$493 Cheap Flights from Santiago (SCL) to Columbus (CMH)

View $493 flight on Sat, Nov 15, 2025Opens in a new window

Popular airlines from Santiago Intl. Airport (SCL) to John Glenn Columbus Intl. Airport (CMH)

Cheap Flights from Santiago to Columbus (SCL-CMH)

Prices were available within the past 7 days and start at $493 for one-way flights and $734 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Mon, Dec 15 - Tue, Dec 30
SCL
Santiago
CMH
Columbus
$734 Roundtrip, found 15 hours ago
$734
Roundtrip
found 15 hours ago
Select Delta flight, departing Mon, Dec 15 from Santiago to Columbus, returning Tue, Dec 30, priced at $734 found 15 hours ago
United
Mon, Dec 15 - Wed, Dec 31
SCL
Santiago
CMH
Columbus
$734 Roundtrip, found 15 hours ago
$734
Roundtrip
found 15 hours ago
Select United flight, departing Mon, Dec 15 from Santiago to Columbus, returning Wed, Dec 31, priced at $734 found 15 hours ago
United
Thu, Dec 18 - Tue, Dec 30
SCL
Santiago
CMH
Columbus
$739 Roundtrip, found 15 hours ago
$739
Roundtrip
found 15 hours ago
Select United flight, departing Thu, Dec 18 from Santiago to Columbus, returning Tue, Dec 30, priced at $739 found 15 hours ago
LATAM Airlines Group
Mon, Dec 8 - Wed, Dec 24
SCL
Santiago
CMH
Columbus
$754 Roundtrip, found 15 hours ago
$754
Roundtrip
found 15 hours ago
Select LATAM Airlines Group flight, departing Mon, Dec 8 from Santiago to Columbus, returning Wed, Dec 24, priced at $754 found 15 hours ago
LATAM Airlines Group
Mon, Jan 26 - Wed, Feb 11
SCL
Santiago
CMH
Columbus
$759 Roundtrip, found 15 hours ago
$759
Roundtrip
found 15 hours ago
Select LATAM Airlines Group flight, departing Mon, Jan 26 from Santiago to Columbus, returning Wed, Feb 11, priced at $759 found 15 hours ago
LATAM Airlines Group
Mon, Dec 8 - Wed, Dec 24
SCL
Santiago
CMH
Columbus
$764 Roundtrip, found 2 days ago
$764
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Mon, Dec 8 from Santiago to Columbus, returning Wed, Dec 24, priced at $764 found 2 days ago
American Airlines
Wed, Nov 26 - Sat, Dec 6
SCL
Santiago
CMH
Columbus
$774 Roundtrip, found 10 hours ago
$774
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Wed, Nov 26 from Santiago to Columbus, returning Sat, Dec 6, priced at $774 found 10 hours ago
American Airlines
Wed, Nov 26 - Sat, Dec 6
SCL
Santiago
CMH
Columbus
$779 Roundtrip, found 10 hours ago
$779
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Wed, Nov 26 from Santiago to Columbus, returning Sat, Dec 6, priced at $779 found 10 hours ago
Delta
Wed, Nov 26 - Sat, Dec 6
SCL
Santiago
CMH
Columbus
$781 Roundtrip, found 10 hours ago
$781
Roundtrip
found 10 hours ago
Select Delta flight, departing Wed, Nov 26 from Santiago to Columbus, returning Sat, Dec 6, priced at $781 found 10 hours ago
Copa
Sat, Dec 13 - Fri, Jan 9
SCL
Santiago
CMH
Columbus
$1,062 Roundtrip, found 17 hours ago
$1,062
Roundtrip
found 17 hours ago
Select Copa flight, departing Sat, Dec 13 from Santiago to Columbus, returning Fri, Jan 9, priced at $1,062 found 17 hours ago

Find the cheapest month to fly from Santiago (SCL) to Columbus (CMH)

May is typically the cheapest month to fly

From $722 - $1,315 per traveler.

