Santa Croce Vacations
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Your Santa Croce Vacation
Our Santa Croce vacation packages are a fast and practical way to plan and reserve your next adventure. Uncover the true character of this unique neighborhood without the hassle of having to organize everything yourself. Some top nearby attractions to see during your trip to Santa Croce include Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Expedia can put your plans into action. Book your ultimate Santa Croce vacation now.
Price found within the past 48 hours. Click for updated prices.
- Aurum Uffizi
Jul 22 - Jul 29Aurum Uffizi + Flight
Historic Centre of Florence6 nights7.6/10 - Good (1,008 reviews)"WiFi is slow, no iron in the room, no blackout window shade, no staff after 9pm in case of emergency there is no one to assist. Hotel should note those things to guests so we can book accordingly"Reviewed June 3, 2026Roundtrip • Dallas (DFW) - Florence (FLR)DFW - FLR • 1 stop FLR - DFW • 1 stop$1,898$1,287found 1 day agoper traveler - Donati Luxury Tower Suites
Jul 19 - Jul 24Donati Luxury Tower Suites + Flight
Historic Centre of Florence4 nights9.8/10 - Exceptional (66 reviews)"Agradable estancia. Excelente servicio. La habitación la mantenían siempre limpia. Todo queda cerca del área. Muy recomendable"Reviewed May 23, 2026Roundtrip • New York (JFK) - Venice (VCE)JFK - VCE • Nonstop VCE - JFK • Nonstop - Borgo Scopeto Wine & Country Relais
Aug 11 - Aug 18Borgo Scopeto Wine & Country Relais + Flight
Castelnuovo Berardenga6 nights9.4/10 - Exceptional (200 reviews)"Amazing hotel"Reviewed May 1, 2026Roundtrip • New York (JFK) - Rome (FCO)JFK - FCO • Nonstop FCO - JFK • Nonstop - Precise Tale Poggio Alla Sala
Jul 22 - Jul 29Precise Tale Poggio Alla Sala + Flight
Montepulciano6 nights9.6/10 - Exceptional (142 reviews)"Beautiful stay for our honeymoon. This is definitely a place to go and feel at peace in the Tuscan countryside. 15 min away from some wineries and 20 min away from Montepulciano. Great balance of feeling relaxed by the spa and pool with some quick getaways. Lastly, the restaurant was beyond excellent. Expensive but well worth it."Reviewed May 23, 2026Roundtrip • Los Angeles (LAX) - Rome (FCO)LAX - FCO • 1 stop FCO - LAX • 1 stop - Dimora Palanca Boutique & SPA
Aug 15 - Aug 26Dimora Palanca Boutique & SPA + Flight
Historic Centre of Florence10 nights9.2/10 - Wonderful (66 reviews)Roundtrip • New York (EWR) - Florence (FLR)EWR - FLR • 1 stop FLR - EWR • 1 stop
Where to stay in Santa Croce
Find the best Santa Croce areas and neighborhoods for the activities you enjoy most. Learn more about Santa Croce
Historic Centre of Florence
9 out of top 10 points of interest in this area
Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.
Santa Croce Hotel Deals
FH55 Grand Hotel Mediterraneo
Lungarno del Tempio, 44 Florence FI
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $183 total per night from Jul 3 to Jul 4
$183 total
Jul 3 - Jul 4
Total with taxes and fees
8.2/10 Very Good! (1,001 reviews)
"Spacious and nice lobby Helpful staff and excellent breakfast buffet Good air conditioning Clean room. Appreciated the welcome gift for my service dog"
Reviewed on May 27, 2026
Aurum Uffizi
Via Osteria Del Guanto 6 Florence FI
$248 nightly
The price is $290 total per night from Jul 1 to Jul 2
$290 total
Jul 1 - Jul 2
Total with taxes and fees
7.6/10 Good! (1,008 reviews)
"WiFi is slow, no iron in the room, no blackout window shade, no staff after 9pm in case of emergency there is no one to assist. Hotel should note those things to guests so we can book accordingly"
Reviewed on Jun 3, 2026
Plaza Hotel Lucchesi
Lungarno Della Zecca Vecchia 38 Florence FI
Fully refundableReserve now, pay when you stay
$306 nightly
The price is $353 total per night from Jul 5 to Jul 6
$353 total
Jul 5 - Jul 6
Total with taxes and fees
9.4/10 Exceptional! (1,004 reviews)
"Clean Upscale"
Reviewed on Jun 2, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Santa Croce
Piazza Santa Croce
4/5(5 reviews)
Italy’s most famous soccer game takes place here once a year, but the square is better known as a nighttime hangout of choice for young people.
Basilica of Santa Croce
4.5/5(1,001 reviews)
Glorious tombs mark the resting place of Michelangelo, Galileo and many other Italian greats in the largest Franciscan church in the world.
Mercato di Sant'Ambrogio
5/5(1 review)
You can browse for the perfect souvenirs at Mercato di Sant'Ambrogio during your trip to Florence. Discover the acclaimed art scene and notable monuments in this vibrant area.
Things to do
City Sightseeing Florence Hop-on Hop-off Bus Tour
$34
per adult
76% of travellers recommend
Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour
$27
per adult
80% of travellers recommend
The Best of Tuscany in One Day Sightseeing Tour
$123
per adult
98% of travellers recommend
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.