$398 Cheap Flights from St. Louis (STL) to Brussels (BRU)

View $398 flight on Fri, Dec 5, 2025Opens in a new window

Popular airlines from St. Louis Lambert Intl. Airport (STL) to Brussels Airport (BRU)

Cheap Flights from St. Louis to Brussels (STL-BRU)

Prices were available within the past 7 days and start at $398 for one-way flights and $501 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Sun, Dec 7 - Wed, Dec 24
STL
St. Louis
BRU
Brussels
$501 Roundtrip, found 2 hours ago
$501
Roundtrip
found 2 hours ago
Select United flight, departing Sun, Dec 7 from St. Louis to Brussels, returning Wed, Dec 24, priced at $501 found 2 hours ago
United
Fri, Nov 28 - Wed, Dec 10
STL
St. Louis
BRU
Brussels
$503 Roundtrip, found 2 hours ago
$503
Roundtrip
found 2 hours ago
Select United flight, departing Fri, Nov 28 from St. Louis to Brussels, returning Wed, Dec 10, priced at $503 found 2 hours ago
United
Wed, Dec 31 - Wed, Jan 14
STL
St. Louis
BRU
Brussels
$504 Roundtrip, found 2 hours ago
$504
Roundtrip
found 2 hours ago
Select United flight, departing Wed, Dec 31 from St. Louis to Brussels, returning Wed, Jan 14, priced at $504 found 2 hours ago
Air Canada
Wed, Jan 14 - Sun, Jan 18
STL
St. Louis
BRU
Brussels
$506 Roundtrip, found 4 hours ago
$506
Roundtrip
found 4 hours ago
Select Air Canada flight, departing Wed, Jan 14 from St. Louis to Brussels, returning Sun, Jan 18, priced at $506 found 4 hours ago
United
Fri, Dec 5 - Sun, Dec 14
STL
St. Louis
BRU
Brussels
$506 Roundtrip, found 2 hours ago
$506
Roundtrip
found 2 hours ago
Select United flight, departing Fri, Dec 5 from St. Louis to Brussels, returning Sun, Dec 14, priced at $506 found 2 hours ago
Air Canada
Fri, Nov 28 - Mon, Dec 8
STL
St. Louis
BRU
Brussels
$507 Roundtrip, found 2 hours ago
$507
Roundtrip
found 2 hours ago
Select Air Canada flight, departing Fri, Nov 28 from St. Louis to Brussels, returning Mon, Dec 8, priced at $507 found 2 hours ago
Air Canada
Wed, Jan 14 - Sun, Jan 18
STL
St. Louis
BRU
Brussels
$510 Roundtrip, found 4 hours ago
$510
Roundtrip
found 4 hours ago
Select Air Canada flight, departing Wed, Jan 14 from St. Louis to Brussels, returning Sun, Jan 18, priced at $510 found 4 hours ago
Lufthansa
Sat, Jan 17 - Sat, Jan 24
STL
St. Louis
BRU
Brussels
$515 Roundtrip, found 1 day ago
$515
Roundtrip
found 1 day ago
Select Lufthansa flight, departing Sat, Jan 17 from St. Louis to Brussels, returning Sat, Jan 24, priced at $515 found 1 day ago
Delta
Mon, Dec 1 - Mon, Dec 15
STL
St. Louis
BRU
Brussels
$522 Roundtrip, found 2 hours ago
$522
Roundtrip
found 2 hours ago
Select Delta flight, departing Mon, Dec 1 from St. Louis to Brussels, returning Mon, Dec 15, priced at $522 found 2 hours ago
American Airlines
Wed, Jan 14 - Sun, Jan 18
STL
St. Louis
BRU
Brussels
$538 Roundtrip, found 4 hours ago
$538
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Wed, Jan 14 from St. Louis to Brussels, returning Sun, Jan 18, priced at $538 found 4 hours ago

Find the cheapest month to fly from St. Louis (STL) to Brussels (BRU)

November is typically the cheapest month to fly

From $558 - $1,763 per traveler.

Alternative airports near Brussels

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Brussels - National BRU. Cheapest and Closest option available. Average driving time to city center is 15 minutes. Flights from $682
BRU
Brussels - National
CheapestClosest
Average driving time to city center15 min
Flights from $682

Frequently asked questions

How much does a flight from Lambert-St. Louis Intl. Airport (STL) to Brussels - National Airport (BRU) cost?
Secure a cheap one-way flight from $398 or cheap return flight from $501 from Lambert-St. Louis Intl. Airport (STL) to Brussels - National Airport (BRU) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Lambert-St. Louis Intl. Airport (STL) to Brussels - National Airport (BRU)?
The cheapest month to fly from STL to BRU is December, when there's less demand. Off-peak months are generally when you'll find lower airfares between these airports.
What is the cheapest airline that flies from Lambert-St. Louis Intl. Airport (STL) to Brussels - National Airport (BRU)?
Expedia's filter tool lets you easily compare different airlines, departure times and fares all in one place. Choose your preferences, then sort by "Price (lowest to highest)" to find the carrier with the cheapest STL to BRU flight.
How many flights per day from Lambert-St. Louis Intl. Airport (STL) to Brussels - National Airport (BRU)?
You'll need to hop on a flight with a layover when traveling from Lambert-St. Louis Intl. Airport (STL) to Brussels - National Airport (BRU). Direct flights don't operate daily on this route. However, just filter your search to include one or more stops to discover an option that works for you.
What day of the week has the most flights from STL to BRU?
Usually you'll find the largest variety of flight choices on a Friday. Tuesdays are often the quietest.* But this can vary based on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Lambert-St. Louis Intl. Airport (STL) to Brussels - National Airport (BRU)?
To touch down at Brussels - National Airport (BRU) on schedule, choose a flight that leaves from Lambert-St. Louis Intl. Airport (STL) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Lambert-St. Louis Intl. Airport (STL) to Brussels - National Airport (BRU) last-minute?
Last-minute fares from STL to BRU are usually more expensive. To lock in the cheapest rates, start looking for flights well ahead of time. That said, if you can play around with your travel dates, you may find a cheap fare right before your journey.
Is it cheaper to book a STL to BRU flight and hotel package?
Securing a STL to BRU flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels in one place. Choose from our impressive range of accommodations and then add car rentals, flights and activities to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Lambert-St. Louis Intl. Airport (STL) to Brussels - National Airport (BRU)?
If you reserved your STL to BRU flight in the last 24 hours, you may be able to cancel or modify it without fees. Depending on the airline and the fare type you purchased, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Lambert-St. Louis Intl.
Destination airport
Brussels - National
Airlines serving
Aer Lingus, Air Canada, American Airlines, Austrian Airlines, British Airways, Brussels Airlines, Delta, Finnair, Iberia, KLM, Lufthansa, Scandinavian Airlines, United
Roundtrip price
$500
Distance
4396 mi

Book with confidence

St. Louis to Brussels Flights

The cheapest times to fly from St. Louis to Brussels

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from St. Louis to Brussels are during the month of December. You can find some of the cheapest flights from St. Louis to Brussels with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from St. Louis to Brussels

Sunday is one of the best days to book for cheap flights from St. Louis to Brussels: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from St. Louis to Brussels

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from St. Louis to Brussels in 2025. You can also book with separate airlines for your outbound and return journeys, from $398 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap St. Louis to Brussels flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your St. Louis to Brussels airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

St. Louis to Brussels Flights

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*Available to One Key members.