$69 Cheap Flights from Denver (DEN) to Knoxville (TYS)

View $69 flight on Sun, Oct 5, 2025Opens in a new window

Popular airlines from Denver Intl. Airport (DEN) to McGhee Tyson Airport (TYS)

Cheap Flights from Denver to Knoxville (DEN-TYS)

Prices were available within the past 7 days and start at $69 for one-way flights and $96 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Sun, Aug 31 - Thu, Sep 4
DEN
Denver
TYS
Knoxville
$96 Roundtrip, found 2 days ago
$96
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Sun, Aug 31 from Denver to Knoxville, returning Thu, Sep 4, priced at $96 found 2 days ago
Frontier Airlines
Sun, Sep 7 - Mon, Sep 8
DEN
Denver
TYS
Knoxville
$99 Roundtrip, found 2 days ago
$99
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Sun, Sep 7 from Denver to Knoxville, returning Mon, Sep 8, priced at $99 found 2 days ago
Frontier Airlines
Sun, Oct 5 - Thu, Oct 23
DEN
Denver
TYS
Knoxville
$102 Roundtrip, found 3 days ago
$102
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Sun, Oct 5 from Denver to Knoxville, returning Thu, Oct 23, priced at $102 found 3 days ago
Frontier Airlines
Sun, Aug 31 - Thu, Sep 4
DEN
Denver
TYS
Knoxville
$106 Roundtrip, found 2 days ago
$106
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Sun, Aug 31 from Denver to Knoxville, returning Thu, Sep 4, priced at $106 found 2 days ago
Frontier Airlines
Mon, Sep 8 - Mon, Sep 15
DEN
Denver
TYS
Knoxville
$120 Roundtrip, found 1 day ago
$120
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Mon, Sep 8 from Denver to Knoxville, returning Mon, Sep 15, priced at $120 found 1 day ago
Frontier Airlines
Sun, Oct 19 - Thu, Oct 23
DEN
Denver
TYS
Knoxville
$122 Roundtrip, found 3 days ago
$122
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Sun, Oct 19 from Denver to Knoxville, returning Thu, Oct 23, priced at $122 found 3 days ago
United
Sat, Nov 1 - Thu, Nov 6
DEN
Denver
TYS
Knoxville
$214 Roundtrip, found 10 hours ago
$214
Roundtrip
found 10 hours ago
Select United flight, departing Sat, Nov 1 from Denver to Knoxville, returning Thu, Nov 6, priced at $214 found 10 hours ago
American Airlines
Fri, Sep 26 - Wed, Oct 1
DEN
Denver
TYS
Knoxville
$219 Roundtrip, just found
$219
Roundtrip
just found
Select American Airlines flight, departing Fri, Sep 26 from Denver to Knoxville, returning Wed, Oct 1, priced at $219 just found
Delta
Fri, Sep 26 - Wed, Oct 1
DEN
Denver
TYS
Knoxville
$237 Roundtrip, just found
$237
Roundtrip
just found
Select Delta flight, departing Fri, Sep 26 from Denver to Knoxville, returning Wed, Oct 1, priced at $237 just found
Southwest Airlines
Tue, Mar 17 - Tue, Mar 24
DEN
Denver
TYS
Knoxville
$259 Roundtrip, found 6 days ago
$259
Roundtrip
found 6 days ago
Select Southwest Airlines flight, departing Tue, Mar 17 from Denver to Knoxville, returning Tue, Mar 24, priced at $259 found 6 days ago

Find the cheapest month to fly from Denver (DEN) to Knoxville (TYS)

January is typically the cheapest month to fly

From $98 - $465 per traveler.

Graph displaying average flight prices per month

Alternative airports near Knoxville

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to McGhee Tyson TYS. Cheapest and Closest option available. Average driving time to city center is 22 minutes. Flights from $279
TYS
McGhee Tyson
CheapestClosest
Average driving time to city center22 min
Flights from $279
Flights from Denver (DEN) to Knoxville (TYS)
Origin airport
Denver Intl.
Destination airport
McGhee Tyson
Airlines serving
American Airlines, Delta, Frontier Airlines, Southwest Airlines, United
Roundtrip price
$96
Distance
1159 mi
Average flight time
4 hours 56 mins

