Santa Croce Vacations from $1,222
Book a Hotel + Flight or Car together to unlock savings
Your Santa Croce Vacation
Our Santa Croce vacation packages are a fast and practical way to plan and reserve your next adventure. Uncover the true character of this unique neighborhood without the hassle of having to organize everything yourself. Some top nearby attractions to see during your trip to Santa Croce include Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Expedia can put your plans into action. Book your ultimate Santa Croce vacation now.
The Latest Santa Croce Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Grand Hotel Cavour
Historic Centre of Florence
Save 100% on your flight
Price was $2,203, price is now $1,433 per person
$1,433
per person
Oct 17 - Oct 22
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Florence (FLR)
9.2/10 Wonderful! (1,000 reviews)
Great location, helpful staff, don’t miss the rooftop bar at night for a great view of the Duomo
Reviewed on Jul 29, 2026
Eurostars Florence Boutique
Historic Centre of Florence
Price was $2,156, price is now $1,536 per person
$1,536
per person
Oct 3 - Oct 8
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Florence (FLR)
8.6/10 Excellent! (494 reviews)
Very good location. Clean hotel. Our ac was broken but they handled us a new room inmediately. The hotel is confortable and size of the rooms are decent. Bigger than average in the area.
Reviewed on Jun 26, 2026
Precise Tale Poggio Alla Sala
Save 100% on your flight
Price was $5,537, price is now $3,957 per person
$3,957
per person
Sep 5 - Sep 11
found 6 hours ago
Roundtrip flight included
New York (JFK) to Florence (FLR)
9.6/10 Exceptional! (154 reviews)
Magical location, pools, staff, property.
Reviewed on Jul 19, 2026
Where to stay in Santa Croce
Find the best Santa Croce areas and neighborhoods for the activities you enjoy most. Learn more about Santa Croce
Historic Centre of Florence
10 out of top 10 points of interest in this area
Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.
Santa Croce Hotel Deals
Plaza Hotel Lucchesi
Lungarno Della Zecca Vecchia 38 Florence FI
Fully refundableReserve now, pay when you stay
$225 nightly
The price is $263 total per night from Aug 30 to Aug 31
$263 total
Aug 30 - Aug 31
Total with taxes and fees
9.4/10 Exceptional! (1,012 reviews)
"Excellent staff and incredible view. Large bed, large bedroom. All very clean."
Reviewed on Jul 29, 2026
FH55 Grand Hotel Mediterraneo
Lungarno del Tempio, 44 Florence FI
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $132 total per night from Jul 31 to Aug 1
$132 total
Jul 31 - Aug 1
Total with taxes and fees
8.2/10 Very Good! (1,008 reviews)
"Beautiful propert, close to restaurants and shopping, scenic options."
Reviewed on Jul 29, 2026
Hotel Balestri
Piazza Mentana 7 Florence FI
Fully refundableReserve now, pay when you stay
$164 nightly
The price is $197 total per night from Aug 18 to Aug 19
$197 total
Aug 18 - Aug 19
Total with taxes and fees
9.4/10 Exceptional! (1,008 reviews)
"Location, views and balcony were great. Service from staff was great also."
Reviewed on Jul 24, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Santa Croce attractions
Things to do
City Sightseeing Florence Hop-on Hop-off Bus Tour
$33
per adult
76% of travellers recommend
The Best of Tuscany Tour: Siena, San Gimignano, Pisa and Lunch at a Winery
$78
per adult
98% of travellers recommend
Florence Vespa Tour: Tuscan Hills, Food and Chianti Wine
$126
per adult
100% of travellers recommend
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.