Cheap Flights from Mesa (AZA) to San Diego (SAN)

Popular airlines from Phoenix - Mesa Gateway Airport (AZA) to San Diego Intl. Airport (SAN)

    notification illustration

    Be in the know

    Get alerts if flight prices drop or rise*
    deals illustration

    Book smarter

    Save up to 30% on select hotels after you book a flight*
    trophy illustration

    Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Frequently asked questions

How much does a flight from Phoenix - Mesa Gateway Airport (AZA) to San Diego Intl. Airport (SAN) cost?
Secure a cheap one-way flight or cheap return flight from Phoenix - Mesa Gateway Airport (AZA) to San Diego Intl. Airport (SAN) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Phoenix - Mesa Gateway Airport (AZA) to San Diego Intl. Airport (SAN)?
The cheapest month to fly from AZA to SAN is , when demand is low. Off-peak season is typically when you'll find cheap fares for travel between these airports.
Which airlines fly direct from Phoenix - Mesa Gateway Airport (AZA) to San Diego Intl. Airport (SAN)?
There's no direct route from Mesa, AZ (AZA-Phoenix - Mesa Gateway) to San Diego Intl. Airport (SAN). However, you can find other airports offering nonstop flights. Hop on your plane at Sky Harbor Intl. Airport (PHX) and fly straight to San Diego without layovers.
What is the cheapest airline that flies from Phoenix - Mesa Gateway Airport (AZA) to San Diego Intl. Airport (SAN)?
To find the cheapest airline that'll fly you from AZA to SAN, use Expedia's filter tool. Tailor your search based on your travel needs, such as preferred carriers and cabin class. You can then sort your results by "Price (lowest to highest)" to list the most affordable options first.
How many flights per day from Phoenix - Mesa Gateway Airport (AZA) to San Diego Intl. Airport (SAN)?
You'll have to catch a flight with a layover when traveling from Phoenix - Mesa Gateway Airport (AZA) to San Diego Intl. Airport (SAN). There are no daily direct flights on this route. However, just filter your search to include one or two stops to discover an option that works for you.
What day of the week has the most flights from AZA to SAN?
Friday is typically the busiest day for flights, while Tuesday tends to be the quietest.* Remember that flight schedules can vary based on various factors, such as the airline and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Phoenix - Mesa Gateway Airport (AZA) to San Diego Intl. Airport (SAN)?
Opt for a flight from Phoenix - Mesa Gateway Airport (AZA) to San Diego Intl. Airport (SAN) that leaves before 3 PM to reduce the risk of cancellations and delays. Later departures have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Phoenix - Mesa Gateway Airport (AZA) to San Diego Intl. Airport (SAN) last-minute?
Last-minute bookings from AZA to SAN are usually more expensive. To lock in the best prices, start searching for flights well ahead of time. That said, if you're flexible with your travel plans, it's possible to find a cheap fare just before your departure.
Is it cheaper to book an AZA to SAN flight and hotel package?
Opting for an AZA to SAN flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your trip in one place. Pick from our wide range of stays and then add car rentals, flights and activities to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Phoenix - Mesa Gateway Airport (AZA) to San Diego Intl. Airport (SAN)?
You can usually reschedule or cancel your AZA to SAN flight. However, for bookings made more than 24 hours ago, additional fees may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find more details on our Customer Service portal.

Travel information

Origin airport
Phoenix - Mesa Gateway
Destination airport
San Diego Intl.
Distance
322 mi

Book with confidence

Mesa to San Diego Flights

The cheapest times to fly from Mesa to San Diego

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Mesa to San Diego are during the month of . You can find some of the cheapest flights from Mesa to San Diego with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Mesa to San Diego

Sunday is one of the best days to book for cheap flights from Mesa to San Diego: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Mesa to San Diego

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Mesa to San Diego in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Mesa to San Diego flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Mesa to San Diego airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Mesa to San Diego Flights

Explore a world of travel with Expedia

*Available to One Key members.