$489 Cheap Flights from Antofagasta (ANF) to San Diego (SAN)

View $489 flight on Fri, Sep 26, 2025Opens in a new window

Popular airlines from Antofagasta (ANF-Cerro Moreno Intl.) to San Diego Intl. Airport (SAN)

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Cheap Flights from Antofagasta to San Diego (ANF-SAN)

Prices were available within the past 7 days and start at $489 for one-way flights and for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frequently asked questions

How much does a flight from Cerro Moreno Intl. Airport (ANF) to San Diego Intl. Airport (SAN) cost?
Lock in a cheap one-way flight from $489 or cheap return flight from Cerro Moreno Intl. Airport (ANF) to San Diego Intl. Airport (SAN) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Cerro Moreno Intl. Airport (ANF) to San Diego Intl. Airport (SAN)?
The cheapest month to fly from ANF to SAN is , when there's less demand. Off-peak months are often when better flight deals are available between these airports.
What is the cheapest airline that flies from Cerro Moreno Intl. Airport (ANF) to San Diego Intl. Airport (SAN)?
Expedia's filter tool lets you easily compare different airlines, travel time and fares all in one place. Select your preferences, then sort by "Price (lowest to highest)" to find out which carrier offers the cheapest ANF to SAN flight.
How many flights per day from Cerro Moreno Intl. Airport (ANF) to San Diego Intl. Airport (SAN)?
You'll have to catch a flight with a layover when traveling from Cerro Moreno Intl. Airport (ANF) to San Diego Intl. Airport (SAN). There are no daily direct flights on this route. However, simply filter your search to include one or two stops to find the best option for your trip.
What day of the week has the most flights from ANF to SAN?
Usually you'll find the widest variety of flight choices on a Friday. Tuesdays tend to be the quietest.* However, this can vary depending on the season, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Cerro Moreno Intl. Airport (ANF) to San Diego Intl. Airport (SAN)?
To avoid potential delays on the Cerro Moreno Intl. Airport (ANF) to San Diego Intl. Airport (SAN) route, aim to fly before 3 PM. Later departures have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Cerro Moreno Intl. Airport (ANF) to San Diego Intl. Airport (SAN) last-minute?
Last-minute fares from ANF to SAN are generally more expensive. To lock in the best rates, start looking for flights as early as possible. That said, if you're flexible with your travel plans, you may score a cheap fare right before your journey.
Is it cheaper to book an ANF to SAN flight and hotel package?
You'll generally save money by securing an ANF to SAN flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one place. Once you've chosen your preferred flights and accommodations, consider adding extras such as tours, car rentals and activities.
Can I cancel or change the date of my flight from Cerro Moreno Intl. Airport (ANF) to San Diego Intl. Airport (SAN)?
In most instances, you're able to cancel or reschedule your ANF to SAN flight. However, there may be additional fees, especially if you made your booking more than 24 hours ago. Check your itinerary for the airline's fees and rules on flight changes, or if you need more information, head to our Customer Service portal.

Travel information

Travel information

Origin airport
Cerro Moreno Intl.
Destination airport
San Diego Intl.
Distance
4955 mi

Book with confidence

Book with confidence

Antofagasta to San Diego Flights

The cheapest times to fly from Antofagasta to San Diego

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Antofagasta to San Diego are during the month of . You can find some of the cheapest flights from Antofagasta to San Diego with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Antofagasta to San Diego

Sunday is one of the best days to book for cheap flights from Antofagasta to San Diego: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Antofagasta to San Diego

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Antofagasta to San Diego in 2025. You can also book with separate airlines for your outbound and return journeys, from $489 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Antofagasta to San Diego flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Antofagasta to San Diego airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Antofagasta to San Diego Flights

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