PEN268 Cheap American Airlines flights New York (JFK) to Buffalo (BUF)

Finding cheap one-way American Airlines flights from JFK to BUF from PEN268 on Expedia couldn't be simpler — just filter by "Price (lowest to highest)." Or check out our affordable round-trip fares from PEN500 for your next getaway.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Start searching one to three months ahead of your travel date to score cheap fares on American Airlines flights from John F. Kennedy Intl. Airport (JFK) to Buffalo Niagara Intl. Airport (BUF). You can save 25% by booking your domestic flight 34 to 86 days in advance versus last-minute reservations made 6 to 12 days out. You could also reduce costs by buying your fare on a Sunday, as it's 6% cheaper on average than a Monday, the most expensive day to book.* Get your timing spot on, and you can enjoy significant savings on domestic trips.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Search American Airlines's earliest flights from JFK to BUF by selecting our "Morning" and "Early Morning" filters. Not only will you get to where you're going sooner, early departures also have a 20% less chance of being canceled.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.