$271 Cheap Flights from Panama City (PTY) to Houston (HOU)

View $271 flight on Tue, Feb 3, 2026Opens in a new window

Popular airlines from Tocumen Intl. Airport (PTY) to Houston William Hobby Airport (HOU)

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Cheap Flights from Panama City to Houston (PTY-HOU)

Prices were available within the past 7 days and start at $271 for one-way flights and $474 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Mon, Jan 12 - Mon, Jan 26
PTY
Panama City
HOU
Houston
$474 Roundtrip, found 5 days ago
$474
Roundtrip
found 5 days ago
Select Delta flight, departing Mon, Jan 12 from Panama City to Houston, returning Mon, Jan 26, priced at $474 found 5 days ago
Delta
Tue, Sep 1 - Tue, Sep 8
PTY
Panama City
HOU
Houston
$484 Roundtrip, found 4 days ago
$484
Roundtrip
found 4 days ago
Select Delta flight, departing Tue, Sep 1 from Panama City to Houston, returning Tue, Sep 8, priced at $484 found 4 days ago
Delta
Wed, Jan 21 - Mon, Feb 9
PTY
Panama City
HOU
Houston
$486 Roundtrip, found 5 days ago
$486
Roundtrip
found 5 days ago
Select Delta flight, departing Wed, Jan 21 from Panama City to Houston, returning Mon, Feb 9, priced at $486 found 5 days ago
Delta
Tue, Sep 1 - Tue, Sep 8
PTY
Panama City
HOU
Houston
$503 Roundtrip, found 5 days ago
$503
Roundtrip
found 5 days ago
Select Delta flight, departing Tue, Sep 1 from Panama City to Houston, returning Tue, Sep 8, priced at $503 found 5 days ago
Delta
Mon, Jan 12 - Mon, Jan 26
PTY
Panama City
HOU
Houston
$539 Roundtrip, found 5 days ago
$539
Roundtrip
found 5 days ago
Select Delta flight, departing Mon, Jan 12 from Panama City to Houston, returning Mon, Jan 26, priced at $539 found 5 days ago
Delta
Mon, Jan 12 - Mon, Jan 26
PTY
Panama City
HOU
Houston
$605 Roundtrip, found 5 days ago
$605
Roundtrip
found 5 days ago
Select Delta flight, departing Mon, Jan 12 from Panama City to Houston, returning Mon, Jan 26, priced at $605 found 5 days ago
Delta
Tue, Sep 1 - Tue, Sep 8
PTY
Panama City
HOU
Houston
$634 Roundtrip, found 5 days ago
$634
Roundtrip
found 5 days ago
Select Delta flight, departing Tue, Sep 1 from Panama City to Houston, returning Tue, Sep 8, priced at $634 found 5 days ago
Delta
Tue, Jan 13 - Sat, Feb 21
PTY
Panama City
HOU
Houston
$663 Roundtrip, found 5 days ago
$663
Roundtrip
found 5 days ago
Select Delta flight, departing Tue, Jan 13 from Panama City to Houston, returning Sat, Feb 21, priced at $663 found 5 days ago
Delta
Wed, Jan 21 - Sat, Feb 7
PTY
Panama City
HOU
Houston
$668 Roundtrip, found 5 days ago
$668
Roundtrip
found 5 days ago
Select Delta flight, departing Wed, Jan 21 from Panama City to Houston, returning Sat, Feb 7, priced at $668 found 5 days ago
Delta
Tue, Jan 13 - Sat, Feb 21
PTY
Panama City
HOU
Houston
$675 Roundtrip, found 5 days ago
$675
Roundtrip
found 5 days ago
Select Delta flight, departing Tue, Jan 13 from Panama City to Houston, returning Sat, Feb 21, priced at $675 found 5 days ago
Delta
Tue, Jan 13 - Tue, Jan 20
PTY
Panama City
HOU
Houston
$715 Roundtrip, found 4 days ago
$715
Roundtrip
found 4 days ago
Select Delta flight, departing Tue, Jan 13 from Panama City to Houston, returning Tue, Jan 20, priced at $715 found 4 days ago
Delta
Tue, Jan 13 - Mon, Jan 19
PTY
Panama City
HOU
Houston
$716 Roundtrip, found 4 days ago
$716
Roundtrip
found 4 days ago
Select Delta flight, departing Tue, Jan 13 from Panama City to Houston, returning Mon, Jan 19, priced at $716 found 4 days ago

Find the cheapest month to fly from Panama City (PTY) to Houston (HOU)

February is typically the cheapest month to fly

From $452 - $1,123 per traveler.

