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$182 Cheap Flights from Los Angeles (LAX) to Knoxville (TYS)

Popular airlines from Los Angeles Intl. (LAX) to McGhee Tyson Airport (TYS)

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Cheap Flights from Los Angeles to Knoxville (LAX-TYS)

Prices were available within the past 7 days and start at $182 for one-way flights and $363 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Delta
United
Southwest Airlines
Southwest Airlines
United
United
Southwest Airlines
United
Alaska Airlines

Alternative airports near Knoxville

Prices were available within the past 7 days. Prices and availability are subject to change.

Find the cheapest month to fly from Los Angeles (LAX) to Knoxville (TYS)

January is typically the cheapest month to fly

From $246 - $761 per traveler.

What you need to know for your flight from Los Angeles Intl. to McGhee Tyson

Los Angeles (LAX) to Knoxville (TYS) at a glance

Explore a range of airlines providing service from Los Angeles International Airport (LAX) to McGhee Tyson Airport (TYS) on this domestic short-haul route. Whether you prefer full-service or budget airlines, you can easily compare options to find the best itinerary that suits your budget and travel plans. Get ready to discover Knoxville's renowned attractions and neighborhoods while finding all the essential details for flights from Los Angeles to Knoxville.

  • Fastest flight duration: around 7 hours non-stop
  • Route distance: roughly 1,900 miles (3,060 km)
  • Flights per week: around 15+ flights with multiple daily departures on average
  • Typical fares (one-way): economy tickets often range from $125–$470, depending on seasonality and how far ahead you book

Flights from Los Angeles International Airport (LAX) to McGhee Tyson Airport (TYS)

According to recent travel bookings, the top airlines favored by passengers flying from Los Angeles to Knoxville offer both one-stop and non-stop options. Common layover spots include Dallas-Fort Worth International Airport (DFW) with a layover of about 1 hour and 15 minutes, Charlotte-Douglas International Airport (CLT) also at around 1 hour and 15 minutes, and Denver International Airport (DEN) with a shorter layover of about 1 hour. This variety allows travelers to tailor their itineraries by balancing price, total travel time, and cabin class.

  • American Airlines: As a premier full-service airline, it provides one-stop options with one-way ticket prices generally between $145 and $570. This carrier represents around 50% of all departures for this route, featuring an in-flight duration of 5 hours and 30 minutes, leading to a total travel time of about 6 hours and 45 minutes, including layover.
  • Delta: This full-service airline also offers one-stop flights, with one-way fares usually priced from $145 to $545. Delta accounts for approximately 22% of the departures along this route, featuring an in-flight time of 5 hours and 30 minutes, and a total journey time of roughly 6 hours and 45 minutes, including layover.
  • United: Offering both non-stop and one-stop services, United is a full-service airline with one-way fares ranging from $150 to $615. It makes up about 21% of the departures on this route, with a standard one-stop flight time of 5 hours and 30 minutes, culminating in an overall travel duration of approximately 6 hours and 45 minutes.
  • Frontier Airlines: This budget airline provides one-stop options, with one-way fares typically falling between $125 and $300. Frontier accounts for around 7% of departures on this route, featuring an in-flight duration of 5 hours and 30 minutes, resulting in a total journey time of about 6 hours and 45 minutes, including a layover.

Travelers can enhance their journey from Los Angeles to Knoxville by upgrading their flight. American Airlines offers first-class seating, while Delta provides both first class and premium economy options. United also features first-class service for a more comfortable experience.

Best time to fly from Los Angeles (LAX) to Knoxville (TYS)

The most popular months for travelers flying from Los Angeles to Knoxville are March, April, and November, when peak temperatures in Knoxville reach up to 57.6°F in April. If you prefer quieter travel, consider May, the least busy and relatively cheaper time to visit with fewer crowds and temperatures around 66.4°F. For better deals, July usually offers the lowest average one-way fare around $234. Flight availability peaks in November, with approximately 26 flights per week, making it easier to find convenient departure times. January has the fewest flights, with approximately 10 flights per week.

  • Cheapest time to fly: July usually offers good deals with average one-way fare around $234, roughly 19% cheaper than the yearly average.
  • Another budget-friendly time to fly: August typically offers an average one-way fare of around $252.
  • Most flight options: November has the highest number of flights from Los Angeles to Knoxville, with approximately 26 flights per week, giving you more flexibility in scheduling your trip.
calendar iconMonthtemperature iconTemperaturecrowd level iconDemandflights iconWeekly Flightsprice iconAverage one-way Fare
January37.8°F (3.2°C)Moderately Low10$320
February42.4°F (5.8°C)Moderately Low13$304
March49.5°F (9.7°C)Moderately High15$352
April57.6°F (14.2°C)Moderately High16$277
May66.4°F (19.1°C)Moderately Low18$290
June74.1°F (23.4°C)Average19$296
July77.0°F (25.0°C)Average20$234
August75.7°F (24.3°C)Average23$252
September70.3°F (21.3°C)Average18$289
October59.5°F (15.3°C)Average22$294
November48.6°F (9.2°C)Moderately High26$279
December43.0°F (6.1°C)Average20$275

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

Alternative routes from Los Angeles (LAX) to Knoxville (TYS)

  • Burbank to Knoxville (BUR-TYS): Hollywood Burbank Airport (BUR) is located approximately 18 miles from Los Angeles International Airport (LAX). One-way economy tickets for this journey generally fall within the $145 to $460 range, varying with the season and time of booking. This route is commonly served by both one-stop and multi-stop flights, with frequent layovers at Dallas-Fort Worth International Airport (DFW) and Hartsfield-Jackson Atlanta International Airport (ATL). Major airlines operating on this route include American Airlines and Delta, and first-class service is also offered.
  • Los Angeles to Chattanooga (LAX-CHA): Chattanooga Metropolitan Airport (CHA) lies about 86 miles from McGhee Tyson Airport (TYS). The one-way economy fares for this trip usually range from $135 to $485, depending on the season and how far in advance you book. This route typically features one-stop flights, with common layover locations at Hartsfield-Jackson Atlanta International Airport (ATL) and Dallas-Fort Worth International Airport (DFW). Key airlines serving this route are American Airlines and Delta, with business and first-class service available as well.

