$275 Cheap Flights from Mobile (MOB) to Columbia (COU)

View $275 flight on Tue, Jul 28, 2026Opens in a new window

Popular airlines from Mobile Regional Airport (MOB) to Columbia, MO (COU-Columbia Regional)

Cheap Flights from Mobile to Columbia (MOB-COU)

Prices were available within the past 7 days and start at $275 for one-way flights and $544 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Fri, Jun 19 - Sun, Jun 21
MOB
Mobile
COU
Columbia
$544 Roundtrip, found 1 hour ago
$544
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Fri, Jun 19 from Mobile to Columbia, returning Sun, Jun 21, priced at $544 found 1 hour ago
American Airlines
Fri, Jun 19 - Sun, Jun 21
MOB
Mobile
COU
Columbia
$606 Roundtrip, found 1 hour ago
$606
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Fri, Jun 19 from Mobile to Columbia, returning Sun, Jun 21, priced at $606 found 1 hour ago
American Airlines
Fri, Jun 19 - Sun, Jun 21
MOB
Mobile
COU
Columbia
$640 Roundtrip, found 1 hour ago
$640
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Fri, Jun 19 from Mobile to Columbia, returning Sun, Jun 21, priced at $640 found 1 hour ago
American Airlines
Fri, Jun 19 - Sun, Jun 21
MOB
Mobile
COU
Columbia
$644 Roundtrip, found 1 hour ago
$644
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Fri, Jun 19 from Mobile to Columbia, returning Sun, Jun 21, priced at $644 found 1 hour ago
American Airlines
Fri, Jun 19 - Sun, Jun 21
MOB
Mobile
COU
Columbia
$647 Roundtrip, found 1 hour ago
$647
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Fri, Jun 19 from Mobile to Columbia, returning Sun, Jun 21, priced at $647 found 1 hour ago
American Airlines
Fri, Jun 19 - Sun, Jun 21
MOB
Mobile
COU
Columbia
$658 Roundtrip, found 1 hour ago
$658
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Fri, Jun 19 from Mobile to Columbia, returning Sun, Jun 21, priced at $658 found 1 hour ago
American Airlines
Fri, Jun 19 - Sun, Jun 21
MOB
Mobile
COU
Columbia
$668 Roundtrip, found 1 hour ago
$668
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Fri, Jun 19 from Mobile to Columbia, returning Sun, Jun 21, priced at $668 found 1 hour ago
American Airlines
Fri, Jun 19 - Sun, Jun 21
MOB
Mobile
COU
Columbia
$684 Roundtrip, found 1 hour ago
$684
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Fri, Jun 19 from Mobile to Columbia, returning Sun, Jun 21, priced at $684 found 1 hour ago
American Airlines
Fri, Jun 19 - Sun, Jun 21
MOB
Mobile
COU
Columbia
$686 Roundtrip, found 1 hour ago
$686
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Fri, Jun 19 from Mobile to Columbia, returning Sun, Jun 21, priced at $686 found 1 hour ago
United
Fri, Jun 19 - Sun, Jun 21
MOB
Mobile
COU
Columbia
$1,308 Roundtrip, found 1 hour ago
$1,308
Roundtrip
found 1 hour ago
Select United flight, departing Fri, Jun 19 from Mobile to Columbia, returning Sun, Jun 21, priced at $1,308 found 1 hour ago