Denver to Knoxville Flights

The cheapest times to fly from Denver to Knoxville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Denver to Knoxville are during the month of August. You can find some of the cheapest flights from Denver to Knoxville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Denver to Knoxville

Sunday is one of the best days to book for cheap flights from Denver to Knoxville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Denver to Knoxville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Denver to Knoxville in 2025. You can also book with separate airlines for your outbound and return journeys, from $69 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Denver to Knoxville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Denver to Knoxville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Denver Intl. Airport (DEN) to McGhee Tyson Airport (TYS) cost?
Lock in a cheap one-way flight from $69 or cheap return flight from $96 from Denver Intl. Airport (DEN) to McGhee Tyson Airport (TYS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Denver Intl. Airport (DEN) to McGhee Tyson Airport (TYS)?
August is the most affordable month to fly from DEN to TYS. Planning your trip for the off-season is often the key to finding better fares.
Which airlines fly direct from Denver Intl. Airport (DEN) to McGhee Tyson Airport (TYS)?
You can fly directly from Denver Intl. Airport (DEN) to McGhee Tyson Airport (TYS) on a United Airlines flight.
What is the cheapest airline that flies from Denver Intl. Airport (DEN) to McGhee Tyson Airport (TYS)?
The cheapest airline to offer flights between Denver Intl. Airport (DEN) and McGhee Tyson Airport (TYS) will change depending on your travel plans. Frontier Airlines and United Airlines are just some good options offering competitive fares. Use Expedia's filters to compare airlines in one place and find the right DEN to TYS flight that fits your budget.
How many flights per day from Denver Intl. Airport (DEN) to McGhee Tyson Airport (TYS)?
Every day, an average of 2 direct flights operate from Denver Intl. Airport (DEN) to McGhee Tyson Airport (TYS). Pick the departure time that best fits your schedule.
What are the most popular departure times for flights from Denver Intl. Airport (DEN) to McGhee Tyson Airport (TYS)?
More travelers fly between DEN and TYS at 5 PM than at any other time. Rather go when it's quieter? Pick a flight outside the busiest times and it's possible you'll save on your ticket as well.
What day of the week has the most flights from DEN to TYS?
If you fly on a Sunday, you'll get the biggest range of choices for flights from Denver Intl. Airport (DEN) to McGhee Tyson Airport (TYS).
What is the earliest flight from Denver Intl. Airport (DEN) to McGhee Tyson Airport (TYS)?
Catch the earliest flight at around 9:59AM UTC-7, departing from Denver Intl. Airport (DEN). You'll be in the air for around 3h, reaching McGhee Tyson Airport (TYS) at approximately 2:59PM UTC-5.
How long does it take to fly from Denver Intl. Airport (DEN) to McGhee Tyson Airport (TYS)?
The average flight time from DEN to TYS is 2 hours and 57 minutes, covering a total distance of 1,150 mi.
What is the best time to fly from Denver Intl. Airport (DEN) to McGhee Tyson Airport (TYS)?
Book a flight from Denver Intl. Airport (DEN) to McGhee Tyson Airport (TYS) that leaves before 3 PM to reduce the likelihood of delays and cancellations. Later departures are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Knoxville from Denver Intl. Airport (DEN)?
McGhee Tyson Airport (TYS) is the only airport in Knoxville with direct flights from Denver Intl. Airport (DEN). Compare the available options and find affordable fares on Expedia.
Is it cheaper to buy a plane ticket from Denver Intl. Airport (DEN) to McGhee Tyson Airport (TYS) last-minute?
Holding off until just before your trip to book a flight from DEN to TYS often results in higher prices. While it's possible to find some last-minute discounts, they're not always guaranteed. Be flexible with your travel plans to maximize your chances of getting a bargain.
Is it cheaper to book a DEN to TYS flight and hotel package?
You'll generally save money by securing a DEN to TYS flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one convenient place. After selecting your ideal accommodations and flights, consider adding extras such as car rentals, tours and activities.
Can I cancel or change the date of my flight from Denver Intl. Airport (DEN) to McGhee Tyson Airport (TYS)?
Generally, it's possible to cancel or reschedule your DEN to TYS flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Check your airline's policies in your itinerary to see what changes are possible and if any costs are involved. You'll also find more information on our Customer Service portal.

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*Available to One Key members.