Alternative airports near Columbus

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to John Glenn Columbus Intl. CMH. Cheapest and Closest option available. Average driving time to city center is 10 minutes. Flights from $734
CMH
John Glenn Columbus Intl.
CheapestClosest
Average driving time to city center10 min
Flights from $734

Frequently asked questions

How much does a flight from Arturo Merino Benitez Airport (SCL) to John Glenn Columbus Intl. Airport (CMH) cost?
Lock in a cheap one-way flight from $493 or cheap return flight from $734 from Arturo Merino Benitez Airport (SCL) to John Glenn Columbus Intl. Airport (CMH) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Arturo Merino Benitez Airport (SCL) to John Glenn Columbus Intl. Airport (CMH)?
The cheapest month to fly from SCL to CMH is December, when there's less demand. Off-peak season is typically when you'll find cheap fares for travel between these airports.
What is the cheapest airline that flies from Arturo Merino Benitez Airport (SCL) to John Glenn Columbus Intl. Airport (CMH)?
Expedia's filter tool lets you easily compare airlines, flight times and fares all in one place. Choose your preferences, then sort by "Price (lowest to highest)" to find out which carrier offers the cheapest SCL to CMH flight.
How many flights per day from Arturo Merino Benitez Airport (SCL) to John Glenn Columbus Intl. Airport (CMH)?
You'll need to catch a flight with a layover when traveling from Arturo Merino Benitez Airport (SCL) to John Glenn Columbus Intl. Airport (CMH). Direct flights don't operate daily on this route. However, just filter your search to include one or two stops to find the best option for your trip.
What day of the week has the most flights from SCL to CMH?
Friday is generally the busiest day for flights, while Tuesday is often the quietest.* Just remember that flight schedules can change depending on various factors, such as the time of year and carrier.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Arturo Merino Benitez Airport (SCL) to John Glenn Columbus Intl. Airport (CMH)?
To avoid potential delays on the Arturo Merino Benitez Airport (SCL) to John Glenn Columbus Intl. Airport (CMH) route, aim to fly before 3 PM. Departures after this hour are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Arturo Merino Benitez Airport (SCL) to John Glenn Columbus Intl. Airport (CMH) last-minute?
Holding off until right before your break to book a ticket from SCL to CMH often results in higher prices. While it's possible to find some last-minute discounts, there's no guarantee. Keep your travel plans flexible to boost your chances of scoring a bargain.
Is it cheaper to book a SCL to CMH flight and hotel package?
Compared with arranging hotels and flights separately, booking a SCL to CMH flight and hotel package with Expedia could result in significant savings. Better yet, having everything in one convenient place will take the hassle out of travel planning. Simply secure your flights and choose from our wide range of hotels, then personalize your trip with other add-ons like activities, tours and car rentals.
Can I cancel or change the date of my flight from Arturo Merino Benitez Airport (SCL) to John Glenn Columbus Intl. Airport (CMH)?
If you reserved your SCL to CMH flight in the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you purchased, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal for further details.

Travel information

Origin airport
Arturo Merino Benitez
Destination airport
John Glenn Columbus Intl.
Airlines serving
Air Canada, American Airlines, Copa, Delta, LATAM Airlines Group, United
Roundtrip price
$734
Distance
5129 mi

Book with confidence

Santiago to Columbus Flights

The cheapest times to fly from Santiago to Columbus

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santiago to Columbus are during the month of December. You can find some of the cheapest flights from Santiago to Columbus with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Santiago to Columbus

Sunday is one of the best days to book for cheap flights from Santiago to Columbus: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Santiago to Columbus

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santiago to Columbus in 2025. You can also book with separate airlines for your outbound and return journeys, from $493 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santiago to Columbus flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Santiago to Columbus airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Santiago to Columbus Flights

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*Available to One Key members.