How to find the best prices for flights from Los Angeles (LAX) to Knoxville (TYS)

Getting some of the best deals on flights from Los Angeles to Knoxville is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are typically available when booking at least two months in advance, although most travelers tend to book between two to eight weeks ahead. Morning departures, from 5 a.m. to 12 p.m., not only offer lower prices but are also the most popular flight times. Additionally, flying on Thursday provides both affordability and popularity among travelers.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.* Find Knoxville hotel and flight deals.
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Frequently asked questions

How much does a flight from Los Angeles, CA (LAX-Los Angeles Intl.) to Knoxville, TN (TYS-McGhee Tyson) cost?
You can find cheap one-way flights from $182 and cheap return flights from $363 Los Angeles, CA (LAX-Los Angeles Intl.) to Knoxville, TN (TYS-McGhee Tyson) with Expedia. One-way flights generally range between $174 and $861, and roundtrip flights usually range from $418 to $1473. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Los Angeles, CA (LAX-Los Angeles Intl.) to Knoxville, TN (TYS-McGhee Tyson) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Los Angeles, CA (LAX-Los Angeles Intl.) to Knoxville, TN (TYS-McGhee Tyson)?
The cheapest month to fly from LAX to TYS is October when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Los Angeles, CA (LAX-Los Angeles Intl.) to Knoxville, TN (TYS-McGhee Tyson)?
Enter LAX to TYS and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Los Angeles, CA (LAX-Los Angeles Intl.) to Knoxville, TN (TYS-McGhee Tyson)?
Southwest Airlines is one of the cheapest airlines offering connecting flights from Los Angeles, CA (LAX) to Knoxville, TN (TYS), with return tickets starting from around $569 with a layover in Las Vegas (LAS). Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Los Angeles, CA (LAX-Los Angeles Intl.) to Knoxville, TN (TYS-McGhee Tyson)?
To find a cheap flight from Los Angeles, CA (LAX-Los Angeles Intl.) to Knoxville, TN (TYS-McGhee Tyson), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Los Angeles, CA (LAX-Los Angeles Intl.) to Knoxville, TN (TYS-McGhee Tyson)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Los Angeles, CA (LAX-Los Angeles Intl.) to Knoxville, TN (TYS-McGhee Tyson)?
The earliest flight from Los Angeles International Airport (LAX) to McGhee Tyson Airport (TYS) usually departs at around 12:05 AM local time, operated by United Airlines. This seasonal service is available in July, giving you an early start to your journey to Knoxville. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Los Angeles, CA (LAX-Los Angeles Intl.) to Knoxville, TN (TYS-McGhee Tyson)?
The most popular departure times for flights from Los Angeles, CA (LAX) to Knoxville, TN (TYS) are in the early morning, from 6am to 9am. About 30% of passengers prefer this time window. Many major carriers, including American Airlines, United Airlines, and Delta Airlines, offer flights during this window. This timing is favored as it allows you to arrive in Knoxville with a full day ahead of you.
How long does it take to fly from Los Angeles, CA (LAX-Los Angeles Intl.) to Knoxville, TN (TYS-McGhee Tyson)?
Flying from LAX to TYS with a connection usually takes about 6 hours 50 minutes, traveling roughly 1,945 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Los Angeles, CA (LAX-Los Angeles Intl.) to Knoxville, TN (TYS-McGhee Tyson)?
You can fly first class between LAX and TYS. First class cabins are available on:

  • United Airlines
  • American Airlines
  • Delta Air Lines

How do I earn miles on a Los Angeles, CA (LAX-Los Angeles Intl.) to Knoxville, TN (TYS-McGhee Tyson) flight with Expedia?
It's easy to earn miles on a Los Angeles, CA (LAX-Los Angeles Intl.) to Knoxville, TN (TYS-McGhee Tyson) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Knoxville from Los Angeles Intl. (LAX)?
From Los Angeles Intl. (LAX), you can fly into McGhee Tyson (TYS) to reach Knoxville. Some flights may connect through major hubs like Sky Harbor Intl. (PHX), Harry Reid Intl. (LAS), Seattle - Tacoma Intl. (SEA) before reaching Knoxville. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Los Angeles, CA (LAX-Los Angeles Intl.) to Knoxville, TN (TYS-McGhee Tyson) at the last minute?
Typically, booking a last minute flight from Los Angeles, CA (LAX-Los Angeles Intl.) to Knoxville, TN (TYS-McGhee Tyson) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Los Angeles, CA (LAX-Los Angeles Intl.) to Knoxville, TN (TYS-McGhee Tyson) flight and hotel package?
Securing a Los Angeles, CA (LAX-Los Angeles Intl.) to Knoxville, TN (TYS-McGhee Tyson) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Los Angeles, CA (LAX-Los Angeles Intl.) to Knoxville, TN (TYS-McGhee Tyson)?
If you booked your Los Angeles, CA (LAX-Los Angeles Intl.) to Knoxville, TN (TYS-McGhee Tyson) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Los Angeles Intl.
Destination airport
McGhee Tyson
Airlines serving
Alaska Airlines, American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$362
Distance
1944 mi

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*Flight schedules are subject to change.

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