Alternative airports near Houston

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to George Bush Intercontinental IAH. Cheapest option available. Average driving time to city center is 24 minutes. Flights from $775
IAH
George Bush Intercontinental
Cheapest
Average driving time to city center24 min
Flights from $775
Flights from Panama City (PTY) to Houston (HOU)
Origin airport
Tocumen Intl.
Destination airport
William P. Hobby
Airlines serving
American Airlines, Delta
Roundtrip price
$473
Distance
1754 mi

Panama City to Houston Flights

The cheapest times to fly from Panama City to Houston

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Panama City to Houston are during the month of January. You can find some of the cheapest flights from Panama City to Houston with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Panama City to Houston

Sunday is one of the best days to book for cheap flights from Panama City to Houston: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Panama City to Houston

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Panama City to Houston in 2026. You can also book with separate airlines for your outbound and return journeys, from $271 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Panama City to Houston flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Panama City to Houston airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Tocumen Intl. Airport (PTY) to William P. Hobby Airport (HOU) cost?
Lock in a cheap one-way flight from $271 or cheap return flight from $474 from Tocumen Intl. Airport (PTY) to William P. Hobby Airport (HOU) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Tocumen Intl. Airport (PTY) to William P. Hobby Airport (HOU)?
January is the most affordable month to fly from PTY to HOU. Traveling during an off-peak travel window is often the key to finding a great deal.
What is the cheapest airline that flies from Tocumen Intl. Airport (PTY) to William P. Hobby Airport (HOU)?
To find the cheapest airline that'll fly you from PTY to HOU, use Expedia's filter tool. Tailor your search based on your travel style, such as preferred carriers and flight duration. You can then sort your results by "Price (lowest to highest)" to see the most affordable options first.
How many flights per day from Tocumen Intl. Airport (PTY) to William P. Hobby Airport (HOU)?
There are no daily nonstop flights departing from Tocumen Intl. Airport (PTY) to William P. Hobby Airport (HOU). But you can opt for flights with layovers. Filter your search results on Expedia to include one or two stops, and you'll be on your way in no time.
What day of the week has the most flights from PTY to HOU?
You'll usually find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can vary from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Tocumen Intl. Airport (PTY) to William P. Hobby Airport (HOU)?
Choose a flight from Tocumen Intl. Airport (PTY) to William P. Hobby Airport (HOU) that takes off before 3 PM to reduce the risk of cancellations. Departures after this hour have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Houston from Tocumen Intl. Airport (PTY)?
Check out your flight options from Tocumen Intl. Airport (PTY) to George Bush Intercontinental Airport (IAH). This is the only airport in Houston you can arrive at if you're taking a direct flight.
Is it cheaper to buy a plane ticket from Tocumen Intl. Airport (PTY) to William P. Hobby Airport (HOU) last-minute?
Last-minute bookings from PTY to HOU are usually more expensive. To secure the best rates, start looking for flights well ahead of time. That said, if your travel plans are flexible, it's possible to find a cheap fare right before your trip.
Is it cheaper to book a PTY to HOU flight and hotel package?
Compared with arranging flights and hotels separately, booking a PTY to HOU flight and hotel package with Expedia could lead to significant savings. What's more, having everything in one place will take the hassle out of travel planning. Simply secure your flights and select from our extensive range of hotels, then tailor your trip with extras like tours, activities and car rentals.
Can I cancel or change the date of my flight from Tocumen Intl. Airport (PTY) to William P. Hobby Airport (HOU)?
It's usually possible to reschedule or cancel your PTY to HOU flight. However, for bookings made more than 24 hours ago, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are possible and if any costs are involved. You'll also find more details on our Customer Service portal.

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*Available to One Key members.