$190 Cheap American Airlines flights Charlotte (CLT) to Key West (EYW)

Landing cheap one-way American Airlines flights from CLT to EYW from $190 on Expedia couldn’t be easier — just filter by “Price (lowest to highest).” Alternatively, check out our budget-friendly return fares from $377 for your next exciting getaway.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

American Airlines flights to Key West are often more affordable in the off-peak months of September and August. Whether you’re searching for a one-way or a return ticket, you could land a better deal then.

Search for cheap American Airlines flights from Charlotte-Douglas Intl. Airport (CLT) to Key West Intl. Airport (EYW) one to three months before your departure. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. No matter the fare class and itinerary, the best day to book a domestic flight is generally Sunday and the most expensive is typically Monday. Passengers who book on a Sunday can save 6% on average compared to those who book on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

Skip the layovers and fly from Charlotte-Douglas Intl. Airport (CLT) to Key West Intl. Airport (EYW) on any of American Airlines’s 24 weekly direct flights. Make use of our “Nonstop” and “Airline” filters to find the American Airlines flight that’ll land at EYW at your preferred time.

Take off from Charlotte-Douglas Intl. Airport (CLT) for Key West Intl. Airport (EYW) on a direct American Airlines flight, and you’ll be in the air for about 2h 22m.

American Airlines operates the most flights from Charlotte-Douglas Intl. Airport (CLT) to Key West Intl. Airport (EYW) on Saturday. With up to 4 daily departures, you’ll get the most flexibility and choice on this day.

The first flight from CLT to EYW with American Airlines leaves at 9:40AM UTC-5. You’ll land at 12:08PM UTC-5. The final American Airlines flight of the day takes off at 4:47PM UTC-5 and arrives at 7:07PM UTC-5. With around 20% fewer cancellations for morning and mid-morning departures, beginning your travel day early is often the best choice.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

American Airlines flights from Charlotte-Douglas Intl. Airport (CLT) to Key West arrive at Key West Intl. Airport (EYW). This is the main entry point here.

Chances are you’ll be flying on an Airbus A319 for your American Airlines flight from Charlotte-Douglas Intl. Airport (CLT) to Key West Intl. Airport (EYW). However, you may end up on an alternative aircraft if there’s an operational need.

You can usually modify or cancel your flight, although there may be additional fees if you made your booking over 24 hours ago. Need flexible options? Use Expedia’s “Changes included” and “No cancel fee” filters to find flights that won’t charge you extra if you have to adjust your plans. To make modifications, visit “Trips,” select your flight and click on “Manage Booking” for more information.