FH55 Grand Hotel Mediterraneo
See all 843 properties in Santa Croce
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

All Inclusive Vacations

All Inclusive Vacations

Beach Vacations

Beach Vacations

Kid Friendly Vacations

Kid Friendly Vacations

Discover the most popular places to visit in Santa Croce

Piazza Santa Croce featuring a statue or sculpture

Piazza Santa Croce

Italy’s most famous soccer game takes place here once a year, but the square is better known as a nighttime hangout of choice for young people.

Piazza Santa Croce
Basilica of Santa Croce which includes heritage architecture, a statue or sculpture and religious aspects

Basilica of Santa Croce

Glorious tombs mark the resting place of Michelangelo, Galileo and many other Italian greats in the largest Franciscan church in the world.

Basilica of Santa Croce
Not a hidden gem, but still a great spot.

National Central Library of Florence

Find out about the history of Florence when you take a trip to National Central Library of Florence. Discover the area's beautiful sunsets and notable monuments.

National Central Library of Florence

Things to do

Florence: Pasta Cooking Class with Unlimited Wine

Florence: Pasta Cooking Class with Unlimited Wine

$34
per adult
90% of travellers recommend
Florence: Pasta Cooking Class with Unlimited Wine
People riding scooters in Tuscany

Tuscany Vintage Vespa Tour

$153
per adult
100% of travellers recommend
Tuscany Vintage Vespa Tour
Santa Maria Novella

Visit Florence in golf car with Fiorentine tuorist guide

$81
per adult
100% of travellers recommend
Visit Florence in golf car with Fiorentine tuorist guide
See all activities in Florence
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.