$190 Cheap American Airlines flights Raleigh (RDU) to San Francisco (SFO)

You can discover budget-friendly return American Airlines flights from $309 from RDU to SFO by filtering your results from “Price (lowest to highest)” on Expedia. Or search for deals from $190 for a one-way journey.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Browse for round-trip or one-way flights to San Francisco in February or April. You could find lower fares with American Airlines during these quieter months.

Look for affordable American Airlines flights from Raleigh - Durham Intl. Airport (RDU) to San Francisco Intl. Airport (SFO) one to three months ahead of your day of departure. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. Regardless of fare type and itinerary, the best day to book a domestic flight is usually Sunday and the most expensive day is typically Monday. Passengers who book on a Sunday can save 6% on average compared to those who book their travel on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

To find out if there’s a direct route from RDU to SFO with American Airlines or another carrier, use our “Nonstop” filter when searching for tickets.

Search American Airlines’s earliest flights from RDU to SFO by selecting our “Morning” and “Early Morning” filters. Not only will you get to where you’re going sooner, early departures also experience 20% fewer cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

San Francisco Intl. Airport (SFO) is the main San Francisco hub for American Airlines flights from Raleigh - Durham Intl. Airport (RDU).

Changes are often free within 24 hours of making a booking, but your airline may charge a fee after that time. For further details about modifying your flights, check out your “Trips,” select your flight and click on “Manage Booking.” If you’d like the freedom to make changes without extra charges, check the “Changes included” or “No cancel fee” filter when planning your next getaway.