$168 Cheap Frontier Airlines flights Knoxville (TYS) to San Francisco (SFO)

Scoring cheap one-way Frontier Airlines flights from TYS to SFO from $168 on Expedia is a cinch --- just filter by "Price (lowest to highest)." Alternatively, check out our affordable return fares from $323 for your next break.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

For cheap Frontier Airlines fares from McGhee Tyson Airport (TYS) to San Francisco Intl. Airport (SFO), start searching one to three months before your intended departure. Securing domestic flights 34 to 86 days in advance could save you 25% compared to booking just 6 to 12 days ahead. The day you book can also affect how much you pay. Sunday tends to be the most affordable, while Monday is often the most expensive for domestic flights. You can save 6% on average by booking your trip on a Sunday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Find Frontier Airlines's earliest flights from TYS to SFO by checking the "Early Morning" and "Morning" filters. Not only will you arrive sooner, early departures also experience 20% fewer cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.

Travel from TYS to SFO with Frontier Airlines and you can look forward to a host of benefits including a rewarding loyalty program. When you book through Expedia as a Frontier Miles and One Key™ member, you can also earn OneKeyCash™* to redeem on select future travel purchases.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.