Frequently asked questions

How much does a flight from Mobile, AL (MOB-Mobile Regional) to Columbia, MO (COU-Columbia Regional) cost?
You can find cheap one-way flights from $275 and cheap return flights from $544 Mobile, AL (MOB-Mobile Regional) to Columbia, MO (COU-Columbia Regional) with Expedia. One-way flights generally range between $432 and $906, and roundtrip flights usually range from $689 to $1601. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Mobile, AL (MOB-Mobile Regional) to Columbia, MO (COU-Columbia Regional) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Mobile, AL (MOB-Mobile Regional) to Columbia, MO (COU-Columbia Regional)?
The cheapest month to fly from MOB to COU is June when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Mobile, AL (MOB-Mobile Regional) to Columbia, MO (COU-Columbia Regional)?
Enter MOB to COU and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Mobile, AL (MOB-Mobile Regional) to Columbia, MO (COU-Columbia Regional)?
American Airlines is one of the cheapest airlines offering connecting flights from Mobile (MOB) to Columbia (COU), with round-trip tickets starting from around $508. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Mobile, AL (MOB-Mobile Regional) to Columbia, MO (COU-Columbia Regional)?
To find a cheap flight from Mobile, AL (MOB-Mobile Regional) to Columbia, MO (COU-Columbia Regional), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Mobile, AL (MOB-Mobile Regional) to Columbia, MO (COU-Columbia Regional)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Mobile, AL (MOB-Mobile Regional) to Columbia, MO (COU-Columbia Regional)?
The earliest flight from Mobile, AL (MOB) to Columbia, MO (COU) typically departs at around 5:05 AM, operated by American Airlines. This is a seasonal service available in November. An early flight allows you to maximize your time in Columbia. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Mobile, AL (MOB-Mobile Regional) to Columbia, MO (COU-Columbia Regional)?
The most popular departure times for flights from Mobile, AL (MOB) to Columbia, MO (COU) are in the late morning, from 9am to 12pm. About 57% of passengers prefer this time window. Many major carriers, including American Airlines and United Airlines, offer flights during this window. This timing works well because it allows you to arrive in Columbia with plenty of time to explore.
How long does it take to fly from Mobile, AL (MOB-Mobile Regional) to Columbia, MO (COU-Columbia Regional)?
Flights from MOB to COU with one stop typically take around 6 hours 30 minutes, covering approximately 606 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Mobile, AL (MOB-Mobile Regional) to Columbia, MO (COU-Columbia Regional)?
Select the "Business class" and "First class" filters when looking for MOB to COU flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Mobile, AL (MOB-Mobile Regional) to Columbia, MO (COU-Columbia Regional) flight with Expedia?
It's easy to earn miles on a Mobile, AL (MOB-Mobile Regional) to Columbia, MO (COU-Columbia Regional) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Columbia from Mobile Regional (MOB)?
When traveling from Mobile Regional (MOB) to Columbia, you can fly into Columbia Regional (COU) and Columbia Metropolitan (CAE). Some flights may connect through major hubs like George Bush Intercontinental (IAH), Washington Dulles Intl. (IAD), Hartsfield-Jackson Atlanta Intl. (ATL) before reaching Columbia. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Mobile, AL (MOB-Mobile Regional) to Columbia, MO (COU-Columbia Regional) at the last minute?
Typically, booking a last minute flight from Mobile, AL (MOB-Mobile Regional) to Columbia, MO (COU-Columbia Regional) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Mobile, AL (MOB-Mobile Regional) to Columbia, MO (COU-Columbia Regional) flight and hotel package?
Securing a Mobile, AL (MOB-Mobile Regional) to Columbia, MO (COU-Columbia Regional) Columbia Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Mobile, AL (MOB-Mobile Regional) to Columbia, MO (COU-Columbia Regional)?
If you booked your Mobile, AL (MOB-Mobile Regional) to Columbia, MO (COU-Columbia Regional) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Mobile Regional
Destination airport
Columbia Regional
Roundtrip price
$544
Distance
605 mi

Book with confidence

Mobile to Columbia Flights

The cheapest times to fly from Mobile to Columbia

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Mobile to Columbia are during the month of June. You can find some of the cheapest flights from Mobile to Columbia with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Mobile to Columbia

Sunday is one of the best days to book for cheap flights from Mobile to Columbia: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Mobile to Columbia

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Mobile to Columbia in 2026. You can also book with separate airlines for your outbound and return journeys, from $275 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Mobile to Columbia flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Mobile to Columbia airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Mobile to Columbia Flights

*Flight schedules are subject to change.

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*Available to One Key members.