$356 Cheap Flights from Lisbon (LIS) to Medellín (MDE)

View $356 flight on Sun, Apr 12, 2026Opens in a new window

Popular airlines from Humberto Delgado Airport (LIS) to Jose Maria Cordova Intl. Airport (MDE)

Cheap Flights from Lisbon to Medellín (LIS-MDE)

Prices were available within the past 7 days and start at $356 for one-way flights and $675 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

TAP Portugal
Sun, Apr 12 - Wed, Apr 22
LIS
Lisbon
MDE
Medellin
$675 Roundtrip, found 6 days ago
$675
Roundtrip
found 6 days ago
Select TAP Portugal flight, departing Sun, Apr 12 from Lisbon to Medellin, returning Wed, Apr 22, priced at $675 found 6 days ago
TAP Portugal
Sun, Apr 12 - Wed, Apr 22
LIS
Lisbon
MDE
Medellin
$721 Roundtrip, found 6 days ago
$721
Roundtrip
found 6 days ago
Select TAP Portugal flight, departing Sun, Apr 12 from Lisbon to Medellin, returning Wed, Apr 22, priced at $721 found 6 days ago
TAP Portugal
Sun, Apr 12 - Wed, Apr 22
LIS
Lisbon
MDE
Medellin
$724 Roundtrip, found 6 days ago
$724
Roundtrip
found 6 days ago
Select TAP Portugal flight, departing Sun, Apr 12 from Lisbon to Medellin, returning Wed, Apr 22, priced at $724 found 6 days ago
TAP Portugal
Sun, Apr 12 - Wed, Apr 22
LIS
Lisbon
MDE
Medellin
$725 Roundtrip, found 6 days ago
$725
Roundtrip
found 6 days ago
Select TAP Portugal flight, departing Sun, Apr 12 from Lisbon to Medellin, returning Wed, Apr 22, priced at $725 found 6 days ago
TAP Portugal
Tue, Nov 4 - Sat, Nov 8
LIS
Lisbon
MDE
Medellin
$915 Roundtrip, found 18 hours ago
$915
Roundtrip
found 18 hours ago
Select TAP Portugal flight, departing Tue, Nov 4 from Lisbon to Medellin, returning Sat, Nov 8, priced at $915 found 18 hours ago
KLM
Wed, Jan 14 - Wed, Jan 21
LIS
Lisbon
MDE
Medellin
$950 Roundtrip, found 18 hours ago
$950
Roundtrip
found 18 hours ago
Select KLM flight, departing Wed, Jan 14 from Lisbon to Medellin, returning Wed, Jan 21, priced at $950 found 18 hours ago
TAP Portugal
Tue, Nov 4 - Sat, Nov 8
LIS
Lisbon
MDE
Medellin
$961 Roundtrip, found 18 hours ago
$961
Roundtrip
found 18 hours ago
Select TAP Portugal flight, departing Tue, Nov 4 from Lisbon to Medellin, returning Sat, Nov 8, priced at $961 found 18 hours ago
Air Europa
Thu, Feb 5 - Tue, Feb 10
LIS
Lisbon
MDE
Medellin
$971 Roundtrip, found 15 hours ago
$971
Roundtrip
found 15 hours ago
Select Air Europa flight, departing Thu, Feb 5 from Lisbon to Medellin, returning Tue, Feb 10, priced at $971 found 15 hours ago
United
Fri, Feb 6 - Sun, Feb 8
LIS
Lisbon
MDE
Medellin
$975 Roundtrip, found 21 hours ago
$975
Roundtrip
found 21 hours ago
Select United flight, departing Fri, Feb 6 from Lisbon to Medellin, returning Sun, Feb 8, priced at $975 found 21 hours ago
Lufthansa
Wed, Dec 3 - Tue, Jan 20
LIS
Lisbon
MDE
Medellin
$1,030 Roundtrip, found 18 hours ago
$1,030
Roundtrip
found 18 hours ago
Select Lufthansa flight, departing Wed, Dec 3 from Lisbon to Medellin, returning Tue, Jan 20, priced at $1,030 found 18 hours ago

Frequently asked questions

How much does a flight from Humberto Delgado Airport (LIS) to Jose Maria Cordova Intl. Airport (MDE) cost?
Grab a cheap one-way flight from $356 or cheap return flight from $675 from Humberto Delgado Airport (LIS) to Jose Maria Cordova Intl. Airport (MDE) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Humberto Delgado Airport (LIS) to Jose Maria Cordova Intl. Airport (MDE)?
Flying in April is a great way to save, as it's the cheapest month for flights between LIS and MDE. You'll typically find the lowest fares during off-peak months.
What is the cheapest airline that flies from Humberto Delgado Airport (LIS) to Jose Maria Cordova Intl. Airport (MDE)?
Use the filter tool on Expedia to compare different airlines and find the most affordable carrier that'll fly you from LIS to MDE. Then, sort your results by "Price (lowest to highest)" to snap up the best deal available.
How many flights per day from Humberto Delgado Airport (LIS) to Jose Maria Cordova Intl. Airport (MDE)?
You'll need to catch a flight with a layover if you're traveling from Humberto Delgado Airport (LIS) to Jose Maria Cordova Intl. Airport (MDE). Direct flights don't operate daily on this route. However, simply filter your search to include one or more stops to find the best option for your trip.
What day of the week has the most flights from LIS to MDE?
You'll usually find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can vary from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Humberto Delgado Airport (LIS) to Jose Maria Cordova Intl. Airport (MDE)?
To arrive at Jose Maria Cordova Intl. Airport (MDE) on time, book a flight that leaves Humberto Delgado Airport (LIS) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Humberto Delgado Airport (LIS) to Jose Maria Cordova Intl. Airport (MDE) last-minute?
Holding off until right before your break to book your flight from LIS to MDE often results in higher prices. While you might find some last-minute discounts, they aren't always guaranteed. Keep your travel schedule open for a better chance of snagging a bargain.
Is it cheaper to book a LIS to MDE flight and hotel package?
Securing a LIS to MDE flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip all in one place. Choose from our wide range of hotels and then add car rentals, flights and activities to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Humberto Delgado Airport (LIS) to Jose Maria Cordova Intl. Airport (MDE)?
Typically, you can modify or cancel your LIS to MDE flight. However, there may be additional charges, especially if you booked more than 24 hours ago. Double-check your itinerary for the airline's fees and policies on flight changes, or if you want more details, go to our Customer Service portal.

Travel information

Origin airport
Humberto Delgado
Destination airport
José María Córdova Intl.
Airlines serving
Air Canada, Air Europa, American Airlines, Iberia, KLM, LATAM Airlines Group, Lufthansa, TAP Portugal, United
Roundtrip price
$675
Distance
4679 mi

Book with confidence

Lisbon to Medellín Flights

The cheapest times to fly from Lisbon to Medellín

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Lisbon to Medellín are during the month of April. You can find some of the cheapest flights from Lisbon to Medellín with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Lisbon to Medellín

Sunday is one of the best days to book for cheap flights from Lisbon to Medellín: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Lisbon to Medellín

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Lisbon to Medellín in 2025. You can also book with separate airlines for your outbound and return journeys, from $356 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Lisbon to Medellín flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Lisbon to Medellín airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Lisbon to Medellín Flights

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*Available to One Key members.